Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of TrpR in Klebsiella pneumoniae subsp. pneumoniae MGH 78578

Properties
Regulator type: Transcription factor
TF locus tag: KPN_04848
Regulator family: TrpR
Regulation mode: repressor
Biological process: Tryptophan biosynthesis
Effector: Tryptophan
Regulog: TrpR - Enterobacteriales
Statistics of regulated genes:
- Genes 8
- Operons 4
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 44 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -198
Score: 6.3
Sequence: CGAACTAGTTAACTAGTACG
Locus tag: KPN_01257
Name: trpE
Funciton: Anthranilate synthase, aminase component (EC 4.1.3.27)
Locus tag: KPN_01256
Name: trpD
Funciton: Anthranilate synthase, amidotransferase component (EC 4.1.3.27) / Anthranilate phosphoribosyltransferase (EC 2.4.2.18)
Locus tag: KPN_01255
Name: trpC
Funciton: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)
Locus tag: KPN_01254
Name: trpB
Funciton: Tryptophan synthase beta chain (EC 4.2.1.20)
Locus tag: KPN_01253
Name: trpA
Funciton: Tryptophan synthase alpha chain (EC 4.2.1.20)
trpE
Anthranilate synthase, aminase component (EC 4.1.3.27)
trpD
Anthranilate synthase, amidotransferase component (EC 4.1.3.27) / Anthranilate phosphoribosyltransferase (EC 2.4.2.18)
trpC
Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)
trpB
Tryptophan synthase beta chain (EC 4.2.1.20)
trpA
Tryptophan synthase alpha chain (EC 4.2.1.20)

Position: -65
Score: 5.7
Sequence: TGTACTCGTTGAAGAGTACA
Locus tag: KPN_04848
Name: trpR
Funciton: Trp operon repressor
trpR
Trp operon repressor

Position: -71
Score: 5.9
Sequence: TGTACTCGTGTACTGGTACA
Locus tag: KPN_03569
Name: mtr
Funciton: Tryptophan-specific transport protein
mtr
Tryptophan-specific transport protein

Position: -162
Score: 4.9
Sequence: TGTACTAATACACTAGTACA
Locus tag: KPN_02162
Name: aroH
Funciton: 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (EC 2.5.1.54)
aroH
2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (EC 2.5.1.54)
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