Regulog T-box(Cys) - Clostridiaceae

Properties
Regulator type:	RNA regulatory element
Name:	T-box
RFAM:	RF00230
Regulation mode:
Biological process:	Amino acid metabolism
Effector:	Cys-tRNA
Phylum:	Firmicutes

Member of regulog collections

By taxonomy - Clostridiaceae
By RNA motif - T-box
By effector - Cys-tRNA
By pathway - Amino acid metabolism

Statistics of regulated genes
Genome	Genes	Operons
Clostridium kluyveri DSM 555	5	2
Clostridium sp. SS2/1	2	1
Clostridium cellulolyticum H10
Clostridium phytofermentans ISDg	2	1
Clostridium tetani E88	1	1
Clostridium acetobutylicum ATCC 824	7	3
Clostridium botulinum A str. ATCC 3502	7	3
Clostridium novyi NT	1	1
Clostridium perfringens ATCC 13124	8	4
Clostridium difficile 630
Clostridium beijerincki NCIMB 8052	2	1
Clostridium sp. OhILAs	2	1
Clostridium sp. L2-50
Clostridium scindens ATCC 35704	2	1
Clostridium nexile DSM 1787	2	1
Clostridium leptum DSM 753
Clostridium hiranonis DSM 13275
Clostridium butyricum 5521	2	1
Clostridium bolteae ATCC BAA-613
Clostridium bartlettii DSM 16795

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																					Function

CRON 1.
cysK	* Clostridium kluyveri DSM 555 Site: position = -330 score = 115.07 sequence = CAGAAATACTTTGAA... Gene: CKL_3413: Cysteine synthase (EC 2.5.1.47)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	* Clostridium botulinum A str. ATCC 3502 Site: position = -297 score = 121.73 sequence = TAAAAACGTTGAAAA... Gene: CBO0205: Cysteine synthase (EC 2.5.1.47)	Clostridium novyi NT	* Clostridium perfringens ATCC 13124 Site: position = -281 score = 109.74 sequence = GATAAATGTTGTGAT... Gene: CPF_1529: Cysteine synthase (EC 2.5.1.47)	Clostridium difficile 630 Gene: CD1594: Cysteine synthase (EC 2.5.1.47)	* Clostridium beijerincki NCIMB 8052 Site: position = -267 score = 47.79 sequence = TTAAAAAATGGAGCG... Gene: Cbei_0577: Cysteine synthase (EC 2.5.1.47)	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01723: Cysteine synthase (EC 2.5.1.47)	* Clostridium butyricum 5521 Site: position = -477 score = 117.88 sequence = TAAAAACTATGAAAA... Gene: CBY_4054: Cysteine synthase (EC 2.5.1.47)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02045: Cysteine synthase (EC 2.5.1.47)	Cysteine synthase (EC 2.5.1.47)
cysE	Clostridium kluyveri DSM 555 Gene: CKL_3412: Serine acetyltransferase (EC 2.3.1.30)	* Clostridium sp. SS2/1 Site: position = -225 score = 101.99 sequence = TAAATGCAATGAACA... Gene: CLOSS21_00208: Serine acetyltransferase (EC 2.3.1.30)	Clostridium cellulolyticum H10 Gene: Ccel_3325: Serine acetyltransferase (EC 2.3.1.30)	* Clostridium phytofermentans ISDg Site: position = -370 score = 114.37 sequence = GTGAAAAGCATTGAT... Gene: null: Serine acetyltransferase (EC 2.3.1.30)	* Clostridium tetani E88 Site: position = -282 score = 92.12 sequence = AAAATACATTGAAAG... Gene: CTC00351: Serine acetyltransferase (EC 2.3.1.30)	* Clostridium acetobutylicum ATCC 824 Site: position = -269 score = 88.99 sequence = GAAATGCTTTGATAA... Gene: CAC0687: Serine acetyltransferase (EC 2.3.1.30)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0206: Serine acetyltransferase (EC 2.3.1.30)	* Clostridium novyi NT Site: position = -305 score = 75.35 sequence = GAAATACAGTGAAGA... Gene: NT01CX_1391: Serine acetyltransferase (EC 2.3.1.30)	Clostridium perfringens ATCC 13124 Gene: CPF_1528: Serine acetyltransferase (EC 2.3.1.30)	Clostridium difficile 630 Gene: CD1595: Serine acetyltransferase (EC 2.3.1.30)	2 Clostridium beijerincki NCIMB 8052 Gene: Cbei_0247: Serine acetyltransferase (EC 2.3.1.30) Gene: Cbei_0578: Serine acetyltransferase (EC 2.3.1.30)	* Clostridium sp. OhILAs Site: position = -315 score = 107.52 sequence = AAAAAGCGAAGAACA... Gene: Clos_0468: Serine acetyltransferase (EC 2.3.1.30)	Clostridium sp. L2-50	* Clostridium scindens ATCC 35704 Site: position = -305 score = 101.99 sequence = AAAAGACGCTGAACG... Gene: CLOSCI_01225: Serine acetyltransferase (EC 2.3.1.30)	* Clostridium nexile DSM 1787 Site: position = -311 score = 110.11 sequence = GAGAAAGACTTAGAA... Gene: CLONEX_00247: Serine acetyltransferase (EC 2.3.1.30)	Clostridium leptum DSM 753 Gene: CLOLEP_01986: Serine acetyltransferase (EC 2.3.1.30)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01722: Serine acetyltransferase (EC 2.3.1.30)	Clostridium butyricum 5521 Gene: CBY_4055: Serine acetyltransferase (EC 2.3.1.30)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_04948: Serine acetyltransferase (EC 2.3.1.30)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02044: Serine acetyltransferase (EC 2.3.1.30)	Serine acetyltransferase (EC 2.3.1.30)
cysS	Clostridium kluyveri DSM 555 Gene: CKL_0201: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium sp. SS2/1 Gene: CLOSS21_00209: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium cellulolyticum H10 Gene: Ccel_3324: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium phytofermentans ISDg Gene: null: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium tetani E88 Gene: CTC02622: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium acetobutylicum ATCC 824 Gene: CAC3177: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium botulinum A str. ATCC 3502 Gene: CBO3501: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium novyi NT Gene: NT01CX_1093: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium perfringens ATCC 13124 Gene: CPF_2737: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium difficile 630 Gene: CD0052: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0131: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium sp. OhILAs Gene: Clos_0469: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium sp. L2-50 Gene: CLOL250_00902: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01226: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium nexile DSM 1787 Gene: CLONEX_00246: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium leptum DSM 753 Gene: CLOLEP_01987: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01557: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium butyricum 5521 Gene: CBY_2150: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02763: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00070: Cysteinyl-tRNA synthetase (EC 6.1.1.16)	Cysteinyl-tRNA synthetase (EC 6.1.1.16)

CRON 2.
cysP1	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC02307: Cystine uptake protein CysP	Clostridium acetobutylicum ATCC 824	* Clostridium botulinum A str. ATCC 3502 Site: position = -395 score = 87.29 sequence = ATTAAAAGCTATGAA... Gene: CBO0235: Cystine uptake protein CysP	Clostridium novyi NT Gene: NT01CX_2260: Cystine uptake protein CysP	* Clostridium perfringens ATCC 13124 Site: position = -331 score = 67.64 sequence = GAAAAGCTGTGATTA... Gene: CPF_1223: Cystine uptake protein CysP	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_02148: Cystine uptake protein CysP	Clostridium nexile DSM 1787 Gene: CLONEX_00437: Cystine uptake protein CysP	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05337: Cystine uptake protein CysP	Clostridium bartlettii DSM 16795	Cystine uptake protein CysP
cysP2	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_00450: Cystine uptake protein CysP	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Cystine uptake protein CysP	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	* Clostridium perfringens ATCC 13124 Site: position = -376 score = 104.21 sequence = TAAATGCGTTGAAGA... Gene: CPF_1191: Cystine uptake protein CysP	Clostridium difficile 630 Gene: CD2541: Cystine uptake protein CysP	Clostridium beijerincki NCIMB 8052 Gene: Cbei_4344: Cystine uptake protein CysP	Clostridium sp. OhILAs Gene: Clos_0824: Cystine uptake protein CysP	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01037: Cystine uptake protein CysP	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01036: Cystine uptake protein CysP	Cystine uptake protein CysP

