Regulon of DosR in Mycobacterium marinum M

Properties
Regulator type:	Transcription factor
TF locus tag:	MMAR_3480, MMAR_1516
Regulator family:	LuxR
Regulation mode:	activator
Biological process:	Dormancy
Effector:	Oxygen; Carbon monoxide; Nitric oxide
Regulog:	DosR - Actinomycetales
Statistics of regulated genes:
- Genes	66
- Operons	34
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 299 sites [see more]

Member of regulog collections

By TF family - LuxR
By effector - Oxygen
By effector - Carbon monoxide
By effector - Nitric oxide
By pathway - Dormancy

Regulated operons
	Locus Tag	Name	Function
Position: -104 Score: 3.8 Sequence: GAGTGACAAACGGCTCTG Locus tag: MMAR_2077 Name: Rv2623 usp Funciton: universal stress protein
	MMAR_2077	Rv2623 usp	universal stress protein
Position: -74 Score: 4.6 Sequence: AAAGGTCTTTGGTCCCTG Locus tag: MMAR_2994 Name: fdxA Funciton: 4Fe-4S ferredoxin, iron-sulfur binding protein Locus tag: MMAR_2993 Name: Rv2005c Funciton: universal stress protein
	MMAR_2994	fdxA	4Fe-4S ferredoxin, iron-sulfur binding protein
	MMAR_2993	Rv2005c	universal stress protein
Position: -102 Score: 4.6 Sequence: TAGGGACCAATGGCACTG Position: -81 Score: 3.9 Sequence: TCGGGACCAACGCCTCTG Locus tag: MMAR_1515 Name: Rv3134c Funciton: universal stress protein Locus tag: MMAR_1516 Name: dosR Funciton: two component transcriptional regulator, DosR Locus tag: MMAR_1517 Name: dosS Funciton: two-component sensor histidine kinase, DosS
	MMAR_1515	Rv3134c	universal stress protein
	MMAR_1516	dosR	two component transcriptional regulator, DosR
	MMAR_1517	dosS	two-component sensor histidine kinase, DosS
Position: -74 Score: 4.7 Sequence: GAAGGACCAACGGCCCTG Locus tag: MMAR_3475 Name: nitroreductase Funciton: nitroreductase Locus tag: MMAR_3474 Name: null Funciton: 3-oxoacyl-(acyl-carrier protein) synthase Locus tag: MMAR_3473 Name: null Funciton: 3-oxoacyl-[acyl-carrier-protein] synthase III
	MMAR_3475	nitroreductase	nitroreductase
	MMAR_3474		3-oxoacyl-(acyl-carrier protein) synthase
	MMAR_3473		3-oxoacyl-[acyl-carrier-protein] synthase III
Position: -289 Score: 3.4 Sequence: CCGGGACCGCTGGCCTGC Position: -214 Score: 4.6 Sequence: CAGGGCCGTTTGGCCCCG Locus tag: MMAR_3477 Name: MAV_2507 Funciton: universal stress protein Locus tag: MMAR_3476 Name: Rv2004c Funciton: hypothetical protein
	MMAR_3477	MAV_2507	universal stress protein
	MMAR_3476	Rv2004c	hypothetical protein
Position: -70 Score: 4.1 Sequence: CGGGGGCCAAAGGCCCTT Locus tag: MMAR_3487 Name: MAV_2505 Funciton: nitroreductase
	MMAR_3487	MAV_2505	nitroreductase
Position: -100 Score: 3.7 Sequence: AATGGCACAAAGTCCCTC Locus tag: MMAR_3502 Name: Rv3131 Funciton: nitroreductase Locus tag: MMAR_3501 Name: Rv1733c Funciton: probable conserved transmembrane protein Locus tag: MMAR_3500 Name: null Funciton: ferredoxin Locus tag: MMAR_3499 Name: null Funciton: flavodoxin oxidoreductase Locus tag: MMAR_3498 Name: null Funciton: NADH ubiquinone oxidoreductase, 20 kDa subunit Locus tag: MMAR_3497 Name: null Funciton: oxidoreductase Locus tag: MMAR_3496 Name: null Funciton: hypothetical protein
	MMAR_3502	Rv3131	nitroreductase
	MMAR_3501	Rv1733c	probable conserved transmembrane protein
	MMAR_3500		ferredoxin
	MMAR_3499		flavodoxin oxidoreductase
	MMAR_3498		NADH ubiquinone oxidoreductase, 20 kDa subunit
	MMAR_3497		oxidoreductase
	MMAR_3496		hypothetical protein
Position: -149 Score: 3.8 Sequence: CGAAGTCCTAAGGCCCGG Position: -126 Score: 4 Sequence: CTGGGTATTACGGCCCTA Locus tag: MMAR_3503 Name: MMAR_3503 Funciton: metal cation transporter p-type ATPase
	MMAR_3503	MMAR_3503	metal cation transporter p-type ATPase
Position: -68 Score: 4.8 Sequence: CAAGGACTTTCGGCCCTA Locus tag: MMAR_3705 Name: null Funciton: hypothetical protein Locus tag: MMAR_3704 Name: desA Funciton: fatty acid desaturase
	MMAR_3705		hypothetical protein
	MMAR_3704	desA	fatty acid desaturase
Position: -219 Score: 4.7 Sequence: TAGGGTCTTACGTCCCGA Position: -153 Score: 4.1 Sequence: GGATGACTTTGGGCCCTA Locus tag: MMAR_2071 Name: fadD11_1 Funciton: long-chain-fatty-acid-CoA ligase, FadD11_1 Locus tag: MMAR_2070 Name: null Funciton: hypothetical protein, eRF1_3 family
	MMAR_2071	fadD11_1	long-chain-fatty-acid-CoA ligase, FadD11_1
	MMAR_2070		hypothetical protein, eRF1_3 family
Position: -125 Score: 3.5 Sequence: GTGGGACGAATGGCTCCC Position: -102 Score: 4 Sequence: ATGGGCCTAAAGACCCGT Locus tag: MMAR_3392 Name: null Funciton: hypothetical protein
	MMAR_3392		hypothetical protein
Position: -94 Score: 4.6 Sequence: CCGGGCCTTTTGGCCCTG Locus tag: MMAR_2691 Name: Erg3_1 Funciton: membrane-bound C-5 sterol desaturase Erg3_1
	MMAR_2691	Erg3_1	membrane-bound C-5 sterol desaturase Erg3_1
Position: -54 Score: 4 Sequence: GCGTGACATTCGGCCCTG Locus tag: MMAR_2069 Name: null Funciton: hypothetical protein, , probably phosphoribosyltransferase
	MMAR_2069		hypothetical protein, , probably phosphoribosyltransferase
Position: -419 Score: 4.8 Sequence: TAGGGCCGATAGTCCCCG Position: -260 Score: 4.1 Sequence: CATTGACATTGGTCCCTA Locus tag: MMAR_1426 Name: null Funciton: hypothetical protein
	MMAR_1426		hypothetical protein
Position: -79 Score: 4.1 Sequence: TGAGGACCAAAGTCATTG Locus tag: MMAR_2649 Name: DGAT Funciton: wax-dgat acyltransferase
	MMAR_2649	DGAT	wax-dgat acyltransferase
Position: -113 Score: 3.7 Sequence: AAGGGACCAACGCCTCCT Locus tag: MMAR_5410 Name: Rv1996 Funciton: universal stress protein
	MMAR_5410	Rv1996	universal stress protein
Position: -177 Score: 4 Sequence: TAGTGACGAAAGACCCGC Locus tag: MMAR_1228 Name: ctpH_1 Funciton: metal cation transporting ATPase, P-type ATPase superfamily
	MMAR_1228	ctpH_1	metal cation transporting ATPase, P-type ATPase superfamily
Position: -93 Score: 4.8 Sequence: GAGGGACCTTTGGCCCTG Locus tag: MMAR_1519 Name: DGAT Funciton: wax-dgat acyltransferase Locus tag: MMAR_1520 Name: null Funciton: hypothetical protein
	MMAR_1519	DGAT	wax-dgat acyltransferase
	MMAR_1520		hypothetical protein
Position: -266 Score: 4.1 Sequence: AAGGGCCTTTGGCCCCCG Position: -245 Score: 3.6 Sequence: CGACGACATAGGGCCCCG Locus tag: MMAR_3488 Name: acs_1 Funciton: acetyl-coenzyme A synthetase Acs_1 Locus tag: MMAR_3489 Name: null Funciton: pyruvate dehydrogenase E1 component (alpha subunit) Locus tag: MMAR_3490 Name: null Funciton: pyruvate dehydrogenase E1 component (beta subunit) Locus tag: MMAR_3491 Name: null Funciton: pyruvate dehydrogenase (E2 component) Locus tag: MMAR_3492 Name: MMAR_3492 Funciton: hypothetical protein Locus tag: MMAR_3493 Name: MAV_4110 Funciton: hypothetical protein Locus tag: MMAR_3494 Name: null Funciton: PE-PGRS family protein
	MMAR_3488	acs_1	acetyl-coenzyme A synthetase Acs_1
	MMAR_3489		pyruvate dehydrogenase E1 component (alpha subunit)
	MMAR_3490		pyruvate dehydrogenase E1 component (beta subunit)
	MMAR_3491		pyruvate dehydrogenase (E2 component)
	MMAR_3492	MMAR_3492	hypothetical protein
	MMAR_3493	MAV_4110	hypothetical protein
	MMAR_3494		PE-PGRS family protein
Position: -101 Score: 3.8 Sequence: GCGGGTCGAAAGGCCCAT Locus tag: MMAR_5272 Name: acrA1_1 Funciton: multi-functional enzyme with acyl-CoA-reductase activity AcrA1_1 Locus tag: MMAR_5271 Name: DGAT Funciton: wax-dgat acyltransferase
	MMAR_5272	acrA1_1	multi-functional enzyme with acyl-CoA-reductase activity AcrA1_1
	MMAR_5271	DGAT	wax-dgat acyltransferase
Position: -158 Score: 3.7 Sequence: TGAGGCCGTACTGCCCCT Locus tag: MMAR_2738 Name: null Funciton: hypothetical protein Locus tag: MMAR_2739 Name: adhA Funciton: alcohol dehydrogenase
	MMAR_2738		hypothetical protein
	MMAR_2739	adhA	alcohol dehydrogenase
Position: -119 Score: 4.1 Sequence: CCGGGACTTTTGTCACCA Locus tag: MMAR_2257 Name: otsB1 Funciton: trehalose-6-phosphate phosphatase
	MMAR_2257	otsB1	trehalose-6-phosphate phosphatase
Position: -52 Score: 4.5 Sequence: CGAGGACCTTTGGCCCTG Locus tag: MMAR_0944 Name: MSMEG_3935 Funciton: hypothetical protein
	MMAR_0944	MSMEG_3935	hypothetical protein
Position: -59 Score: 3.9 Sequence: GAATGACGAATGACCCTA Locus tag: MMAR_1522 Name: acg Funciton: nitroreductase
	MMAR_1522	acg	nitroreductase
Position: -146 Score: 3.6 Sequence: CAGGGACTTACGGCTGGC Position: -123 Score: 4.7 Sequence: AAGGGCCCTTAGGCCCTC Locus tag: MMAR_3403 Name: DGAT Funciton: wax-dgat acyltransferase
	MMAR_3403	DGAT	wax-dgat acyltransferase
Position: -138 Score: 4.2 Sequence: TGGGGTCCATGGACTCTG Locus tag: MMAR_2995 Name: usp Funciton: universal stress protein
	MMAR_2995	usp	universal stress protein
Position: -75 Score: 4.5 Sequence: CAGGGTCAGAAGTCCCTA Locus tag: MMAR_3407 Name: gltD Funciton: NADH-dependent glutamate synthase (small subunit) GltD Locus tag: MMAR_3408 Name: null Funciton: Pyruvate:ferredoxin (flavodoxin) oxidoreductase Locus tag: MMAR_3409 Name: null Funciton: dihydroorotate dehydrogenase Locus tag: MMAR_3410 Name: null Funciton: pyruvate dikinase
	MMAR_3407	gltD	NADH-dependent glutamate synthase (small subunit) GltD
	MMAR_3408		Pyruvate:ferredoxin (flavodoxin) oxidoreductase
	MMAR_3409		dihydroorotate dehydrogenase
	MMAR_3410		pyruvate dikinase
Position: -116 Score: 4.8 Sequence: CAGGGCCAAAGGTCCCTC Locus tag: MMAR_1518 Name: Rv3131 Funciton: nitroreductase
	MMAR_1518	Rv3131	nitroreductase
Position: -87 Score: 4.7 Sequence: CGGGGACTTCCGTCCCTA Locus tag: MMAR_3484 Name: hspX Funciton: heat shock protein HspX_1 Locus tag: MMAR_3483 Name: Mb2055c Funciton: Erythromycin esterase Locus tag: MMAR_3482 Name: pfkB Funciton: probable phosphofructokinase
	MMAR_3484	hspX	heat shock protein HspX_1
	MMAR_3483	Mb2055c	Erythromycin esterase
	MMAR_3482	pfkB	probable phosphofructokinase
Position: -52 Score: 4.5 Sequence: TAGGGACTTCTGACCCTG Locus tag: MMAR_3406 Name: DGAT Funciton: wax-dgat acyltransferase
	MMAR_3406	DGAT	wax-dgat acyltransferase
Position: -119 Score: 4.1 Sequence: TAGGGCCCAAAGTCATCC Position: -53 Score: 4.7 Sequence: TCGGGACGTAAGACCCTA Locus tag: MMAR_2072 Name: null Funciton: hypothetical protein Locus tag: MMAR_2073 Name: DGAT Funciton: wax-dgat acyltransferase Locus tag: MMAR_2074 Name: null Funciton: hypothetical protein Locus tag: MMAR_2075 Name: Rv2625c Funciton: conserved transmembrane alanine and leucine rich protein Locus tag: MMAR_2076 Name: usp Funciton: universal stress protein
	MMAR_2072		hypothetical protein
	MMAR_2073	DGAT	wax-dgat acyltransferase
	MMAR_2074		hypothetical protein
	MMAR_2075	Rv2625c	conserved transmembrane alanine and leucine rich protein
	MMAR_2076	usp	universal stress protein
Position: -94 Score: 4.3 Sequence: AGGTGACTTACGGCCCTA Locus tag: MMAR_3486 Name: MAV_3502 Funciton: hypothetical protein
	MMAR_3486	MAV_3502	hypothetical protein
Position: -106 Score: 4.6 Sequence: CGGGGCCAAACGGCCCTG Position: -31 Score: 3.4 Sequence: GCAGGCCAGCGGTCCCGG Locus tag: MMAR_3478 Name: usp Funciton: universal stress protein
	MMAR_3478	usp	universal stress protein
Position: -79 Score: 3.8 Sequence: AGCGGTCCAACGGCCCTC Locus tag: MMAR_3481 Name: usp Funciton: universal stress protein
	MMAR_3481	usp	universal stress protein

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of DosR in Mycobacterium marinum M

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --