Regulog Rex - Staphylococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	Rex
Regulation mode:	repressor
Biological process:	Energy metabolism
Effector:	NADH
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 74 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By trascription factor - Rex
By TF family - Rex
By effector - NADH
By pathway - Energy metabolism

Statistics of regulated genes
Genome	Genes	Operons
Staphylococcus aureus subsp. aureus N315	33	17
Staphylococcus capitis SK14	24	10
Staphylococcus epidermidis ATCC 12228	27	12
Staphylococcus carnosus subsp. carnosus TM300	14	7
Staphylococcus haemolyticus JCSC1435	22	11
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	7	6
Macrococcus caseolyticus JCSC5402	17	5

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
vicR	* Staphylococcus aureus subsp. aureus N315 Site: position = -79 score = 4.88934 sequence = CTGTGATTTTTTACACAA Gene: SA0017: cell wall homeostasis regulation two-component system, response regulator	Staphylococcus capitis SK14 Gene: STACA0001_1355: cell wall homeostasis regulation two-component system, response regulator	Staphylococcus epidermidis ATCC 12228 Gene: SE0018: cell wall homeostasis regulation two-component system, response regulator	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2456: cell wall homeostasis regulation two-component system, response regulator	Staphylococcus haemolyticus JCSC1435 Gene: SH0017: cell wall homeostasis regulation two-component system, response regulator	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0021: cell wall homeostasis regulation two-component system, response regulator	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0021: cell wall homeostasis regulation two-component system, response regulator	cell wall homeostasis regulation two-component system, response regulator
vicK	Staphylococcus aureus subsp. aureus N315 Gene: SA0018: cell wall homeostasis regulation two-component system, sensor kinase	Staphylococcus capitis SK14 Gene: STACA0001_1354: cell wall homeostasis regulation two-component system, sensor kinase	Staphylococcus epidermidis ATCC 12228 Gene: SE0019: cell wall homeostasis regulation two-component system, sensor kinase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2455: cell wall homeostasis regulation two-component system, sensor kinase	Staphylococcus haemolyticus JCSC1435 Gene: SH0018: cell wall homeostasis regulation two-component system, sensor kinase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0022: cell wall homeostasis regulation two-component system, sensor kinase	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0022: cell wall homeostasis regulation two-component system, sensor kinase	cell wall homeostasis regulation two-component system, sensor kinase

CRON 2.
srrA	* Staphylococcus aureus subsp. aureus N315 Site: position = -103 score = 5.63499 sequence = TTGAGAATTTTTTCACAA Gene: SA1323: Staphylococcal respiratory response protein SrrA	* Staphylococcus capitis SK14 Site: position = -106 score = 5.22335 sequence = TTGAGATTTTTTTCACAT Gene: STACA0001_1733: Staphylococcal respiratory response protein SrrA	* Staphylococcus epidermidis ATCC 12228 Site: position = -104 score = 4.9433 sequence = TTGATATTTTTTTCACAA Gene: SE1176: Staphylococcal respiratory response protein SrrA	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1118: Staphylococcal respiratory response protein SrrA	* Staphylococcus haemolyticus JCSC1435 Site: position = -101 score = 4.77667 sequence = TTGCTATTTTTTTCACAA Gene: SH1424: Staphylococcal respiratory response protein SrrA	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -105 score = 5.09306 sequence = ATGATAATTTTTTCACAA Gene: SSP1260: Staphylococcal respiratory response protein SrrA	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1138: Staphylococcal respiratory response protein SrrA	Staphylococcal respiratory response protein SrrA
srrB	Staphylococcus aureus subsp. aureus N315 Gene: SA1322: Staphylococcal respiratory response protein SrrB	Staphylococcus capitis SK14 Gene: STACA0001_1732: Staphylococcal respiratory response protein SrrB	Staphylococcus epidermidis ATCC 12228 Gene: SE1175: Staphylococcal respiratory response protein SrrB	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1117: Staphylococcal respiratory response protein SrrB	Staphylococcus haemolyticus JCSC1435 Gene: SH1425: Staphylococcal respiratory response protein SrrB	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1261: Staphylococcal respiratory response protein SrrB	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1137: Staphylococcal respiratory response protein SrrB	Staphylococcal respiratory response protein SrrB

CRON 3.
SA2268	* Staphylococcus aureus subsp. aureus N315 Site: position = -129 score = 5.7486 sequence = TTGTGAAATACATCACAA Gene: SA2268: conserved hypothetical protein	* Staphylococcus capitis SK14 Site: position = -94 score = 5.68161 sequence = TTGTGAAAAGTATCACAA Gene: STACA0001_1015: conserved hypothetical protein	* Staphylococcus epidermidis ATCC 12228 Site: position = -91 score = 5.68161 sequence = TTGTGAAATGTATCACAA Gene: SE2038: conserved hypothetical protein	Staphylococcus carnosus subsp. carnosus TM300	* Staphylococcus haemolyticus JCSC1435 Site: position = -87 score = 5.68161 sequence = TTGTGAAAAGTATCACAA Gene: SH0583: conserved hypothetical protein	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -107 score = 6.1004 sequence = TTGTGAAATTAATCACAA Gene: SSP0417: conserved hypothetical protein	Macrococcus caseolyticus JCSC5402	conserved hypothetical protein

CRON 4.
pflB	* Staphylococcus aureus subsp. aureus N315 Site: position = -96 score = 6.01941 sequence = ATGTGAAAAAAATCACAA Gene: SA0218: Pyruvate formate-lyase (EC 2.3.1.54)	Staphylococcus capitis SK14	* Staphylococcus epidermidis ATCC 12228 Site: position = -74 score = 5.83851 sequence = ATGTGAAATTAATCACAT Gene: SE0214: Pyruvate formate-lyase (EC 2.3.1.54)	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -93 score = 5.28459 sequence = AAGTGATTTTTTTCACAA Gene: Sca_2017: Pyruvate formate-lyase (EC 2.3.1.54)	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -74 score = 4.71535 sequence = TTGTGATACTTTTCACGT Gene: MCCL_0434: Pyruvate formate-lyase (EC 2.3.1.54)	Pyruvate formate-lyase (EC 2.3.1.54)
pflA	Staphylococcus aureus subsp. aureus N315 Gene: SA0219: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4)	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0215: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2016: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4)	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0433: Pyruvate formate-lyase activating enzyme (EC 1.97.1.4)	Pyruvate formate-lyase activating enzyme (EC 1.97.1.4)

CRON 5.
nirR	* Staphylococcus aureus subsp. aureus N315 Site: position = -64 score = 5.3317 sequence = ATGTGATTCTTTTCACAA Gene: SA2189: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	* Staphylococcus capitis SK14 Site: position = -64 score = 5.96315 sequence = ATGTGAATAAAATCACAA Gene: STACA0001_1076: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Staphylococcus epidermidis ATCC 12228 Gene: SE1979: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -64 score = 5.69577 sequence = TTGTGAATACATTCACAT Gene: Sca_1899: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Staphylococcus haemolyticus JCSC1435 Gene: SH0650: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -91 score = 5.77136 sequence = ATGTGAACATATTCACAA Gene: MCCL_1342: Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
sirA	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1898: syroheme synthase	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1341: syroheme synthase	syroheme synthase
nasD	Staphylococcus aureus subsp. aureus N315 Gene: SA2188: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)	Staphylococcus capitis SK14 Gene: STACA0001_1077: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)	* Staphylococcus epidermidis ATCC 12228 Site: position = -145 score = 5.59201 sequence = ATGTGAATTACATCACAA Gene: SE1978: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1897: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)	* Staphylococcus haemolyticus JCSC1435 Site: position = -141 score = 5.5677 sequence = TTGTGAAAATCATCACAT Gene: SH0651: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1340: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)	Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
nasE	Staphylococcus aureus subsp. aureus N315 Gene: SA2187: Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)	Staphylococcus capitis SK14 Gene: STACA0001_1078: Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)	Staphylococcus epidermidis ATCC 12228 Gene: SE1977: Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1896: Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)	Staphylococcus haemolyticus JCSC1435 Gene: SH0652: Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1339: Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)	Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)
nasF	Staphylococcus aureus subsp. aureus N315 Gene: SA2186: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Staphylococcus capitis SK14 Gene: STACA0001_1079: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Staphylococcus epidermidis ATCC 12228 Gene: SE1976: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1895: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Staphylococcus haemolyticus JCSC1435 Gene: SH0653: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1338: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)	Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)

CRON 6.
nirC	* Staphylococcus aureus subsp. aureus N315 Site: position = -72 score = 6.23263 sequence = TTGTGAAATTATTCACAA Gene: SA0293: Formate/nitrite family of transporters	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -75 score = 5.90045 sequence = TTGTGAAAGTATTCACAA Gene: Sca_1814: Formate/nitrite family of transporters	Staphylococcus haemolyticus JCSC1435	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -71 score = 6.23263 sequence = TTGTGAAAATATTCACAA Gene: SSP0590: Formate/nitrite family of transporters	Macrococcus caseolyticus JCSC5402	Formate/nitrite family of transporters

CRON 7.
narK	* Staphylococcus aureus subsp. aureus N315 Site: position = -168 score = 4.61555 sequence = ATGTTCACTTTTTCACAA Gene: SA2176: nitrate-nitrite antiporter	* Staphylococcus capitis SK14 Site: position = -156 score = 4.92023 sequence = ATGTTCATTTTTTCACAA Gene: STACA0001_1087: nitrate-nitrite antiporter	* Staphylococcus epidermidis ATCC 12228 Site: position = -149 score = 4.92023 sequence = ATGTTCATATTTTCACAA Gene: SE1968: nitrate-nitrite antiporter	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1887: nitrate-nitrite antiporter	* Staphylococcus haemolyticus JCSC1435 Site: position = -125 score = 4.92023 sequence = ATGTTCATTTTTTCACAA Gene: SH0661: nitrate-nitrite antiporter	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -73 score = 5.06421 sequence = ATGTTAAACTTATCACAA Gene: MCCL_0144: nitrate-nitrite antiporter	nitrate-nitrite antiporter

CRON 8.
narG	* Staphylococcus aureus subsp. aureus N315 Site: position = -107 score = 5.54698 sequence = TTGTGAAAAAATGTACAA Gene: SA2185: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	* Staphylococcus capitis SK14 Site: position = -89 score = 5.54698 sequence = TTGTGAAAAAATGTACAA Gene: STACA0001_1080: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	* Staphylococcus epidermidis ATCC 12228 Site: position = -86 score = 5.54698 sequence = TTGTGAAAAAATGTACAA Gene: SE1975: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1894: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	* Staphylococcus haemolyticus JCSC1435 Site: position = -91 score = 5.3469 sequence = ATGTGAAAAATTGTACAA Gene: SH0654: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -58 score = 5.42002 sequence = TTGTGAAAAGTTTCATAA Gene: MCCL_0136: Respiratory nitrate reductase alpha chain (EC 1.7.99.4)	Respiratory nitrate reductase alpha chain (EC 1.7.99.4)
narH	Staphylococcus aureus subsp. aureus N315 Gene: SA2184: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Staphylococcus capitis SK14 Gene: STACA0001_1081: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Staphylococcus epidermidis ATCC 12228 Gene: SE1974: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1893: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Staphylococcus haemolyticus JCSC1435 Gene: SH0655: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0137: Respiratory nitrate reductase beta chain (EC 1.7.99.4)	Respiratory nitrate reductase beta chain (EC 1.7.99.4)
narJ	Staphylococcus aureus subsp. aureus N315 Gene: SA2183: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Staphylococcus capitis SK14 Gene: STACA0001_1082: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Staphylococcus epidermidis ATCC 12228 Gene: SE1973: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1892: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Staphylococcus haemolyticus JCSC1435 Gene: SH0656: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0138: Respiratory nitrate reductase delta chain (EC 1.7.99.4)	Respiratory nitrate reductase delta chain (EC 1.7.99.4)
narI	Staphylococcus aureus subsp. aureus N315 Gene: SA2182: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Staphylococcus capitis SK14 Gene: STACA0001_1083: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Staphylococcus epidermidis ATCC 12228 Gene: SE1972: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1891: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Staphylococcus haemolyticus JCSC1435 Gene: SH0657: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0139: Respiratory nitrate reductase gamma chain (EC 1.7.99.4)	Respiratory nitrate reductase gamma chain (EC 1.7.99.4)
nreA	Staphylococcus aureus subsp. aureus N315 Gene: SA2181: control of nitrate reduction protein NreA	Staphylococcus capitis SK14 Gene: STACA0001_1084: control of nitrate reduction protein NreA	Staphylococcus epidermidis ATCC 12228 Gene: SE1971: control of nitrate reduction protein NreA	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1890: control of nitrate reduction protein NreA	Staphylococcus haemolyticus JCSC1435 Gene: SH0658: control of nitrate reduction protein NreA	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0140: control of nitrate reduction protein NreA	control of nitrate reduction protein NreA
nreB	Staphylococcus aureus subsp. aureus N315 Gene: SA2180: nitrate respiration regulation two-component system, sensor histidine kinase NreB	Staphylococcus capitis SK14 Gene: STACA0001_1085: nitrate respiration regulation two-component system, sensor histidine kinase NreB	Staphylococcus epidermidis ATCC 12228 Gene: SE1970: nitrate respiration regulation two-component system, sensor histidine kinase NreB	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1889: nitrate respiration regulation two-component system, sensor histidine kinase NreB	Staphylococcus haemolyticus JCSC1435 Gene: SH0659: nitrate respiration regulation two-component system, sensor histidine kinase NreB	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0141: nitrate respiration regulation two-component system, sensor histidine kinase NreB	nitrate respiration regulation two-component system, sensor histidine kinase NreB
nreC	Staphylococcus aureus subsp. aureus N315 Gene: SA2179: two-component response regulator NreC	Staphylococcus capitis SK14 Gene: STACA0001_1086: two-component response regulator NreC	Staphylococcus epidermidis ATCC 12228 Gene: SE1969: two-component response regulator NreC	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1888: two-component response regulator NreC	Staphylococcus haemolyticus JCSC1435 Gene: SH0660: two-component response regulator NreC	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0142: two-component response regulator NreC	two-component response regulator NreC

CRON 9.
lctP	* Staphylococcus aureus subsp. aureus N315 Site: position = -124 score = 5.95817 sequence = TTGTGAAAAAAATCACAT Gene: SA2156: L-lactate permease	* Staphylococcus capitis SK14 Site: position = -129 score = 5.88084 sequence = TTGTGAAAAAGTTCACAA Gene: STACA0001_1119: L-lactate permease	Staphylococcus epidermidis ATCC 12228 Gene: SE1945: L-lactate permease	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -85 score = 5.93381 sequence = ATGTGAATTAATTCACAT Gene: Sca_1867: L-lactate permease	* Staphylococcus haemolyticus JCSC1435 Site: position = -161 score = 5.88084 sequence = TTGTGAAAAAGTTCACAA Gene: SH0691: L-lactate permease	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -76 score = 6.25197 sequence = TTGTGAAAAAATTCACAA Gene: SSP0537: L-lactate permease	* Macrococcus caseolyticus JCSC5402 Site: position = -142 score = 6.1004 sequence = TTGTGAAAATAATCACAA Gene: MCCL_0162: L-lactate permease	L-lactate permease
ldh	2 Staphylococcus aureus subsp. aureus N315* Gene: SA2395: L-lactate dehydrogenase (EC:1.1.1.27) Site: position = -169 score = 6.01941 sequence = ATGTGAAATAAATCACAA Site: position = -227 score = 6.01941 sequence = ATGTGAAATAAATCACAA Gene: SA0232: L-lactate dehydrogenase (EC:1.1.1.27)	Staphylococcus capitis SK14 Gene: STACA0001_0896: L-lactate dehydrogenase (EC:1.1.1.27)	Staphylococcus epidermidis ATCC 12228 Gene: SE2145: L-lactate dehydrogenase (EC:1.1.1.27)	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -55 score = 5.46402 sequence = ATGTGAAATAAATCATAT Gene: Sca_1369: L-lactate dehydrogenase (EC:1.1.1.27)	Staphylococcus haemolyticus JCSC1435 Gene: SH0525: L-lactate dehydrogenase (EC:1.1.1.27)	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -55 score = 6.11974 sequence = TTGTGAAATAAATCACAA Site: position = -113 score = 6.11974 sequence = TTGTGAAATAAATCACAA Gene: SSP1001: L-lactate dehydrogenase (EC:1.1.1.27)	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0163: L-lactate dehydrogenase (EC:1.1.1.27)	L-lactate dehydrogenase (EC:1.1.1.27)

CRON 10.
hmp	* Staphylococcus aureus subsp. aureus N315 Site: position = -363 score = 5.6843 sequence = TTGTGATTTATTTCACAT Gene: SA0231: Nitric oxide dioxygenase (EC 1.14.12.17)	Staphylococcus capitis SK14 Gene: STACA0001_2302: Nitric oxide dioxygenase (EC 1.14.12.17)	Staphylococcus epidermidis ATCC 12228 Gene: SE0440: Nitric oxide dioxygenase (EC 1.14.12.17)	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_0683: Nitric oxide dioxygenase (EC 1.14.12.17)	* Staphylococcus haemolyticus JCSC1435 Site: position = -98 score = 5.69163 sequence = TTGTGAATTTAATTACAA Gene: SH1899: Nitric oxide dioxygenase (EC 1.14.12.17)	2 Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305* Site: position = -99 score = 5.94437 sequence = TTGTGAATTTTATCACAA Gene: SSP1728: Nitric oxide dioxygenase (EC 1.14.12.17) Gene: SSP2410: Nitric oxide dioxygenase (EC 1.14.12.17)	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0684: Nitric oxide dioxygenase (EC 1.14.12.17)	Nitric oxide dioxygenase (EC 1.14.12.17)

CRON 11.
frp	* Staphylococcus aureus subsp. aureus N315 Site: position = -185 score = 6.01998 sequence = TTGTGAAAAATATCACAA Gene: SA2311: NAD(P)H-flavin oxidoreductase	* Staphylococcus capitis SK14 Site: position = -197 score = 5.80069 sequence = TTGTGAAAGTTTTCACAA Gene: STACA0001_0985: NAD(P)H-flavin oxidoreductase	* Staphylococcus epidermidis ATCC 12228 Site: position = -164 score = 5.33824 sequence = ATGTGATTTAATTCACTA Site: position = -208 score = 4.86375 sequence = TAGTAAAAACATTCACAA Gene: SE2073: NAD(P)H-flavin oxidoreductase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1976: NAD(P)H-flavin oxidoreductase	* Staphylococcus haemolyticus JCSC1435 Site: position = -133 score = 5.64879 sequence = TTGTTAAAAAATTCACAT Site: position = -182 score = 6.17636 sequence = TTGTGAATTTATTCACAA Gene: SH0546: NAD(P)H-flavin oxidoreductase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0379: NAD(P)H-flavin oxidoreductase	Macrococcus caseolyticus JCSC5402	NAD(P)H-flavin oxidoreductase

CRON 12.
ddh	* Staphylococcus aureus subsp. aureus N315 Site: position = -39 score = 5.88279 sequence = TTGTGATATTTTTCACAA Gene: SA2312: D-lactate dehydrogenase (EC 1.1.1.28)	* Staphylococcus capitis SK14 Site: position = -119 score = 5.81384 sequence = TTGTGAAAACTTTCACAA Gene: STACA0001_0984: D-lactate dehydrogenase (EC 1.1.1.28)	* Staphylococcus epidermidis ATCC 12228 Site: position = -56 score = 4.88487 sequence = TTGTGAATGTTTTTACTA Site: position = -100 score = 5.46029 sequence = TAGTGAATTAAATCACAT Gene: SE2074: D-lactate dehydrogenase (EC 1.1.1.28)	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -81 score = 6.01479 sequence = TTGTGAATATATTCACAT Gene: Sca_2121: D-lactate dehydrogenase (EC 1.1.1.28)	* Staphylococcus haemolyticus JCSC1435 Site: position = -203 score = 5.48212 sequence = ATGTGAATTTTTTAACAA Site: position = -154 score = 6.1957 sequence = TTGTGAATAAATTCACAA Gene: SH0545: D-lactate dehydrogenase (EC 1.1.1.28)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	D-lactate dehydrogenase (EC 1.1.1.28)

CRON 13.
arcA	* Staphylococcus aureus subsp. aureus N315 Site: position = -79 score = 5.78224 sequence = ATGTGAATATAATCACAT Gene: SA2428: Arginine deiminase (EC 3.5.3.6)	* Staphylococcus capitis SK14 Site: position = -77 score = 5.88256 sequence = TTGTGAATATAATCACAT Gene: STACA0001_1845: Arginine deiminase (EC 3.5.3.6)	2 Staphylococcus epidermidis ATCC 12228* Site: position = -76 score = 5.49447 sequence = TTGTGAATTAAATCACAC Gene: SE0106: Arginine deiminase (EC 3.5.3.6) Site: position = -76 score = 4.76749 sequence = ATGTGATAATCATCACGA Gene: SE2217: Arginine deiminase (EC 3.5.3.6)	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -74 score = 5.53216 sequence = ATGTGATTTTAATCACAT Gene: Sca_2085: Arginine deiminase (EC 3.5.3.6)	* Staphylococcus haemolyticus JCSC1435 Site: position = -76 score = 5.51948 sequence = ATGTGAAAACAATCACAT Gene: SH0367: Arginine deiminase (EC 3.5.3.6)	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Arginine deiminase (EC 3.5.3.6)
arcB	Staphylococcus aureus subsp. aureus N315 Gene: SA2427: Ornithine carbamoyltransferase (EC 2.1.3.3)	Staphylococcus capitis SK14 Gene: STACA0001_1844: Ornithine carbamoyltransferase (EC 2.1.3.3)	2 Staphylococcus epidermidis ATCC 12228 Gene: SE0103: Ornithine carbamoyltransferase (EC 2.1.3.3) Gene: SE2216: Ornithine carbamoyltransferase (EC 2.1.3.3)	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Ornithine carbamoyltransferase (EC 2.1.3.3)
arcD	Staphylococcus aureus subsp. aureus N315 Gene: SA2426: Arginine/ornithine antiporter ArcD	Staphylococcus capitis SK14 Gene: STACA0001_1843: Arginine/ornithine antiporter ArcD	2 Staphylococcus epidermidis ATCC 12228 Gene: SE0105: Arginine/ornithine antiporter ArcD Gene: SE2215: Arginine/ornithine antiporter ArcD	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2084: Arginine/ornithine antiporter ArcD	Staphylococcus haemolyticus JCSC1435 Gene: SH0368: Arginine/ornithine antiporter ArcD	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Arginine/ornithine antiporter ArcD
arcC	Staphylococcus aureus subsp. aureus N315 Gene: SA2425: Carbamate kinase (EC 2.7.2.2)	Staphylococcus capitis SK14 Gene: STACA0001_1842: Carbamate kinase (EC 2.7.2.2)	Staphylococcus epidermidis ATCC 12228 Gene: SE0102: Carbamate kinase (EC 2.7.2.2)	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Carbamate kinase (EC 2.7.2.2)
arcR	Staphylococcus aureus subsp. aureus N315 Gene: SA2424: Transcriptional regulator ArcR essential for anaerobic expression of the ADI pathway, Crp/Fnr family	Staphylococcus capitis SK14 Gene: STACA0001_1841: Transcriptional regulator ArcR essential for anaerobic expression of the ADI pathway, Crp/Fnr family	2 Staphylococcus epidermidis ATCC 12228 Gene: SE0104: Transcriptional regulator ArcR essential for anaerobic expression of the ADI pathway, Crp/Fnr family Gene: SE2214: Transcriptional regulator ArcR essential for anaerobic expression of the ADI pathway, Crp/Fnr family	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2083: Transcriptional regulator ArcR essential for anaerobic expression of the ADI pathway, Crp/Fnr family	Staphylococcus haemolyticus JCSC1435 Gene: SH0369: Transcriptional regulator ArcR essential for anaerobic expression of the ADI pathway, Crp/Fnr family	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Transcriptional regulator ArcR essential for anaerobic expression of the ADI pathway, Crp/Fnr family

CRON 14.
ald1	* Staphylococcus aureus subsp. aureus N315 Site: position = -38 score = 6.23263 sequence = TTGTGAAATTATTCACAA Gene: SA1272: Alanine dehydrogenase (EC 1.4.1.1)	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0065: Alanine dehydrogenase (EC 1.4.1.1)	Alanine dehydrogenase (EC 1.4.1.1)

CRON 15.
adhE	* Staphylococcus aureus subsp. aureus N315 Site: position = -39 score = 6.25197 sequence = TTGTGAAATAATTCACAA Gene: SA0143: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	Staphylococcus capitis SK14	* Staphylococcus epidermidis ATCC 12228 Site: position = -38 score = 6.09594 sequence = TTGTGAATTATTTCACAA Gene: SE0506: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)

CRON 16.
adhB	Staphylococcus aureus subsp. aureus N315	* Staphylococcus capitis SK14 Site: position = -36 score = 6.23263 sequence = TTGTGAAAATATTCACAA Gene: STACA0001_0960: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	* Staphylococcus epidermidis ATCC 12228 Site: position = -37 score = 5.38239 sequence = TTGCGAAAAATTTCACAT Gene: SE2098: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Staphylococcus carnosus subsp. carnosus TM300	* Staphylococcus haemolyticus JCSC1435 Site: position = -38 score = 6.07106 sequence = TTGTGAAAATATTCACAT Gene: SH0522: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent

CRON 17.
adh1/adhB	* Staphylococcus aureus subsp. aureus N315 Site: position = -306 score = 6.03413 sequence = TTGTGAATTAATTCACAT Gene: SA0562: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0375: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Rex - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --