Regulon of Cobalamin in Anoxybacillus flavithermus WK1

Properties
Regulator type:	RNA regulatory element
Name:	Cobalamin
RFAM:	RF00174
Regulation mode:
Biological process:	Cobalamin biosynthesis
Effector:	Adenosylcobalamin
Regulog:	Cobalamin - Bacillales
Under regulation:
- Genes	35
- Operons	3

Member of regulog collections

By taxonomy - Bacillales
By RNA motif - Cobalamin
By effector - Adenosylcobalamin
By pathway - Cobalamin biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -316 Score: 121.4 Sequence: ATTGAAACCAACAAG... Locus tag: Aflv_0393 Name: nrdA Funciton: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1) Locus tag: Aflv_0392 Name: null Funciton: transposase Locus tag: Aflv_0391 Name: null Funciton: Flavodoxin Locus tag: Aflv_0390 Name: nrdB Funciton: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
	Aflv_0393	nrdA	Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
	Aflv_0392		transposase
	Aflv_0391		Flavodoxin
	Aflv_0390	nrdB	Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
Position: -317 Score: 111.8 Sequence: ATATACGATCAGCAA... Locus tag: Aflv_2185 Name: cbiW Funciton: Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis Locus tag: Aflv_2184 Name: cbiM Funciton: Substrate-specific component CbiM of cobalt ECF transporter Locus tag: Aflv_2183 Name: cbiN Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter Locus tag: Aflv_2182 Name: cbiQ Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter Locus tag: Aflv_2181 Name: cbiO Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter Locus tag: Aflv_2180 Name: cbiH Funciton: Cobalt-precorrin-3b C17-methyltransferase Locus tag: Aflv_2179 Name: cbiX Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) Locus tag: Aflv_2178 Name: cbiJ Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54) Locus tag: Aflv_2177 Name: cbiC Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) Locus tag: Aflv_2176 Name: cbiD Funciton: Cobalt-precorrin-6 synthase, anaerobic (EC 2.1.1.-) Locus tag: Aflv_2175 Name: cbiET Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) Locus tag: Aflv_2174 Name: cbiL Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) Locus tag: Aflv_2173 Name: cbiF Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) Locus tag: Aflv_2172 Name: cbiG Funciton: Cobalamin biosynthesis protein CbiG Locus tag: Aflv_2171 Name: cbiA Funciton: Cobyrinic acid A,C-diamide synthase Locus tag: Aflv_2170 Name: cbiP Funciton: Cobyric acid synthase Locus tag: Aflv_2169 Name: cobT Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) Locus tag: Aflv_2168 Name: cobA Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) Locus tag: Aflv_2167 Name: btuR Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
	Aflv_2185	cbiW	Putative 2Fe-2S ferredoxin CbiW involved in B12 biosynthesis
	Aflv_2184	cbiM	Substrate-specific component CbiM of cobalt ECF transporter
	Aflv_2183	cbiN	Additional substrate-specific component CbiN of cobalt ECF transporter
	Aflv_2182	cbiQ	Transmembrane component CbiQ of energizing module of cobalt ECF transporter
	Aflv_2181	cbiO	ATPase component CbiO of energizing module of cobalt ECF transporter
	Aflv_2180	cbiH	Cobalt-precorrin-3b C17-methyltransferase
	Aflv_2179	cbiX	Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
	Aflv_2178	cbiJ	Cobalt-precorrin-6x reductase (EC 1.3.1.54)
	Aflv_2177	cbiC	Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
	Aflv_2176	cbiD	Cobalt-precorrin-6 synthase, anaerobic (EC 2.1.1.-)
	Aflv_2175	cbiET	Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
	Aflv_2174	cbiL	Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
	Aflv_2173	cbiF	Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
	Aflv_2172	cbiG	Cobalamin biosynthesis protein CbiG
	Aflv_2171	cbiA	Cobyrinic acid A,C-diamide synthase
	Aflv_2170	cbiP	Cobyric acid synthase
	Aflv_2169	cobT	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
	Aflv_2168	cobA	Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
	Aflv_2167	btuR	Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Position: -396 Score: 131.9 Sequence: TATGTCCGTTGCAAA... Locus tag: Aflv_1041 Name: btuF Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF Locus tag: Aflv_1042 Name: btuC Funciton: Vitamin B12 ABC transporter, permease component BtuC Locus tag: Aflv_1043 Name: btuD-cbiZ Funciton: Vitamin B12 ABC transporter, ATPase component BtuD / Adenosylcobinamide amidohydrolase (EC 3.5.1.90) Locus tag: Aflv_1044 Name: cbiB Funciton: Adenosylcobinamide-phosphate synthase Locus tag: Aflv_1045 Name: cobD Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) Locus tag: Aflv_1046 Name: cobU Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) Locus tag: Aflv_1047 Name: cobS Funciton: Cobalamin synthase Locus tag: Aflv_1048 Name: cobC Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73) Locus tag: Aflv_1049 Name: cobU2 Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) Locus tag: Aflv_1050 Name: pduO Funciton: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17) Locus tag: Aflv_1051 Name: cblT Funciton: Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole Locus tag: Aflv_1052 Name: cblS Funciton: Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis
	Aflv_1041	btuF	Vitamin B12 ABC transporter, B12-binding component BtuF
	Aflv_1042	btuC	Vitamin B12 ABC transporter, permease component BtuC
	Aflv_1043	btuD-cbiZ	Vitamin B12 ABC transporter, ATPase component BtuD / Adenosylcobinamide amidohydrolase (EC 3.5.1.90)
	Aflv_1044	cbiB	Adenosylcobinamide-phosphate synthase
	Aflv_1045	cobD	L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
	Aflv_1046	cobU	Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
	Aflv_1047	cobS	Cobalamin synthase
	Aflv_1048	cobC	Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
	Aflv_1049	cobU2	Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
	Aflv_1050	pduO	Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)
	Aflv_1051	cblT	Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole
	Aflv_1052	cblS	Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of Cobalamin in Anoxybacillus flavithermus WK1

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --