Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Geobacillus kaustophilus HTA426

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Bacillales
Under regulation:
- Genes 34
- Operons 3
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -249
Score: 123.9
Sequence: TCGTTGCGCCAAGCA...
Locus tag: GK0911
Name: nrdA
Funciton: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Locus tag: GK0912
Name: nrdB
Funciton: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
GK0911
nrdA
Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
GK0912
nrdB
Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
Position: -378
Score: 117.9
Sequence: TAGGCGAGAAACAAA...
Locus tag: GK1810
Name: cbiW
Funciton: Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
Locus tag: GK1809
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: GK1808
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: GK1807
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: GK1806
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: GK1805
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: GK1804
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: GK1803
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: GK1802
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: GK1801
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic (EC 2.1.1.-)
Locus tag: GK1800
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: GK1799
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: GK1798
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: GK1797
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: GK1796
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: GK1795
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: GK1794
Name: null
Funciton: Transposase
Locus tag: GK1793
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: GK1792
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: GK1791
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
GK1810
cbiW
Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
GK1809
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
GK1808
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
GK1807
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
GK1806
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter
GK1805
cbiH
Cobalt-precorrin-3b C17-methyltransferase
GK1804
cbiX
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
GK1803
cbiJ
Cobalt-precorrin-6x reductase (EC 1.3.1.54)
GK1802
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
GK1801
cbiD
Cobalt-precorrin-6 synthase, anaerobic (EC 2.1.1.-)
GK1800
cbiET
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
GK1799
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
GK1798
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
GK1797
cbiG
Cobalamin biosynthesis protein CbiG
GK1796
cbiA
Cobyrinic acid A,C-diamide synthase
GK1795
cbiP
Cobyric acid synthase
GK1794
Transposase
GK1793
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
GK1792
cobA
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
GK1791
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Position: -341
Score: 122.2
Sequence: CTAAATCAACTCGCA...
Locus tag: GK2266
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: GK2265
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: GK2264
Name: btuD-cbiZ
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD / Adenosylcobinamide amidohydrolase (EC 3.5.1.90)
Locus tag: GK2263
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: GK2262
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: GK2261
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: GK2260
Name: cobS
Funciton: Cobalamin synthase
Locus tag: GK2259
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: GK2258
Name: cobU2
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: GK2257
Name: pduO
Funciton: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)
Locus tag: GK2256
Name: cblT
Funciton: Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole
Locus tag: GK2255
Name: cblS
Funciton: Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis
GK2266
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
GK2265
btuC
Vitamin B12 ABC transporter, permease component BtuC
GK2264
btuD-cbiZ
Vitamin B12 ABC transporter, ATPase component BtuD / Adenosylcobinamide amidohydrolase (EC 3.5.1.90)
GK2263
cbiB
Adenosylcobinamide-phosphate synthase
GK2262
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
GK2261
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
GK2260
cobS
Cobalamin synthase
GK2259
cobC
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
GK2258
cobU2
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
GK2257
pduO
Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)
GK2256
cblT
Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole
GK2255
cblS
Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis
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