Regulon of DosR in Mycobacterium tuberculosis H37Rv

Properties
Regulator type:	Transcription factor
TF locus tag:	Rv3133c
Regulator family:	LuxR
Regulation mode:	activator
Biological process:	Dormancy
Effector:	Oxygen; Carbon monoxide; Nitric oxide
Regulog:	DosR - Actinomycetales
Statistics of regulated genes:
- Genes	43
- Operons	25
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 299 sites [see more]

Member of regulog collections

By TF family - LuxR
By effector - Oxygen
By effector - Carbon monoxide
By effector - Nitric oxide
By pathway - Dormancy

Regulated operons
	Locus Tag	Name	Function
Position: -130 Score: 3.5 Sequence: TGAGGACCTAAGCCCGTT Locus tag: Rv2623 Name: Rv2623 usp Funciton: universal stress protein
	Rv2623	Rv2623 usp	universal stress protein
Position: -111 Score: 4.2 Sequence: CTGGACCGTAGGTCCCTG Position: -89 Score: 4 Sequence: GGATGACTTACGGCCCTG Locus tag: Rv1997 Name: ctpF Funciton: cation-transporting ATPase
	Rv1997	ctpF	cation-transporting ATPase
Position: -93 Score: 4.3 Sequence: GGAGGACCTTTGGCCCTG Locus tag: Rv3130c Name: DGAT Funciton: wax-dgat acyltransferase
	Rv3130c	DGAT	wax-dgat acyltransferase
Position: -88 Score: 4.6 Sequence: ATGGGACTTTCGGCCCTG Locus tag: Rv0079 Name: null Funciton: hypothetical protein Locus tag: Rv0080 Name: null Funciton: hypothetical protein
	Rv0079		hypothetical protein
	Rv0080		hypothetical protein
Position: -300 Score: 4.2 Sequence: GGATGACTTTGGTCCCTA Locus tag: Rv2629 Name: null Funciton: hypothetical protein, eRF1_3 family Locus tag: Rv2630 Name: null Funciton: hypothetical protein, archease protein family Locus tag: Rv2631 Name: null Funciton: hypothetical protein
	Rv2629		hypothetical protein, eRF1_3 family
	Rv2630		hypothetical protein, archease protein family
	Rv2631		hypothetical protein
Position: -66 Score: 3.5 Sequence: ATGAGGCTTTAGTCCCCA Locus tag: Rv2006 Name: otsB1 Funciton: trehalose-6-phosphate phosphatase
	Rv2006	otsB1	trehalose-6-phosphate phosphatase
Position: -70 Score: 3.5 Sequence: TGGGGACTAAAGCCTCAT Locus tag: Rv2005c Name: Rv2005c Funciton: universal stress protein Locus tag: Rv2004c Name: Rv2004c Funciton: hypothetical protein Locus tag: Rv2003c Name: Rv2003c Funciton: hypothetical protein
	Rv2005c	Rv2005c	universal stress protein
	Rv2004c	Rv2004c	hypothetical protein
	Rv2003c	Rv2003c	hypothetical protein
Position: -112 Score: 4.6 Sequence: TAAGGACTAACGGCCCTC Position: -91 Score: 4.3 Sequence: TGGGGACCAACGCCCCTG Locus tag: Rv3134c Name: Rv3134c Funciton: universal stress protein Locus tag: Rv3133c Name: dosR Funciton: two component transcriptional regulator, DosR Locus tag: Rv3132c Name: dosS Funciton: two-component sensor histidine kinase, DosS
	Rv3134c	Rv3134c	universal stress protein
	Rv3133c	dosR	two component transcriptional regulator, DosR
	Rv3132c	dosS	two-component sensor histidine kinase, DosS
Position: -133 Score: 4.6 Sequence: TAGGGACAGAAGTCCCCG Position: -76 Score: 4.6 Sequence: TGGGGACCATTGACCCTG Locus tag: Rv2032 Name: acg Funciton: nitroreductase
	Rv2032	acg	nitroreductase
Position: -145 Score: 4.2 Sequence: AAGGGGCGAAAGTCCCTT Position: -63 Score: 4.1 Sequence: TCGTGACCGACGTCCCCA Position: -41 Score: 4.6 Sequence: CAAGGCCGAACGACCCTA Locus tag: Rv1733c Name: Rv1733c Funciton: probable conserved transmembrane protein Locus tag: Rv1732c Name: Rv1732c Funciton: hypothetical protein
	Rv1733c	Rv1733c	probable conserved transmembrane protein
	Rv1732c	Rv1732c	hypothetical protein
Position: -48 Score: 4.6 Sequence: TGGGGACCGAAGTCCCCG Locus tag: Rv1734c Name: Rv1734c Funciton: pyruvate dehydrogenase (E2 component)
	Rv1734c	Rv1734c	pyruvate dehydrogenase (E2 component)
Position: -138 Score: 4.6 Sequence: CAGGGTCAATGGTCCCCA Position: -81 Score: 4.6 Sequence: CGGGGACTTCTGTCCCTA Locus tag: Rv2031c Name: hspX Funciton: heat shock protein HspX_1 Locus tag: Rv2030c Name: Mb2055c Funciton: Erythromycin esterase Locus tag: Rv2029c Name: pfkB Funciton: probable phosphofructokinase Locus tag: Rv2028c Name: usp Funciton: universal stress protein Locus tag: Rv2027c Name: dosT Funciton: two-component system sensor kinase, DosT Locus tag: Rv2026c Name: usp Funciton: universal stress protein Locus tag: Rv2025c Name: Rv2025c Funciton: hypotetical protein
	Rv2031c	hspX	heat shock protein HspX_1
	Rv2030c	Mb2055c	Erythromycin esterase
	Rv2029c	pfkB	probable phosphofructokinase
	Rv2028c	usp	universal stress protein
	Rv2027c	dosT	two-component system sensor kinase, DosT
	Rv2026c	usp	universal stress protein
	Rv2025c	Rv2025c	hypotetical protein
Position: -255 Score: 3.8 Sequence: CGGGGCCGATCGGCATCA Position: -112 Score: 3.8 Sequence: ACGGGTCCATCGACCCGC Position: -89 Score: 4.2 Sequence: ACGGGTCAAACGACCCTA Locus tag: Rv2626c Name: Rv2626c Funciton: putative signal-transduction protein with CBS domains Locus tag: Rv2625c Name: Rv2625c Funciton: conserved transmembrane alanine and leucine rich protein Locus tag: Rv2624c Name: usp Funciton: universal stress protein
	Rv2626c	Rv2626c	putative signal-transduction protein with CBS domains
	Rv2625c	Rv2625c	conserved transmembrane alanine and leucine rich protein
	Rv2624c	usp	universal stress protein
Position: -75 Score: 3.8 Sequence: TAGGGACCATCGCCTCCT Locus tag: Rv1996 Name: Rv1996 Funciton: universal stress protein
	Rv1996	Rv1996	universal stress protein
Position: -155 Score: 4.3 Sequence: TAGGGCATAAAGTCTCTA Position: -122 Score: 4.2 Sequence: TAGGGAACAACGGCCTTC Locus tag: Rv1814 Name: Erg3_1 Funciton: membrane-bound C-5 sterol desaturase Erg3_1
	Rv1814	Erg3_1	membrane-bound C-5 sterol desaturase Erg3_1
Position: -51 Score: 4.2 Sequence: CAGGGACCTAATTCCATA Locus tag: Rv0571c Name: null Funciton: hypothetical protein, , probably phosphoribosyltransferase
	Rv0571c		hypothetical protein, , probably phosphoribosyltransferase
Position: -304 Score: 4.2 Sequence: GAAGGCCGTTGTTCCCTA Position: -271 Score: 4.3 Sequence: TAGAGACTTTATGCCCTA Locus tag: Rv1813c Name: null Funciton: hypothetical protein
	Rv1813c		hypothetical protein
Position: -275 Score: 4.7 Sequence: TAGGGACTTACGTCCCGC Position: -36 Score: 4.2 Sequence: AAGTGACGAAAGACCCCA Locus tag: Rv2628 Name: null Funciton: hypothetical protein
	Rv2628		hypothetical protein
Position: -171 Score: 4.6 Sequence: TAGGGCCTGAAGTCCCGG Position: -109 Score: 4.6 Sequence: TGGGGACTTCCGGCCCTA Locus tag: Rv1737c Name: narK2 Funciton: nitrate/nitrite transporter protein Locus tag: Rv1736c Name: narX Funciton: Probable nitrate reductase NarX
	Rv1737c	narK2	nitrate/nitrite transporter protein
	Rv1736c	narX	Probable nitrate reductase NarX
Position: -195 Score: 4.6 Sequence: TAGGGCCGGAAGTCCCCA Position: -133 Score: 4.6 Sequence: CCGGGACTTCAGGCCCTA Locus tag: Rv1738 Name: null Funciton: hypothetical protein
	Rv1738		hypothetical protein
Position: -332 Score: 4.6 Sequence: CAGGGCCGAAAGTCCCAT Locus tag: Rv0078A Name: null Funciton: hypothetical protein, nucleotidyl transferase of unknown function (DUF1814)
	Rv0078A		hypothetical protein, nucleotidyl transferase of unknown function (DUF1814)
Position: -111 Score: 4.5 Sequence: TGAGGACCTTCGGCCCCA Locus tag: Rv0574c Name: null Funciton: polyglutamate synthase Locus tag: Rv0573c Name: null Funciton: nicotinic acid phosphoribosyltransferase
	Rv0574c		polyglutamate synthase
	Rv0573c		nicotinic acid phosphoribosyltransferase
Position: -76 Score: 4.6 Sequence: TAAGGCCTTTGGTCCTTT Locus tag: Rv2007c Name: fdxA Funciton: 4Fe-4S ferredoxin, iron-sulfur binding protein
	Rv2007c	fdxA	4Fe-4S ferredoxin, iron-sulfur binding protein
Position: -109 Score: 4.3 Sequence: CAGGGCCAAAGGTCCTCC Locus tag: Rv3131 Name: Rv3131 Funciton: nitroreductase
	Rv3131	Rv3131	nitroreductase
Position: -291 Score: 4.2 Sequence: TGGGGTCTTTCGTCACTT Position: -121 Score: 3.7 Sequence: TAGGGCACTTGGGCCACC Position: -52 Score: 4.7 Sequence: GCGGGACGTAAGTCCCTA Locus tag: Rv2627c Name: null Funciton: hypothetical protein
	Rv2627c		hypothetical protein

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of DosR in Mycobacterium tuberculosis H37Rv

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --