Regulog HcpR - Clostridia-1

Properties
Regulator type:	Transcription factor
Regulator family:	CRP
Regulation mode:	activator
Biological process:	Nitrosative stress response
Effector:	Nitric oxide
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 32 sites [see more]

Member of regulog collections

By taxonomy - Clostridia-1
By trascription factor - HcpR
By TF family - CRP
By effector - Nitric oxide
By pathway - Nitrosative stress response

Statistics of regulated genes
Genome	Genes	Operons
Clostridium acetobutylicum ATCC 824	8	6
Clostridium butyricum 5521	1	1
Clostridium beijerincki NCIMB 8052	5	4
Clostridium botulinum A str. ATCC 3502	6	5
Clostridium kluyveri DSM 555	3	3
Clostridium novyi NT	3	3
Clostridium perfringens ATCC 13124	3	2
Clostridium tetani E88	9	7

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
Cbei_4355	* Clostridium acetobutylicum ATCC 824 Site: position = -83 score = 5.91415 sequence = TAGTAACATAAGTTACAG Gene: CAC0362: Conserved protein	Clostridium butyricum 5521	* Clostridium beijerincki NCIMB 8052 Site: position = -82 score = 5.84437 sequence = TTGTAACTTTTGTTACAT Gene: Cbei_4355: Conserved protein	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	* Clostridium tetani E88 Site: position = -73 score = 5.37611 sequence = TCGTAACATACGTTACTT Gene: CTC02534: Conserved protein	Conserved protein

CRON 2.
hcpR	* Clostridium acetobutylicum ATCC 824 Site: position = -40 score = 5.91881 sequence = CAGTAACATATGTTACAC Gene: CAC0884: Nitric oxide-resposive transcriptional regulator HcpR, Crp family	Clostridium butyricum 5521 Gene: CBY_3934: Nitric oxide-resposive transcriptional regulator HcpR, Crp family	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0780: Nitric oxide-resposive transcriptional regulator HcpR, Crp family	* Clostridium botulinum A str. ATCC 3502 Site: position = -45 score = 5.9164 sequence = CTGTAACTAATGTTACCA Gene: CBO2923: Nitric oxide-resposive transcriptional regulator HcpR, Crp family	* Clostridium kluyveri DSM 555 Site: position = -67 score = 5.48446 sequence = CTGTAACTTACGTTACAC Gene: CKL_2420: Nitric oxide-resposive transcriptional regulator HcpR, Crp family	* Clostridium novyi NT Site: position = -63 score = 5.51741 sequence = ATGTAACCTAAGTTACCA Gene: NT01CX_0590: Nitric oxide-resposive transcriptional regulator HcpR, Crp family	Clostridium perfringens ATCC 13124 Gene: CPF_2845: Nitric oxide-resposive transcriptional regulator HcpR, Crp family	2 Clostridium tetani E88* Site: position = -20 score = 5.4024 sequence = CAGTAACCATAGTTACTA Gene: CTC00896: Nitric oxide-resposive transcriptional regulator HcpR, Crp family Gene: CTC01969: Nitric oxide-resposive transcriptional regulator HcpR, Crp family	Nitric oxide-resposive transcriptional regulator HcpR, Crp family

CRON 3.
CTC00897	Clostridium acetobutylicum ATCC 824	Clostridium butyricum 5521	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	* Clostridium tetani E88 Site: position = -98 score = 5.4024 sequence = TAGTAACTATGGTTACTG Gene: CTC00897: conserved protein, permease-related	conserved protein, permease-related
CTC00898	Clostridium acetobutylicum ATCC 824	Clostridium butyricum 5521	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium tetani E88 Gene: CTC00898: 4Fe-4S binding domain	4Fe-4S binding domain

CRON 4.
Cbei_3757	Clostridium acetobutylicum ATCC 824	Clostridium butyricum 5521	Clostridium beijerincki NCIMB 8052 Gene: Cbei_3757: hypothetical protein	* Clostridium botulinum A str. ATCC 3502 Site: position = -110 score = 5.72255 sequence = TAGTAACATTAGTTACTG Gene: CBO2926: hypothetical protein	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	* Clostridium tetani E88 Site: position = -108 score = 5.91415 sequence = TAGTAACATAAGTTACAG Gene: CTC00439: conserved protein	hypothetical protein

CRON 5.
hcp	2 Clostridium acetobutylicum ATCC 824* Site: position = -107 score = 5.80495 sequence = TAGTAACCAATGTTACAG Gene: CA_C3428: Hydroxylamine reductase (EC 1.7.-.-) Site: position = -88 score = 5.77642 sequence = AAGTAACAATTGTTACGG Gene: CA_C2750: Hydroxylamine reductase (EC 1.7.-.-)	Clostridium butyricum 5521	2 Clostridium beijerincki NCIMB 8052* Site: position = -126 score = 5.21415 sequence = TAGTAACGTGTGTTACAG Gene: Cbei_2276: Hydroxylamine reductase (EC 1.7.-.-) Site: position = -223 score = 5.48946 sequence = GCGTAACCATTGTTACAG Site: position = -128 score = 5.75574 sequence = TAGTAACGTATGTTACAG Gene: Cbei_1434: Hydroxylamine reductase (EC 1.7.-.-)	* Clostridium botulinum A str. ATCC 3502 Site: position = -122 score = 5.99654 sequence = TTGTAACATAGGTTACAG Gene: CBO2792: Hydroxylamine reductase (EC 1.7.-.-)	* Clostridium kluyveri DSM 555 Site: position = -100 score = 4.82942 sequence = TCGTATCCTAAGTTACCG Gene: CKL_0935: Hydroxylamine reductase (EC 1.7.-.-)	* Clostridium novyi NT Site: position = -100 score = 5.79192 sequence = TGGTAACATAAGTTACAT Gene: NT01CX_0591: Hydroxylamine reductase (EC 1.7.-.-)	* Clostridium perfringens ATCC 13124 Site: position = -141 score = 5.55949 sequence = AGGTAACTTTAGTTACCG Gene: CPF_2909: Hydroxylamine reductase (EC 1.7.-.-)	* Clostridium tetani E88 Site: position = -106 score = 6.12734 sequence = TTGTAACATTTGTTACCG Gene: CTC00410: Hydroxylamine reductase (EC 1.7.-.-)	Hydroxylamine reductase (EC 1.7.-.-)

CRON 6.
frdX	* Clostridium acetobutylicum ATCC 824 Site: position = -101 score = 5.91881 sequence = GTGTAACATATGTTACTG Gene: CAC0885: 4Fe-4S ferredoxin iron-sulfur binding domain protein	Clostridium butyricum 5521	Clostridium beijerincki NCIMB 8052	* Clostridium botulinum A str. ATCC 3502 Site: position = -77 score = 5.9164 sequence = TGGTAACATTAGTTACAG Gene: CBO2922: 4Fe-4S ferredoxin iron-sulfur binding domain protein	* Clostridium kluyveri DSM 555 Site: position = -74 score = 5.48446 sequence = GTGTAACGTAAGTTACAG Gene: CKL_2419: 4Fe-4S ferredoxin iron-sulfur binding domain protein	* Clostridium novyi NT Site: position = -89 score = 5.51741 sequence = TGGTAACTTAGGTTACAT Gene: NT01CX_0589: 4Fe-4S ferredoxin iron-sulfur binding domain protein	Clostridium perfringens ATCC 13124	* Clostridium tetani E88 Site: position = -93 score = 5.59866 sequence = ACGTAACATTCGTTACAG Gene: CTC01972: 4Fe-4S ferredoxin iron-sulfur binding domain protein	4Fe-4S ferredoxin iron-sulfur binding domain protein

CRON 7.
CAC0758	* Clostridium acetobutylicum ATCC 824 Site: position = -133 score = 4.62538 sequence = TCGTAACGAAGGATACCG Gene: CAC0758: no significant homology	Clostridium butyricum 5521	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium tetani E88	no significant homology
CAC0759	Clostridium acetobutylicum ATCC 824 Gene: CAC0759: Conserved protein	* Clostridium butyricum 5521 Site: position = -98 score = 6.18233 sequence = CTGTAACTTATGTTACAG Gene: CBY_3927: Conserved protein	* Clostridium beijerincki NCIMB 8052 Site: position = -178 score = 5.24286 sequence = TTGTATCATATGTTACGT Gene: Cbei_1845: Conserved protein	* Clostridium botulinum A str. ATCC 3502 Site: position = -143 score = 5.00786 sequence = GAGTAACATCCGTTACAG Gene: CBO1658: Conserved protein	Clostridium kluyveri DSM 555	Clostridium novyi NT	* Clostridium perfringens ATCC 13124 Site: position = -75 score = 5.85058 sequence = AGGTAACCTATGTTACAG Gene: CPF_1730: Conserved protein	* Clostridium tetani E88 Site: position = -79 score = 5.74629 sequence = TGGTAACTAATGTTACAT Gene: CTC01608: Conserved protein	Conserved protein
CAC2488	Clostridium acetobutylicum ATCC 824 Gene: CAC0760: Conserved protein	Clostridium butyricum 5521	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1846: Conserved protein	Clostridium botulinum A str. ATCC 3502 Gene: CBO1659: Conserved protein	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_1729: Conserved protein	Clostridium tetani E88 Gene: CTC01607: Conserved protein	Conserved protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog HcpR - Clostridia-1

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --