Regulog T-box(Ile) - Clostridiaceae

Properties
Regulator type:	RNA regulatory element
Name:	T-box
RFAM:	RF00230
Regulation mode:
Biological process:	Amino acid metabolism
Effector:	Ile-tRNA
Phylum:	Firmicutes

Member of regulog collections

By taxonomy - Clostridiaceae
By RNA motif - T-box
By effector - Ile-tRNA
By pathway - Amino acid metabolism

Statistics of regulated genes
Genome	Genes	Operons
Clostridium kluyveri DSM 555	2	2
Clostridium sp. SS2/1	1	1
Clostridium cellulolyticum H10	1	1
Clostridium phytofermentans ISDg	1	1
Clostridium tetani E88	2	2
Clostridium acetobutylicum ATCC 824	2	2
Clostridium botulinum A str. ATCC 3502	1	1
Clostridium novyi NT	5	3
Clostridium perfringens ATCC 13124	2	2
Clostridium difficile 630	1	1
Clostridium beijerincki NCIMB 8052	8	2
Clostridium sp. OhILAs
Clostridium sp. L2-50	1	1
Clostridium scindens ATCC 35704	1	1
Clostridium nexile DSM 1787	1	1
Clostridium leptum DSM 753	3	1
Clostridium hiranonis DSM 13275	1	1
Clostridium butyricum 5521	8	2
Clostridium bolteae ATCC BAA-613	1	1
Clostridium bartlettii DSM 16795	4	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																					Function

CRON 1.
ilvH	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_01059: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3176: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	* Clostridium beijerincki NCIMB 8052 Site: position = -274 score = 54.67 sequence = AAAATGCTGAGATGG... Gene: Cbei_0212: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_00226: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium scindens ATCC 35704 Gene: CLOSCI_00392: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium nexile DSM 1787 Gene: CLONEX_01515: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium leptum DSM 753 Gene: CLOLEP_00059: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01817: Acetolactate synthase small subunit (EC 2.2.1.6)	* Clostridium butyricum 5521 Site: position = -275 score = 48.85 sequence = GAAATGCTAAGAAGG... Gene: CBY_2932: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05327: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium bartlettii DSM 16795	Acetolactate synthase small subunit (EC 2.2.1.6)
leuA	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1624: 2-isopropylmalate synthase (EC 2.3.3.13)	Clostridium phytofermentans ISDg Gene: null: 2-isopropylmalate synthase (EC 2.3.3.13)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3174: 2-isopropylmalate synthase (EC 2.3.3.13)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0213: 2-isopropylmalate synthase (EC 2.3.3.13)	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753 Gene: CLOLEP_00228: 2-isopropylmalate synthase (EC 2.3.3.13)	Clostridium hiranonis DSM 13275	2 Clostridium butyricum 5521 Gene: CBY_2933: 2-isopropylmalate synthase (EC 2.3.3.13) Gene: CBY_2668: 2-isopropylmalate synthase (EC 2.3.3.13)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05023: 2-isopropylmalate synthase (EC 2.3.3.13)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01139: 2-isopropylmalate synthase (EC 2.3.3.13)	2-isopropylmalate synthase (EC 2.3.3.13)
leuC	Clostridium kluyveri DSM 555	2 Clostridium sp. SS2/1 Gene: CLOSS21_00397: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) Gene: CLOSS21_00399: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	2 Clostridium cellulolyticum H10 Gene: Ccel_1622: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) Gene: Ccel_0126: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Clostridium phytofermentans ISDg Gene: null: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3173: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0214: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02807: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Clostridium scindens ATCC 35704 Gene: CLOSCI_03560: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Clostridium nexile DSM 1787 Gene: CLONEX_03207: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Clostridium leptum DSM 753 Gene: CLOLEP_00224: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_2934: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05331: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01138: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)	3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
leuD	Clostridium kluyveri DSM 555	2 Clostridium sp. SS2/1 Gene: CLOSS21_00396: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) Gene: CLOSS21_00398: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	2 Clostridium cellulolyticum H10 Gene: Ccel_1621: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) Gene: Ccel_0127: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Clostridium phytofermentans ISDg Gene: null: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3172: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0215: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02806: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Clostridium scindens ATCC 35704 Gene: CLOSCI_03561: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Clostridium nexile DSM 1787 Gene: CLONEX_03206: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Clostridium leptum DSM 753 Gene: CLOLEP_00223: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_2935: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05332: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01137: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)	3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuB	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_01908: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium cellulolyticum H10 Gene: Ccel_0128: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium phytofermentans ISDg Gene: null: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3171: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT Gene: NT01CX_0635: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0216: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02805: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium scindens ATCC 35704 Gene: CLOSCI_00709: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium nexile DSM 1787 Gene: CLONEX_01402: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium leptum DSM 753 Gene: CLOLEP_02914: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_2936: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02301: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01136: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)	3-isopropylmalate dehydrogenase (EC 1.1.1.85)
ilvB	Clostridium kluyveri DSM 555 Gene: CKL_1081: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium sp. SS2/1 Gene: CLOSS21_01906: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium cellulolyticum H10 Gene: Ccel_0303: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3169: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT Gene: NT01CX_2029: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD1566: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0217: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02803: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium scindens ATCC 35704 Gene: CLOSCI_00707: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium nexile DSM 1787 Gene: CLONEX_01404: Acetolactate synthase large subunit (EC 2.2.1.6)	2 Clostridium leptum DSM 753* Site: position = -483 score = 125.19 sequence = GACAAATGCGTTGAT... Gene: CLOLEP_00230: Acetolactate synthase large subunit (EC 2.2.1.6) Gene: CLOLEP_00060: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01820: Acetolactate synthase large subunit (EC 2.2.1.6)	2 Clostridium butyricum 5521 Gene: CBY_2938: Acetolactate synthase large subunit (EC 2.2.1.6) Gene: CBY_0762: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02299: Acetolactate synthase large subunit (EC 2.2.1.6)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01660: Acetolactate synthase large subunit (EC 2.2.1.6)	Acetolactate synthase large subunit (EC 2.2.1.6)
ilvC	Clostridium kluyveri DSM 555 Gene: CKL_1080: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium sp. SS2/1 Gene: CLOSS21_01058: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	* Clostridium novyi NT Site: position = -482 score = 101.21 sequence = GAAAAACGAAGACGG... Site: position = -246 score = 104.08 sequence = GAAAAACGAAGACGG... Gene: NT01CX_2028: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD1565: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0218: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_00225: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium scindens ATCC 35704 Gene: CLOSCI_00393: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium nexile DSM 1787 Gene: CLONEX_01516: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium leptum DSM 753 Gene: CLOLEP_00058: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01818: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium butyricum 5521 Gene: CBY_2921: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05328: Ketol-acid reductoisomerase (EC 1.1.1.86)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01659: Ketol-acid reductoisomerase (EC 1.1.1.86)	Ketol-acid reductoisomerase (EC 1.1.1.86)
ilvD	Clostridium kluyveri DSM 555 Gene: CKL_1693: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium sp. SS2/1 Gene: CLOSS21_01907: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium cellulolyticum H10 Gene: Ccel_0302: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3170: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT Gene: NT01CX_2027: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD2014: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1510: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02804: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium scindens ATCC 35704 Gene: CLOSCI_00708: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium nexile DSM 1787 Gene: CLONEX_01403: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium leptum DSM 753 Gene: CLOLEP_01736: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01819: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium butyricum 5521 Gene: CBY_2937: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02300: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00390: Dihydroxy-acid dehydratase (EC 4.2.1.9)	Dihydroxy-acid dehydratase (EC 4.2.1.9)
ilvE	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	2 Clostridium novyi NT Gene: NT01CX_2030: Branched-chain amino acid aminotransferase (EC 2.6.1.42) Gene: NT01CX_0183: Branched-chain amino acid aminotransferase (EC 2.6.1.42)	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Branched-chain amino acid aminotransferase (EC 2.6.1.42)
ilvH1	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753 Gene: CLOLEP_00229: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0761: Acetolactate synthase small subunit (EC 2.2.1.6)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Acetolactate synthase small subunit (EC 2.2.1.6)
CD1564	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	* Clostridium bartlettii DSM 16795 Site: position = -383 score = 106.68 sequence = TAAAAGCTTTGACGG... Gene: CLOBAR_01658: hypothetical protein	hypothetical protein

CRON 2.
ileS	* Clostridium kluyveri DSM 555 Site: position = -372 score = 94.29 sequence = TTTAAAAACTTTGAA... Gene: CKL_3752: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium sp. SS2/1 Site: position = -267 score = 71.07 sequence = TAAAAGCGAAGAAGG... Gene: CLOSS21_00568: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium cellulolyticum H10 Site: position = -320 score = 118.52 sequence = CCTAAATATGATGAT... Gene: Ccel_1855: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium phytofermentans ISDg Site: position = -380 score = 68.63 sequence = TGTAAAGACGTTGAC... Gene: null: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium tetani E88 Site: position = -290 score = 106.34 sequence = TAAATGCTATGAAAA... Gene: CTC00261: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium acetobutylicum ATCC 824 Site: position = -346 score = 84.1 sequence = GAAAATAGTGTAGAA... Gene: CAC3038: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium botulinum A str. ATCC 3502 Site: position = -295 score = 91.08 sequence = TAAAAGCGGTGAACA... Gene: CBO0099: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium novyi NT Site: position = -337 score = 82.97 sequence = ATTAATAACTATGAA... Gene: NT01CX_0646: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium perfringens ATCC 13124 Site: position = -383 score = 76.1 sequence = TTTAAAGACTGTGAA... Gene: CPF_2865: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium difficile 630 Site: position = -326 score = 113.71 sequence = TTTAAAAGCGTTGAT... Gene: CD2618: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium beijerincki NCIMB 8052 Site: position = -341 score = 85.49 sequence = AAAAGACGATGATTA... Gene: Cbei_0046: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	Clostridium sp. OhILAs Gene: Clos_2197: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium sp. L2-50 Site: position = -415 score = 69.75 sequence = GAAAAGCGATGACAG... Gene: CLOL250_01976: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium scindens ATCC 35704 Site: position = -281 score = 55.87 sequence = GAAAGATGTTGACGA... Gene: CLOSCI_02632: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium nexile DSM 1787 Site: position = -170 score = 80.34 sequence = TGAAAAAACGTTGAC... Gene: CLONEX_02311: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	Clostridium leptum DSM 753 Gene: CLOLEP_01959: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium hiranonis DSM 13275 Site: position = -355 score = 111.71 sequence = TAAAGGCTATGATGA... Gene: CLOHIR_01069: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium butyricum 5521 Site: position = -386 score = 78.52 sequence = ATAAAAGACTATGAT... Gene: CBY_2265: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium bolteae ATCC BAA-613 Site: position = -303 score = 64.79 sequence = GAAAAAGGCATAGAT... Gene: CLOBOL_06015: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	* Clostridium bartlettii DSM 16795 Site: position = -431 score = 120.63 sequence = AATAAAAGCTGTGAT... Gene: CLOBAR_02773: Isoleucyl-tRNA synthetase (EC 6.1.1.5)	Isoleucyl-tRNA synthetase (EC 6.1.1.5)

CRON 3.
brnQ	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	* Clostridium tetani E88 Site: position = -391 score = 112.27 sequence = AACAAATTCTGTGAA... Gene: CTC01868: Branched-chain amino acid transport system carrier protein	* Clostridium acetobutylicum ATCC 824 Site: position = -340 score = 104.29 sequence = TATAAATTCTATGAA... Gene: CAC1610: Branched-chain amino acid transport system carrier protein	Clostridium botulinum A str. ATCC 3502	* Clostridium novyi NT Site: position = -386 score = 110.65 sequence = TAAATTCTATGAAGA... Gene: NT01CX_1315: Branched-chain amino acid transport system carrier protein	* Clostridium perfringens ATCC 13124 Site: position = -416 score = 114.55 sequence = TAAATTCTATGAAGA... Gene: CPF_0392: Branched-chain amino acid transport system carrier protein	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	2 Clostridium nexile DSM 1787 Gene: CLONEX_02683: Branched-chain amino acid transport system carrier protein Gene: CLONEX_04179: Branched-chain amino acid transport system carrier protein	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_3935: Branched-chain amino acid transport system carrier protein	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_06938: Branched-chain amino acid transport system carrier protein	Clostridium bartlettii DSM 16795	Branched-chain amino acid transport system carrier protein

CRON 4.
ilvA	* Clostridium kluyveri DSM 555 Site: position = -373 score = 99.09 sequence = ATAAAACTAAGATGG... Gene: CKL_0426: Threonine dehydratase (EC 4.3.1.19)	Clostridium sp. SS2/1 Gene: CLOSS21_00044: Threonine dehydratase (EC 4.3.1.19)	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Threonine dehydratase (EC 4.3.1.19)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO3502: Threonine dehydratase (EC 4.3.1.19)	Clostridium novyi NT Gene: NT01CX_2074: Threonine dehydratase (EC 4.3.1.19)	Clostridium perfringens ATCC 13124 Gene: CPF_1368: Threonine dehydratase (EC 4.3.1.19)	Clostridium difficile 630 Gene: CD2514: Threonine dehydratase (EC 4.3.1.19)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1562: Threonine dehydratase (EC 4.3.1.19)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_00213: Threonine dehydratase (EC 4.3.1.19)	Clostridium scindens ATCC 35704 Gene: CLOSCI_00627: Threonine dehydratase (EC 4.3.1.19)	Clostridium nexile DSM 1787 Gene: CLONEX_01571: Threonine dehydratase (EC 4.3.1.19)	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01990: Threonine dehydratase (EC 4.3.1.19)	Clostridium butyricum 5521 Gene: CBY_0965: Threonine dehydratase (EC 4.3.1.19)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02896: Threonine dehydratase (EC 4.3.1.19)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00898: Threonine dehydratase (EC 4.3.1.19)	Threonine dehydratase (EC 4.3.1.19)