Regulog T-box(His) - Streptococcaceae

Properties
Regulator type:	RNA regulatory element
Name:	T-box
RFAM:	RF00230
Regulation mode:
Biological process:	Amino acid metabolism
Effector:	His-tRNA
Phylum:	Firmicutes

Member of regulog collections

By taxonomy - Streptococcaceae
By RNA motif - T-box
By effector - His-tRNA
By pathway - Amino acid metabolism

Statistics of regulated genes
Genome	Genes	Operons
Streptococcus pneumoniae TIGR4
Streptococcus gallolyticus UCN34	11	1
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Streptococcus suis 05ZYH33
Lactococcus lactis subsp. lactis Il1403	11	1
Lactococcus lactis subsp. cremoris SK11	11	1
Streptococcus uberis 0140J
Streptococcus agalactiae 2603V/R
Streptococcus sanguinis SK36	11	1
Streptococcus pyogenes M1 GAS
Streptococcus mutans UA159	13	1
Streptococcus thermophilus CNRZ1066
Streptococcus gordonii str. Challis substr. CH1	13	2
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus mitis B6

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
hisC	Streptococcus pneumoniae TIGR4	2 Streptococcus gallolyticus UCN34* Site: position = -291 score = 74.78 sequence = TATAAAAGTGTTGAT... Gene: GALLO_1473: Histidinol-phosphate aminotransferase (EC 2.6.1.9) Gene: GALLO_0847: Histidinol-phosphate aminotransferase (EC 2.6.1.9)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	* Lactococcus lactis subsp. lactis Il1403 Site: position = -271 score = 83.21 sequence = CGAGAGATGAAAAGA... Gene: L0065: Histidinol-phosphate aminotransferase (EC 2.6.1.9)	* Lactococcus lactis subsp. cremoris SK11 Site: position = -284 score = 80.98 sequence = AAACAAGAGATGAAA... Gene: LACR_1336: Histidinol-phosphate aminotransferase (EC 2.6.1.9)	Streptococcus uberis 0140J Gene: SUB0639: Histidinol-phosphate aminotransferase (EC 2.6.1.9)	Streptococcus agalactiae 2603V/R	* Streptococcus sanguinis SK36 Site: position = -387 score = 70.84 sequence = ATTGAAAGCGATGAG... Gene: SSA_1449: Histidinol-phosphate aminotransferase (EC 2.6.1.9)	Streptococcus pyogenes M1 GAS	* Streptococcus mutans UA159 Site: position = -277 score = 70.07 sequence = TAGAAAAGCGATGAG... Gene: SMU.1273: Histidinol-phosphate aminotransferase (EC 2.6.1.9)	Streptococcus thermophilus CNRZ1066	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -386 score = 69.94 sequence = ATCGAAAGCGATGAG... Gene: SGO_1411: Histidinol-phosphate aminotransferase (EC 2.6.1.9)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Histidinol-phosphate aminotransferase (EC 2.6.1.9)
hisZ	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_1472: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0341: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1335: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36 Gene: SSA_1448: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1272: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1410: ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)
hisG	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_1471: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0066: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)	Lactococcus lactis subsp. cremoris SK11	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36 Gene: SSA_1447: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1271: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1409: ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	ATP phosphoribosyltransferase catalytic subunit (EC 2.4.2.17)
hisD	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_1470: Histidinol dehydrogenase (EC 1.1.1.23)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0067: Histidinol dehydrogenase (EC 1.1.1.23)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1332: Histidinol dehydrogenase (EC 1.1.1.23)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36 Gene: SSA_1446: Histidinol dehydrogenase (EC 1.1.1.23)	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1270: Histidinol dehydrogenase (EC 1.1.1.23)	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1408: Histidinol dehydrogenase (EC 1.1.1.23)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Histidinol dehydrogenase (EC 1.1.1.23)
serB	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_1469: Phosphoserine phosphatase (EC 3.1.3.3)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403	Lactococcus lactis subsp. cremoris SK11	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1269: Phosphoserine phosphatase (EC 3.1.3.3)	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Phosphoserine phosphatase (EC 3.1.3.3)
hisB	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_1468: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0068: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1331: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36 Gene: SSA_1445: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1268: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1407: Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)
SMU.1267c	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403	Lactococcus lactis subsp. cremoris SK11	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1267c: hypothetical protein	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	hypothetical protein
hisH	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_1467: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0069: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1329: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36 Gene: SSA_1444: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1266: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1406: Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)
hisA	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_1466: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0070: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1328: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36 Gene: SSA_1443: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1265: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1405: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)
hisF	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_1465: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0071: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1327: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36 Gene: SSA_1442: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1264: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1404: Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
hisI	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_1464: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403	Lactococcus lactis subsp. cremoris SK11	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36 Gene: SSA_1441: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1263: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1403: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)
SGO_0638	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403	Lactococcus lactis subsp. cremoris SK11	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1262c: hypothetical protein	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_0638: hypothetical protein	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	hypothetical protein
hisE	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_1463: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403	Lactococcus lactis subsp. cremoris SK11	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36 Gene: SSA_1440: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1261c: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1402: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
hisK	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34 Gene: GALLO_0805: Histidinol-phosphatase (EC 3.1.3.15)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L37351: Histidinol-phosphatase (EC 3.1.3.15)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1325: Histidinol-phosphatase (EC 3.1.3.15)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36 Gene: SSA_1439: Histidinol-phosphatase (EC 3.1.3.15)	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159 Gene: SMU.1486c: Histidinol-phosphatase (EC 3.1.3.15)	Streptococcus thermophilus CNRZ1066 Gene: str1232: Histidinol-phosphatase (EC 3.1.3.15)	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1401: Histidinol-phosphatase (EC 3.1.3.15)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Histidinol-phosphatase (EC 3.1.3.15)
ymdC	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L33782: Probable aminoglycoside 3'-phosphotransferase (EC 2.7.1.95) (Kanamycin kinase)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1330: Probable aminoglycoside 3'-phosphotransferase (EC 2.7.1.95) (Kanamycin kinase)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Probable aminoglycoside 3'-phosphotransferase (EC 2.7.1.95) (Kanamycin kinase)
his(I/E)	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0072: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1326: Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) / Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
LACR_1334	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1334: hypothetical protein	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	hypothetical protein
SGO_0637	Streptococcus pneumoniae TIGR4	Streptococcus gallolyticus UCN34	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403	Lactococcus lactis subsp. cremoris SK11	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159	Streptococcus thermophilus CNRZ1066	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -314 score = 51.67 sequence = TATGTTCATCAGAGG... Gene: SGO_0637: Acetyltransferase (EC 2.3.1.-)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Acetyltransferase (EC 2.3.1.-)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog T-box(His) - Streptococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --