Regulon of Fur in Serratia proteamaculans 568

Properties
Regulator type:	Transcription factor
TF locus tag:	Spro_1236
Regulator family:	FUR
Regulation mode:	repressor (activator)
Biological process:	Iron homeostasis
Effector:	Iron ion, (Fe2+)
Regulog:	Fur - Enterobacteriales
Statistics of regulated genes:
- Genes	70
- Operons	36
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 656 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - FUR
By TF family - FUR
By effector - Iron ion, (Fe2+)
By pathway - Iron homeostasis

Regulated operons
	Locus Tag	Name	Function
Position: -330 Score: 3.9 Sequence: GTTATCAAGAATGATTCTC Position: -324 Score: 4.2 Sequence: AAGAATGATTCTCAAAAAC Locus tag: Spro_2704 Name: adhE Funciton: iron-containing aldehyde-alcohol dehydrogenase
	Spro_2704	adhE	iron-containing aldehyde-alcohol dehydrogenase
Position: -64 Score: 4.9 Sequence: ACAAATGATTATCATTAGC Locus tag: Spro_3468 Name: cjrB Funciton: TonB family protein
	Spro_3468	cjrB	TonB family protein
Position: -51 Score: 5.1 Sequence: GCAAATGATAATTATTATC Position: -45 Score: 4.2 Sequence: GATAATTATTATCTATAAT Locus tag: Spro_3469 Name: cjrA Funciton: putative lipoprotein of unknown function DUF399
	Spro_3469	cjrA	putative lipoprotein of unknown function DUF399
Position: -114 Score: 4.1 Sequence: CTAAACAATAACCATTATC Position: -108 Score: 4.6 Sequence: AATAACCATTATCATTTCC Locus tag: Spro_1844 Name: null Funciton: lipoprotein
	Spro_1844		lipoprotein
Position: -93 Score: 4.3 Sequence: AATAATATTTATTGTTATC Locus tag: Spro_0923 Name: null Funciton: major facilitator superfamily MFS_1 Locus tag: Spro_0924 Name: null Funciton: FAD-binding 9 siderophore-interacting domain protein
	Spro_0923		major facilitator superfamily MFS_1
	Spro_0924		FAD-binding 9 siderophore-interacting domain protein
Position: -66 Score: 4.9 Sequence: GATATTGATATTAATTATC Position: -60 Score: 5.1 Sequence: GATATTAATTATCAATATC Position: -54 Score: 4.5 Sequence: AATTATCAATATCATTAGC Locus tag: Spro_3495 Name: null Funciton: putative receptor Locus tag: Spro_3496 Name: fhuE Funciton: TonB-dependent siderophore receptor
	Spro_3495		putative receptor
	Spro_3496	fhuE	TonB-dependent siderophore receptor
Position: -245 Score: 5 Sequence: GATATTGATAATTAATATC Position: -239 Score: 4.9 Sequence: GATAATTAATATCAATATC Position: -105 Score: 4 Sequence: TGTAATGATTTTCATTTCG Locus tag: Spro_3494 Name: null Funciton: TonB-dependent siderophore/colicin receptor
	Spro_3494		TonB-dependent siderophore/colicin receptor
Position: 24 Score: 4.8 Sequence: AAATATGATAATGATTATC Position: 30 Score: 5 Sequence: GATAATGATTATCATTCAA Locus tag: Spro_2178 Name: null Funciton: hypothetical protein
	Spro_2178		hypothetical protein
Position: -174 Score: 4.5 Sequence: GAAAATAGTTATCATAATT Position: -168 Score: 4 Sequence: AGTTATCATAATTATTTAA Locus tag: Spro_1942 Name: ftnA Funciton: ferritin
	Spro_1942	ftnA	ferritin
Position: -108 Score: 4.2 Sequence: ATGATTGATAAGTATTATC Position: -102 Score: 4.2 Sequence: GATAAGTATTATCGTTTGC Locus tag: Spro_3222 Name: yiuB Funciton: ferric-enterobactin ABC-transporter, permease component Locus tag: Spro_3221 Name: yiuC Funciton: ferric-enterobactin ABC transporter ATP-binding protein
	Spro_3222	yiuB	ferric-enterobactin ABC-transporter, permease component
	Spro_3221	yiuC	ferric-enterobactin ABC transporter ATP-binding protein
Position: -60 Score: 4.7 Sequence: GCTTATAATAATTATTATC Position: -54 Score: 4.7 Sequence: AATAATTATTATCGTTTAC Locus tag: Spro_3979 Name: null Funciton: TonB-dependent siderophore receptor Locus tag: Spro_3978 Name: null Funciton: iron-hydroxamate transporter ATP-binding subunit Locus tag: Spro_3977 Name: null Funciton: iron-hydroxamate transporter substrate-binding subunit Locus tag: Spro_3976 Name: null Funciton: iron-hydroxamate transporter permease subunit
	Spro_3979		TonB-dependent siderophore receptor
	Spro_3978		iron-hydroxamate transporter ATP-binding subunit
	Spro_3977		iron-hydroxamate transporter substrate-binding subunit
	Spro_3976		iron-hydroxamate transporter permease subunit
Position: -167 Score: 4.1 Sequence: CTGTATAATAATGATTATC Position: -161 Score: 5 Sequence: AATAATGATTATCATTTGT Locus tag: Spro_3422 Name: fepB Funciton: ferric enterobactin (enterochelin) binding protein; periplasmic component
	Spro_3422	fepB	ferric enterobactin (enterochelin) binding protein; periplasmic component
Position: -155 Score: 4.3 Sequence: GAATACGATAATGATTCTC Position: -149 Score: 4.9 Sequence: GATAATGATTCTCACTATT Locus tag: Spro_4628 Name: null Funciton: ferrous iron transport protein A Locus tag: Spro_4629 Name: null Funciton: ferrous iron transport protein B Locus tag: Spro_4630 Name: null Funciton: ferrous iron transport protein C
	Spro_4628		ferrous iron transport protein A
	Spro_4629		ferrous iron transport protein B
	Spro_4630		ferrous iron transport protein C
Position: -48 Score: 4.4 Sequence: AATAATGATAATAAAACTC Position: -42 Score: 4.4 Sequence: GATAATAAAACTCATTTAT Locus tag: Spro_3424 Name: fepD Funciton: iron-enterobactin (enterochelin) ABC transporter membrane protein Locus tag: Spro_3425 Name: fepG Funciton: iron-enterobactin (enterochelin) ABC transporter membrane protein Locus tag: Spro_3426 Name: fepC Funciton: iron-enterobactin (enterochelin) ABC transport ATPase
	Spro_3424	fepD	iron-enterobactin (enterochelin) ABC transporter membrane protein
	Spro_3425	fepG	iron-enterobactin (enterochelin) ABC transporter membrane protein
	Spro_3426	fepC	iron-enterobactin (enterochelin) ABC transport ATPase
Position: -143 Score: 4.8 Sequence: AATAATGATTACTATTCTC Locus tag: Spro_0586 Name: yncE Funciton: putative receptor, ATP binding
	Spro_0586	yncE	putative receptor, ATP binding
Position: -112 Score: 4.4 Sequence: ATAAATGAGTTTTATTATC Position: -106 Score: 4.4 Sequence: GAGTTTTATTATCATTATT Locus tag: Spro_3423 Name: ybdA Funciton: enterobactin exporter EntS, MFS family
	Spro_3423	ybdA	enterobactin exporter EntS, MFS family
Position: -243 Score: 4.6 Sequence: GATAATGAGAACTAATATC Locus tag: Spro_0645 Name: hmsT Funciton: diguanylate cyclase, involved in hemin storage
	Spro_0645	hmsT	diguanylate cyclase, involved in hemin storage
Position: -41 Score: 5.4 Sequence: GATATTGATAATCATTTTC Position: -35 Score: 4.6 Sequence: GATAATCATTTTCATTTGA Locus tag: Spro_2133 Name: sitA Funciton: iron ABC transporter, periplasmic substrate-binding protein Locus tag: Spro_2132 Name: sitB Funciton: ATP-binding protein for iron and manganese ABC transporter Locus tag: Spro_2131 Name: sitC Funciton: iron ABC transporter, membrane protein Locus tag: Spro_2130 Name: sitD Funciton: iron ABC transporter, membrane protein
	Spro_2133	sitA	iron ABC transporter, periplasmic substrate-binding protein
	Spro_2132	sitB	ATP-binding protein for iron and manganese ABC transporter
	Spro_2131	sitC	iron ABC transporter, membrane protein
	Spro_2130	sitD	iron ABC transporter, membrane protein
Position: -51 Score: 4.9 Sequence: TATAATGATTTTCGTTATC Locus tag: Spro_1288 Name: gpmA Funciton: phosphoglyceromutase 1
	Spro_1288	gpmA	phosphoglyceromutase 1
Position: -68 Score: 4 Sequence: TCACATGATAATGATTCTC Position: -62 Score: 4.6 Sequence: GATAATGATTCTCACTTTG Locus tag: Spro_2170 Name: hemP Funciton: hemin uptake protein Locus tag: Spro_2169 Name: hemR Funciton: TonB-dependent outer membrane hemin receptor Locus tag: Spro_2168 Name: hemS Funciton: hemin transport protein Locus tag: Spro_2167 Name: hemT Funciton: hemin ABC transporter, substrate-binding protein Locus tag: Spro_2166 Name: hemU Funciton: hemin transport ABC permease protein Locus tag: Spro_2165 Name: hemV Funciton: hemin transport system ATP-binding protein
	Spro_2170	hemP	hemin uptake protein
	Spro_2169	hemR	TonB-dependent outer membrane hemin receptor
	Spro_2168	hemS	hemin transport protein
	Spro_2167	hemT	hemin ABC transporter, substrate-binding protein
	Spro_2166	hemU	hemin transport ABC permease protein
	Spro_2165	hemV	hemin transport system ATP-binding protein
Position: -77 Score: 4.4 Sequence: TGAAGTGATAATCGTTATC Position: -71 Score: 4.7 Sequence: GATAATCGTTATCACTAAC Locus tag: Spro_2179 Name: sufA Funciton: scaffold protein for iron-sulfur cluster assembly Locus tag: Spro_2180 Name: sufB Funciton: FeS assembly protein Locus tag: Spro_2181 Name: sufC Funciton: FeS assembly ATPase Locus tag: Spro_2182 Name: sufD Funciton: FeS assembly protein Locus tag: Spro_2183 Name: sufS Funciton: Selenocysteine lyase Locus tag: Spro_2184 Name: sufE Funciton: cysteine desulfuration protein
	Spro_2179	sufA	scaffold protein for iron-sulfur cluster assembly
	Spro_2180	sufB	FeS assembly protein
	Spro_2181	sufC	FeS assembly ATPase
	Spro_2182	sufD	FeS assembly protein
	Spro_2183	sufS	Selenocysteine lyase
	Spro_2184	sufE	cysteine desulfuration protein
Position: -39 Score: 4.7 Sequence: GATATTAGTTCTCATTATC Locus tag: Spro_0646 Name: yjjZ Funciton: putative membrane protein
	Spro_0646	yjjZ	putative membrane protein
Position: -150 Score: 4.1 Sequence: GTTAATTAAAATCAATAGT Position: -96 Score: 4.2 Sequence: GCTAACTATTTTCATTTTT Locus tag: Spro_2926 Name: yncD Funciton: TonB-dependent siderophore outer membrane receptor
	Spro_2926	yncD	TonB-dependent siderophore outer membrane receptor
Position: -128 Score: 4.6 Sequence: CGCAATAATAATCATTATC Position: -122 Score: 4.7 Sequence: AATAATCATTATCATTCGT Locus tag: Spro_4654 Name: yhhY Funciton: GCN5-related N-acetyltransferase
	Spro_4654	yhhY	GCN5-related N-acetyltransferase
Position: -65 Score: 4.5 Sequence: GCAAACAATTCTCATTATC Locus tag: Spro_2919 Name: viuB Funciton: FAD-binding 9 siderophore-interacting domain protein
	Spro_2919	viuB	FAD-binding 9 siderophore-interacting domain protein
Position: -140 Score: 4.9 Sequence: GATAAAGATAATAATTATC Position: -134 Score: 5.2 Sequence: GATAATAATTATCATTAAT Locus tag: Spro_2736 Name: foxR Funciton: TonB-dependent siderophore receptor
	Spro_2736	foxR	TonB-dependent siderophore receptor
Position: -109 Score: 4.8 Sequence: CAGAATGATAATCACTATC Locus tag: Spro_2929 Name: yijD Funciton: iron permease FTR1 Locus tag: Spro_2928 Name: ycdO Funciton: Ferrous ion transport periplasmic protein Locus tag: Spro_2927 Name: ycdB Funciton: Dyp-type peroxidase
	Spro_2929	yijD	iron permease FTR1
	Spro_2928	ycdO	Ferrous ion transport periplasmic protein
	Spro_2927	ycdB	Dyp-type peroxidase
Position: -56 Score: 5 Sequence: ACAAATGATAATCATTATT Position: -50 Score: 4.1 Sequence: GATAATCATTATTATACAG Locus tag: Spro_3421 Name: null Funciton: isochorismate synthetase, siderophore biosynthesis Locus tag: Spro_3420 Name: null Funciton: 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase complex Locus tag: Spro_3419 Name: null Funciton: enterobactin synthetase component B (isochorismatase) Locus tag: Spro_3418 Name: null Funciton: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, enterochelin biosynthesis
	Spro_3421		isochorismate synthetase, siderophore biosynthesis
	Spro_3420		2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase complex
	Spro_3419		enterobactin synthetase component B (isochorismatase)
	Spro_3418		2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, enterochelin biosynthesis
Position: -66 Score: 4.3 Sequence: GCACTTGATAATTATTATC Position: -60 Score: 5.2 Sequence: GATAATTATTATCATTTAC Locus tag: Spro_3415 Name: mntH Funciton: Mn2+/Fe2+ transporter, NRAMP family
	Spro_3415	mntH	Mn2+/Fe2+ transporter, NRAMP family
Position: -105 Score: 4.7 Sequence: GGCATTGATAATCATTTTC Position: -99 Score: 5 Sequence: GATAATCATTTTCAATATC Locus tag: Spro_0081 Name: sodA Funciton: manganese/iron superoxide dismutase
	Spro_0081	sodA	manganese/iron superoxide dismutase
Position: -94 Score: 4.4 Sequence: AATAATGAGAACTACTATC Locus tag: Spro_4211 Name: exbB Funciton: TonB-dependent siderophore transporter component ExbB Locus tag: Spro_4210 Name: exbD Funciton: TonB-dependent siderophore transporter component ExbD
	Spro_4211	exbB	TonB-dependent siderophore transporter component ExbB
	Spro_4210	exbD	TonB-dependent siderophore transporter component ExbD
Position: -74 Score: 5.5 Sequence: GATATTGATAATCATTATC Position: -68 Score: 5.1 Sequence: GATAATCATTATCAATATT Locus tag: Spro_1429 Name: ubiF Funciton: flavoprotein monooxygenase
	Spro_1429	ubiF	flavoprotein monooxygenase
Position: -260 Score: 4.4 Sequence: ACTATTGATAATTATTTGC Position: -254 Score: 4.1 Sequence: GATAATTATTTGCGTTTGC Locus tag: Spro_3430 Name: iroN Funciton: TonB-dependent siderophore receptor
	Spro_3430	iroN	TonB-dependent siderophore receptor
Position: -52 Score: 4.3 Sequence: GCTAATGAGAGTGATTATC Locus tag: Spro_1015 Name: null Funciton: iron(III) ABC transporter, periplasmic protein Locus tag: Spro_1016 Name: null Funciton: TonB-dependent siderophore receptor
	Spro_1015		iron(III) ABC transporter, periplasmic protein
	Spro_1016		TonB-dependent siderophore receptor
Position: -63 Score: 4.2 Sequence: GATAACAATAAATATTATT Position: -45 Score: 4.1 Sequence: TGATATAAGAATCATTCTC Locus tag: Spro_0922 Name: iucA Funciton: aerobactin synthetase (subunit alpha) Locus tag: Spro_0921 Name: iucB Funciton: acetyl CoA:N6-hydroxylsyine acetyl transferase, siderophore biosynthesis Locus tag: Spro_0920 Name: iucC Funciton: aerobactin synthetase (subunit beta) Locus tag: Spro_0919 Name: iucD Funciton: L-lysine 6-monooxygenase (NADPH), siderophore biosynthesis Locus tag: Spro_0918 Name: iutA Funciton: TonB-dependent siderophore receptor
	Spro_0922	iucA	aerobactin synthetase (subunit alpha)
	Spro_0921	iucB	acetyl CoA:N6-hydroxylsyine acetyl transferase, siderophore biosynthesis
	Spro_0920	iucC	aerobactin synthetase (subunit beta)
	Spro_0919	iucD	L-lysine 6-monooxygenase (NADPH), siderophore biosynthesis
	Spro_0918	iutA	TonB-dependent siderophore receptor
Position: -91 Score: 4.7 Sequence: ATTAATAAAAATTATTATC Position: -85 Score: 4.8 Sequence: AAAAATTATTATCATTTGC Locus tag: Spro_2539 Name: Spro_2539 Funciton: iron(III) ABC transporter, binding protein
	Spro_2539	Spro_2539	iron(III) ABC transporter, binding protein

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of Fur in Serratia proteamaculans 568

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --