Regulog TPP - Streptomycetaceae

Properties
Regulator type:	RNA regulatory element
Name:	TPP
RFAM:	RF00059
Regulation mode:
Biological process:	Thiamine biosynthesis
Effector:	Thiamine pyrophosphate
Phylum:	Actinobacteria

Member of regulog collections

By taxonomy - Streptomycetaceae
By RNA motif - TPP
By effector - Thiamine pyrophosphate
By pathway - Thiamine biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Streptomyces griseus subsp. griseus NBRC 13350	7	3
Streptomyces scabiei 87.22	7	3
Streptomyces avermitilis MA-4680	9	4
Streptomyces coelicolor A3(2)	7	3

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes					Function

CRON 1.
thiO	* Streptomyces griseus subsp. griseus NBRC 13350 Site: position = -111 score = 54.48 sequence = GTAGAACACTCGCGG... Gene: SGR_5394: Glycine oxidase ThiO (EC 1.4.3.19)	* Streptomyces scabiei 87.22 Site: position = -110 score = 53.09 sequence = GTAGAGCACTCGCGG... Gene: SCAB_67741: Glycine oxidase ThiO (EC 1.4.3.19)	* Streptomyces avermitilis MA-4680 Site: position = -112 score = 54.26 sequence = GTAAAGCACTCGCGG... Gene: SAV_6095: Glycine oxidase ThiO (EC 1.4.3.19)	* Streptomyces coelicolor A3(2) Site: position = -108 score = 50.41 sequence = AAGGCACTCGCGGGA... Gene: SCO2107: Glycine oxidase ThiO (EC 1.4.3.19)	Glycine oxidase ThiO (EC 1.4.3.19)
thiS	Streptomyces griseus subsp. griseus NBRC 13350 Gene: SGR_5393: Sulfur carrier protein ThiS	Streptomyces scabiei 87.22 Gene: SCAB_67731: Sulfur carrier protein ThiS	Streptomyces avermitilis MA-4680 Gene: SAV_6094: Sulfur carrier protein ThiS	Streptomyces coelicolor A3(2) Gene: SCO2108: Sulfur carrier protein ThiS	Sulfur carrier protein ThiS
thiG	Streptomyces griseus subsp. griseus NBRC 13350 Gene: SGR_5392: Thiazole biosynthesis protein ThiG	Streptomyces scabiei 87.22 Gene: SCAB_67721: Thiazole biosynthesis protein ThiG	Streptomyces avermitilis MA-4680 Gene: SAV_6093: Thiazole biosynthesis protein ThiG	Streptomyces coelicolor A3(2) Gene: SCO2109: Thiazole biosynthesis protein ThiG	Thiazole biosynthesis protein ThiG

CRON 2.
thiB	* Streptomyces griseus subsp. griseus NBRC 13350 Site: position = -121 score = 49.1 sequence = CATATTCCGACAGGG... Gene: SGR_1857: Thiamin ABC transporter, substrate-binding component	* Streptomyces scabiei 87.22 Site: position = -188 score = 49.19 sequence = CATATTCCGACAGGG... Gene: SCAB_25941: Thiamin ABC transporter, substrate-binding component	* Streptomyces avermitilis MA-4680 Site: position = -187 score = 51.44 sequence = CATATTCCGACAGGG... Gene: SAV_2620: Thiamin ABC transporter, substrate-binding component	* Streptomyces coelicolor A3(2) Site: position = -184 score = 51.18 sequence = TATTCCGACAGGGGA... Gene: SCO5646: Thiamin ABC transporter, substrate-binding component	Thiamin ABC transporter, substrate-binding component
thiP	Streptomyces griseus subsp. griseus NBRC 13350 Gene: SGR_1856: Thiamin ABC transporter, transmembrane component	Streptomyces scabiei 87.22 Gene: SCAB_25931: Thiamin ABC transporter, transmembrane component	Streptomyces avermitilis MA-4680 Gene: SAV_2619: Thiamin ABC transporter, transmembrane component	Streptomyces coelicolor A3(2) Gene: SCO5647: Thiamin ABC transporter, transmembrane component	Thiamin ABC transporter, transmembrane component
thiQ	Streptomyces griseus subsp. griseus NBRC 13350 Gene: SGR_1855: Thiamin ABC transporter, ATPase component	Streptomyces scabiei 87.22 Gene: SCAB_25921: Thiamin ABC transporter, ATPase component	Streptomyces avermitilis MA-4680 Gene: SAV_2618: Thiamin ABC transporter, ATPase component	Streptomyces coelicolor A3(2) Gene: SCO5648: Thiamin ABC transporter, ATPase component	Thiamin ABC transporter, ATPase component

CRON 3.
cytX	Streptomyces griseus subsp. griseus NBRC 13350	Streptomyces scabiei 87.22	* Streptomyces avermitilis MA-4680 Site: position = -87 score = 65.95 sequence = CGTACCGGACACGGG... Gene: SAV_7206: Predicted hydroxymethylpyrimidine transporter CytX	Streptomyces coelicolor A3(2)	Predicted hydroxymethylpyrimidine transporter CytX
thiD	Streptomyces griseus subsp. griseus NBRC 13350 Gene: SGR_1917: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Streptomyces scabiei 87.22 Gene: SCAB_26491: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Streptomyces avermitilis MA-4680 Gene: SAV_7205: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Streptomyces coelicolor A3(2) Gene: SCO5563: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Phosphomethylpyrimidine kinase (EC 2.7.4.7)

CRON 4.
thiC	* Streptomyces griseus subsp. griseus NBRC 13350 Site: position = -127 score = 41.95 sequence = CCTTTGCACACGCGG... Gene: SGR_3653: Thiamin biosynthesis protein ThiC	* Streptomyces scabiei 87.22 Site: position = -148 score = 39.37 sequence = TTTGCACACGCGGGA... Gene: SCAB_46341: Thiamin biosynthesis protein ThiC	* Streptomyces avermitilis MA-4680 Site: position = -150 score = 39.87 sequence = CCTTTGCACACGCGG... Gene: SAV_4265: Thiamin biosynthesis protein ThiC	* Streptomyces coelicolor A3(2) Site: position = -54 score = 22.76 sequence = TGCGTCGACCGCCGA... Gene: SCO3928: Thiamin biosynthesis protein ThiC	Thiamin biosynthesis protein ThiC

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog TPP - Streptomycetaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --