Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of DosR in Mycobacterium smegmatis str. MC2 155

Properties
Regulator type: Transcription factor
TF locus tag: MSMEG_5244, MSMEG_3944
Regulator family: LuxR
Regulation mode: activator
Biological process: Dormancy
Effector: Oxygen; Carbon monoxide; Nitric oxide
Regulog: DosR - Actinomycetales
Statistics of regulated genes:
- Genes 33
- Operons 16
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 299 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -51
Score: 4.6
Sequence: TGAGGACCAAAGACCCTA
Locus tag: MSMEG_5246
Name: acg
Funciton: nitroreductase
Locus tag: MSMEG_5245
Name: usp
Funciton: universal stress protein
Locus tag: MSMEG_5244
Name: dosR
Funciton: two component transcriptional regulator, DosR
Locus tag: MSMEG_5243
Name: MAV_4110
Funciton: hypothetical protein
Locus tag: MSMEG_5242
Name: MSMEG_5242
Funciton: acyltransferase, ws/dgat/mgat subfamily protein
Locus tag: MSMEG_5241
Name: dosT
Funciton: two-component system sensor kinase, DosT
acg
nitroreductase
usp
universal stress protein
dosR
two component transcriptional regulator, DosR
MAV_4110
hypothetical protein
MSMEG_5242
acyltransferase, ws/dgat/mgat subfamily protein
dosT
two-component system sensor kinase, DosT

Position: -81
Score: 4.3
Sequence: AGGTGACTTTCGGCCCTG
Locus tag: MSMEG_3935
Name: null
Funciton: hypothetical protein
Locus tag: MSMEG_3933
Name: DGAT
Funciton: wax-dgat acyltransferase
hypothetical protein
DGAT
wax-dgat acyltransferase

Position: -81
Score: 4.4
Sequence: CAGGGCCGTTGGTCACCG
Locus tag: MSMEG_3954
Name: otsB1
Funciton: trehalose-6-phosphate phosphatase
otsB1
trehalose-6-phosphate phosphatase

Position: -60
Score: 3.6
Sequence: ATGGGACTTCTGCCCCTG
Locus tag: MSMEG_3948
Name: DGAT
Funciton: wax-dgat acyltransferase
DGAT
wax-dgat acyltransferase

Position: -125
Score: 4.5
Sequence: CAGGGTCCTACGGCCCCC
Position: -104
Score: 4.8
Sequence: TGAGGACCATAGTCCCTG
Locus tag: MSMEG_3943
Name: acg
Funciton: nitroreductase
Locus tag: MSMEG_3944
Name: dosR
Funciton: two component transcriptional regulator, DosR
acg
nitroreductase
dosR
two component transcriptional regulator, DosR

Position: -51
Score: 3.7
Sequence: CCAGGGCGTAAGGCCCGA
Locus tag: MSMEG_3616
Name: null
Funciton: integral membrane protein
Locus tag: MSMEG_3615
Name: adhA
Funciton: alcohol dehydrogenase
integral membrane protein
adhA
alcohol dehydrogenase

Position: -51
Score: 4.4
Sequence: CGGTGACCAACGGCCCTG
Locus tag: MSMEG_3953
Name: null
Funciton: 3-oxoacyl-(acyl-carrier protein) synthase
Locus tag: MSMEG_3951
Name: null
Funciton: 3-oxoacyl-[acyl-carrier-protein] synthase III
3-oxoacyl-(acyl-carrier protein) synthase
3-oxoacyl-[acyl-carrier-protein] synthase III

Position: -150
Score: 4.1
Sequence: AAGGGACCGAAGTCCACG
Position: -79
Score: 4.3
Sequence: CCGGGACTTAGGTCACCA
Locus tag: MSMEG_3939
Name: usp
Funciton: universal stress protein
usp
universal stress protein

Position: -145
Score: 4.4
Sequence: TAGGGACGAAAGTCTCAA
Position: -51
Score: 3.6
Sequence: GTGCGACTTCGGTCCCTA
Locus tag: MSMEG_3947
Name: pfkB
Funciton: probable phosphofructokinase
pfkB
probable phosphofructokinase

Position: -324
Score: 4
Sequence: GAAGGCCTTAGGTCACCT
Position: -105
Score: 3.9
Sequence: CAGGGACGAAAGTTCGTG
Position: -84
Score: 4.6
Sequence: ACGGGACTTCGGTCCCTA
Locus tag: MSMEG_3932
Name: hspX
Funciton: heat shock protein HspX_1
Locus tag: MSMEG_3931
Name: MSMEG_3931
Funciton: 4Fe-4S ferredoxin, iron-sulfur binding protein
Locus tag: MSMEG_3930
Name: null
Funciton: flavodoxin oxidoreductase
Locus tag: MSMEG_3929
Name: null
Funciton: NADH ubiquinone oxidoreductase, 20 kDa subunit
Locus tag: MSMEG_3928
Name: null
Funciton: oxidoreductase
Locus tag: MSMEG_3927
Name: null
Funciton: hypothetical protein
Locus tag: MSMEG_3926
Name: MSMEG_3926
Funciton: cation transportind ATPase
hspX
heat shock protein HspX_1
MSMEG_3931
4Fe-4S ferredoxin, iron-sulfur binding protein
flavodoxin oxidoreductase
NADH ubiquinone oxidoreductase, 20 kDa subunit
oxidoreductase
hypothetical protein
MSMEG_3926
cation transportind ATPase

Position: -73
Score: 4.8
Sequence: CAGGGACTATGGTCCTCA
Position: -52
Score: 4.5
Sequence: GGGGGCCGTAGGACCCTG
Locus tag: MSMEG_3942
Name: Rv2004c
Funciton: hypothetical protein
Rv2004c
hypothetical protein

Position: -80
Score: 4.7
Sequence: AAAGGACCAAAGGCCCTT
Locus tag: MSMEG_3950
Name: usp
Funciton: universal stress protein
Locus tag: MSMEG_3952
Name: null
Funciton: hypothetical protein
usp
universal stress protein
hypothetical protein

Position: -88
Score: 4.4
Sequence: TTGAGACTTTCGTCCCTA
Locus tag: MSMEG_3949
Name: MAV_3502
Funciton: hypothetical protein
MAV_3502
hypothetical protein

Position: -51
Score: 4.4
Sequence: TAGGGACTTTCGGCCATT
Locus tag: MSMEG_5733
Name: usp
Funciton: universal stress protein protein
usp
universal stress protein protein

Position: -79
Score: 4.9
Sequence: TCGGGACTTTCGTCCCTA
Locus tag: MSMEG_3940
Name: MSMEG_3940
Funciton: universal stress protein family protein
MSMEG_3940
universal stress protein family protein

Position: -117
Score: 3.6
Sequence: CAGGGGCAGAAGTCCCAT
Locus tag: MSMEG_3946
Name: null
Funciton: probable conserved transmembrane protein
Locus tag: MSMEG_3945
Name: Rv1996
Funciton: universal stress protein
probable conserved transmembrane protein
Rv1996
universal stress protein
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