Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of PurR in Actinobacillus pleuropneumoniae serovar 7 str. AP76

Properties
Regulator type: Transcription factor
TF locus tag: APP7_0876
Regulator family: LacI
Regulation mode: repressor
Biological process: Purine metabolism
Effector: Hypoxanthine; Guanine
Regulog: PurR - Pasteurellales
Statistics of regulated genes:
- Genes 13
- Operons 10
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 77 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -69
Score: 5.6
Sequence: GCGCAAACGTTTGCGC
Locus tag: APP7_1137
Name: xanP
Funciton: Xanthine permease
xanP
Xanthine permease

Position: -64
Score: 5.9
Sequence: TCGCAATCGTTTGCGT
Locus tag: APP7_2105
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)

Position: -40
Score: 5.2
Sequence: TAGCAAACGTTTGCAA
Locus tag: APP7_0956
Name: folD
Funciton: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
folD
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)

Position: -82
Score: 6.1
Sequence: ATGCAAACGTTTGCTT
Locus tag: APP7_1129
Name: yjcD
Funciton: Prediceted xanthine/uracil permease
yjcD
Prediceted xanthine/uracil permease

Position: -68
Score: 6.1
Sequence: ATGCAAACGTTTGCGT
Locus tag: APP7_1743
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)

Position: -65
Score: 6.2
Sequence: AAGCAAACGTTTGCGT
Locus tag: APP7_1011
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)

Position: -66
Score: 6
Sequence: AAGCAAACGTTTGCCT
Locus tag: APP7_0699
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: APP7_0700
Name: ansB
Funciton: L-asparaginase (EC 3.5.1.1)
Locus tag: APP7_0701
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
ansB
L-asparaginase (EC 3.5.1.1)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)

Position: -39
Score: 6.3
Sequence: ACGCAAACGTTTGCTT
Locus tag: APP7_1231
Name: purD
Funciton: Phosphoribosylamine-glycine ligase (EC 6.3.4.13)
purD
Phosphoribosylamine-glycine ligase (EC 6.3.4.13)

Position: -49
Score: 5.6
Sequence: GCGCAAACGTTTGCGC
Locus tag: APP7_0213
Name: glyA
Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1)

Position: -55
Score: 6.1
Sequence: ACGCAAACGTTTTCTT
Locus tag: APP7_0448
Name: cvpA
Funciton: Colicin V production protein
Locus tag: APP7_0449
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
cvpA
Colicin V production protein
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
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