Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of TrpR in Escherichia coli str. K-12 substr. MG1655

Properties
Regulator type: Transcription factor
TF locus tag: b4393
Regulator family: TrpR
Regulation mode: repressor
Biological process: Tryptophan biosynthesis
Effector: Tryptophan
Regulog: TrpR - Enterobacteriales
Statistics of regulated genes:
- Genes 11
- Operons 5
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 44 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -183
Score: 6.3
Sequence: CGAACTAGTTAACTAGTACG
Locus tag: b1264
Name: trpE
Funciton: Anthranilate synthase, aminase component (EC 4.1.3.27)
Locus tag: b1263
Name: trpD
Funciton: Anthranilate synthase, amidotransferase component (EC 4.1.3.27) / Anthranilate phosphoribosyltransferase (EC 2.4.2.18)
Locus tag: b1262
Name: trpC
Funciton: Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)
Locus tag: b1261
Name: trpB
Funciton: Tryptophan synthase beta chain (EC 4.2.1.20)
Locus tag: b1260
Name: trpA
Funciton: Tryptophan synthase alpha chain (EC 4.2.1.20)
trpE
Anthranilate synthase, aminase component (EC 4.1.3.27)
trpD
Anthranilate synthase, amidotransferase component (EC 4.1.3.27) / Anthranilate phosphoribosyltransferase (EC 2.4.2.18)
trpC
Indole-3-glycerol phosphate synthase (EC 4.1.1.48) / Phosphoribosylanthranilate isomerase (EC 5.3.1.24)
trpB
Tryptophan synthase beta chain (EC 4.2.1.20)
trpA
Tryptophan synthase alpha chain (EC 4.2.1.20)

Position: -66
Score: 5.3
Sequence: CGTACTCTTTAGCGAGTACA
Locus tag: b4393
Name: trpR
Funciton: Trp operon repressor
trpR
Trp operon repressor

Position: -72
Score: 5.9
Sequence: TGTACTCGTGTACTGGTACA
Locus tag: b3161
Name: mtr
Funciton: Tryptophan-specific transport protein
mtr
Tryptophan-specific transport protein

Position: -79
Score: 5.6
Sequence: TGTACTAGTTTGATGGTATG
Locus tag: b0388
Name: aroL
Funciton: Shikimate kinase III (EC 2.7.1.71)
Locus tag: b0389
Name: yaiA
Funciton: putative cytoplasmic protein
Locus tag: b0390
Name: aroM
Funciton: AroM family protein
aroL
Shikimate kinase III (EC 2.7.1.71)
yaiA
putative cytoplasmic protein
aroM
AroM family protein

Position: -164
Score: 5.3
Sequence: TGTACTAGAGAACTAGTGCA
Locus tag: b1704
Name: aroH
Funciton: 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (EC 2.5.1.54)
aroH
2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (EC 2.5.1.54)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD