Regulon of Fur in Escherichia coli str. K-12 substr. MG1655

Properties
Regulator type:	Transcription factor
TF locus tag:	b0683
Regulator family:	FUR
Regulation mode:	repressor (activator)
Biological process:	Iron homeostasis
Effector:	Iron ion, (Fe2+)
Regulog:	Fur - Enterobacteriales
Statistics of regulated genes:
- Genes	66
- Operons	30
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 656 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - FUR
By TF family - FUR
By effector - Iron ion, (Fe2+)
By pathway - Iron homeostasis

Regulated operons
	Locus Tag	Name	Function
Position: -267 Score: 4.5 Sequence: TCAAATGATAATAAATATC Locus tag: b1674 Name: ydhY Funciton: oxidoreductase, Fe-S subunit Locus tag: b1673 Name: ydhV Funciton: aldehyde ferredoxin oxidoreductase Locus tag: b1672 Name: ydhW Funciton: subunit of oxidoreductase Locus tag: b1671 Name: ydhX Funciton: 4Fe-4S ferridoxin-type protein Locus tag: b1670 Name: ydhU Funciton: oxidoreductase, cytochrome b subunit Locus tag: b1669 Name: ydhT Funciton: subunit of oxidoreductase
	b1674	ydhY	oxidoreductase, Fe-S subunit
	b1673	ydhV	aldehyde ferredoxin oxidoreductase
	b1672	ydhW	subunit of oxidoreductase
	b1671	ydhX	4Fe-4S ferridoxin-type protein
	b1670	ydhU	oxidoreductase, cytochrome b subunit
	b1669	ydhT	subunit of oxidoreductase
Position: -127 Score: 3.4 Sequence: GgTAATGcgttTtATTccC Position: -121 Score: 3 Sequence: GcgttTtATtccCATTcgt Locus tag: b1905 Name: ftnA Funciton: ferritin
	b1905	ftnA	ferritin
Position: -4 Score: 4.4 Sequence: GCTAATGATAACCATTCCC Locus tag: b1496 Name: yddA Funciton: fused predicted multidrug transporter subunits of ABC superfamily: membrane component/ATP-binding component Locus tag: b1495 Name: yddB Funciton: TonB-dependent receptor
	b1496	yddA	fused predicted multidrug transporter subunits of ABC superfamily: membrane component/ATP-binding component
	b1495	yddB	TonB-dependent receptor
Position: -123 Score: 4.4 Sequence: GCTTATCAAAATTATTATC Position: -117 Score: 4.5 Sequence: CAAAATTATTATCACTTTC Locus tag: b0805 Name: fiu Funciton: iron outer membrane transporter Locus tag: b0804 Name: ybiX Funciton: 2OG-Fe(II) oxygenase
	b0805	fiu	iron outer membrane transporter
	b0804	ybiX	2OG-Fe(II) oxygenase
Position: -184 Score: 4.1 Sequence: ATTATTGATAACTATTTGC Position: -178 Score: 4 Sequence: GATAACTATTTGCATTTGC Locus tag: b0584 Name: fepA Funciton: TonB-dependent siderophore receptor FepA Locus tag: b0583 Name: entD Funciton: enterochelin synthetase, component D (phoshpantetheinyltransferase)
	b0584	fepA	TonB-dependent siderophore receptor FepA
	b0583	entD	enterochelin synthetase, component D (phoshpantetheinyltransferase)
Position: -38 Score: 4.4 Sequence: ATAAATGATACTCACTCTC Locus tag: b1916 Name: sdiA Funciton: transcriptional regulator of ftsQAZ gene cluster (LuxR/UhpA family)
	b1916	sdiA	transcriptional regulator of ftsQAZ gene cluster (LuxR/UhpA family)
Position: -63 Score: 4.7 Sequence: TGTAATGATAACCATTCTC Position: -57 Score: 4.1 Sequence: GATAACCATTCTCATATTA Locus tag: b4293 Name: fecI Funciton: ECF-family RNA polymerase sigma factor fecI Locus tag: b4292 Name: fecR Funciton: transmembrane signal transducer for ferric citrate transport Locus tag: b4291 Name: fecA Funciton: Iron(III) dicitrate outer membrane transporter precursor protein FecA Locus tag: b4290 Name: fecB Funciton: iron(III) dicitrate-binding periplasmic protein Locus tag: b4289 Name: fecC Funciton: Iron(III) dicitrate transport system permease protein FecC Locus tag: b4288 Name: fecD Funciton: Iron(III) dicitrate transport system permease protein FecD Locus tag: b4287 Name: fecE Funciton: Iron(III) dicitrate transport ATP-binding protein FecE
	b4293	fecI	ECF-family RNA polymerase sigma factor fecI
	b4292	fecR	transmembrane signal transducer for ferric citrate transport
	b4291	fecA	Iron(III) dicitrate outer membrane transporter precursor protein FecA
	b4290	fecB	iron(III) dicitrate-binding periplasmic protein
	b4289	fecC	Iron(III) dicitrate transport system permease protein FecC
	b4288	fecD	Iron(III) dicitrate transport system permease protein FecD
	b4287	fecE	Iron(III) dicitrate transport ATP-binding protein FecE
Position: -157 Score: 4.7 Sequence: GGGAATGGTAATCATTATT Locus tag: b1451 Name: yncD Funciton: TonB-dependent siderophore outer membrane receptor
	b1451	yncD	TonB-dependent siderophore outer membrane receptor
Position: -37 Score: 4.8 Sequence: GATAACGATAATTAATTTC Position: -31 Score: 4.9 Sequence: GATAATTAATTTCATTATC Locus tag: b0590 Name: fepD Funciton: iron-enterobactin (enterochelin) ABC transporter membrane protein Locus tag: b0589 Name: fepG Funciton: iron-enterobactin (enterochelin) ABC transporter membrane protein Locus tag: b0588 Name: fepC Funciton: iron-enterobactin (enterochelin) ABC transport ATPase
	b0590	fepD	iron-enterobactin (enterochelin) ABC transporter membrane protein
	b0589	fepG	iron-enterobactin (enterochelin) ABC transporter membrane protein
	b0588	fepC	iron-enterobactin (enterochelin) ABC transport ATPase
Position: -138 Score: 3.4 Sequence: GcTgATagaAAcCATTcTC Position: -132 Score: 4.5 Sequence: AGAAACCATTCTCATTATC Locus tag: b3408 Name: feoA Funciton: ferrous iron transport protein A Locus tag: b3409 Name: feoB Funciton: ferrous iron transport protein B Locus tag: b3410 Name: yhgG Funciton: ferrous iron transport protein C
	b3408	feoA	ferrous iron transport protein A
	b3409	feoB	ferrous iron transport protein B
	b3410	yhgG	ferrous iron transport protein C
Position: -98 Score: 4.8 Sequence: GATAATGAAATTAATTATC Position: -92 Score: 4.9 Sequence: GAAATTAATTATCGTTATC Locus tag: b0591 Name: ybdA Funciton: enterobactin exporter EntS, MFS family
	b0591	ybdA	enterobactin exporter EntS, MFS family
Position: -230 Score: 4.7 Sequence: GAAAATGAGAAGCATTATT Locus tag: b0592 Name: fepB Funciton: ferric enterobactin (enterochelin) binding protein; periplasmic component
	b0592	fepB	ferric enterobactin (enterochelin) binding protein; periplasmic component
Position: -57 Score: 4.4 Sequence: CTTTATAATAATCATTCTC Position: -51 Score: 4.5 Sequence: AATAATCATTCTCGTTTAC Locus tag: b0150 Name: fhuA Funciton: TonB-dependent siderophore receptor Locus tag: b0151 Name: fhuC Funciton: iron-hydroxamate transporter ATP-binding subunit Locus tag: b0152 Name: fhuD Funciton: iron-hydroxamate transporter substrate-binding subunit Locus tag: b0153 Name: fhuB Funciton: iron-hydroxamate transporter permease subunit
	b0150	fhuA	TonB-dependent siderophore receptor
	b0151	fhuC	iron-hydroxamate transporter ATP-binding subunit
	b0152	fhuD	iron-hydroxamate transporter substrate-binding subunit
	b0153	fhuB	iron-hydroxamate transporter permease subunit
Position: -60 Score: 4.4 Sequence: GCAAATGATAAAAATTATC Position: -37 Score: 5.2 Sequence: GATATTGGTTATCATTATC Locus tag: b4567 Name: yjjZ Funciton: putative membrane protein
	b4567	yjjZ	putative membrane protein
Position: -65 Score: 4.4 Sequence: TGAACTGATAATCATTATC Position: -59 Score: 5.1 Sequence: GATAATCATTATCACTAAC Locus tag: b1684 Name: sufA Funciton: scaffold protein for iron-sulfur cluster assembly Locus tag: b1683 Name: sufB Funciton: FeS assembly protein Locus tag: b1682 Name: sufC Funciton: FeS assembly ATPase Locus tag: b1681 Name: sufD Funciton: FeS assembly protein Locus tag: b1680 Name: sufS Funciton: Selenocysteine lyase Locus tag: b1679 Name: sufE Funciton: cysteine desulfuration protein
	b1684	sufA	scaffold protein for iron-sulfur cluster assembly
	b1683	sufB	FeS assembly protein
	b1682	sufC	FeS assembly ATPase
	b1681	sufD	FeS assembly protein
	b1680	sufS	Selenocysteine lyase
	b1679	sufE	cysteine desulfuration protein
Position: -122 Score: 5.1 Sequence: GATAATGATAACCAATATC Position: -99 Score: 4.5 Sequence: GATAATTTTTATCATTTGC Position: -34 Score: 4 Sequence: AGCAATCATTATCATTTAG Locus tag: b4367 Name: fhuF Funciton: ferric iron reductase involved in ferric hydroximate transport
	b4367	fhuF	ferric iron reductase involved in ferric hydroximate transport
Position: -47 Score: 5 Sequence: TATAATGAGAATTATTATC Position: -41 Score: 4.7 Sequence: GAGAATTATTATCATTAAA Locus tag: b0755 Name: gpmA Funciton: phosphoglyceromutase 1
	b0755	gpmA	phosphoglyceromutase 1
Position: -47 Score: 4.1 Sequence: AATATTGATAATAAGAATC Position: -41 Score: 4.6 Sequence: GATAATAAGAATCATTGTT Locus tag: b1705 Name: hemP Funciton: hemin uptake protein
	b1705	hemP	hemin uptake protein
Position: -119 Score: 4.9 Sequence: GACAATAATAATCATTCTC Position: -113 Score: 4.7 Sequence: AATAATCATTCTCATTCGC Locus tag: b3441 Name: yhhY Funciton: GCN5-related N-acetyltransferase
	b3441	yhhY	GCN5-related N-acetyltransferase
Position: -51 Score: 3.9 Sequence: tgaAATaAgAActATTtTC Position: -45 Score: 3.9 Sequence: aAgAActATttTCATTtat Locus tag: b3337 Name: bfd Funciton: bacterioferritin-associated ferredoxin Locus tag: b3336 Name: bfr Funciton: bacterioferrin
	b3337	bfd	bacterioferritin-associated ferredoxin
	b3336	bfr	bacterioferrin
Position: -103 Score: 4.6 Sequence: AATAATGATTACCATTCCC Locus tag: b1452 Name: yncE Funciton: putative receptor, ATP binding
	b1452	yncE	putative receptor, ATP binding
Position: -99 Score: 4.7 Sequence: GGCATTGATAATCATTTTC Position: -93 Score: 5 Sequence: GATAATCATTTTCAATATC Locus tag: b3908 Name: sodA Funciton: manganese/iron superoxide dismutase
	b3908	sodA	manganese/iron superoxide dismutase
Position: -163 Score: 4.6 Sequence: AATAATGCTTCTCATTTTC Position: -48 Score: 5 Sequence: ATAAATGATAATCATTATT Locus tag: b0593 Name: entC Funciton: isochorismate synthetase, siderophore biosynthesis Locus tag: b0594 Name: entE Funciton: 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase complex Locus tag: b0595 Name: entB Funciton: enterobactin synthetase component B (isochorismatase) Locus tag: b0596 Name: entA Funciton: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, enterochelin biosynthesis Locus tag: b0597 Name: ybdB Funciton: putative protein PaaI, possibly involved in aromatic compounds catabolism
	b0593	entC	isochorismate synthetase, siderophore biosynthesis
	b0594	entE	2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase complex
	b0595	entB	enterobactin synthetase component B (isochorismatase)
	b0596	entA	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, enterochelin biosynthesis
	b0597	ybdB	putative protein PaaI, possibly involved in aromatic compounds catabolism
Position: -68 Score: 4.7 Sequence: GAATTTGATAATCATTCTC Position: -62 Score: 4.2 Sequence: GATAATCATTCTCGTTTGG Locus tag: b2392 Name: mntH Funciton: Mn2+/Fe2+ transporter, NRAMP family
	b2392	mntH	Mn2+/Fe2+ transporter, NRAMP family
Position: -83 Score: 4.9 Sequence: TATAATGATACGCATTATC Locus tag: b0683 Name: fur Funciton: ferric uptake transcription regulator
	b0683	fur	ferric uptake transcription regulator
Position: -245 Score: 4.7 Sequence: GGTAATGAGAATAATTAAC Locus tag: b1243 Name: oppA Funciton: oligopeptide ABC transporter; periplasmic binding protein Locus tag: b1244 Name: oppB Funciton: oligopeptide ABC transporter, permease protein Locus tag: b1245 Name: oppC Funciton: oligopeptide ABC transporter, permease protein Locus tag: b1246 Name: oppD Funciton: oligopeptide ABC transporter, ATP-binding protein Locus tag: b1247 Name: oppF Funciton: oligopeptide ABC transporter, ATP-binding protein
	b1243	oppA	oligopeptide ABC transporter; periplasmic binding protein
	b1244	oppB	oligopeptide ABC transporter, permease protein
	b1245	oppC	oligopeptide ABC transporter, permease protein
	b1246	oppD	oligopeptide ABC transporter, ATP-binding protein
	b1247	oppF	oligopeptide ABC transporter, ATP-binding protein
Position: -71 Score: 4.2 Sequence: ATGATTAACAATCATTATC Position: -65 Score: 4.6 Sequence: AACAATCATTATCATTTGC Locus tag: b3070 Name: yqjH Funciton: FAD-binding 9, siderophore-interacting domain protein
	b3070	yqjH	FAD-binding 9, siderophore-interacting domain protein
Position: -201 Score: 4.3 Sequence: TGGATTGATAATTGTTATC Position: -195 Score: 4.4 Sequence: GATAATTGTTATCGTTTGC Locus tag: b2155 Name: cirA Funciton: TonB-dependent ferric iron-catecholate receptor
	b2155	cirA	TonB-dependent ferric iron-catecholate receptor
Position: -82 Score: 4.1 Sequence: AGTAATGAGAACGACTATC Locus tag: b3006 Name: exbB Funciton: TonB-dependent siderophore transporter component ExbB Locus tag: b3005 Name: exbD Funciton: TonB-dependent siderophore transporter component ExbD
	b3006	exbB	TonB-dependent siderophore transporter component ExbB
	b3005	exbD	TonB-dependent siderophore transporter component ExbD
Position: -4 Score: 4.9 Sequence: TATAATGATACGCATTATC Locus tag: b4637 Name: uof Funciton: ryhB-regulated fur leader peptide
	b4637	uof	ryhB-regulated fur leader peptide

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of Fur in Escherichia coli str. K-12 substr. MG1655

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --