Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Chlorobium limicola DSM 245

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Chlorobiales
Under regulation:
- Genes 32
- Operons 4
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -2702
Score: 98.8
Sequence: TTTTACTGATGAAGC...
Locus tag: Clim_1057
Name: nrdD
Funciton: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Locus tag: Clim_1058
Name: nrdG
Funciton: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
Locus tag: Clim_1059
Name: porB
Funciton: Predicted porin, Gram-negative type
Locus tag: Clim_1060
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: Clim_1061
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: Clim_1062
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: Clim_1063
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
nrdD
Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
nrdG
Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
porB
Predicted porin, Gram-negative type
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter

Position: -492
Score: 74.8
Sequence: GTTCTTTCGTCGTAG...
Locus tag: Clim_1064
Name: btuB7
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: Clim_1065
Name: bluB
Funciton: Cob(II)yrinic acid a,c-diamide reductase
Locus tag: Clim_1066
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: Clim_1067
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: Clim_1068
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Clim_1069
Name: pduO
Funciton: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)
Locus tag: Clim_1070
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: Clim_1071
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Locus tag: Clim_1072
Name: PF01261
Funciton: Xylose isomerase domain protein TIM barrel
btuB7
Outer membrane vitamin B12 receptor BtuB
bluB
Cob(II)yrinic acid a,c-diamide reductase
cbiP
Cobyric acid synthase
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
cbiB
Adenosylcobinamide-phosphate synthase
pduO
Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)
btuC
Vitamin B12 ABC transporter, permease component BtuC
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
PF01261
Xylose isomerase domain protein TIM barrel

Position: -499
Score: 96.6
Sequence: TAAGTAATAACAGTT...
Locus tag: Clim_1023
Name: btuB4
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: Clim_1024
Name: btuF3
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
btuB4
Outer membrane vitamin B12 receptor BtuB
btuF3
Vitamin B12 ABC transporter, B12-binding component BtuF

Position: -509
Score: 74.7
Sequence: TCTTTCTCGTCATAA...
Locus tag: Clim_1001
Name: btuB7
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: Clim_1002
Name: null
Funciton: 4Fe-4S ferredoxin iron-sulfur binding domain protein
Locus tag: Clim_1003
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: Clim_1004
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: Clim_1005
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Locus tag: Clim_1006
Name: btuF2
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: Clim_1007
Name: cbiZ
Funciton: Adenosylcobinamide amidohydrolase (EC 3.5.1.90)
Locus tag: Clim_1008
Name: PF00795
Funciton: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase family protein
Locus tag: Clim_1009
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: Clim_1010
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: Clim_1011
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Clim_1012
Name: cbiHC
Funciton: Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Clim_1013
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: Clim_1014
Name: cbiGF
Funciton: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
btuB7
Outer membrane vitamin B12 receptor BtuB
4Fe-4S ferredoxin iron-sulfur binding domain protein
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
btuC
Vitamin B12 ABC transporter, permease component BtuC
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
btuF2
Vitamin B12 ABC transporter, B12-binding component BtuF
cbiZ
Adenosylcobinamide amidohydrolase (EC 3.5.1.90)
PF00795
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase family protein
cobA
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
cbiK
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiHC
Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiET
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiGF
Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
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