Statistics of regulated genes

Genome	Genes	Operons
Clostridium kluyveri DSM 555	1	1
Clostridium sp. SS2/1
Clostridium cellulolyticum H10	1	1
Clostridium phytofermentans ISDg	1	1
Clostridium tetani E88	1	1
Clostridium acetobutylicum ATCC 824	1	1
Clostridium botulinum A str. ATCC 3502	1	1
Clostridium novyi NT	1	1
Clostridium perfringens ATCC 13124	2	1
Clostridium difficile 630	1	1
Clostridium beijerincki NCIMB 8052	1	1
Clostridium sp. OhILAs	5	4
Clostridium sp. L2-50
Clostridium scindens ATCC 35704	1	1
Clostridium nexile DSM 1787	1	1
Clostridium leptum DSM 753
Clostridium hiranonis DSM 13275	1	1
Clostridium butyricum 5521	1	1
Clostridium bolteae ATCC BAA-613
Clostridium bartlettii DSM 16795	1	1

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes																					Function
CRON 1.
metS	* Clostridium kluyveri DSM 555 Site: position = -316 score = 91.09 sequence = GTTAAATACTATGAA... Gene: CKL_3766: Methionyl-tRNA synthetase (EC 6.1.1.10)	Clostridium sp. SS2/1 Gene: CLOSS21_02673: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium cellulolyticum H10 Site: position = -306 score = 74.37 sequence = TACAGGCTGTGAAGA... Gene: Ccel_1098: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium phytofermentans ISDg Site: position = -416 score = 87.05 sequence = AAAATGCTGAGAAAA... Gene: null: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium tetani E88 Site: position = -318 score = 86.42 sequence = AAAATGCAATGAAAG... Gene: CTC00243: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium acetobutylicum ATCC 824 Site: position = -308 score = 92.38 sequence = TTCAAAAGCATTGAT... Gene: CAC2991: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium botulinum A str. ATCC 3502 Site: position = -302 score = 93.81 sequence = TAAATGCTATGAAGG... Gene: CBO0075: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium novyi NT Site: position = -330 score = 66.27 sequence = AGAAAATGCAGTGAA... Gene: NT01CX_0697: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium perfringens ATCC 13124 Site: position = -332 score = 85.66 sequence = AGAAAATGCAATGAA... Gene: CPF_2847: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium difficile 630 Site: position = -331 score = 104.83 sequence = ATTACAAGCTATGAA... Gene: CD3540: Methionyl-tRNA synthetase (EC 6.1.1.10)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0055: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium sp. OhILAs Site: position = -306 score = 111.04 sequence = TCTAAAAGCAGTGAT... Gene: Clos_2662: Methionyl-tRNA synthetase (EC 6.1.1.10)	Clostridium sp. L2-50 Gene: CLOL250_01279: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium scindens ATCC 35704 Site: position = -366 score = 50.67 sequence = CAAACGCAGTGACGG... Gene: CLOSCI_03024: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium nexile DSM 1787 Site: position = -267 score = 75.53 sequence = AGGAAACGCAATGAT... Gene: CLONEX_03592: Methionyl-tRNA synthetase (EC 6.1.1.10)	Clostridium leptum DSM 753 Gene: CLOLEP_02543: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium hiranonis DSM 13275 Site: position = -288 score = 111.11 sequence = TAAAAGCGATGAAGA... Gene: CLOHIR_01636: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium butyricum 5521 Site: position = -440 score = 95.98 sequence = TTTAAATGCATTGAA... Gene: CBY_2255: Methionyl-tRNA synthetase (EC 6.1.1.10)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_04510: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium bartlettii DSM 16795 Site: position = -267 score = 132.73 sequence = TAAAAGCAATGAAGA... Gene: CLOBAR_02505: Methionyl-tRNA synthetase (EC 6.1.1.10)	Methionyl-tRNA synthetase (EC 6.1.1.10)
metS2	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_2846: Methionyl-tRNA synthetase, clostridial paralog	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	* Clostridium sp. OhILAs Site: position = -303 score = 117.9 sequence = TAAATGCGAAGAAAA... Gene: Clos_1003: Methionyl-tRNA synthetase, clostridial paralog	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_2254: Methionyl-tRNA synthetase, clostridial paralog	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Methionyl-tRNA synthetase, clostridial paralog
CRON 2.
metS3	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_0205: Methionyl-tRNA synthetase (EC 6.1.1.10)	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	* Clostridium beijerincki NCIMB 8052 Site: position = -285 score = 32.04 sequence = ATTATAAGTGATGCT... Gene: Cbei_3185: Methionyl-tRNA synthetase (EC 6.1.1.10)	* Clostridium sp. OhILAs Site: position = -360 score = 99.55 sequence = TAAAGGCTGTGAAGA... Gene: Clos_1001: Methionyl-tRNA synthetase (EC 6.1.1.10)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Methionyl-tRNA synthetase (EC 6.1.1.10)
CRON 3.
metN	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Methionine ABC transporter ATP-binding protein	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	* Clostridium sp. OhILAs Site: position = -335 score = 95.85 sequence = CAAAGACGTTGAAGA... Gene: Clos_0125: Methionine ABC transporter ATP-binding protein	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Methionine ABC transporter ATP-binding protein
metP	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Methionine ABC transporter permease protein	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0126: Methionine ABC transporter permease protein	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Methionine ABC transporter permease protein

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