Regulog LacR - Lactobacillaceae

Properties
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:	repressor
Biological process:	Lactose utilization
Effector:	Lactose
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 11 sites [see more]

Member of regulog collections

By taxonomy - Lactobacillaceae
By TF family - LacI
By effector - Lactose
By pathway - Lactose utilization

Statistics of regulated genes
Genome	Genes	Operons
Lactobacillus acidophilus NCFM	1	1
Lactobacillus brevis ATCC 367
Lactobacillus casei ATCC 334
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus fermentum IFO 3956	3	2
Lactobacillus helveticus DPC 4571	1	1
Lactobacillus johnsonii NCC 533	3	2
Lactobacillus plantarum WCFS1	3	2
Lactobacillus reuteri JCM 1112	2	1
Lactobacillus rhamnosus GG
Lactobacillus sakei subsp. sakei 23K
Lactobacillus salivarius subsp. salivarius UCC118
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	3	2
Oenococcus oeni PSU-1
Pediococcus pentosaceus ATCC 25745

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
lacR	* Lactobacillus acidophilus NCFM Site: position = -65 score = 4.66551 sequence = GGAATTGAGTAAATATT Gene: LBA1465: Lactose utilization transcriptional regulator, LacI family	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	* Lactobacillus fermentum IFO 3956 Site: position = -185 score = 5.49547 sequence = GTTAATTAGTAAATATT Gene: LAF_0781: Lactose utilization transcriptional regulator, LacI family	* Lactobacillus helveticus DPC 4571 Site: position = -64 score = 5.29641 sequence = GGAATTTAGTAAATATT Gene: lhv_1547: Lactose utilization transcriptional regulator, LacI family	* Lactobacillus johnsonii NCC 533 Site: position = -152 score = 4.54057 sequence = ATAATTTACTCAAAAAT Gene: LJ0856: Lactose utilization transcriptional regulator, LacI family	* Lactobacillus plantarum WCFS1 Site: position = -155 score = 5.61286 sequence = AATAATTACTAAATATC Gene: lp_3470: Lactose utilization transcriptional regulator, LacI family	Lactobacillus reuteri JCM 1112 Gene: LAR_1034: Lactose utilization transcriptional regulator, LacI family	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -119 score = 5.35277 sequence = AAAAATTAGTAAATGAT Gene: LEUM_1063: Lactose utilization transcriptional regulator, LacI family	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Lactose utilization transcriptional regulator, LacI family

CRON 2.
lacS	Lactobacillus acidophilus NCFM Gene: LBA1463: Lactose and galactose permease, GPH translocator family	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956 Gene: LAF_0779: Lactose and galactose permease, GPH translocator family	Lactobacillus helveticus DPC 4571 Gene: lhv_1543: Lactose and galactose permease, GPH translocator family	* Lactobacillus johnsonii NCC 533 Site: position = -112 score = 5.49202 sequence = TATATTTAGTAAATTAT Gene: LJ0857: Lactose and galactose permease, GPH translocator family	Lactobacillus plantarum WCFS1 Gene: lp_3468: Lactose and galactose permease, GPH translocator family	* Lactobacillus reuteri JCM 1112 Site: position = -79 score = 5.15585 sequence = AATATTTACTAAAATTA Gene: LAR_1033: Lactose and galactose permease, GPH translocator family	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1065: Lactose and galactose permease, GPH translocator family	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Lactose and galactose permease, GPH translocator family
lacZ	Lactobacillus acidophilus NCFM Gene: LBA1462: Beta-galactosidase (EC 3.2.1.23)	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	* Lactobacillus fermentum IFO 3956 Site: position = -112 score = 5.49547 sequence = AATATTTACTAATTAAC Gene: LAF_0780: Beta-galactosidase (EC 3.2.1.23)	Lactobacillus helveticus DPC 4571 Gene: lhv_1542: Beta-galactosidase (EC 3.2.1.23)	Lactobacillus johnsonii NCC 533 Gene: LJ0858: Beta-galactosidase (EC 3.2.1.23)	* Lactobacillus plantarum WCFS1 Site: position = -108 score = 5.61286 sequence = GATATTTAGTAATTATT Gene: lp_3469: Beta-galactosidase (EC 3.2.1.23)	Lactobacillus reuteri JCM 1112 Gene: LAR_1032: Beta-galactosidase (EC 3.2.1.23)	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -110 score = 5.35277 sequence = ATCATTTACTAATTTTT Gene: LEUM_1064: Beta-galactosidase (EC 3.2.1.23)	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Beta-galactosidase (EC 3.2.1.23)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog LacR - Lactobacillaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --