Regulon of Fur in Salmonella typhimurium LT2

Properties
Regulator type:	Transcription factor
TF locus tag:	STM0693
Regulator family:	FUR
Regulation mode:	repressor (activator)
Biological process:	Iron homeostasis
Effector:	Iron ion, (Fe2+)
Regulog:	Fur - Enterobacteriales
Statistics of regulated genes:
- Genes	55
- Operons	29
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 656 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - FUR
By TF family - FUR
By effector - Iron ion, (Fe2+)
By pathway - Iron homeostasis

Regulated operons
	Locus Tag	Name	Function
Position: -100 Score: 4 Sequence: AATAATTAAATTTAATATT Locus tag: STM1935 Name: ftnA Funciton: ferritin
	STM1935	ftnA	ferritin
Position: -26 Score: 4.5 Sequence: GGTAATAATTCTTATTTAC Locus tag: STM0364 Name: foxA Funciton: TonB-dependent siderophore receptor
	STM0364	foxA	TonB-dependent siderophore receptor
Position: -116 Score: 4.8 Sequence: TTGAATGATAATTATTATC Position: -110 Score: 5.2 Sequence: GATAATTATTATCATTAGC Locus tag: STM2777 Name: iroN Funciton: TonB-dependent siderophore receptor
	STM2777	iroN	TonB-dependent siderophore receptor
Position: -44 Score: 4.4 Sequence: ATTCATAATAATGATTATC Position: -38 Score: 5.3 Sequence: AATAATGATTATCAATATC Locus tag: STM1950 Name: sdiA Funciton: transcriptional regulator of ftsQAZ gene cluster (LuxR/UhpA family)
	STM1950	sdiA	transcriptional regulator of ftsQAZ gene cluster (LuxR/UhpA family)
Position: -179 Score: 5.1 Sequence: GAGAATAATAATCATTATT Locus tag: STM1587 Name: yncD Funciton: TonB-dependent siderophore outer membrane receptor
	STM1587	yncD	TonB-dependent siderophore outer membrane receptor
Position: -82 Score: 4.9 Sequence: TATAATGATACGCATTATC Locus tag: STM0693 Name: fur Funciton: ferric uptake transcription regulator
	STM0693	fur	ferric uptake transcription regulator
Position: -140 Score: 3.5 Sequence: GAagATagaAAcCATTcTC Position: -133 Score: 4.5 Sequence: AGAAACCATTCTCATTATC Locus tag: STM3505 Name: feoA Funciton: ferrous iron transport protein A Locus tag: STM3506 Name: feoB Funciton: ferrous iron transport protein B Locus tag: STM3507 Name: yhgG Funciton: ferrous iron transport protein C
	STM3505	feoA	ferrous iron transport protein A
	STM3506	feoB	ferrous iron transport protein B
	STM3507	yhgG	ferrous iron transport protein C
Position: -37 Score: 4.8 Sequence: GATAACGATAATTACTATC Position: -31 Score: 5 Sequence: GATAATTACTATCATTATC Locus tag: STM0592 Name: fepD Funciton: iron-enterobactin (enterochelin) ABC transporter membrane protein Locus tag: STM0591 Name: fepG Funciton: iron-enterobactin (enterochelin) ABC transporter membrane protein Locus tag: STM0590 Name: fepC Funciton: iron-enterobactin (enterochelin) ABC transport ATPase
	STM0592	fepD	iron-enterobactin (enterochelin) ABC transporter membrane protein
	STM0591	fepG	iron-enterobactin (enterochelin) ABC transporter membrane protein
	STM0590	fepC	iron-enterobactin (enterochelin) ABC transport ATPase
Position: -98 Score: 4.9 Sequence: GATAATGATAGTAATTATC Position: -92 Score: 4.8 Sequence: GATAGTAATTATCGTTATC Locus tag: STM0593 Name: ybdA Funciton: enterobactin exporter EntS, MFS family
	STM0593	ybdA	enterobactin exporter EntS, MFS family
Position: -160 Score: 4.2 Sequence: TATAATAATGATTATTATT Position: -157 Score: 4.6 Sequence: AATAATGATTATTATTTCT Locus tag: STM0594 Name: fepB Funciton: ferric enterobactin (enterochelin) binding protein; periplasmic component
	STM0594	fepB	ferric enterobactin (enterochelin) binding protein; periplasmic component
Position: -56 Score: 4.8 Sequence: GGTTATAATAATAATTATC Position: -50 Score: 4.8 Sequence: AATAATAATTATCGTTTAC Locus tag: STM0191 Name: fhuA Funciton: TonB-dependent siderophore receptor Locus tag: STM0192 Name: fhuC Funciton: iron-hydroxamate transporter ATP-binding subunit Locus tag: STM0193 Name: fhuD Funciton: iron-hydroxamate transporter substrate-binding subunit Locus tag: STM0194 Name: fhuB Funciton: iron-hydroxamate transporter permease subunit
	STM0191	fhuA	TonB-dependent siderophore receptor
	STM0192	fhuC	iron-hydroxamate transporter ATP-binding subunit
	STM0193	fhuD	iron-hydroxamate transporter substrate-binding subunit
	STM0194	fhuB	iron-hydroxamate transporter permease subunit
Position: -132 Score: 4.1 Sequence: ATTATTGATAACTATTTGC Position: -126 Score: 4 Sequence: GATAACTATTTGCATTTGC Locus tag: STM0585 Name: fepA Funciton: TonB-dependent siderophore receptor FepA Locus tag: STM0584 Name: entD Funciton: enterochelin synthetase, component D (phoshpantetheinyltransferase)
	STM0585	fepA	TonB-dependent siderophore receptor FepA
	STM0584	entD	enterochelin synthetase, component D (phoshpantetheinyltransferase)
Position: -37 Score: 5.2 Sequence: GATATTGGTTATCATTATC Position: -31 Score: 4.2 Sequence: GGTTATCATTATCAATTCC Locus tag: STM4552 Name: yjjZ Funciton: putative membrane protein
	STM4552	yjjZ	putative membrane protein
Position: -66 Score: 4.7 Sequence: TGAAGTGATAATCATTATC Position: -60 Score: 5.1 Sequence: GATAATCATTATCACTAAC Locus tag: STM1369 Name: sufA Funciton: scaffold protein for iron-sulfur cluster assembly Locus tag: STM1370 Name: sufB Funciton: FeS assembly protein Locus tag: STM1371 Name: sufC Funciton: FeS assembly ATPase Locus tag: STM1372 Name: sufD Funciton: FeS assembly protein Locus tag: STM1373 Name: sufS Funciton: Selenocysteine lyase Locus tag: STM1374 Name: sufE Funciton: cysteine desulfuration protein
	STM1369	sufA	scaffold protein for iron-sulfur cluster assembly
	STM1370	sufB	FeS assembly protein
	STM1371	sufC	FeS assembly ATPase
	STM1372	sufD	FeS assembly protein
	STM1373	sufS	Selenocysteine lyase
	STM1374	sufE	cysteine desulfuration protein
Position: -238 Score: 4 Sequence: GGAATTGATAATGATAACC Position: -232 Score: 5.1 Sequence: GATAATGATAACCAATATC Locus tag: STM4551 Name: hmsT Funciton: diguanylate cyclase, involved in hemin storage Locus tag: STM4550 Name: fhuF Funciton: ferric iron reductase involved in ferric hydroximate transport
	STM4551	hmsT	diguanylate cyclase, involved in hemin storage
	STM4550	fhuF	ferric iron reductase involved in ferric hydroximate transport
Position: -99 Score: 4.5 Sequence: GCAAATAAGAATTATTTTC Position: -93 Score: 4.2 Sequence: AAGAATTATTTTCATTTAT Locus tag: STM2861 Name: sitA Funciton: iron ABC transporter, periplasmic substrate-binding protein Locus tag: STM2862 Name: sitB Funciton: ATP-binding protein for iron and manganese ABC transporter Locus tag: STM2863 Name: sitC Funciton: iron ABC transporter, membrane protein Locus tag: STM2864 Name: sitD Funciton: iron ABC transporter, membrane protein
	STM2861	sitA	iron ABC transporter, periplasmic substrate-binding protein
	STM2862	sitB	ATP-binding protein for iron and manganese ABC transporter
	STM2863	sitC	iron ABC transporter, membrane protein
	STM2864	sitD	iron ABC transporter, membrane protein
Position: -47 Score: 5 Sequence: TATAATGAGAATTATTATC Position: -41 Score: 4.5 Sequence: GAGAATTATTATCATTACA Locus tag: STM0772 Name: gpmA Funciton: phosphoglyceromutase 1
	STM0772	gpmA	phosphoglyceromutase 1
Position: -47 Score: 4.5 Sequence: ATTATTGATAATAATAATC Position: -41 Score: 4.7 Sequence: GATAATAATAATCATTGTG Locus tag: STM1346 Name: hemP Funciton: hemin uptake protein
	STM1346	hemP	hemin uptake protein
Position: -55 Score: 4.6 Sequence: TGTAATCATAACCATTCTC Position: -49 Score: 4.3 Sequence: CATAACCATTCTCATTTAC Locus tag: STM3444 Name: bfd Funciton: bacterioferritin-associated ferredoxin Locus tag: STM3443 Name: bfr Funciton: bacterioferrin
	STM3444	bfd	bacterioferritin-associated ferredoxin
	STM3443	bfr	bacterioferrin
Position: -119 Score: 4.7 Sequence: GGCAATAATAATCATTCTC Position: -113 Score: 4.7 Sequence: AATAATCATTCTCATTCGC Locus tag: STM3546 Name: yhhY Funciton: GCN5-related N-acetyltransferase
	STM3546	yhhY	GCN5-related N-acetyltransferase
Position: -103 Score: 5.2 Sequence: AATAATGATTATTATTCTC Locus tag: STM1586 Name: yncE Funciton: putative receptor, ATP binding
	STM1586	yncE	putative receptor, ATP binding
Position: -99 Score: 4.7 Sequence: GGCATTGATAATCATTTTC Position: -93 Score: 5 Sequence: GATAATCATTTTCAATATC Locus tag: STM4055 Name: sodA Funciton: manganese/iron superoxide dismutase
	STM4055	sodA	manganese/iron superoxide dismutase
Position: -170 Score: 4.9 Sequence: AGAAATAATAATCATTATT Position: -164 Score: 4.4 Sequence: AATAATCATTATTATACAC Locus tag: STM0595 Name: entC Funciton: isochorismate synthetase, siderophore biosynthesis Locus tag: STM0596 Name: entE Funciton: 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase complex Locus tag: STM0597 Name: entB Funciton: enterobactin synthetase component B (isochorismatase) Locus tag: STM0598 Name: entA Funciton: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, enterochelin biosynthesis Locus tag: STM0599 Name: ybdB Funciton: putative protein PaaI, possibly involved in aromatic compounds catabolism
	STM0595	entC	isochorismate synthetase, siderophore biosynthesis
	STM0596	entE	2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase complex
	STM0597	entB	enterobactin synthetase component B (isochorismatase)
	STM0598	entA	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, enterochelin biosynthesis
	STM0599	ybdB	putative protein PaaI, possibly involved in aromatic compounds catabolism
Position: -68 Score: 4.5 Sequence: GCACTTGATAATCATTATC Position: -62 Score: 4.8 Sequence: GATAATCATTATCAATAAA Locus tag: STM2408 Name: mntH Funciton: Mn2+/Fe2+ transporter, NRAMP family
	STM2408	mntH	Mn2+/Fe2+ transporter, NRAMP family
Position: -62 Score: 4.3 Sequence: AACAATCATTATCATTTAA Locus tag: STM3214 Name: yqjH Funciton: FAD-binding 9, siderophore-interacting domain protein
	STM3214	yqjH	FAD-binding 9, siderophore-interacting domain protein
Position: -188 Score: 4.4 Sequence: TAAAATGAGAATTATTACC Position: -136 Score: 4 Sequence: TTTAATCAAAATAAATATT Locus tag: STM0831 Name: dps Funciton: DNA protection ferritin-like protein
	STM0831	dps	DNA protection ferritin-like protein
Position: -201 Score: 4.9 Sequence: TAAATTGATAATTATTATC Position: -195 Score: 4.8 Sequence: GATAATTATTATCGTTTGC Locus tag: STM2199 Name: cirA Funciton: TonB-dependent ferric iron-catecholate receptor
	STM2199	cirA	TonB-dependent ferric iron-catecholate receptor
Position: -82 Score: 4.1 Sequence: AGTAATGAGAACGACTATC Locus tag: STM3159 Name: exbB Funciton: TonB-dependent siderophore transporter component ExbB Locus tag: STM3158 Name: exbD Funciton: TonB-dependent siderophore transporter component ExbD
	STM3159	exbB	TonB-dependent siderophore transporter component ExbB
	STM3158	exbD	TonB-dependent siderophore transporter component ExbD
Position: -70 Score: 4.9 Sequence: GATATTGGTAATTATTATC Position: -64 Score: 5.1 Sequence: GGTAATTATTATCATTCTC Position: -58 Score: 4.5 Sequence: TATTATCATTCTCATTAAC Locus tag: STM2773 Name: iroB Funciton: putative glycosyl transferase, related to UDP-glucuronosyltransferase Locus tag: STM2774 Name: iroC Funciton: putative ABC transporter, ATPase and permease components Locus tag: STM2775 Name: iroD Funciton: Similar to enterochelin esterase of E. coli (Fes) Locus tag: STM2776 Name: iroE Funciton: putative hydrolase of the alpha/beta superfamily
	STM2773	iroB	putative glycosyl transferase, related to UDP-glucuronosyltransferase
	STM2774	iroC	putative ABC transporter, ATPase and permease components
	STM2775	iroD	Similar to enterochelin esterase of E. coli (Fes)
	STM2776	iroE	putative hydrolase of the alpha/beta superfamily

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of Fur in Salmonella typhimurium LT2

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --