Regulon of DosR in Mycobacterium vanbaalenii PYR-1

Properties
Regulator type:	Transcription factor
TF locus tag:	Mvan_2548, Mvan_1427
Regulator family:	LuxR
Regulation mode:	activator
Biological process:	Dormancy
Effector:	Oxygen; Carbon monoxide; Nitric oxide
Regulog:	DosR - Actinomycetales
Statistics of regulated genes:
- Genes	54
- Operons	25
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 299 sites [see more]

Member of regulog collections

By TF family - LuxR
By effector - Oxygen
By effector - Carbon monoxide
By effector - Nitric oxide
By pathway - Dormancy

Regulated operons
	Locus Tag	Name	Function
Position: -52 Score: 4.3 Sequence: AAGGGACCTTTGGCCCAC Locus tag: Mvan_0299 Name: fdxA Funciton: 4Fe-4S ferredoxin, iron-sulfur binding protein
	Mvan_0299	fdxA	4Fe-4S ferredoxin, iron-sulfur binding protein
Position: -101 Score: 3.9 Sequence: TAGAGACGAAAGTCACCC Position: -73 Score: 3.9 Sequence: TGGTGGCTTAGGTCCCTG Locus tag: Mvan_1405 Name: null Funciton: hypothetical protein Locus tag: Mvan_1404 Name: null Funciton: hypothetical protein, eRF1_3 family
	Mvan_1405		hypothetical protein
	Mvan_1404		hypothetical protein, eRF1_3 family
Position: -200 Score: 4.8 Sequence: ACGGGACCAACGGCCCTA Locus tag: Mvan_1415 Name: usp Funciton: universal stress protein Locus tag: Mvan_1416 Name: null Funciton: hypothetical protein
	Mvan_1415	usp	universal stress protein
	Mvan_1416		hypothetical protein
Position: -52 Score: 4.3 Sequence: CGATGACCTTAGGCCCTA Locus tag: Mvan_1377 Name: null Funciton: hypothetical protein Locus tag: Mvan_1378 Name: usp Funciton: universal stress protein Locus tag: Mvan_1379 Name: null Funciton: putative conserved transmembrane protein Locus tag: Mvan_1380 Name: Mmcs_1073 Funciton: alcohol dehydrogenase GroES-like protein Locus tag: Mvan_1381 Name: usp Funciton: universal stress protein
	Mvan_1377		hypothetical protein
	Mvan_1378	usp	universal stress protein
	Mvan_1379		putative conserved transmembrane protein
	Mvan_1380	Mmcs_1073	alcohol dehydrogenase GroES-like protein
	Mvan_1381	usp	universal stress protein
Position: -124 Score: 4.4 Sequence: AAGGGCCGAAAGTCCCAC Locus tag: Mvan_1397 Name: null Funciton: hypothetical protein
	Mvan_1397		hypothetical protein
Position: -79 Score: 4 Sequence: TAGGGCACAAAGTCACCG Locus tag: Mvan_4722 Name: DGAT Funciton: wax-dgat acyltransferase
	Mvan_4722	DGAT	wax-dgat acyltransferase
Position: -89 Score: 4 Sequence: CGGGGTCGAAGTGCCCTT Locus tag: Mvan_1421 Name: dosS Funciton: two-component sensor histidine kinase, DosS Locus tag: Mvan_1422 Name: Mmcs_1099 Funciton: magnesium and cobalt efflux protein CorC Locus tag: Mvan_1423 Name: merR2 Funciton: HAD-superfamily hydrolase subfamily IIB
	Mvan_1421	dosS	two-component sensor histidine kinase, DosS
	Mvan_1422	Mmcs_1099	magnesium and cobalt efflux protein CorC
	Mvan_1423	merR2	HAD-superfamily hydrolase subfamily IIB
Position: -279 Score: 3.7 Sequence: TACGGCCGAAAGTCCACG Locus tag: Mvan_4728 Name: acrA1_1 Funciton: multi-functional enzyme with acyl-CoA-reductase activity AcrA1_1
	Mvan_4728	acrA1_1	multi-functional enzyme with acyl-CoA-reductase activity AcrA1_1
Position: -74 Score: 4.5 Sequence: CAGGGCCAATGGTCCTCA Locus tag: Mvan_1384 Name: Rv2004c Funciton: hypothetical protein
	Mvan_1384	Rv2004c	hypothetical protein
Position: -71 Score: 4.5 Sequence: TGAGGACCATTGGCCCTG Locus tag: Mvan_1383 Name: acg Funciton: nitroreductase Locus tag: Mvan_1382 Name: Rv3134c Funciton: universal stress protein
	Mvan_1383	acg	nitroreductase
	Mvan_1382	Rv3134c	universal stress protein
Position: -80 Score: 4.1 Sequence: CGATGACCAATGGCCCTA Locus tag: Mvan_1387 Name: usp Funciton: universal stress protein Locus tag: Mvan_1386 Name: usp Funciton: universal stress protein Locus tag: Mvan_1385 Name: MMAR_3503 Funciton: metal cation transporter p-type ATPase
	Mvan_1387	usp	universal stress protein
	Mvan_1386	usp	universal stress protein
	Mvan_1385	MMAR_3503	metal cation transporter p-type ATPase
Position: -98 Score: 3.9 Sequence: CAGAGTCCGAGGTCCTTC Position: -75 Score: 4.3 Sequence: CGGGGACCTGCGGCCCTA Locus tag: Mvan_1427 Name: dosR Funciton: two component transcriptional regulator, DosR
	Mvan_1427	dosR	two component transcriptional regulator, DosR
Position: -126 Score: 4.3 Sequence: TAGGGCCGCAGGTCCCCG Position: -103 Score: 3.9 Sequence: GAAGGACCTCGGACTCTG Locus tag: Mvan_1426 Name: Mmcs_1103 Funciton: MgtE integral membrane region
	Mvan_1426	Mmcs_1103	MgtE integral membrane region
Position: -72 Score: 4.5 Sequence: TGAGGACCATTGGCCCTG Locus tag: Mvan_2550 Name: nitroreductase Funciton: nitroreductase Locus tag: Mvan_2549 Name: usp Funciton: universal stress protein Locus tag: Mvan_2548 Name: dosR Funciton: two component transcriptional regulator, DosR
	Mvan_2550	nitroreductase	nitroreductase
	Mvan_2549	usp	universal stress protein
	Mvan_2548	dosR	two component transcriptional regulator, DosR
Position: -111 Score: 3.5 Sequence: GCGGGTCGGCCGTCCCCT Position: -88 Score: 4.2 Sequence: GGGTGACCTTCGGCCCTG Locus tag: Mvan_4106 Name: null Funciton: pyruvate dikinase Locus tag: Mvan_4107 Name: otsB1 Funciton: trehalose-6-phosphate phosphatase Locus tag: Mvan_4108 Name: gltD Funciton: NADH-dependent glutamate synthase (small subunit) GltD Locus tag: Mvan_4109 Name: null Funciton: Pyruvate:ferredoxin (flavodoxin) oxidoreductase Locus tag: Mvan_4110 Name: null Funciton: dihydroorotate dehydrogenase
	Mvan_4106		pyruvate dikinase
	Mvan_4107	otsB1	trehalose-6-phosphate phosphatase
	Mvan_4108	gltD	NADH-dependent glutamate synthase (small subunit) GltD
	Mvan_4109		Pyruvate:ferredoxin (flavodoxin) oxidoreductase
	Mvan_4110		dihydroorotate dehydrogenase
Position: -72 Score: 4.7 Sequence: CAGGGACTTAGGACCTTT Locus tag: Mvan_4105 Name: pfkB Funciton: probable phosphofructokinase
	Mvan_4105	pfkB	probable phosphofructokinase
Position: -108 Score: 4 Sequence: GAGGGCCGGCGGTCCCGG Position: -74 Score: 3.9 Sequence: CCGGGCCAACGGTCCTCT Locus tag: Mvan_1373 Name: Mmcs_1080 Funciton: hypothetical protein
	Mvan_1373	Mmcs_1080	hypothetical protein
Position: -87 Score: 4.3 Sequence: GGAGGACTTCAGTCCCTA Locus tag: Mvan_1374 Name: hspX Funciton: heat shock protein HspX_1
	Mvan_1374	hspX	heat shock protein HspX_1
Position: -75 Score: 4.3 Sequence: TAGGGACTGAAGTCCTCC Locus tag: Mvan_1375 Name: null Funciton: ATPase, P-type (transporting), HAD superfamily, subfamily IC Locus tag: Mvan_1376 Name: null Funciton: hypothetical protein
	Mvan_1375		ATPase, P-type (transporting), HAD superfamily, subfamily IC
	Mvan_1376		hypothetical protein
Position: -97 Score: 3.5 Sequence: CACGGACTTTAGCCTCTA Locus tag: Mvan_0443 Name: null Funciton: iron-containing alcohol dehydrogenase Locus tag: Mvan_0444 Name: DGAT Funciton: wax-dgat acyltransferase
	Mvan_0443		iron-containing alcohol dehydrogenase
	Mvan_0444	DGAT	wax-dgat acyltransferase
Position: -138 Score: 4.7 Sequence: AAAGGTCCTAAGTCCCTG Locus tag: Mvan_4104 Name: DGAT Funciton: wax-dgat acyltransferase Locus tag: Mvan_4103 Name: DGAT Funciton: wax-dgat acyltransferase
	Mvan_4104	DGAT	wax-dgat acyltransferase
	Mvan_4103	DGAT	wax-dgat acyltransferase
Position: -105 Score: 3.9 Sequence: CAGGGACCTAAGCCACCA Position: -77 Score: 3.9 Sequence: GGGTGACTTTCGTCTCTA Locus tag: Mvan_1406 Name: MAV_3502 Funciton: hypothetical protein Locus tag: Mvan_1407 Name: acs_1 Funciton: acetyl-coenzyme A synthetase Acs_1 Locus tag: Mvan_1408 Name: phdA Funciton: pyruvate dehydrogenase E1 component (alpha subunit) Locus tag: Mvan_1409 Name: phdB Funciton: pyruvate dehydrogenase E1 component (beta subunit) Locus tag: Mvan_1410 Name: Rv1734c Funciton: pyruvate dehydrogenase (E2 component) Locus tag: Mvan_1411 Name: MMAR_3492 Funciton: hypothetical protein Locus tag: Mvan_1412 Name: Rv2625c Funciton: conserved transmembrane alanine and leucine rich protein Locus tag: Mvan_1413 Name: dosS Funciton: two-component sensor histidine kinase, DosS
	Mvan_1406	MAV_3502	hypothetical protein
	Mvan_1407	acs_1	acetyl-coenzyme A synthetase Acs_1
	Mvan_1408	phdA	pyruvate dehydrogenase E1 component (alpha subunit)
	Mvan_1409	phdB	pyruvate dehydrogenase E1 component (beta subunit)
	Mvan_1410	Rv1734c	pyruvate dehydrogenase (E2 component)
	Mvan_1411	MMAR_3492	hypothetical protein
	Mvan_1412	Rv2625c	conserved transmembrane alanine and leucine rich protein
	Mvan_1413	dosS	two-component sensor histidine kinase, DosS
Position: -274 Score: 4.2 Sequence: AGGGGTCTTTGGTCCTCG Locus tag: Mvan_1393 Name: null Funciton: Erythromycin esterase Locus tag: Mvan_1394 Name: pfkB Funciton: probable phosphofructokinase Locus tag: Mvan_1395 Name: dosT Funciton: two-component system sensor kinase, DosT
	Mvan_1393		Erythromycin esterase
	Mvan_1394	pfkB	probable phosphofructokinase
	Mvan_1395	dosT	two-component system sensor kinase, DosT
Position: -104 Score: 3.9 Sequence: CGGGGCCGAAGGCCTCTA Locus tag: Mvan_1425 Name: usp Funciton: universal stress protein protein
	Mvan_1425	usp	universal stress protein protein
Position: -144 Score: 4.7 Sequence: AGAGGACTTTGGTCCCTG Locus tag: Mvan_1963 Name: usp Funciton: universal stress protein
	Mvan_1963	usp	universal stress protein

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of DosR in Mycobacterium vanbaalenii PYR-1

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --