Regulon of DosR in Mycobacterium bovis AF2122/97

Properties
Regulator type:	Transcription factor
TF locus tag:	Mb3157c
Regulator family:	LuxR
Regulation mode:	activator
Biological process:	Dormancy
Effector:	Oxygen; Carbon monoxide; Nitric oxide
Regulog:	DosR - Actinomycetales
Statistics of regulated genes:
- Genes	44
- Operons	25
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 299 sites [see more]

Member of regulog collections

By TF family - LuxR
By effector - Oxygen
By effector - Carbon monoxide
By effector - Nitric oxide
By pathway - Dormancy

Regulated operons
	Locus Tag	Name	Function
Position: -130 Score: 3.5 Sequence: TGAGGACCTAAGCCCGTT Locus tag: Mb2656 Name: Rv2623 usp Funciton: universal stress protein
	Mb2656	Rv2623 usp	universal stress protein
Position: -111 Score: 4.2 Sequence: CTGGACCGTAGGTCCCTG Position: -89 Score: 4 Sequence: GGATGACTTACGGCCCTG Locus tag: Mb2020 Name: ctpF Funciton: cation-transporting ATPase
	Mb2020	ctpF	cation-transporting ATPase
Position: -75 Score: 3.8 Sequence: TAGGGACCATCGCCTCCT Locus tag: Mb2019 Name: Rv1996 Funciton: universal stress protein
	Mb2019	Rv1996	universal stress protein
Position: -88 Score: 4.6 Sequence: ATGGGACTTTCGGCCCTG Locus tag: Mb0082 Name: null Funciton: hypothetical protein Locus tag: Mb0083 Name: null Funciton: hypothetical protein
	Mb0082		hypothetical protein
	Mb0083		hypothetical protein
Position: -300 Score: 4.2 Sequence: GGATGACTTTGGTCCCTA Locus tag: Mb2662 Name: null Funciton: hypothetical protein, eRF1_3 family Locus tag: Mb2663 Name: null Funciton: hypothetical protein, archease protein family Locus tag: Mb2664 Name: null Funciton: hypothetical protein
	Mb2662		hypothetical protein, eRF1_3 family
	Mb2663		hypothetical protein, archease protein family
	Mb2664		hypothetical protein
Position: -155 Score: 4.3 Sequence: TAGGGCATAAAGTCTCTA Position: -122 Score: 4.2 Sequence: TAGGGAACAACGGCCTTC Locus tag: Mb1844 Name: Erg3_1 Funciton: membrane-bound C-5 sterol desaturase Erg3_1
	Mb1844	Erg3_1	membrane-bound C-5 sterol desaturase Erg3_1
Position: -51 Score: 4.2 Sequence: CAGGGACCTAATTCCATA Locus tag: Mb0586c Name: null Funciton: hypothetical protein, , probably phosphoribosyltransferase
	Mb0586c		hypothetical protein, , probably phosphoribosyltransferase
Position: -304 Score: 4.2 Sequence: GAAGGCCGTTGTTCCCTA Position: -271 Score: 4.3 Sequence: TAGAGACTTTATGCCCTA Locus tag: Mb1843c Name: null Funciton: hypothetical protein
	Mb1843c		hypothetical protein
Position: -275 Score: 4.7 Sequence: TAGGGACTTACGTCCCGC Position: -36 Score: 4.2 Sequence: AAGTGACGAAAGACCCCA Locus tag: Mb2661 Name: null Funciton: hypothetical protein
	Mb2661		hypothetical protein
Position: -171 Score: 4.6 Sequence: TAGGGCCTGAAGTCCCGG Position: -109 Score: 4.6 Sequence: TGGGGACTTCCGGCCCTA Locus tag: Mb1766c Name: narK2 Funciton: nitrate/nitrite transporter protein Locus tag: Mb1765c Name: narX Funciton: Probable nitrate reductase NarX
	Mb1766c	narK2	nitrate/nitrite transporter protein
	Mb1765c	narX	Probable nitrate reductase NarX
Position: -195 Score: 4.6 Sequence: TAGGGCCGGAAGTCCCCA Position: -133 Score: 4.6 Sequence: CCGGGACTTCAGGCCCTA Locus tag: Mb1767 Name: null Funciton: hypothetical protein
	Mb1767		hypothetical protein
Position: -332 Score: 4.6 Sequence: CAGGGCCGAAAGTCCCAT Locus tag: Mb0081c Name: null Funciton: hypothetical protein, nucleotidyl transferase of unknown function (DUF1814)
	Mb0081c		hypothetical protein, nucleotidyl transferase of unknown function (DUF1814)
Position: -111 Score: 4.5 Sequence: TGAGGACCTTCGGCCCCA Locus tag: Mb0589c Name: null Funciton: polyglutamate synthase Locus tag: Mb0588c Name: null Funciton: nicotinic acid phosphoribosyltransferase
	Mb0589c		polyglutamate synthase
	Mb0588c		nicotinic acid phosphoribosyltransferase
Position: -66 Score: 3.5 Sequence: ATGAGGCTTTAGTCCCCA Locus tag: Mb2029 Name: otsB1 Funciton: trehalose-6-phosphate phosphatase
	Mb2029	otsB1	trehalose-6-phosphate phosphatase
Position: -70 Score: 3.5 Sequence: TGGGGACTAAAGCCTCAT Locus tag: Mb2028c Name: Rv2005c Funciton: universal stress protein Locus tag: Mb2027c Name: Rv2004c Funciton: hypothetical protein Locus tag: Mb2026c Name: Rv2003c Funciton: hypothetical protein
	Mb2028c	Rv2005c	universal stress protein
	Mb2027c	Rv2004c	hypothetical protein
	Mb2026c	Rv2003c	hypothetical protein
Position: -112 Score: 4.6 Sequence: TAAGGACTAACGGCCCTC Position: -91 Score: 4.3 Sequence: TGGGGACCAACGCCCCTG Locus tag: Mb3158c Name: Rv3134c Funciton: universal stress protein Locus tag: Mb3157c Name: dosR Funciton: two component transcriptional regulator, DosR Locus tag: Mb3156c Name: dosS Funciton: two-component sensor histidine kinase, DosS
	Mb3158c	Rv3134c	universal stress protein
	Mb3157c	dosR	two component transcriptional regulator, DosR
	Mb3156c	dosS	two-component sensor histidine kinase, DosS
Position: -133 Score: 4.6 Sequence: TAGGGACAGAAGTCCCCG Position: -76 Score: 4.6 Sequence: TGGGGACCATTGACCCTG Locus tag: Mb2058 Name: acg Funciton: nitroreductase
	Mb2058	acg	nitroreductase
Position: -145 Score: 4.2 Sequence: AAGGGGCGAAAGTCCCTT Position: -63 Score: 4.1 Sequence: TCGTGACCGACGTCCCCA Position: -41 Score: 4.6 Sequence: CAAGGCCGAACGACCCTA Locus tag: Mb1762c Name: Rv1733c Funciton: probable conserved transmembrane protein Locus tag: Mb1761c Name: Rv1732c Funciton: hypothetical protein
	Mb1762c	Rv1733c	probable conserved transmembrane protein
	Mb1761c	Rv1732c	hypothetical protein
Position: -48 Score: 4.6 Sequence: TGGGGACCGAAGTCCCCG Locus tag: Mb1763c Name: Rv1734c Funciton: pyruvate dehydrogenase (E2 component)
	Mb1763c	Rv1734c	pyruvate dehydrogenase (E2 component)
Position: -138 Score: 4.6 Sequence: CAGGGTCAATGGTCCCCA Position: -81 Score: 4.6 Sequence: CGGGGACTTCTGTCCCTA Locus tag: Mb2057c Name: hspX Funciton: heat shock protein HspX_1 Locus tag: Mb2056c Name: Mb2055c Funciton: Erythromycin esterase Locus tag: Mb2055c Name: Mb2055c Funciton: Erythromycin esterase Locus tag: Mb2054c Name: pfkB Funciton: probable phosphofructokinase Locus tag: Mb2053c Name: usp Funciton: universal stress protein Locus tag: Mb2052c Name: dosT Funciton: two-component system sensor kinase, DosT Locus tag: Mb2051c Name: usp Funciton: universal stress protein Locus tag: Mb2050c Name: Rv2025c Funciton: hypotetical protein
	Mb2057c	hspX	heat shock protein HspX_1
	Mb2056c	Mb2055c	Erythromycin esterase
	Mb2055c	Mb2055c	Erythromycin esterase
	Mb2054c	pfkB	probable phosphofructokinase
	Mb2053c	usp	universal stress protein
	Mb2052c	dosT	two-component system sensor kinase, DosT
	Mb2051c	usp	universal stress protein
	Mb2050c	Rv2025c	hypotetical protein
Position: -255 Score: 3.8 Sequence: CGGGGCCGATCGGCATCA Position: -112 Score: 3.8 Sequence: ACGGGTCCATCGACCCGC Position: -89 Score: 4.2 Sequence: ACGGGTCAAACGACCCTA Locus tag: Mb2659c Name: Rv2626c Funciton: putative signal-transduction protein with CBS domains Locus tag: Mb2658c Name: Rv2625c Funciton: conserved transmembrane alanine and leucine rich protein Locus tag: Mb2657c Name: usp Funciton: universal stress protein
	Mb2659c	Rv2626c	putative signal-transduction protein with CBS domains
	Mb2658c	Rv2625c	conserved transmembrane alanine and leucine rich protein
	Mb2657c	usp	universal stress protein
Position: -93 Score: 4.3 Sequence: GGAGGACCTTTGGCCCTG Locus tag: Mb3154c Name: DGAT Funciton: wax-dgat acyltransferase
	Mb3154c	DGAT	wax-dgat acyltransferase
Position: -76 Score: 4.6 Sequence: TAAGGCCTTTGGTCCTTT Locus tag: Mb2030c Name: fdxA Funciton: 4Fe-4S ferredoxin, iron-sulfur binding protein
	Mb2030c	fdxA	4Fe-4S ferredoxin, iron-sulfur binding protein
Position: -109 Score: 4.3 Sequence: CAGGGCCAAAGGTCCTCC Locus tag: Mb3155 Name: Rv3131 Funciton: nitroreductase
	Mb3155	Rv3131	nitroreductase
Position: -291 Score: 4.2 Sequence: TGGGGTCTTTCGTCACTT Position: -121 Score: 3.7 Sequence: TAGGGCACTTGGGCCACC Position: -52 Score: 4.7 Sequence: GCGGGACGTAAGTCCCTA Locus tag: Mb2660c Name: null Funciton: hypothetical protein
	Mb2660c		hypothetical protein

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of DosR in Mycobacterium bovis AF2122/97

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --