Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulog TPP - Pasteurellales

Properties
Regulator type: RNA regulatory element
Name: TPP
RFAM: RF00059
Regulation mode:
Biological process: Thiamine biosynthesis
Effector: Thiamine pyrophosphate
Phylum: Proteobacteria
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Haemophilus influenzae Rd KW20 11 3
Aggregatibacter aphrophilus NJ8700 6 3
Pasteurella multocida subsp. multocida str. Pm70 7 2
Mannheimia succiniciproducens MBEL55E 5 3
Actinobacillus succinogenes 130Z 7 3
Haemophilus somnus 2336 3 1
Actinobacillus pleuropneumoniae serovar 7 str. AP76 15 2
Haemophilus ducreyi 35000HP 1 1
Haemophilus parasuis SH0165 4 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
thiZ
*
Haemophilus influenzae Rd KW20

Site:
position = -161
score = 55.76
sequence = GTTTTTAGTCGGGGT...

Gene: HI0354: Hydroxymethylpyrimidine ABC transporter, ATPase component
 
Aggregatibacter aphrophilus NJ8700
*
Pasteurella multocida subsp. multocida str. Pm70

Site:
position = -185
score = 62.97
sequence = TGCACTTTAGTCGGG...

Gene: PM1266: Hydroxymethylpyrimidine ABC transporter, ATPase component
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Site:
position = -401
score = 69.36
sequence = ATTTTTAGTCGGGGT...

Gene: APP7_0569: Hydroxymethylpyrimidine ABC transporter, ATPase component
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
Hydroxymethylpyrimidine ABC transporter, ATPase component
thiX
 
Haemophilus influenzae Rd KW20

Gene: HI0355: Hydroxymethylpyrimidine ABC transporter, transmembrane component
 
Aggregatibacter aphrophilus NJ8700
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1265: Hydroxymethylpyrimidine ABC transporter, transmembrane component
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_0570: Hydroxymethylpyrimidine ABC transporter, transmembrane component
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
Hydroxymethylpyrimidine ABC transporter, transmembrane component
thiF
 
Haemophilus influenzae Rd KW20
 
Aggregatibacter aphrophilus NJ8700
 
Pasteurella multocida subsp. multocida str. Pm70
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336
 2
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_0571: predicted dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis

Gene: APP7_0572: predicted dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
predicted dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis
thiS
 
Haemophilus influenzae Rd KW20
 
Aggregatibacter aphrophilus NJ8700
 
Pasteurella multocida subsp. multocida str. Pm70
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_0573: thiamine biosynthesis protein ThiS
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
thiamine biosynthesis protein ThiS
thiG
 
Haemophilus influenzae Rd KW20
 
Aggregatibacter aphrophilus NJ8700
 
Pasteurella multocida subsp. multocida str. Pm70
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336
 2
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_0575: Thiazole biosynthesis protein thiG

Gene: APP7_0574: Thiazole biosynthesis protein thiG
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
Thiazole biosynthesis protein thiG
thiH
 
Haemophilus influenzae Rd KW20
 
Aggregatibacter aphrophilus NJ8700
 
Pasteurella multocida subsp. multocida str. Pm70
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_0576: thiazole biosynthesis protein ThiH
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
thiazole biosynthesis protein ThiH
tenA
 
Haemophilus influenzae Rd KW20

Gene: HI0358: Thiaminase II (EC 3.5.99.2)
 
Aggregatibacter aphrophilus NJ8700
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1264: Thiaminase II (EC 3.5.99.2)
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_0577: Thiaminase II (EC 3.5.99.2)
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
Thiaminase II (EC 3.5.99.2)
thiY
 
Haemophilus influenzae Rd KW20

Gene: HI0357: Hydroxymethylpyrimidine ABC transporter, substrate-binding component
 
Aggregatibacter aphrophilus NJ8700
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1263: Hydroxymethylpyrimidine ABC transporter, substrate-binding component
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336
 2
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_0578: Hydroxymethylpyrimidine ABC transporter, substrate-binding component

Gene: APP7_0579: Hydroxymethylpyrimidine ABC transporter, substrate-binding component
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
Hydroxymethylpyrimidine ABC transporter, substrate-binding component
thiD
 
Haemophilus influenzae Rd KW20

Gene: HI0416: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
*
Aggregatibacter aphrophilus NJ8700

Site:
position = -210
score = 58.49
sequence = GTTATTAGTCGGGGT...

Gene: NT05HA_0532: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1261: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
*
Mannheimia succiniciproducens MBEL55E

Site:
position = -234
score = 64.9
sequence = TCCTCATTAGTCGGG...

Gene: MS0677: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
 
Actinobacillus succinogenes 130Z

Gene: Asuc_1507: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
 
Haemophilus somnus 2336
 2
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_0580: Phosphomethylpyrimidine kinase (EC 2.7.4.7)

Gene: APP7_0581: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165

Gene: HAPS_1840: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
Phosphomethylpyrimidine kinase (EC 2.7.4.7)
thiE
 
Haemophilus influenzae Rd KW20

Gene: HI0417: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
*
Aggregatibacter aphrophilus NJ8700

Site:
position = -167
score = 57.15
sequence = TTCGCTTGTCGGAGT...

Gene: NT05HA_1780: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1260: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
Mannheimia succiniciproducens MBEL55E

Gene: MS0676: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
Actinobacillus succinogenes 130Z

Gene: Asuc_1508: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
Haemophilus somnus 2336
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_0582: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165

Gene: HAPS_1839: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
thiB
*
Haemophilus influenzae Rd KW20

Site:
position = -139
score = 57.87
sequence = AAGCCTAGTCGGGGT...

Gene: HI1019: Thiamin ABC transporter, substrate-binding component
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_0533: Thiamin ABC transporter, substrate-binding component
*
Pasteurella multocida subsp. multocida str. Pm70

Site:
position = -129
score = 62.12
sequence = ACTCTTAGTCGGGGT...

Gene: PM0376: Thiamin ABC transporter, substrate-binding component
*
Mannheimia succiniciproducens MBEL55E

Site:
position = -136
score = 60.91
sequence = TCTGTTCTCAACGGG...

Gene: MS1526: Thiamin ABC transporter, substrate-binding component
*
Actinobacillus succinogenes 130Z

Site:
position = -210
score = 43.16
sequence = GGTTCTCATCGGGGT...

Gene: Asuc_1129: Thiamin ABC transporter, substrate-binding component
*
Haemophilus somnus 2336

Site:
position = -156
score = 64.76
sequence = TCCGACTTAGTCGGG...

Gene: HSM_1488: Thiamin ABC transporter, substrate-binding component
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Site:
position = -164
score = 62.15
sequence = CGTTCTCATTGGGGG...

Gene: APP7_0176: Thiamin ABC transporter, substrate-binding component
*
Haemophilus ducreyi 35000HP

Site:
position = -154
score = 62.57
sequence = TGTTCTCATTGGGGT...

Gene: HD0601: Thiamin ABC transporter, substrate-binding component
*
Haemophilus parasuis SH0165

Site:
position = -146
score = 63.36
sequence = TGTTCTCATCGGGGT...

Gene: HAPS_1254: Thiamin ABC transporter, substrate-binding component
Thiamin ABC transporter, substrate-binding component
thiP
 
Haemophilus influenzae Rd KW20

Gene: HI1020: Thiamin ABC transporter, transmembrane component
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_0534: Thiamin ABC transporter, transmembrane component
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM0377: Thiamin ABC transporter, transmembrane component
 
Mannheimia succiniciproducens MBEL55E

Gene: MS1525: Thiamin ABC transporter, transmembrane component
 
Actinobacillus succinogenes 130Z

Gene: Asuc_1130: Thiamin ABC transporter, transmembrane component
 
Haemophilus somnus 2336

Gene: HSM_1487: Thiamin ABC transporter, transmembrane component
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_1372: Thiamin ABC transporter, transmembrane component
 
Haemophilus ducreyi 35000HP

Gene: HD0230: Thiamin ABC transporter, transmembrane component
 
Haemophilus parasuis SH0165

Gene: HAPS_1087: Thiamin ABC transporter, transmembrane component
Thiamin ABC transporter, transmembrane component
thiQ
 
Haemophilus influenzae Rd KW20

Gene: HI1021: Thiamin ABC transporter, ATPase component
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_0535: Thiamin ABC transporter, ATPase component
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM0378: Thiamin ABC transporter, ATPase component
 
Mannheimia succiniciproducens MBEL55E

Gene: MS1524: Thiamin ABC transporter, ATPase component
 
Actinobacillus succinogenes 130Z

Gene: Asuc_1131: Thiamin ABC transporter, ATPase component
 
Haemophilus somnus 2336

Gene: HSM_1486: Thiamin ABC transporter, ATPase component
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_1371: Thiamin ABC transporter, ATPase component
 
Haemophilus ducreyi 35000HP

Gene: HD0231: Thiamin ABC transporter, ATPase component
 
Haemophilus parasuis SH0165

Gene: HAPS_1361: Thiamin ABC transporter, ATPase component
Thiamin ABC transporter, ATPase component
thiM
*
Haemophilus influenzae Rd KW20

Site:
position = -211
score = 54.95
sequence = ACTTTTAGTCGGGGT...

Gene: HI0415: Hydroxyethylthiazole kinase (EC 2.7.1.50)
 
Aggregatibacter aphrophilus NJ8700
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1262: Hydroxyethylthiazole kinase (EC 2.7.1.50)
 
Mannheimia succiniciproducens MBEL55E
*
Actinobacillus succinogenes 130Z

Site:
position = -201
score = 66.11
sequence = CCCATTAGTCGGGGT...

Gene: Asuc_1506: Hydroxyethylthiazole kinase (EC 2.7.1.50)
 
Haemophilus somnus 2336
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76
 
Haemophilus ducreyi 35000HP
*
Haemophilus parasuis SH0165

Site:
position = -262
score = 69.61
sequence = GACATTTAAGTCGGG...

Gene: HAPS_1841: Hydroxyethylthiazole kinase (EC 2.7.1.50)
Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiU
 2
Haemophilus influenzae Rd KW20

Gene: HI0281: Predicted thiazole transporter ThiU

Gene: HI0418: Predicted thiazole transporter ThiU
 
Aggregatibacter aphrophilus NJ8700
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1259: Predicted thiazole transporter ThiU
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165

Gene: HAPS_1072: Predicted thiazole transporter ThiU
Predicted thiazole transporter ThiU
 
CRON 2.
afuA
 
Haemophilus influenzae Rd KW20
*
Aggregatibacter aphrophilus NJ8700

Site:
position = -188
score = 56.48
sequence = CCCGTTAGTCGGGGT...

Gene: NT05HA_1226: ABC transporter substrate-binding protein
 
Pasteurella multocida subsp. multocida str. Pm70
*
Mannheimia succiniciproducens MBEL55E

Site:
position = -272
score = 59.51
sequence = GCCGTTAGTCGGGGT...

Gene: MS1370: ABC transporter substrate-binding protein
*
Actinobacillus succinogenes 130Z

Site:
position = -150
score = 60.11
sequence = TTCCCGTTAGTCGGG...

Gene: Asuc_1267: ABC transporter substrate-binding protein
 
Haemophilus somnus 2336
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
ABC transporter substrate-binding protein
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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