Regulog MetJ - Psychromonadaceae/Aeromonadales
| Regulator type: | Transcription factor |
| Regulator family: | MetJ |
| Regulation mode: | repressor |
| Biological process: | Methionine metabolism; Methionine biosynthesis |
| Effector: | S-adenosylmethionine |
| Phylum: | Proteobacteria/Gamma |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Psychromonadaceae/Aeromonadales
- By trascription factor - MetJ
- By TF family - MetJ
- By effector - S-adenosylmethionine
- By pathway - Methionine metabolism
- By pathway - Methionine biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Psychromonas ingrahamii 37 | 6 | 4 |
| Psychromonas sp. CNPT3 | 7 | 5 |
| Moritella sp. PE36 | 11 | 8 |
| Aeromonas hydrophila subsp. hydrophila ATCC 7966 | 18 | 14 |
| Aeromonas salmonicida subsp. salmonicida A449 | 19 | 14 |
| Tolumonas auensis DSM 9187 | 11 | 7 |
| Genes | Function | ||||||
|---|---|---|---|---|---|---|---|
| CRON 1. | |||||||
| metA |
*
Psychromonas ingrahamii 37 Site: position = -52 score = 6.75022 sequence = AGACTTCT-(0)-GGATGTCC Gene: Ping_0112: Homoserine O-succinyltransferase (EC 2.3.1.46) |
|
*
Moritella sp. PE36 Site: position = -168 score = 6.58391 sequence = AGACTTCT-(0)-GGATGGCT Gene: PE36_00544: Homoserine O-succinyltransferase (EC 2.3.1.46) |
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -42 score = 5.61069 sequence = GGATGTCC-(0)-AGACATAT Site: position = -50 score = 5.80224 sequence = AGGCTTCT-(0)-GGATGTCC Gene: AHA_0489: Homoserine O-succinyltransferase (EC 2.3.1.46) |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -50 score = 5.80224 sequence = AGGCTTCT-(0)-GGATGTCC Site: position = -42 score = 5.61069 sequence = GGATGTCC-(0)-AGACATAT Gene: ASA_3695: Homoserine O-succinyltransferase (EC 2.3.1.46) |
*
Tolumonas auensis DSM 9187 Site: position = -49 score = 5.42751 sequence = AGATTTCC-(0)-GGATGTCC Site: position = -41 score = 6.00913 sequence = GGATGTCC-(0)-AGACGTTT Gene: Tola_2128: Homoserine O-succinyltransferase (EC 2.3.1.46) |
Homoserine O-succinyltransferase (EC 2.3.1.46) |
| metH |
Gene: Ping_0113: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) |
|
Gene: PE36_00549: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) |
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -79 score = 5.9753 sequence = AGACGGCT-(0)-AGATTTCC Site: position = -87 score = 6.07243 sequence = AGACAGAT-(0)-AGACGGCT Gene: AHA_0432: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -82 score = 5.9753 sequence = AGACGGCT-(0)-AGATTTCC Site: position = -90 score = 5.69906 sequence = GGACAGAT-(0)-AGACGGCT Gene: ASA_3912: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) |
Gene: Tola_2127: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) |
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) |
| CRON 2. | |||||||
| metR |
Gene: Ping_1476: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
|
*
Moritella sp. PE36 Site: position = -139 score = 5.67841 sequence = AGACGCTT-(0)-AGCTGTTT Site: position = -131 score = 6.19707 sequence = AGCTGTTT-(0)-AGATGGCT Gene: PE36_01280: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -134 score = 6.36387 sequence = AGCCATCC-(0)-AGATGTTT Site: position = -126 score = 6.03881 sequence = AGATGTTT-(0)-ACACATCC Gene: AHA_1955: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -182 score = 5.9905 sequence = GGCCATCC-(0)-AGATGTTT Site: position = -174 score = 6.03881 sequence = AGATGTTT-(0)-ACACATCC Gene: ASA_2339: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
*
Tolumonas auensis DSM 9187 Site: position = -96 score = 6.22079 sequence = GGATGTTT-(0)-AGATGTCC Site: position = -88 score = 5.62542 sequence = AGATGTCC-(0)-GGATGTTT Gene: Tola_2943: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
| CRON 3. | |||||||
| metT |
|
|
|
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -138 score = 6.28071 sequence = ATCCATCT-(0)-GGACGGCT Gene: AHA_2726: Methionine transporter MetT, NhaC antiporter family |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -141 score = 6.91006 sequence = ATCCGTCT-(0)-GGACGTCT Gene: ASA_1644: Methionine transporter MetT, NhaC antiporter family |
|
Methionine transporter MetT, NhaC antiporter family |
| CRON 4. | |||||||
| PCNPT3_05874 |
|
*
Psychromonas sp. CNPT3 Site: position = -104 score = 6.30866 sequence = AGACGTGT-(0)-AAACGGTT Gene: PCNPT3_05874: Homoserine/homoserine lactone efflux protein |
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|
|
|
Homoserine/homoserine lactone efflux protein |
| CRON 5. | |||||||
| metE |
Gene: Ping_3386: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
|
*
Moritella sp. PE36 Site: position = -80 score = 5.73871 sequence = AAACAGCT-(0)-AAGCGTCT Site: position = -88 score = 7.00963 sequence = AGCCATCT-(0)-AAACAGCT Gene: PE36_01285: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -55 score = 6.2282 sequence = AAACATCT-(0)-GGATGGCT Site: position = -63 score = 6.10224 sequence = GGATGTGT-(0)-AAACATCT Gene: AHA_1956: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -64 score = 5.92072 sequence = AAACATCT-(0)-GGATGGCC Site: position = -72 score = 6.10224 sequence = GGATGTGT-(0)-AAACATCT Gene: ASA_2338: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
*
Tolumonas auensis DSM 9187 Site: position = -37 score = 6.11966 sequence = AAACATCC-(0)-GGACATCT Site: position = -29 score = 7.03335 sequence = GGACATCT-(0)-AAACATCC Site: position = -45 score = 6.43278 sequence = AGCCATGT-(0)-AAACATCC Gene: Tola_2944: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
| CRON 6. | |||||||
| metJ |
*
Psychromonas ingrahamii 37 Site: position = -85 score = 7.01143 sequence = AGACATCT-(0)-AGCCCTCT Gene: Ping_0060: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Psychromonas sp. CNPT3 Site: position = -88 score = 7.1292 sequence = AGACTTCT-(0)-AGAAGTCT Gene: PCNPT3_01448: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Moritella sp. PE36 Site: position = -98 score = 7.01936 sequence = AGACGTCT-(0)-AGAGCTCT Gene: PE36_14846: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -97 score = 7.09853 sequence = ACACCTCT-(0)-AGACGTCT Site: position = -89 score = 7.30654 sequence = AGACGTCT-(0)-AAATGGCT Gene: AHA_0588: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -97 score = 6.71242 sequence = ACACTTCT-(0)-GGACGTCT Site: position = -89 score = 6.93317 sequence = GGACGTCT-(0)-AAATGGCT Gene: ASA_3794: S-adenosylmethionine-responsive transcriptional repressor MetJ |
*
Tolumonas auensis DSM 9187 Site: position = -95 score = 6.71242 sequence = ACACTTCT-(0)-GGACGTCT Site: position = -87 score = 6.46798 sequence = GGACGTCT-(0)-ACATGGCT Gene: Tola_0127: S-adenosylmethionine-responsive transcriptional repressor MetJ |
S-adenosylmethionine-responsive transcriptional repressor MetJ |
| CRON 7. | |||||||
| metB |
|
|
|
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -127 score = 6.59521 sequence = AGACGTCT-(0)-AGAGGTGT Site: position = -135 score = 7.44957 sequence = AGCCATTT-(0)-AGACGTCT Gene: AHA_0589: Cystathionine gamma-synthase (EC 2.5.1.48) |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -222 score = 7.14209 sequence = AGCCATTT-(0)-AGACGTCC Site: position = -214 score = 5.92346 sequence = AGACGTCC-(0)-AGAAGTGT Gene: ASA_3795: Cystathionine gamma-synthase (EC 2.5.1.48) |
*
Tolumonas auensis DSM 9187 Site: position = -83 score = 6.80622 sequence = AGCCATGT-(0)-AGACGTCC Site: position = -75 score = 5.92346 sequence = AGACGTCC-(0)-AGAAGTGT Gene: Tola_0128: Cystathionine gamma-synthase (EC 2.5.1.48) |
Cystathionine gamma-synthase (EC 2.5.1.48) |
| metL |
|
|
*
Moritella sp. PE36 Site: position = -94 score = 6.94964 sequence = AGAGCTCT-(0)-AGACGTCT Gene: PE36_14841: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) |
Gene: AHA_0590: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) |
Gene: ASA_3796: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) |
Gene: Tola_0129: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) |
Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) |
| CRON 8. | |||||||
| metK |
*
Psychromonas ingrahamii 37 Site: position = -58 score = 6.28773 sequence = AGACGTCT-(0)-AGATGTAA Gene: Ping_3227: S-adenosylmethionine synthetase (EC 2.5.1.6) |
*
Psychromonas sp. CNPT3 Site: position = -58 score = 6.05696 sequence = AGCCGTCT-(0)-AGATGTAA Site: position = -42 score = 5.34208 sequence = GAACATCT-(0)-AAATCTAT Gene: PCNPT3_02861: S-adenosylmethionine synthetase (EC 2.5.1.6) |
*
Moritella sp. PE36 Site: position = -80 score = 6.26153 sequence = AGCCGTCT-(0)-AGATGTTA Site: position = -64 score = 5.60505 sequence = AAACTTCT-(0)-ACACATAT Gene: PE36_05218: S-adenosylmethionine synthetase (EC 2.5.1.6) |
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -90 score = 5.24261 sequence = GGACGTCC-(0)-AGATGTAG Gene: AHA_3124: S-adenosylmethionine synthetase (EC 2.5.1.6) |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -90 score = 5.24261 sequence = GGACGTCC-(0)-AGATGTAG Gene: ASA_1201: S-adenosylmethionine synthetase (EC 2.5.1.6) |
Gene: Tola_1255: S-adenosylmethionine synthetase (EC 2.5.1.6) |
S-adenosylmethionine synthetase (EC 2.5.1.6) |
| CRON 9. | |||||||
| mmuM |
|
|
|
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -81 score = 7.19117 sequence = AGCCGTCT-(0)-AGATGTTT Site: position = -89 score = 5.89521 sequence = GGCATTCT-(0)-AGCCGTCT Gene: AHA_2807: Homocysteine S-methyltransferase (EC 2.1.1.10) |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -170 score = 7.48343 sequence = AGCCATCT-(0)-AAACATCT Site: position = -162 score = 6.11389 sequence = AAACATCT-(0)-ATATGTTT Gene: ASA_1525: Homocysteine S-methyltransferase (EC 2.1.1.10) |
|
Homocysteine S-methyltransferase (EC 2.1.1.10) |
| mmuP |
|
|
Gene: PE36_07936: S-methylmethionine transporter |
Gene: AHA_2806: S-methylmethionine transporter |
Gene: ASA_1526: S-methylmethionine transporter |
|
S-methylmethionine transporter |
| CRON 10. | |||||||
| metF |
|
|
*
Moritella sp. PE36 Site: position = -38 score = 5.57701 sequence = AGAGGTAC-(0)-GGACGTCT Site: position = -30 score = 7.49638 sequence = GGACGTCT-(0)-AAACATCT Gene: PE36_14836: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -59 score = 6.89051 sequence = AGACGTCC-(0)-AAACATCC Site: position = -67 score = 7.5284 sequence = AGACGTTT-(0)-AGACGTCC Gene: AHA_3949: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
|
*
Tolumonas auensis DSM 9187 Site: position = -81 score = 7.19799 sequence = AGACGTCC-(0)-AAACATCT Site: position = -89 score = 6.99949 sequence = GGACATTT-(0)-AGACGTCC Gene: Tola_0061: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
| CRON 11. | |||||||
| ASA_2534 |
Gene: Ping_1994: Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) |
Gene: PCNPT3_07210: Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) |
Gene: PE36_02409: Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) |
Gene: AHA_2683: Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -142 score = 6.29241 sequence = AGGCATCT-(0)-GAACATCT Gene: ASA_2534: Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) |
Gene: Tola_1572: Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) |
Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290) |
| asd |
Gene: Ping_1993: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: PCNPT3_07215: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: PE36_02404: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: AHA_2682: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: ASA_2533: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: Tola_1571: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
| CRON 12. | |||||||
| metQ2 |
|
*
Psychromonas sp. CNPT3 Site: position = -95 score = 7.02622 sequence = AGACGTAT-(0)-GGACGTCT Site: position = -87 score = 7.03119 sequence = GGACGTCT-(0)-ACACATCT Gene: PCNPT3_10128: Methionine ABC transporter substrate-binding protein |
|
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -86 score = 6.37423 sequence = AGCCGTTT-(0)-GGATGGCT Gene: AHA_2685: Methionine ABC transporter substrate-binding protein |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -98 score = 6.37423 sequence = AGCCGTTT-(0)-GGATGGCT Gene: ASA_2536: Methionine ABC transporter substrate-binding protein |
|
Methionine ABC transporter substrate-binding protein |
| CRON 13. | |||||||
| metN |
*
Psychromonas ingrahamii 37 Site: position = -106 score = 7.24544 sequence = AGACGTCT-(0)-ATACGGCT Gene: Ping_3538: Methionine ABC transporter ATP-binding protein |
*
Psychromonas sp. CNPT3 Site: position = -51 score = 6.16699 sequence = AGATGTCT-(0)-TAATGTCT Site: position = -59 score = 7.72915 sequence = AGCCGTCT-(0)-AGATGTCT Gene: PCNPT3_08944: Methionine ABC transporter ATP-binding protein |
*
Moritella sp. PE36 Site: position = -136 score = 5.68359 sequence = GGCCGTCT-(0)-AGATGTAA Gene: PE36_21935: Methionine ABC transporter ATP-binding protein |
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -118 score = 6.61789 sequence = GGCCATCC-(0)-AGACATCT Site: position = -150 score = 7.21736 sequence = AGACGTCT-(0)-AGATGTAT Gene: AHA_0915: Methionine ABC transporter ATP-binding protein |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -150 score = 6.571 sequence = AGACGTCT-(0)-AGACGTAG Site: position = -118 score = 6.99126 sequence = AGCCATCC-(0)-AGACATCT Gene: ASA_3378: Methionine ABC transporter ATP-binding protein |
*
Tolumonas auensis DSM 9187 Site: position = -132 score = 6.017 sequence = AAACATCC-(0)-AAATGTCC Site: position = -140 score = 7.56226 sequence = AGACGTCT-(0)-AAACATCC Gene: Tola_0251: Methionine ABC transporter ATP-binding protein |
Methionine ABC transporter ATP-binding protein |
| metI |
Gene: Ping_3537: Methionine ABC transporter permease protein |
Gene: PCNPT3_08949: Methionine ABC transporter permease protein |
Gene: PE36_21940: Methionine ABC transporter permease protein |
Gene: AHA_0914: Methionine ABC transporter permease protein |
Gene: ASA_3379: Methionine ABC transporter permease protein |
Gene: Tola_0250: Methionine ABC transporter permease protein |
Methionine ABC transporter permease protein |
| metQ |
Gene: Ping_3536: Methionine ABC transporter substrate-binding protein |
Gene: PCNPT3_08954: Methionine ABC transporter substrate-binding protein |
Gene: PE36_21945: Methionine ABC transporter substrate-binding protein |
Gene: AHA_0913: Methionine ABC transporter substrate-binding protein |
Gene: ASA_3380: Methionine ABC transporter substrate-binding protein |
Gene: Tola_0249: Methionine ABC transporter substrate-binding protein |
Methionine ABC transporter substrate-binding protein |
| CRON 14. | |||||||
| btuB |
|
|
Gene: PE36_23785: TonB-dependent outer membrane transporter for vitamin B12 |
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -266 score = 6.07931 sequence = AGAAATCT-(0)-GGATGGCT Gene: AHA_0074: TonB-dependent outer membrane transporter for vitamin B12 |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -268 score = 6.07931 sequence = AGAAATCT-(0)-GGATGGCT Gene: ASA_0076: TonB-dependent outer membrane transporter for vitamin B12 |
|
TonB-dependent outer membrane transporter for vitamin B12 |
| CRON 15. | |||||||
| metY |
Gene: Ping_3644: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) |
|
|
*
Aeromonas hydrophila subsp. hydrophila ATCC 7966 Site: position = -54 score = 6.61403 sequence = GGACGTCT-(0)-ATCCATCT Gene: AHA_0506: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) |
*
Aeromonas salmonicida subsp. salmonicida A449 Site: position = -67 score = 6.61403 sequence = GGACGTCT-(0)-ATCCATCT Gene: ASA_3712: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) |
Gene: Tola_0169: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) |
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |