Regulog TPP - Mycobacteriaceae
| Regulator type: | RNA regulatory element |
| Name: | TPP |
| RFAM: | RF00059 |
| Regulation mode: | |
| Biological process: | Thiamine biosynthesis |
| Effector: | Thiamine pyrophosphate |
| Phylum: | Actinobacteria |
Member of regulog collections
- By taxonomy - Mycobacteriaceae
- By RNA motif - TPP
- By effector - Thiamine pyrophosphate
- By pathway - Thiamine biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Mycobacterium tuberculosis H37Rv | 5 | 2 |
| Mycobacterium leprae TN | 5 | 2 |
| Mycobacterium marinum M | 5 | 2 |
| Mycobacterium avium 104 | 5 | 2 |
| Mycobacterium sp. JLS | 7 | 3 |
| Mycobacterium vanbaalenii PYR-1 | 5 | 2 |
| Mycobacterium flavescens PYR-GCK | 8 | 4 |
| Mycobacterium smegmatis str. MC2 155 | 8 | 3 |
| Mycobacterium abscessus ATCC 19977 | 5 | 2 |
| Genes | Function | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||||
| ykoE |
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*
Mycobacterium sp. JLS Site: position = -102 score = 53.32 sequence = CGATAACCCACGCGG... Gene: Mjls_5653: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
|
*
Mycobacterium flavescens PYR-GCK Site: position = -101 score = 47.57 sequence = TGGACGCACACGGGA... Gene: Mflv_0970: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Mycobacterium smegmatis str. MC2 155 Site: position = -105 score = 58.69 sequence = GAACAACCCACGCGG... Gene: MSMEG_6726: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| ykoD |
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Gene: Mjls_5652: ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: Mflv_0971: ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: MSMEG_6725: ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| ykoC |
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Gene: Mjls_5651: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: Mflv_0972: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: MSMEG_6724: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
|
Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| CRON 2. | ||||||||||
| thiC |
*
Mycobacterium tuberculosis H37Rv Site: position = -102 score = 54.53 sequence = GGGGTACCCACGCGG... Gene: Rv0423c: Thiamin biosynthesis protein ThiC |
*
Mycobacterium leprae TN Site: position = -101 score = 55.4 sequence = AAAAACCACGCGGGA... Gene: ML0294: Thiamin biosynthesis protein ThiC |
*
Mycobacterium marinum M Site: position = -113 score = 50.11 sequence = AATTAACGCACGCGG... Gene: MMAR_0735: Thiamin biosynthesis protein ThiC |
*
Mycobacterium avium 104 Site: position = -102 score = 48.22 sequence = TCCATCAGACGCGGG... Gene: MAV_4731: Thiamin biosynthesis protein ThiC |
|
*
Mycobacterium vanbaalenii PYR-1 Site: position = -98 score = 47.42 sequence = CACTAACGCGGGAGC... Gene: Mvan_0725: Thiamin biosynthesis protein ThiC |
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Mycobacterium flavescens PYR-GCK Site: position = -105 score = 49.55 sequence = GTCGACCACTCGCGG... Gene: Mflv_0754: Thiamin biosynthesis protein ThiC |
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Mycobacterium smegmatis str. MC2 155 Site: position = -163 score = 51.8 sequence = CAGAGAAAACCGCGG... Gene: MSMEG_0826: Thiamin biosynthesis protein ThiC |
*
Mycobacterium abscessus ATCC 19977 Site: position = -103 score = 55.71 sequence = CCCACAAACACGGGA... Gene: MAB_4196: Thiamin biosynthesis protein ThiC |
Thiamin biosynthesis protein ThiC |
| thiD |
Gene: Rv0422c: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: ML0295: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: MMAR_0734: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: MAV_4732: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
*
Mycobacterium sp. JLS Site: position = -100 score = 54.1 sequence = CCACCGACCACGCGG... Gene: Mjls_0554: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: Mvan_0724: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
*
Mycobacterium flavescens PYR-GCK Site: position = -96 score = 41.21 sequence = AACACGCGGGAGCGC... Gene: Mflv_0181: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: MSMEG_0825: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: MAB_4197: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
| CRON 3. | ||||||||||
| thiO |
*
Mycobacterium tuberculosis H37Rv Site: position = -100 score = 45.59 sequence = CCTGTAGACACGGGA... Gene: Rv0415: Glycine oxidase ThiO (EC 1.4.3.19) |
*
Mycobacterium leprae TN Site: position = -130 score = 41.1 sequence = AACTTCAGTACACGG... Gene: ML0299: Glycine oxidase ThiO (EC 1.4.3.19) |
*
Mycobacterium marinum M Site: position = -120 score = 40.88 sequence = CTGAAGAACACGGGA... Gene: MMAR_0718: Glycine oxidase ThiO (EC 1.4.3.19) |
*
Mycobacterium avium 104 Site: position = -102 score = 43.3 sequence = TCGTTTTAGACACGG... Gene: MAV_4746: Glycine oxidase ThiO (EC 1.4.3.19) |
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Mycobacterium sp. JLS Site: position = -105 score = 43.74 sequence = TGATGGCCGACACGG... Gene: Mjls_0535: Glycine oxidase ThiO (EC 1.4.3.19) |
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Mycobacterium vanbaalenii PYR-1 Site: position = -91 score = 40.41 sequence = ACGGGAGTCCCGGGT... Gene: Mvan_0708: Glycine oxidase ThiO (EC 1.4.3.19) |
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Mycobacterium flavescens PYR-GCK Site: position = -92 score = 41.2 sequence = CACACGGGAGTCCCG... Gene: Mflv_0197: Glycine oxidase ThiO (EC 1.4.3.19) |
*
Mycobacterium smegmatis str. MC2 155 Site: position = -102 score = 46.81 sequence = ACGGGCAACACGGGA... Gene: MSMEG_0791: Glycine oxidase ThiO (EC 1.4.3.19) |
*
Mycobacterium abscessus ATCC 19977 Site: position = -113 score = 55.11 sequence = GTGTAAGTAACGCGG... Gene: MAB_4218c: Glycine oxidase ThiO (EC 1.4.3.19) |
Glycine oxidase ThiO (EC 1.4.3.19) |
| thiS |
Gene: Rv0416: Sulfur carrier protein ThiS |
Gene: ML0298: Sulfur carrier protein ThiS |
Gene: MMAR_0719: Sulfur carrier protein ThiS |
Gene: MAV_4745: Sulfur carrier protein ThiS |
Gene: Mjls_0536: Sulfur carrier protein ThiS |
Gene: Mvan_0709: Sulfur carrier protein ThiS |
Gene: Mflv_0196: Sulfur carrier protein ThiS |
Gene: MSMEG_0792: Sulfur carrier protein ThiS |
Gene: MAB_4217c: Sulfur carrier protein ThiS |
Sulfur carrier protein ThiS |
| thiG |
Gene: Rv0417: Thiazole biosynthesis protein ThiG |
Gene: ML0297: Thiazole biosynthesis protein ThiG |
Gene: MMAR_0720: Thiazole biosynthesis protein ThiG |
Gene: MAV_4744: Thiazole biosynthesis protein ThiG |
Gene: Mjls_0537: Thiazole biosynthesis protein ThiG |
Gene: Mvan_0710: Thiazole biosynthesis protein ThiG |
Gene: Mflv_0195: Thiazole biosynthesis protein ThiG |
Gene: MSMEG_0793: Thiazole biosynthesis protein ThiG |
Gene: MAB_4216c: Thiazole biosynthesis protein ThiG |
Thiazole biosynthesis protein ThiG |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |