Regulog Fur - Clostridia-2

Properties
Regulator type:	Transcription factor
Regulator family:	FUR
Regulation mode:	repressor
Biological process:	Iron homeostasis
Effector:	Iron ion, (Fe2+)
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 24 sites [see more]

Member of regulog collections

By taxonomy - Clostridia-2
By trascription factor - FUR
By TF family - FUR
By effector - Iron ion, (Fe2+)
By pathway - Iron homeostasis

Statistics of regulated genes
Genome	Genes	Operons
Clostridium difficile 630	16	9
Clostridium bartlettii DSM 16795	12	5
Clostridium hiranonis DSM 13275	4	3

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes				Function

CRON 1.
zupT	* Clostridium difficile 630 Site: position = -38 score = 6.27902 sequence = AATGATAATCAATATCAAT Gene: CD1087: Metal transporter, ZIP family	Clostridium bartlettii DSM 16795	* Clostridium hiranonis DSM 13275 Site: position = -53 score = 5.3352 sequence = ATTAATATTCACTTTCATT Gene: CLOHIR_01757: Metal transporter, ZIP family	Metal transporter, ZIP family

CRON 2.
PF10087	* Clostridium difficile 630 Site: position = -37 score = 5.82234 sequence = AATGAAAATCAATATCAAA Site: position = -43 score = 5.61093 sequence = AATAATAATGAAAATCAAT Site: position = -106 score = 6.0324 sequence = AATGATAATTAATATCAAT Gene: CD2499: Uncharacterized protein conserved in bacteria (DUF2325)	* Clostridium bartlettii DSM 16795 Site: position = -163 score = 5.35407 sequence = ACTGATAAATATTATCAAT Site: position = -103 score = 6.03211 sequence = AATGATAATCAGTATCATT Gene: CLOBAR_01156: Uncharacterized protein conserved in bacteria (DUF2325)	* Clostridium hiranonis DSM 13275 Site: position = -71 score = 5.48628 sequence = CATAATAATGATTATCAAA Gene: CLOHIR_00610: Uncharacterized protein conserved in bacteria (DUF2325)	Uncharacterized protein conserved in bacteria (DUF2325)

CRON 3.
fur	* Clostridium difficile 630 Site: position = -41 score = 5.33967 sequence = TTTAATAAAGATTATCAAT Gene: CD1287: Transcriptional regulator for iron transport and metabolism, Fur family	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02180: Transcriptional regulator for iron transport and metabolism, Fur family	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01204: Transcriptional regulator for iron transport and metabolism, Fur family	Transcriptional regulator for iron transport and metabolism, Fur family

CRON 4.
CD1485	* Clostridium difficile 630 Site: position = -37 score = 5.43028 sequence = CTTGATATTAATTTTCATT Site: position = -74 score = 6.27902 sequence = ATTGATATTGATTATCATT Gene: CD1485: Conserved protein	* Clostridium bartlettii DSM 16795 Site: position = -35 score = 5.18968 sequence = GGTGATAATAATTATCAAT Site: position = -67 score = 5.44971 sequence = AATTATTATCATTATCAAT Gene: CLOBAR_01994: Conserved protein	Clostridium hiranonis DSM 13275	Conserved protein

CRON 5.
fhuD	* Clostridium difficile 630 Site: position = -50 score = 5.82006 sequence = TATGATAATCAATATCATA Gene: CD2878: Ferrichrome-binding protein	* Clostridium bartlettii DSM 16795 Site: position = -41 score = 6.09069 sequence = ATTGATAATCATTATTAAT Gene: CLOBAR_00861: Ferrichrome-binding protein	Clostridium hiranonis DSM 13275	Ferrichrome-binding protein
fhuB	Clostridium difficile 630 Gene: CD2877: Ferrichrome transport system permease protein FhuB (TC 3.A.1.14.3)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00860: Ferrichrome transport system permease protein FhuB (TC 3.A.1.14.3)	Clostridium hiranonis DSM 13275	Ferrichrome transport system permease protein FhuB (TC 3.A.1.14.3)
fhuG	Clostridium difficile 630 Gene: CD2876: Ferrichrome ABC transporter permease	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00859: Ferrichrome ABC transporter permease	Clostridium hiranonis DSM 13275	Ferrichrome ABC transporter permease
fhuC	Clostridium difficile 630 Gene: CD2875: Ferrichrome transport ATP-binding protein FhuC (TC 3.A.1.14.3)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00858: Ferrichrome transport ATP-binding protein FhuC (TC 3.A.1.14.3)	Clostridium hiranonis DSM 13275	Ferrichrome transport ATP-binding protein FhuC (TC 3.A.1.14.3)

CRON 6.
CD1647	* Clostridium difficile 630 Site: position = -91 score = 5.30012 sequence = ATTGACAATGATAATTATT Site: position = -85 score = 5.26344 sequence = AATGATAATTATTATTGAT Site: position = -50 score = 6.02653 sequence = AATGATAATAATTTTCATT Gene: CD1647: Iron compound ABC uptake transporter permease protein	* Clostridium bartlettii DSM 16795 Site: position = -115 score = 5.58085 sequence = AATGATAATCGTTATCATG Gene: CLOBAR_00960: Iron compound ABC uptake transporter permease protein	Clostridium hiranonis DSM 13275	Iron compound ABC uptake transporter permease protein
CD1648	Clostridium difficile 630 Gene: CD1648: Iron compound ABC uptake transporter permease protein	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00959: Iron compound ABC uptake transporter permease protein	Clostridium hiranonis DSM 13275	Iron compound ABC uptake transporter permease protein
CD1649	Clostridium difficile 630 Gene: CD1649: Iron compound ABC uptake transporter ATP-binding protein	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00958: Iron compound ABC uptake transporter ATP-binding protein	Clostridium hiranonis DSM 13275	Iron compound ABC uptake transporter ATP-binding protein
CD1650	Clostridium difficile 630 Gene: CD1650: Iron compound ABC uptake transporter substrate-binding protein	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00957: Iron compound ABC uptake transporter substrate-binding protein	Clostridium hiranonis DSM 13275	Iron compound ABC uptake transporter substrate-binding protein

CRON 7.
PF11449	* Clostridium difficile 630 Site: position = -71 score = 6.23294 sequence = ATTGATATTGATTATCAAT Gene: CD1819: Predicted manganese transporter, 11 TMS	Clostridium bartlettii DSM 16795	Clostridium hiranonis DSM 13275	Predicted manganese transporter, 11 TMS

CRON 8.
feoA	2 Clostridium difficile 630* Site: position = -33 score = 5.97455 sequence = TTTGATAATGATTTTCATT Gene: CD1745A: Ferrous iron transport protein A Site: position = -33 score = 5.71828 sequence = AGTGATAATGAATTTCATT Gene: CD3273: Ferrous iron transport protein A	* Clostridium bartlettii DSM 16795 Site: position = -30 score = 5.66426 sequence = TATGAAAATGAATTTCATT Gene: CLOBAR_00324: Ferrous iron transport protein A	* Clostridium hiranonis DSM 13275 Site: position = -39 score = 6.07486 sequence = ATTGATAATGAATTTCATT Gene: CLOHIR_00731: Ferrous iron transport protein A	Ferrous iron transport protein A
feoB	Clostridium difficile 630 Gene: CD3274: Ferrous iron transport protein B	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00323: Ferrous iron transport protein B	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00730: Ferrous iron transport protein B	Ferrous iron transport protein B

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Fur - Clostridia-2

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --