Regulon of DosR in Mycobacterium sp. MCS

Properties
Regulator type:	Transcription factor
TF locus tag:	Mmcs_1076, Mmcs_4126
Regulator family:	LuxR
Regulation mode:	activator
Biological process:	Dormancy
Effector:	Oxygen; Carbon monoxide; Nitric oxide
Regulog:	DosR - Actinomycetales
Statistics of regulated genes:
- Genes	49
- Operons	26
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 299 sites [see more]

Member of regulog collections

By TF family - LuxR
By effector - Oxygen
By effector - Carbon monoxide
By effector - Nitric oxide
By pathway - Dormancy

Regulated operons
	Locus Tag	Name	Function
Position: -52 Score: 5.1 Sequence: CAGGGTCCAAGGTCCCTA Locus tag: Mmcs_1102 Name: Rv1996 Funciton: universal stress protein Locus tag: Mmcs_1101 Name: ctpF Funciton: cation-transporting ATPase
	Mmcs_1102	Rv1996	universal stress protein
	Mmcs_1101	ctpF	cation-transporting ATPase
Position: -84 Score: 5.1 Sequence: AAGGGACCAAAGGCCCTA Locus tag: Mmcs_3621 Name: usp Funciton: universal stress protein
	Mmcs_3621	usp	universal stress protein
Position: -52 Score: 4.7 Sequence: TCGGGACCAATGGCCCTG Locus tag: Mmcs_3541 Name: MSMEG_5242 Funciton: acyltransferase, ws/dgat/mgat subfamily protein
	Mmcs_3541	MSMEG_5242	acyltransferase, ws/dgat/mgat subfamily protein
Position: -128 Score: 4.7 Sequence: ACGGGCCGATGGTCCCTA Locus tag: Mmcs_1078 Name: Rv3131 Funciton: nitroreductase
	Mmcs_1078	Rv3131	nitroreductase
Position: -76 Score: 4.6 Sequence: TCGGGACCTTCGTCTCTG Locus tag: Mmcs_1107 Name: Rv3131 Funciton: nitroreductase
	Mmcs_1107	Rv3131	nitroreductase
Position: -51 Score: 4.3 Sequence: TCGGGCCTTTGTGCCCTA Locus tag: Mmcs_4124 Name: Rv3131 Funciton: nitroreductase
	Mmcs_4124	Rv3131	nitroreductase
Position: -52 Score: 4.5 Sequence: TGAGGACTTTCGGCCCCA Locus tag: Mmcs_2719 Name: fdxA Funciton: 4Fe-4S ferredoxin, iron-sulfur binding protein
	Mmcs_2719	fdxA	4Fe-4S ferredoxin, iron-sulfur binding protein
Position: -79 Score: 4.1 Sequence: GCGGGTCGAACGTCCCGA Position: -47 Score: 4.5 Sequence: TGGGGTCTTTCGACCCTG Locus tag: Mmcs_1083 Name: MAV_4110 Funciton: hypothetical protein
	Mmcs_1083	MAV_4110	hypothetical protein
Position: -148 Score: 4.8 Sequence: CCGGGACCAACGGCCCTG Locus tag: Mmcs_1097 Name: Rv1996 Funciton: universal stress protein Locus tag: Mmcs_1098 Name: null Funciton: hypothetical protein Locus tag: Mmcs_1099 Name: Mmcs_1099 Funciton: magnesium and cobalt efflux protein CorC Locus tag: Mmcs_1100 Name: merR2 Funciton: HAD-superfamily hydrolase subfamily IIB
	Mmcs_1097	Rv1996	universal stress protein
	Mmcs_1098		hypothetical protein
	Mmcs_1099	Mmcs_1099	magnesium and cobalt efflux protein CorC
	Mmcs_1100	merR2	HAD-superfamily hydrolase subfamily IIB
Position: -103 Score: 4.2 Sequence: TAGAGACGAAAGTCACCA Position: -74 Score: 4.1 Sequence: AGGAGCCTTAAGTCCCCT Locus tag: Mmcs_1088 Name: null Funciton: hypothetical protein
	Mmcs_1088		hypothetical protein
Position: -85 Score: 4.5 Sequence: GAGTGACCAAAGTCCCTG Locus tag: Mmcs_3036 Name: null Funciton: cytochrome bd ubiquinol oxidase subunit 1 Locus tag: Mmcs_3037 Name: null Funciton: cytochrome bd ubiquinol oxidase subunit II Locus tag: Mmcs_3038 Name: null Funciton: transport ATP-binding protein CydD Locus tag: Mmcs_3039 Name: null Funciton: transport ATP-binding protein CydC
	Mmcs_3036		cytochrome bd ubiquinol oxidase subunit 1
	Mmcs_3037		cytochrome bd ubiquinol oxidase subunit II
	Mmcs_3038		transport ATP-binding protein CydD
	Mmcs_3039		transport ATP-binding protein CydC
Position: -57 Score: 4.3 Sequence: AAGGGTCCAAATGCCCTG Locus tag: Mmcs_3414 Name: null Funciton: 3-oxoacyl-(acyl-carrier protein) synthase Locus tag: Mmcs_3413 Name: null Funciton: 3-oxoacyl-[acyl-carrier-protein] synthase III
	Mmcs_3414		3-oxoacyl-(acyl-carrier protein) synthase
	Mmcs_3413		3-oxoacyl-[acyl-carrier-protein] synthase III
Position: -72 Score: 4.6 Sequence: CAGGGCCGTTGGTCTCTT Position: -18 Score: 4.4 Sequence: TCGGGACTTCAGACCCTG Locus tag: Mmcs_3409 Name: DGAT Funciton: wax-dgat acyltransferase Locus tag: Mmcs_3410 Name: MAV_2505 Funciton: nitroreductase Locus tag: Mmcs_3411 Name: usp Funciton: universal stress protein Locus tag: Mmcs_3412 Name: pfkB Funciton: probable phosphofructokinase
	Mmcs_3409	DGAT	wax-dgat acyltransferase
	Mmcs_3410	MAV_2505	nitroreductase
	Mmcs_3411	usp	universal stress protein
	Mmcs_3412	pfkB	probable phosphofructokinase
Position: -76 Score: 3.6 Sequence: GTGTGACTTCCGACCCTG Locus tag: Mmcs_3406 Name: null Funciton: pyruvate dikinase Locus tag: Mmcs_3407 Name: otsB1 Funciton: trehalose-6-phosphate phosphatase
	Mmcs_3406		pyruvate dikinase
	Mmcs_3407	otsB1	trehalose-6-phosphate phosphatase
Position: -40 Score: 4.1 Sequence: AGGTGACCAATGACCCTG Locus tag: Mmcs_1095 Name: MSMEG_3935 Funciton: hypothetical protein Locus tag: Mmcs_1096 Name: adhA Funciton: alcohol dehydrogenase
	Mmcs_1095	MSMEG_3935	hypothetical protein
	Mmcs_1096	adhA	alcohol dehydrogenase
Position: -102 Score: 3.7 Sequence: CATGGTCTTTGGTCCTCC Locus tag: Mmcs_1104 Name: usp Funciton: universal stress protein Locus tag: Mmcs_1103 Name: Mmcs_1103 Funciton: MgtE integral membrane region
	Mmcs_1104	usp	universal stress protein
	Mmcs_1103	Mmcs_1103	MgtE integral membrane region
Position: -51 Score: 4.6 Sequence: ACAGGACCTAAGGCCCTA Locus tag: Mmcs_4128 Name: acg Funciton: nitroreductase Locus tag: Mmcs_4127 Name: usp Funciton: universal stress protein Locus tag: Mmcs_4126 Name: dosR Funciton: two component transcriptional regulator, DosR Locus tag: Mmcs_4125 Name: dosT Funciton: two-component system sensor kinase, DosT
	Mmcs_4128	acg	nitroreductase
	Mmcs_4127	usp	universal stress protein
	Mmcs_4126	dosR	two component transcriptional regulator, DosR
	Mmcs_4125	dosT	two-component system sensor kinase, DosT
Position: -107 Score: 4.4 Sequence: CGGGGCCATTGGTCCTCA Locus tag: Mmcs_1075 Name: acg Funciton: nitroreductase Locus tag: Mmcs_1076 Name: dosR Funciton: two component transcriptional regulator, DosR Locus tag: Mmcs_1077 Name: dosS Funciton: two-component sensor histidine kinase, DosS
	Mmcs_1075	acg	nitroreductase
	Mmcs_1076	dosR	two component transcriptional regulator, DosR
	Mmcs_1077	dosS	two-component sensor histidine kinase, DosS
Position: -37 Score: 3.5 Sequence: AAGAGTCTTTGGTCACAC Locus tag: Mmcs_1074 Name: Rv2004c Funciton: hypothetical protein Locus tag: Mmcs_1073 Name: Mmcs_1073 Funciton: alcohol dehydrogenase GroES-like protein Locus tag: Mmcs_1072 Name: usp Funciton: universal stress protein
	Mmcs_1074	Rv2004c	hypothetical protein
	Mmcs_1073	Mmcs_1073	alcohol dehydrogenase GroES-like protein
	Mmcs_1072	usp	universal stress protein
Position: -52 Score: 4.4 Sequence: GCGGGACCTTCGACCCTG Locus tag: Mmcs_1080 Name: Mmcs_1080 Funciton: hypothetical protein Locus tag: Mmcs_1079 Name: MMAR_3503 Funciton: metal cation transporter p-type ATPase
	Mmcs_1080	Mmcs_1080	hypothetical protein
	Mmcs_1079	MMAR_3503	metal cation transporter p-type ATPase
Position: -81 Score: 4.7 Sequence: TAGGGCCCATTGTCCCCT Position: -44 Score: 3.8 Sequence: GGATGACTTCCGTCCCTA Locus tag: Mmcs_1081 Name: Mb2055c Funciton: Erythromycin esterase
	Mmcs_1081	Mb2055c	Erythromycin esterase
Position: -107 Score: 4.1 Sequence: AGGGGACTTAAGGCTCCT Position: -78 Score: 4.2 Sequence: TGGTGACTTTCGTCTCTA Locus tag: Mmcs_1089 Name: MAV_3502 Funciton: hypothetical protein
	Mmcs_1089	MAV_3502	hypothetical protein
Position: -51 Score: 3.8 Sequence: ACCAGACCAACGGCCCTA Locus tag: Mmcs_4257 Name: null Funciton: hypothetical protein Locus tag: Mmcs_4258 Name: DGAT Funciton: wax-dgat acyltransferase
	Mmcs_4257		hypothetical protein
	Mmcs_4258	DGAT	wax-dgat acyltransferase
Position: -185 Score: 3.9 Sequence: TACGGGCCAAAGTCCCTT Position: -123 Score: 5 Sequence: CAGGGACTTTCGGCCCTG Locus tag: Mmcs_1087 Name: usp Funciton: universal stress protein
	Mmcs_1087	usp	universal stress protein
Position: -89 Score: 3.8 Sequence: TAGGGACGGAAGTCATCC Position: -52 Score: 4.7 Sequence: AGGGGACAATGGGCCCTA Locus tag: Mmcs_1082 Name: null Funciton: hypothetical protein
	Mmcs_1082		hypothetical protein
Position: -77 Score: 4.4 Sequence: CAGGGTCTGAAGTCCCGA Position: -23 Score: 4.6 Sequence: AAGAGACCAACGGCCCTG Locus tag: Mmcs_3408 Name: DGAT Funciton: wax-dgat acyltransferase
	Mmcs_3408	DGAT	wax-dgat acyltransferase

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of DosR in Mycobacterium sp. MCS

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --