Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CymR in Anoxybacillus flavithermus WK1

Properties
Regulator type: Transcription factor
TF locus tag: Aflv_0736
Regulator family: Rrf2
Regulation mode: repressor
Biological process: Cysteine metabolism
Effector: O-acetyl-L-serine; CysK, cysteine synthetase
Regulog: CymR - Bacillales
Statistics of regulated genes:
- Genes 16
- Operons 6
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 65 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -112
Score: 5.4
Sequence: CTATTCCTATAAATCAAGTATGTTTTA
Locus tag: Aflv_1598
Name: cysL
Funciton: Regulator of sulfur assimilation, activates cysJI expression
cysL
Regulator of sulfur assimilation, activates cysJI expression

Position: -36
Score: 6.4
Sequence: TAATTCATACTATACTTATAGGAATTA
Locus tag: Aflv_0758
Name: yrrT
Funciton: SAM-dependent methyltransferase
Locus tag: Aflv_0759
Name: mtn
Funciton: 5'-methylthioadenosine nucleosidase (EC 3.2.2.16) / S-adenosylhomocysteine nucleosidase (EC 3.2.2.9)
Locus tag: Aflv_0760
Name: mccA
Funciton: Cystathionine beta-synthase (EC 4.2.1.22)
Locus tag: Aflv_0761
Name: mccB
Funciton: Cystathionine gamma-lyase (EC 4.4.1.1)
Locus tag: Aflv_0762
Name: yrhC
Funciton: Hypothetical protein
yrrT
SAM-dependent methyltransferase
mtn
5'-methylthioadenosine nucleosidase (EC 3.2.2.16) / S-adenosylhomocysteine nucleosidase (EC 3.2.2.9)
mccA
Cystathionine beta-synthase (EC 4.2.1.22)
mccB
Cystathionine gamma-lyase (EC 4.4.1.1)
yrhC
Hypothetical protein

Position: -48
Score: 5.4
Sequence: TAAAACATACTTGATTTATAGGAATAG
Locus tag: Aflv_1597
Name: cysJ
Funciton: Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)
Locus tag: Aflv_1596
Name: yvgQ
Funciton: Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)
cysJ
Sulfite reductase [NADPH] flavoprotein alpha-component (EC 1.8.1.2)
yvgQ
Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)

Position: -100
Score: 5.1
Sequence: AAATTCCGATAGAAAAACTAGGATTGA
Locus tag: Aflv_0316
Name: cysH
Funciton: Phosphoadenylyl-sulfate reductase (EC 1.8.4.8)
Locus tag: Aflv_0315
Name: cysP
Funciton: Sulfate permease, Pit-type
cysH
Phosphoadenylyl-sulfate reductase (EC 1.8.4.8)
cysP
Sulfate permease, Pit-type

Position: -48
Score: 5.6
Sequence: TTAATCCTAGTTGTTTTATAAGAATAA
Locus tag: Aflv_0314
Name: sat
Funciton: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
Locus tag: Aflv_0313
Name: cysC
Funciton: Adenylylsulfate kinase (EC 2.7.1.25)
Locus tag: Aflv_0312
Name: ylnD
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: Aflv_0311
Name: sirB
Funciton: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
Locus tag: Aflv_0310
Name: sirC
Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
sat
Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
cysC
Adenylylsulfate kinase (EC 2.7.1.25)
ylnD
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
sirB
Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
sirC
Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)

Position: -30
Score: 5
Sequence: CAAATTCTATAAAAATACTCGGGATTA
Locus tag: Aflv_0065
Name: cysK
Funciton: Cysteine synthase (EC 2.5.1.47)
cysK
Cysteine synthase (EC 2.5.1.47)
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