Regulon of HypR in Paracoccus denitrificans PD1222

Properties
Regulator type:	Transcription factor
TF locus tag:	Pden_4868
Regulator family:	GntR/Others
Regulation mode:	activator (repressor)
Biological process:	Proline and 4-hydrohyproline utilization
Effector:	4-hydroxyproline
Regulog:	HypR - Rhodobacterales
Statistics of regulated genes:
- Genes	15
- Operons	4
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 10 sites [see more]

Member of regulog collections

By taxonomy - Rhodobacterales
By trascription factor - HypR
By TF family - GntR/Others
By effector - 4-hydroxyproline
By pathway - Proline and 4-hydrohyproline utilization

Regulated operons
	Locus Tag	Name	Function
Position: -53 Score: 4 Sequence: TCATGTATGCAAAA Locus tag: Pden_4866 Name: hypS Funciton: Putative L-lactate/Malate dehydrogenase
	Pden_4866	hypS	Putative L-lactate/Malate dehydrogenase
Position: -88 Score: 4.8 Sequence: CTTTGTCGACAAAT Locus tag: Pden_4867 Name: hypD Funciton: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
	Pden_4867	hypD	1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
Position: -111 Score: 3.5 Sequence: TTTTGTATATTAGT Position: -94 Score: 4 Sequence: TTTTGCATACATGA Locus tag: Pden_4865 Name: hypH Funciton: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible Locus tag: Pden_4864 Name: hypM Funciton: Predicted hydroxyproline ABC transporter, substrate-binding protein Locus tag: Pden_4863 Name: hypN Funciton: Predicted hydroxyproline ABC transporter, permease protein Locus tag: Pden_4862 Name: hypP Funciton: Predicted hydroxyproline ABC transporter, permease protein Locus tag: Pden_4861 Name: hypQ Funciton: Predicted hydroxyproline ABC transporter, ATP-binding protein Locus tag: Pden_4860 Name: hypO Funciton: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster Locus tag: Pden_4859 Name: hypE Funciton: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) Locus tag: Pden_4858 Name: hypA Funciton: Predicted hydroxyproline TRAP-type transport system, small permease component Locus tag: Pden_4857 Name: hypB Funciton: Predicted hydroxyproline TRAP-type transport system, large permease component Locus tag: Pden_4856 Name: hypC Funciton: Predicted hydroxyproline TRAP-type transport system, periplasmic component Locus tag: Pden_4855 Name: hypS Funciton: Putative L-lactate/Malate dehydrogenase Locus tag: Pden_4854 Name: hypX Funciton: Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase
	Pden_4865	hypH	Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
	Pden_4864	hypM	Predicted hydroxyproline ABC transporter, substrate-binding protein
	Pden_4863	hypN	Predicted hydroxyproline ABC transporter, permease protein
	Pden_4862	hypP	Predicted hydroxyproline ABC transporter, permease protein
	Pden_4861	hypQ	Predicted hydroxyproline ABC transporter, ATP-binding protein
	Pden_4860	hypO	D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
	Pden_4859	hypE	Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
	Pden_4858	hypA	Predicted hydroxyproline TRAP-type transport system, small permease component
	Pden_4857	hypB	Predicted hydroxyproline TRAP-type transport system, large permease component
	Pden_4856	hypC	Predicted hydroxyproline TRAP-type transport system, periplasmic component
	Pden_4855	hypS	Putative L-lactate/Malate dehydrogenase
	Pden_4854	hypX	Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase
Position: -41 Score: 3.4 Sequence: AGTTGTCGACGTCA Locus tag: Pden_4868 Name: hypR Funciton: Predicted regulator for proline and hydrohyproline utilization, GntR family
	Pden_4868	hypR	Predicted regulator for proline and hydrohyproline utilization, GntR family

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