Regulon of PerR in Streptococcus pyogenes M1 GAS

Properties
Regulator type:	Transcription factor
TF locus tag:	SPy0187
Regulator family:	FUR
Regulation mode:	repressor
Biological process:	Iron homeostasis; Manganese homeostasis; Oxidative stress response
Effector:	Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide
Regulog:	PerR - Streptococcaceae
Statistics of regulated genes:
- Genes	12
- Operons	6
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 75 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By TF family - FUR
By effector - Iron ion, (Fe2+)
By effector - Manganese ion, (Mn2+)
By effector - Hydrogen peroxide
By pathway - Iron homeostasis
By pathway - Manganese homeostasis
By pathway - Oxidative stress response

Regulated operons
	Locus Tag	Name	Function
Position: -157 Score: 4.7 Sequence: CGATAATGATTCTAA Locus tag: SPy1531 Name: mgrA Funciton: Non-specific DNA-binding protein / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1)
	SPy1531	mgrA	Non-specific DNA-binding protein / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1)
Position: -124 Score: 5.6 Sequence: TTATAATGATTATTA Locus tag: SPy0453 Name: mntA Funciton: Manganese ABC transporter, substrate binding protein Locus tag: SPy0454 Name: mntC Funciton: Manganese ABC transporter, ATP-binding protein Locus tag: SPy0456 Name: mntB Funciton: Manganese ABC transporter, permease protein
	SPy0453	mntA	Manganese ABC transporter, substrate binding protein
	SPy0454	mntC	Manganese ABC transporter, ATP-binding protein
	SPy0456	mntB	Manganese ABC transporter, permease protein
Position: -36 Score: 5.6 Sequence: TAATAATCATTATAA Locus tag: SPy0450 Name: mntR Funciton: Manganese homeostasis transcriptional regulator MntR, DtxR family
	SPy0450	mntR	Manganese homeostasis transcriptional regulator MntR, DtxR family
Position: -228 Score: 4.6 Sequence: TTAGAATGATTATCG Position: -206 Score: 5.2 Sequence: TTTTAATCATTCTAA Locus tag: SPy0386 Name: fhuA Funciton: Ferrichrome ABC transporter, ATP-binding protein Locus tag: SPy0385 Name: fhuD Funciton: Ferrichrome ABC transporter, substrate-binding protein Locus tag: SPy0384 Name: fhuB Funciton: Ferrichrome ABC transporter, permease protein 1 Locus tag: SPy0383 Name: fhuG Funciton: Ferrichrome ABC transporter, permease protein 2
	SPy0386	fhuA	Ferrichrome ABC transporter, ATP-binding protein
	SPy0385	fhuD	Ferrichrome ABC transporter, substrate-binding protein
	SPy0384	fhuB	Ferrichrome ABC transporter, permease protein 1
	SPy0383	fhuG	Ferrichrome ABC transporter, permease protein 2
Position: -154 Score: 5.7 Sequence: TTAGAATCATTTTAA Locus tag: SPy2079 Name: ahpC Funciton: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) Locus tag: SPy2080 Name: ahpF Funciton: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
	SPy2079	ahpC	Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
	SPy2080	ahpF	Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
Position: -97 Score: 5.4 Sequence: TTAGAATGTTTCTAA Position: -64 Score: 5.8 Sequence: TTAGAATTATTATAA Locus tag: SPy1434 Name: pmtA Funciton: Predicted cation transporting ATPase
	SPy1434	pmtA	Predicted cation transporting ATPase

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD