Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Shewanella sediminis HAW-EB3

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Shewanellaceae
Under regulation:
- Genes 36
- Operons 5
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -277
Score: 90
Sequence: TTTTACTCTTTGAAA...
Locus tag: Ssed_2092
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: Ssed_2093
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: Ssed_2094
Name: Ssed_2094
Funciton: Additional component of cobalt ECF transporter
Locus tag: Ssed_2095
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: Ssed_2096
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
Ssed_2094
Additional component of cobalt ECF transporter
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter

Position: -334
Score: 112.2
Sequence: AATTTTAACATTATC...
Locus tag: Ssed_2080
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: Ssed_2081
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Ssed_2082
Name: cbiET
Funciton: CoCobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: Ssed_2083
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Ssed_2084
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: Ssed_2085
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: Ssed_2086
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Ssed_2087
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: Ssed_2088
Name: cysG
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: Ssed_2089
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Ssed_2090
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
cbiD
Cobalt-precorrin-6 synthase, anaerobic
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiET
CoCobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiG
Cobalamin biosynthesis protein CbiG
cbiK
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
cbiH
Cobalt-precorrin-3b C17-methyltransferase
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cysG
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
cbiB
Adenosylcobinamide-phosphate synthase
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)

Position: -339
Score: 96.5
Sequence: ATATTCGCATCGACT...
Locus tag: Ssed_2165
Name: btuB
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: Ssed_2164
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Locus tag: Ssed_2163
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: Ssed_2162
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Ssed_2161
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: Ssed_2160
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Ssed_2159
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: Ssed_2158
Name: cobT2
Funciton: Predicted nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Ssed_2157
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: Ssed_2156
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: Ssed_2155
Name: cobS
Funciton: Cobalamin synthase
Locus tag: Ssed_2154
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
btuB
Outer membrane vitamin B12 receptor BtuB
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
btuC
Vitamin B12 ABC transporter, permease component BtuC
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cobC
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
cobT2
Predicted nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cbiP
Cobyric acid synthase
cbiA
Cobyrinic acid A,C-diamide synthase
cobS
Cobalamin synthase
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)

Position: -361
Score: 59
Sequence: TATGCTGTCAATCTT...
Locus tag: Ssed_3559
Name: btuB
Funciton: Outer membrane vitamin B12 receptor BtuB
btuB
Outer membrane vitamin B12 receptor BtuB

Position: -534
Score: 59.1
Sequence: GGAGAGGATCGCAAA...
Locus tag: Ssed_3736
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Locus tag: Ssed_3735
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: Ssed_3734
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: Ssed_3733
Name: cobS
Funciton: Cobalamin synthase
Locus tag: Ssed_3732
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Ssed_3731
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: Ssed_3730
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
btuC
Vitamin B12 ABC transporter, permease component BtuC
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cobS
Cobalamin synthase
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cbiP
Cobyric acid synthase
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
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