Regulog T-box(Val) - Clostridiaceae

Properties
Regulator type:	RNA regulatory element
Name:	T-box
RFAM:	RF00230
Regulation mode:
Biological process:	Amino acid metabolism
Effector:	Val-tRNA
Phylum:	Firmicutes

Member of regulog collections

By taxonomy - Clostridiaceae
By RNA motif - T-box
By effector - Val-tRNA
By pathway - Amino acid metabolism

Statistics of regulated genes
Genome	Genes	Operons
Clostridium kluyveri DSM 555	1	1
Clostridium sp. SS2/1
Clostridium cellulolyticum H10	2	1
Clostridium phytofermentans ISDg	3	2
Clostridium tetani E88	1	1
Clostridium acetobutylicum ATCC 824	2	2
Clostridium botulinum A str. ATCC 3502	2	1
Clostridium novyi NT	1	1
Clostridium perfringens ATCC 13124	1	1
Clostridium difficile 630	1	1
Clostridium beijerincki NCIMB 8052	3	2
Clostridium sp. OhILAs	1	1
Clostridium sp. L2-50	3	2
Clostridium scindens ATCC 35704	4	2
Clostridium nexile DSM 1787	1	1
Clostridium leptum DSM 753
Clostridium hiranonis DSM 13275	1	1
Clostridium butyricum 5521	1	1
Clostridium bolteae ATCC BAA-613
Clostridium bartlettii DSM 16795	1	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																					Function

CRON 1.
CD2125	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	* Clostridium botulinum A str. ATCC 3502 Site: position = -298 score = 109.69 sequence = AAATAAAGCTTTGAA... Gene: CBO3165: Acetyltransferase (GNAT) family protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Acetyltransferase, GNAT family
valS	* Clostridium kluyveri DSM 555 Site: position = -268 score = 109.12 sequence = TGTAATCACTGTGAA... Gene: CKL_3219: Valyl-tRNA synthetase (EC 6.1.1.9)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1199: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium phytofermentans ISDg Site: position = -455 score = 90.13 sequence = TAAATGTAGTGATGG... Gene: null: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium tetani E88 Site: position = -307 score = 103.96 sequence = AATAAAAGCTGTGAA... Gene: CTC02302: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium acetobutylicum ATCC 824 Site: position = -268 score = 120.28 sequence = AATATAAACGCTGAA... Gene: CAC2399: Valyl-tRNA synthetase (EC 6.1.1.9)	Clostridium botulinum A str. ATCC 3502 Gene: CBO3164: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium novyi NT Site: position = -282 score = 107.6 sequence = TAAAAACAGAGAAAA... Gene: NT01CX_1727: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium perfringens ATCC 13124 Site: position = -446 score = 117.86 sequence = GATACAAACAGTGAT... Gene: CPF_2175: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium difficile 630 Site: position = -339 score = 97.55 sequence = ATTAAAGACTGAGAA... Gene: CD3256: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium beijerincki NCIMB 8052 Site: position = -495 score = 80.34 sequence = CTAAATCATAGATTT... Gene: Cbei_1782: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium sp. OhILAs Site: position = -283 score = 128.02 sequence = GATATCAACAATGAT... Gene: Clos_2038: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium sp. L2-50 Site: position = -178 score = 106.59 sequence = CATAAATGCAAGGAA... Gene: CLOL250_01610: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium scindens ATCC 35704 Site: position = -335 score = 97.97 sequence = CGTAAAGGCATTGAA... Gene: CLOSCI_02273: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium nexile DSM 1787 Site: position = -195 score = 94.78 sequence = GCAAAAGGTAATGAG... Gene: CLONEX_03903: Valyl-tRNA synthetase (EC 6.1.1.9)	Clostridium leptum DSM 753	* Clostridium hiranonis DSM 13275 Site: position = -377 score = 123.63 sequence = TACAGACGTTGAAGA... Gene: CLOHIR_00746: Valyl-tRNA synthetase (EC 6.1.1.9)	* Clostridium butyricum 5521 Site: position = -443 score = 107.35 sequence = TAAAAGCAATGATAA... Gene: CBY_0347: Valyl-tRNA synthetase (EC 6.1.1.9)	Clostridium bolteae ATCC BAA-613	* Clostridium bartlettii DSM 16795 Site: position = -383 score = 108.17 sequence = AAAAGACTGAGAAAA... Gene: CLOBAR_00333: Valyl-tRNA synthetase (EC 6.1.1.9)	Valyl-tRNA synthetase (EC 6.1.1.9)
Ccel_1198	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	* Clostridium cellulolyticum H10 Site: position = -283 score = 102.13 sequence = TAAAGGCTGTGAATA... Gene: Ccel_1198: hypothetical protein	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein

CRON 2.
ilvD	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	* Clostridium phytofermentans ISDg Site: position = -348 score = 50.36 sequence = ACTTATAGCCATATG... Gene: Cphy_3348: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Dihydroxy-acid dehydratase (EC 4.2.1.9)
ilvB	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: Cphy_3347: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	* Clostridium beijerincki NCIMB 8052 Site: position = -402 score = 106.83 sequence = TAAAAACTGTGAAGA... Gene: Cbei_2646: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Acetolactate synthase large subunit (EC 2.2.1.6)
ilvH1	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2647: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Acetolactate synthase small subunit (EC 2.2.1.6)

CRON 3.
ilvB1	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_00852: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	* Clostridium sp. L2-50 Site: position = -352 score = 111.61 sequence = GTCAAATGCAATGAC... Gene: CLOL250_00238: Acetolactate synthase large subunit (EC 2.2.1.6)	* Clostridium scindens ATCC 35704 Site: position = -326 score = 103.43 sequence = GAAATGCTATGACAA... Gene: CLOSCI_01159: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium nexile DSM 1787 Gene: CLONEX_03220: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00918: Acetolactate synthase large subunit (EC 2.2.1.6)	Acetolactate synthase large subunit (EC 2.2.1.6)
ilvH2	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_00851: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_00237: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01160: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium nexile DSM 1787 Gene: CLONEX_03219: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00919: Acetolactate synthase small subunit (EC 2.2.1.6)	Acetolactate synthase small subunit (EC 2.2.1.6)
ilvE1	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_00092: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_1772: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1043: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Clostridium sp. OhILAs Gene: Clos_0407: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Clostridium sp. L2-50 Gene: CLOL250_00400: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01161: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Clostridium nexile DSM 1787 Gene: CLONEX_03218: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0273: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_04945: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Clostridium bartlettii DSM 16795	Branched-chain amino acid aminotransferase (EC 2.6.1.42)

CRON 4.
ilvC	2 Clostridium kluyveri DSM 555 Gene: CKL_1080: Ketol-acid reductoisomerase (EC 1.1.1.86) Gene: CKL_1089: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium sp. SS2/1 Gene: CLOSS21_01058: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium cellulolyticum H10 Gene: Ccel_3435: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium phytofermentans ISDg Gene: null: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium tetani E88	* Clostridium acetobutylicum ATCC 824 Site: position = -393 score = 107.79 sequence = CAAAGACAATGATGA... Gene: CAC0091: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT Gene: NT01CX_2028: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD1565: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_00225: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium scindens ATCC 35704 Gene: CLOSCI_00393: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium nexile DSM 1787 Gene: CLONEX_01516: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium leptum DSM 753 Gene: CLOLEP_00058: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01818: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium butyricum 5521 Gene: CBY_2921: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05328: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01659: Ketol-acid reductoisomerase (EC 1.1.1.86)	Ketol-acid reductoisomerase (EC 1.1.1.86)