CRON 3.
tcyA	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	* Clostridium acetobutylicum ATCC 824 Site: position = -327 score = 87.38 sequence = GATTTGCTAGGATAA... Gene: CAC3325: L-Cystine ABC transporter, periplasmic cystine-binding protein TcyA	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_06445: L-Cystine ABC transporter, periplasmic cystine-binding protein TcyA	Clostridium bartlettii DSM 16795	L-Cystine ABC transporter, periplasmic cystine-binding protein TcyA
tcyB	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3326: L-Cystine ABC transporter, permease protein TcyB	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_06446: L-Cystine ABC transporter, permease protein TcyB	Clostridium bartlettii DSM 16795	L-Cystine ABC transporter, permease protein TcyB
tcyC	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3327: L-Cystine ABC transporter, ATP-binding protein TcyC	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_06447: L-Cystine ABC transporter, ATP-binding protein TcyC	Clostridium bartlettii DSM 16795	L-Cystine ABC transporter, ATP-binding protein TcyC

CRON 4.
ubiG	* Clostridium kluyveri DSM 555 Site: position = -370 score = 84.03 sequence = TAATTGCGATGATGA... Gene: CKL_1001: SAM-dependent methlytransferase UbiG	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	* Clostridium acetobutylicum ATCC 824 Site: position = -377 score = 98.11 sequence = TAAATACTGTGATAA... Gene: CAC0929: SAM-dependent methlytransferase UbiG	* Clostridium botulinum A str. ATCC 3502 Site: position = -407 score = 98.63 sequence = GATAAATGCTATGAT... Gene: CBO0727: SAM-dependent methlytransferase UbiG	Clostridium novyi NT	* Clostridium perfringens ATCC 13124 Site: position = -380 score = 131.38 sequence = TAAATGCATTGAAAA... Gene: CPF_0168: SAM-dependent methlytransferase UbiG	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_1076: SAM-dependent methlytransferase UbiG	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	SAM-dependent methlytransferase UbiG
mccB	Clostridium kluyveri DSM 555 Gene: CKL_1002: Cystathionine gamma-lyase (EC 4.4.1.1)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Cystathionine gamma-lyase (EC 4.4.1.1)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC0930: Cystathionine gamma-lyase (EC 4.4.1.1)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0726: Cystathionine gamma-lyase (EC 4.4.1.1)	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_0169: Cystathionine gamma-lyase (EC 4.4.1.1)	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0629: Cystathionine gamma-lyase (EC 4.4.1.1)	Clostridium sp. OhILAs Gene: Clos_1074: Cystathionine gamma-lyase (EC 4.4.1.1)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_1162: Cystathionine gamma-lyase (EC 4.4.1.1)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Cystathionine gamma-lyase (EC 4.4.1.1)
mccA	Clostridium kluyveri DSM 555 Gene: CKL_1003: Cystathionine beta-synthase (EC 4.2.1.22)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Cystathionine beta-synthase (EC 4.2.1.22)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC0931: Cystathionine beta-synthase (EC 4.2.1.22)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0724: Cystathionine beta-synthase (EC 4.2.1.22)	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_0170: Cystathionine beta-synthase (EC 4.2.1.22)	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0630: Cystathionine beta-synthase (EC 4.2.1.22)	Clostridium sp. OhILAs Gene: Clos_1073: Cystathionine beta-synthase (EC 4.2.1.22)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_1163: Cystathionine beta-synthase (EC 4.2.1.22)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Cystathionine beta-synthase (EC 4.2.1.22)
luxS	Clostridium kluyveri DSM 555 Gene: CKL_1558: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC2942: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0725: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_0171: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium difficile 630 Gene: CD3598: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1237: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium sp. OhILAs Gene: Clos_1075: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium sp. L2-50 Gene: CLOL250_01391: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium scindens ATCC 35704 Gene: CLOSCI_01289: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium nexile DSM 1787 Gene: CLONEX_03062: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium leptum DSM 753 Gene: CLOLEP_00535: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_02203: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium butyricum 5521 Gene: CBY_0312: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01686: S-ribosylhomocysteine lyase (EC 4.4.1.21)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00200: S-ribosylhomocysteine lyase (EC 4.4.1.21)	S-ribosylhomocysteine lyase (EC 4.4.1.21)