Regulog NrtR - Clostridia-1

Properties
Regulator type:	Transcription factor
Regulator family:	NrtR
Regulation mode:	repressor
Biological process:	NAD biosynthesis
Effector:	Adenosine diphosphate ribose
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 6 sites [see more]

Member of regulog collections

By trascription factor - NrtR
By taxonomy - Clostridia-1
By TF family - NrtR
By effector - Adenosine diphosphate ribose
By pathway - NAD biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Clostridium acetobutylicum ATCC 824	6	2
Clostridium beijerincki NCIMB 8052	2	1
Clostridium botulinum A str. ATCC 3502
Clostridium butyricum 5521
Clostridium kluyveri DSM 555
Clostridium novyi NT
Clostridium perfringens ATCC 13124
Clostridium tetani E88

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
nrtR	* Clostridium acetobutylicum ATCC 824 Site: position = -75 score = 6.31036 sequence = TTTGTATCAAAATGATGCTAA Site: position = -53 score = 5.55685 sequence = ATAGTTTTAATATGATACAAA Gene: CAC1777: Nudix-related transcriptional regulator NrtR	* Clostridium beijerincki NCIMB 8052 Site: position = -69 score = 5.64995 sequence = ATAGAATCAAATTGATATTAT Gene: Cbei_2075: Nudix-related transcriptional regulator NrtR	Clostridium botulinum A str. ATCC 3502	Clostridium butyricum 5521	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Nudix-related transcriptional regulator NrtR
prs	Clostridium acetobutylicum ATCC 824	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2076: Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)	Clostridium botulinum A str. ATCC 3502	Clostridium butyricum 5521	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)
pncA	Clostridium acetobutylicum ATCC 824 Gene: CAC1778: Nicotinamidase (EC 3.5.1.19)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2077: Nicotinamidase (EC 3.5.1.19)	Clostridium botulinum A str. ATCC 3502 Gene: CBO1134: Nicotinamidase (EC 3.5.1.19)	Clostridium butyricum 5521 Gene: CBY_1219: Nicotinamidase (EC 3.5.1.19)	Clostridium kluyveri DSM 555 Gene: CKL_2731: Nicotinamidase (EC 3.5.1.19)	Clostridium novyi NT Gene: NT01CX_2341: Nicotinamidase (EC 3.5.1.19)	Clostridium perfringens ATCC 13124 Gene: CPF_0569: Nicotinamidase (EC 3.5.1.19)	Clostridium tetani E88 Gene: CTC00699: Nicotinamidase (EC 3.5.1.19)	Nicotinamidase (EC 3.5.1.19)

CRON 2.
CAC1779	* Clostridium acetobutylicum ATCC 824 Site: position = -169 score = 4.93426 sequence = TTAGCTTTATTTTTATACAAA Site: position = -102 score = 6.49231 sequence = TTTGTATCATATTGGTACAAA Site: position = -39 score = 6.18943 sequence = TTTGTATCAATATAGTACAAA Gene: CAC1779: hypothetical protein	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium butyricum 5521	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium tetani E88	hypothetical protein
pncB	Clostridium acetobutylicum ATCC 824 Gene: CAC1780: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium butyricum 5521	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Nicotinate phosphoribosyltransferase (EC 2.4.2.11)
nadD	Clostridium acetobutylicum ATCC 824 Gene: CAC1781: Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18)	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium butyricum 5521	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18)
nadE	Clostridium acetobutylicum ATCC 824 Gene: CAC1782: NAD synthetase (EC 6.3.1.5)	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium butyricum 5521	Clostridium kluyveri DSM 555	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium tetani E88	NAD synthetase (EC 6.3.1.5)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NrtR - Clostridia-1

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --