Regulog FMN - Streptococcaceae

Properties
Regulator type:	RNA regulatory element
Name:	FMN
RFAM:	RF00050
Regulation mode:
Biological process:	Riboflavin biosynthesis
Effector:	Flavin mononucleotide
Phylum:	Firmicutes

Member of regulog collections

By taxonomy - Streptococcaceae
By RNA motif - FMN
By effector - Flavin mononucleotide
By pathway - Riboflavin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Streptococcus pneumoniae TIGR4	6	2
Streptococcus gallolyticus UCN34	5	2
Streptococcus dysgalactiae subsp. equisimilis GGS_124	2	1
Streptococcus suis 05ZYH33	1	1
Lactococcus lactis subsp. lactis Il1403	5	2
Lactococcus lactis subsp. cremoris SK11	1	1
Streptococcus uberis 0140J	2	1
Streptococcus agalactiae 2603V/R	6	2
Streptococcus sanguinis SK36	2	1
Streptococcus pyogenes M1 GAS	2	1
Streptococcus mutans UA159	2	1
Streptococcus thermophilus CNRZ1066	2	1
Streptococcus gordonii str. Challis substr. CH1	2	1
Streptococcus equi subsp. zooepidemicus MGCS10565	2	1
Streptococcus mitis B6	2	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
ribD	* Streptococcus pneumoniae TIGR4 Site: position = -249 score = 123.67 sequence = TAACTATCTTCAGGG... Gene: SP_0178: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	* Streptococcus gallolyticus UCN34 Site: position = -365 score = 52.21 sequence = TATGTCTGCGAGGTG... Gene: GALLO_0692: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	* Lactococcus lactis subsp. lactis Il1403 Site: position = -298 score = 118.78 sequence = TAAATCTTCAGGGCA... Gene: L0163: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	Lactococcus lactis subsp. cremoris SK11	Streptococcus uberis 0140J	* Streptococcus agalactiae 2603V/R Site: position = -307 score = 108.7 sequence = AATTTCTTCGGGGTC... Gene: SAG0746: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
ribE	Streptococcus pneumoniae TIGR4 Gene: SP_0177: Riboflavin synthase alpha chain (EC 2.5.1.9)	Streptococcus gallolyticus UCN34 Gene: GALLO_0693: Riboflavin synthase alpha chain (EC 2.5.1.9)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0164: Riboflavin synthase alpha chain (EC 2.5.1.9)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1073: Riboflavin synthase alpha chain (EC 2.5.1.9)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R Gene: SAG0747: Riboflavin synthase alpha chain (EC 2.5.1.9)	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	Riboflavin synthase alpha chain (EC 2.5.1.9)
ribBA	Streptococcus pneumoniae TIGR4 Gene: SP_0176: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Streptococcus gallolyticus UCN34 Gene: GALLO_0694: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0165: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1074: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R Gene: SAG0748: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
ribH	Streptococcus pneumoniae TIGR4 Gene: SP_0175: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Streptococcus gallolyticus UCN34 Gene: GALLO_0695: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus suis 05ZYH33	Lactococcus lactis subsp. lactis Il1403 Gene: L0166: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Lactococcus lactis subsp. cremoris SK11 Gene: LACR_1075: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Streptococcus uberis 0140J	Streptococcus agalactiae 2603V/R Gene: SAG0749: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)	Streptococcus sanguinis SK36	Streptococcus pyogenes M1 GAS	Streptococcus mutans UA159	Streptococcus thermophilus CNRZ1066	Streptococcus gordonii str. Challis substr. CH1	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus mitis B6	6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)

CRON 2.
ribU	* Streptococcus pneumoniae TIGR4 Site: position = -249 score = 52.01 sequence = CTTCTCTTTAAAGAA... Gene: SP_0488: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus gallolyticus UCN34 Site: position = -194 score = 47.71 sequence = ACTTAGTTAGTTTAG... Gene: GALLO_1792: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -202 score = 119.86 sequence = AGTGTCTTCAGGGCA... Gene: SDEG_0423: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus suis 05ZYH33 Site: position = -218 score = 76.4 sequence = TTCAAGGCAGGGTGA... Gene: SSU05_1696: Substrate-specific component RibU of riboflavin ECF transporter	* Lactococcus lactis subsp. lactis Il1403 Site: position = -252 score = 99.77 sequence = AAAATATCTTCAGGG... Gene: L106755: Substrate-specific component RibU of riboflavin ECF transporter	* Lactococcus lactis subsp. cremoris SK11 Site: position = -252 score = 100.36 sequence = AAAATATCTTCAGGG... Gene: LACR_1395: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus uberis 0140J Site: position = -201 score = 121.23 sequence = AGTGTCTTCAGGGCA... Gene: SUB0410: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus agalactiae 2603V/R Site: position = -215 score = 115.01 sequence = TAGGTGTCTTCAGGG... Gene: SAG1403: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus sanguinis SK36 Site: position = -281 score = 111.17 sequence = ATGATGTCTTCAGGG... Gene: SSA_1773: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus pyogenes M1 GAS Site: position = -201 score = 114.42 sequence = AGTGTCTTCAGGGCA... Gene: SPy0373: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus mutans UA159 Site: position = -323 score = 81.85 sequence = CTTCAGGGCAGGGTG... Gene: SMU.1703c: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus thermophilus CNRZ1066 Site: position = -126 score = 110.85 sequence = AGGGTCTTCGGGGCA... Gene: str0268: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -283 score = 111.31 sequence = AAAGAGTCTTCAGGG... Gene: SGO_1664: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -175 score = 114.76 sequence = TAAGTGTCTTCAGGG... Gene: Sez_1631: Substrate-specific component RibU of riboflavin ECF transporter	* Streptococcus mitis B6 Site: position = -250 score = 52.02 sequence = TCCTTCTCTTTAAAG... Gene: smi_1807: Substrate-specific component RibU of riboflavin ECF transporter	Substrate-specific component RibU of riboflavin ECF transporter
SP_0489	Streptococcus pneumoniae TIGR4 Gene: SP_0489: Membrane-associated phospholipid phosphatase	Streptococcus gallolyticus UCN34 Gene: GALLO_1789: Membrane-associated phospholipid phosphatase	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0424: Membrane-associated phospholipid phosphatase	Streptococcus suis 05ZYH33 Gene: SSU05_1694: Membrane-associated phospholipid phosphatase	Lactococcus lactis subsp. lactis Il1403	Lactococcus lactis subsp. cremoris SK11	Streptococcus uberis 0140J Gene: SUB0411: Membrane-associated phospholipid phosphatase	Streptococcus agalactiae 2603V/R Gene: SAG1402: Membrane-associated phospholipid phosphatase	Streptococcus sanguinis SK36 Gene: SSA_1772: Membrane-associated phospholipid phosphatase	Streptococcus pyogenes M1 GAS Gene: SPy0374: Membrane-associated phospholipid phosphatase	Streptococcus mutans UA159 Gene: SMU.1702c: Membrane-associated phospholipid phosphatase	Streptococcus thermophilus CNRZ1066 Gene: str0269: Membrane-associated phospholipid phosphatase	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1663: Membrane-associated phospholipid phosphatase	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_1630: Membrane-associated phospholipid phosphatase	Streptococcus mitis B6 Gene: smi_1806: Membrane-associated phospholipid phosphatase	Membrane-associated phospholipid phosphatase

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog FMN - Streptococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --