Regulog SgaR - Streptococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	BglG
Regulation mode:	repressor
Biological process:	Ascorbate utilization
Effector:	HPr, phosphocarrier protein; SgaB, ascorbate-specific PTS system EIIB component
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 19 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By TF family - BglG
By effector - HPr, phosphocarrier protein
By effector - SgaB, ascorbate-specific PTS system EIIB component
By pathway - Ascorbate utilization

Statistics of regulated genes
Genome	Genes	Operons
Lactococcus lactis subsp. cremoris SK11
Lactococcus lactis subsp. lactis Il1403
Streptococcus agalactiae 2603V/R	7	2
Streptococcus dysgalactiae subsp. equisimilis GGS_124	7	2
Streptococcus equi subsp. zooepidemicus MGCS10565	7	2
Streptococcus gallolyticus UCN34	6	1
Streptococcus gordonii str. Challis substr. CH1
Streptococcus mitis B6	1	1
Streptococcus mutans UA159	7	2
Streptococcus pneumoniae TIGR4	1	1
Streptococcus pyogenes M1 GAS	9	2
Streptococcus sanguinis SK36	7	2
Streptococcus suis 05ZYH33	9	2
Streptococcus thermophilus CNRZ1066
Streptococcus uberis 0140J	8	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
sgaG	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	* Streptococcus agalactiae 2603V/R Site: position = -92 score = 5.43241 sequence = AACACATAAATGTGTG Gene: SAG1800: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -94 score = 5.52065 sequence = AACACAGAACTGTGTG Gene: SDEG_2006: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -92 score = 5.12759 sequence = AACACAAGAGTGTGTG Gene: Sez_0175: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	Streptococcus gallolyticus UCN34 Gene: GALLO_2113: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	Streptococcus gordonii str. Challis substr. CH1	* Streptococcus mitis B6 Site: position = -94 score = 5.73018 sequence = AACACAAACCTGTGTT Gene: smi_0226: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	* Streptococcus mutans UA159 Site: position = -100 score = 5.69961 sequence = AACACAAGCTTGTGTT Gene: SMU.290: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	* Streptococcus pneumoniae TIGR4 Site: position = -94 score = 5.73018 sequence = AACACAAACCTGTGTT Gene: SP_2031: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	* Streptococcus pyogenes M1 GAS Site: position = -95 score = 5.63428 sequence = AACACAGATCTGTGTG Gene: SPy0182: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	* Streptococcus sanguinis SK36 Site: position = -96 score = 5.7743 sequence = AACACAGACCTGTGTT Gene: SSA_2076: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	* Streptococcus suis 05ZYH33 Site: position = -92 score = 5.74373 sequence = AACACAAGCCTGTGTT Gene: SSU05_2055: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	Streptococcus thermophilus CNRZ1066	* Streptococcus uberis 0140J Site: position = -92 score = 5.26506 sequence = AACACTTACATGTGTG Gene: SUB1720: Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)	Predicted L-ascorbate-6-phosphate lactonase (EC 3.1.1.-)

CRON 2.
sgaT	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	* Streptococcus agalactiae 2603V/R Site: position = -100 score = 4.22068 sequence = CACACTTAAGTGTGTA Gene: SAG1815: Ascorbate-specific PTS system, EIIC component	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -104 score = 5.03405 sequence = AACACTTCTTTGTGTG Gene: SDEG_2013: Ascorbate-specific PTS system, EIIC component	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -105 score = 5.36291 sequence = AACACATTACTGTGTG Gene: Sez_0168: Ascorbate-specific PTS system, EIIC component	* Streptococcus gallolyticus UCN34 Site: position = -100 score = 5.0476 sequence = CACACTTCCTTGTGTT Gene: GALLO_2127: Ascorbate-specific PTS system, EIIC component	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6 Gene: smi_0219: Ascorbate-specific PTS system, EIIC component	* Streptococcus mutans UA159 Site: position = -101 score = 5.26506 sequence = AACACTTGTATGTGTG Gene: SMU.270: Ascorbate-specific PTS system, EIIC component	Streptococcus pneumoniae TIGR4 Gene: SP_2038: Ascorbate-specific PTS system, EIIC component	* Streptococcus pyogenes M1 GAS Site: position = -110 score = 5.03405 sequence = AACACTTCTTTGTGTG Gene: SPy0174: Ascorbate-specific PTS system, EIIC component	* Streptococcus sanguinis SK36 Site: position = -99 score = 3.86453 sequence = AACAGTCGCCTGTGTA Gene: SSA_2093: Ascorbate-specific PTS system, EIIC component	* Streptococcus suis 05ZYH33 Site: position = -93 score = 5.21959 sequence = AACACAAGCCTGTGCT Gene: SSU05_2063: Ascorbate-specific PTS system, EIIC component	Streptococcus thermophilus CNRZ1066	* Streptococcus uberis 0140J Site: position = -105 score = 5.52065 sequence = AACACAGAACTGTGTG Gene: SUB1727: Ascorbate-specific PTS system, EIIC component	Ascorbate-specific PTS system, EIIC component
sgaB	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1814: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_2012: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0169: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Streptococcus gallolyticus UCN34 Gene: GALLO_2126: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6 Gene: smi_0220: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Streptococcus mutans UA159 Gene: SMU.271: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Streptococcus pneumoniae TIGR4 Gene: SP_2037: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Streptococcus pyogenes M1 GAS Gene: SPy0175: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Streptococcus sanguinis SK36 Gene: SSA_2092: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Streptococcus suis 05ZYH33 Gene: SSU05_2062: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB1726: Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)	Ascorbate-specific PTS system, EIIB component (EC 2.7.1.69)
sgaC	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1813: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_2011: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0170: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Streptococcus gallolyticus UCN34 Gene: GALLO_2125: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6 Gene: smi_0221: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Streptococcus mutans UA159 Gene: SMU.272: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Streptococcus pneumoniae TIGR4 Gene: SP_2036: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Streptococcus pyogenes M1 GAS Gene: SPy0176: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Streptococcus sanguinis SK36 Gene: SSA_2091: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Streptococcus suis 05ZYH33 Gene: SSU05_2061: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB1725: Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)	Ascorbate-specific PTS system, EIIA component (EC 2.7.1.-)
sgaH	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1812: 3-keto-L-gulonate 6-phosphate decarboxylase	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_2010: 3-keto-L-gulonate 6-phosphate decarboxylase	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0171: 3-keto-L-gulonate 6-phosphate decarboxylase	Streptococcus gallolyticus UCN34 Gene: GALLO_2124: 3-keto-L-gulonate 6-phosphate decarboxylase	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6 Gene: smi_0222: 3-keto-L-gulonate 6-phosphate decarboxylase	Streptococcus mutans UA159 Gene: SMU.273: 3-keto-L-gulonate 6-phosphate decarboxylase	Streptococcus pneumoniae TIGR4 Gene: SP_2035: 3-keto-L-gulonate 6-phosphate decarboxylase	Streptococcus pyogenes M1 GAS Gene: SPy0177: 3-keto-L-gulonate 6-phosphate decarboxylase	Streptococcus sanguinis SK36 Gene: SSA_2090: 3-keto-L-gulonate 6-phosphate decarboxylase	Streptococcus suis 05ZYH33 Gene: SSU05_2060: 3-keto-L-gulonate 6-phosphate decarboxylase	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB1724: 3-keto-L-gulonate 6-phosphate decarboxylase	3-keto-L-gulonate 6-phosphate decarboxylase
sgaU	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1811: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_2009: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0172: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	Streptococcus gallolyticus UCN34 Gene: GALLO_2123: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6 Gene: smi_0223: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	Streptococcus mutans UA159 Gene: SMU.274: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	Streptococcus pneumoniae TIGR4 Gene: SP_2034: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	Streptococcus pyogenes M1 GAS Gene: SPy0178: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	Streptococcus sanguinis SK36 Gene: SSA_2089: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	Streptococcus suis 05ZYH33 Gene: SSU05_2059: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB1723: L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)	L-xylulose 5-phosphate 3-epimerase (EC 5.1.3.-)
sgaE	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1810: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_2008: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0173: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	Streptococcus gallolyticus UCN34 Gene: GALLO_2122: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6 Gene: smi_0224: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	Streptococcus mutans UA159 Gene: SMU.275: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	Streptococcus pneumoniae TIGR4 Gene: SP_2033: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	Streptococcus pyogenes M1 GAS Gene: SPy0179: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	Streptococcus sanguinis SK36 Gene: SSA_2088: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	Streptococcus suis 05ZYH33 Gene: SSU05_2058: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB1722: L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)	L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4)
SAG1816	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_2057: Conserved hypothetical protein	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Conserved hypothetical protein
sgaR	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG1801: Ascorbate utilization transcriptional regulator SgaR, BglG family	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_2007: Ascorbate utilization transcriptional regulator SgaR, BglG family	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0174: Ascorbate utilization transcriptional regulator SgaR, BglG family	Streptococcus gallolyticus UCN34 Gene: GALLO_2121: Ascorbate utilization transcriptional regulator SgaR, BglG family	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6 Gene: smi_0225: Ascorbate utilization transcriptional regulator SgaR, BglG family	Streptococcus mutans UA159 Gene: SMU.289: Ascorbate utilization transcriptional regulator SgaR, BglG family	Streptococcus pneumoniae TIGR4 Gene: SP_2032: Ascorbate utilization transcriptional regulator SgaR, BglG family	Streptococcus pyogenes M1 GAS Gene: SPy0181: Ascorbate utilization transcriptional regulator SgaR, BglG family	Streptococcus sanguinis SK36 Gene: SSA_2078: Ascorbate utilization transcriptional regulator SgaR, BglG family	Streptococcus suis 05ZYH33 Gene: SSU05_2056: Ascorbate utilization transcriptional regulator SgaR, BglG family	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB1721: Ascorbate utilization transcriptional regulator SgaR, BglG family	Ascorbate utilization transcriptional regulator SgaR, BglG family
SPy0180	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4	Streptococcus pyogenes M1 GAS Gene: SPy0180: Hypothetical protein	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	Hypothetical protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog SgaR - Streptococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --