Regulog TPP - Streptococcaceae
| Regulator type: | RNA regulatory element |
| Name: | TPP |
| RFAM: | RF00059 |
| Regulation mode: | |
| Biological process: | Thiamine biosynthesis |
| Effector: | Thiamine pyrophosphate |
| Phylum: | Firmicutes |
Member of regulog collections
- By taxonomy - Streptococcaceae
- By RNA motif - TPP
- By effector - Thiamine pyrophosphate
- By pathway - Thiamine biosynthesis
| Genes | Function | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||||||||||
| thiT |
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*
Streptococcus gallolyticus UCN34 Site: position = -174 score = 71.14 sequence = TAGATTCACAAAGGA... Gene: GALLO_0703: Substrate-specific component ThiT of thiamin ECF transporter |
*
Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -112 score = 67.67 sequence = ATGATTCACAAAGGA... Gene: SDEG_0615: Substrate-specific component ThiT of thiamin ECF transporter |
*
Streptococcus suis 05ZYH33 Site: position = -155 score = 66.39 sequence = CATATACACAAAGGA... Gene: SSU05_0523: Substrate-specific component ThiT of thiamin ECF transporter |
*
Lactococcus lactis subsp. lactis Il1403 Site: position = -120 score = 55.63 sequence = ATATTTGCACAATGG... Gene: L116212: Substrate-specific component ThiT of thiamin ECF transporter |
*
Lactococcus lactis subsp. cremoris SK11 Site: position = -147 score = 55.47 sequence = ATATTTGCACAATGG... Gene: LACR_0359: Substrate-specific component ThiT of thiamin ECF transporter |
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Streptococcus uberis 0140J Site: position = -150 score = 68.62 sequence = ATATTTCACAAAGGA... Gene: SUB0597: Substrate-specific component ThiT of thiamin ECF transporter |
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Streptococcus agalactiae 2603V/R Site: position = -157 score = 58.74 sequence = TAAATACACAAGGGA... Gene: SAG0817: Substrate-specific component ThiT of thiamin ECF transporter |
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*
Streptococcus pyogenes M1 GAS Site: position = -142 score = 70.23 sequence = ATATTTCACAAAGGA... Gene: SPy0600: Substrate-specific component ThiT of thiamin ECF transporter |
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Streptococcus mutans UA159 Site: position = -111 score = 77.59 sequence = TAAATATCACAAGGA... Gene: SMU.706c: Substrate-specific component ThiT of thiamin ECF transporter |
*
Streptococcus thermophilus CNRZ1066 Site: position = -197 score = 59.23 sequence = AGAGTCACAAGAGGA... Gene: str1571: Substrate-specific component ThiT of thiamin ECF transporter |
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*
Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -144 score = 71.89 sequence = AATTATCACAAAGGA... Gene: Sez_0708: Substrate-specific component ThiT of thiamin ECF transporter |
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Substrate-specific component ThiT of thiamin ECF transporter |
| CRON 2. | ||||||||||||||||
| thiW |
Gene: SP_0723: Substrate-specific component ThiW of predicted thiazole ECF transporter |
*
Streptococcus gallolyticus UCN34 Site: position = -267 score = 63.44 sequence = ATAAAGACATTTGGG... Gene: GALLO_1184: Substrate-specific component ThiW of predicted thiazole ECF transporter |
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Streptococcus agalactiae 2603V/R Site: position = -244 score = 60.3 sequence = TAGGACATTTGGGGT... Gene: SAG0835: Substrate-specific component ThiW of predicted thiazole ECF transporter |
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Substrate-specific component ThiW of predicted thiazole ECF transporter |
| ykoE |
*
Streptococcus pneumoniae TIGR4 Site: position = -349 score = 67.67 sequence = AAAGACATTTGGGGT... Gene: SP_0719: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: SAG0836: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| ykoD |
Gene: SP_0720: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: SAG0837: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| ykoC |
Gene: SP_0721: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: SAG0838: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| tenA |
*2
Streptococcus pneumoniae TIGR4 Site: position = -302 score = 68.17 sequence = AGAGACATTTGGGGT... Gene: SP_0716: Thiaminase II (EC 3.5.99.2) Gene: SP_0722: Thiaminase II (EC 3.5.99.2) |
Gene: GALLO_1181: Thiaminase II (EC 3.5.99.2) |
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Gene: L0228: Thiaminase II (EC 3.5.99.2) |
Gene: LACR_1950: Thiaminase II (EC 3.5.99.2) |
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Gene: SAG0839: Thiaminase II (EC 3.5.99.2) |
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Thiaminase II (EC 3.5.99.2) |
| thiD |
*
Streptococcus pneumoniae TIGR4 Site: position = -183 score = 59.01 sequence = AAACAACCACTAGGG... Gene: SP_0726: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: GALLO_1180: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
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Gene: SSU05_0733: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: L0200: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: LACR_1376: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
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Gene: SAG0840: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
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Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
| thiM |
2
Streptococcus pneumoniae TIGR4 Gene: SP_0717: Hydroxyethylthiazole kinase (EC 2.7.1.50) Gene: SP_0724: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Gene: GALLO_1179: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Gene: SSU05_0734: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
*
Lactococcus lactis subsp. lactis Il1403 Site: position = -184 score = 55.02 sequence = TCAATAACACAATGG... Gene: L94809: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
*
Lactococcus lactis subsp. cremoris SK11 Site: position = -183 score = 52.64 sequence = TCTAATACACAATGG... Gene: LACR_1377: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Gene: SAG0841: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Hydroxyethylthiazole kinase (EC 2.7.1.50) |
| thiE |
2
Streptococcus pneumoniae TIGR4 Gene: SP_0718: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) Gene: SP_0725: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: GALLO_1178: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
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Gene: SSU05_0735: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: L0201: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: LACR_1375: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
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Gene: SAG0842: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
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Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
| GALLO_1183 |
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Gene: GALLO_1183: hypothetical protein |
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hypothetical protein |
| SSU05_0732 |
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Gene: GALLO_1182: putative HAD-superfamily hydrolase / phosphatase |
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*
Streptococcus suis 05ZYH33 Site: position = -423 score = 68.32 sequence = TAGAACATTTGGGGT... Gene: SSU05_0732: putative HAD-superfamily hydrolase / phosphatase |
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putative HAD-superfamily hydrolase / phosphatase |
| CRON 3. | ||||||||||||||||
| COG0011 |
*
Streptococcus pneumoniae TIGR4 Site: position = -174 score = 47.78 sequence = ACATATAATATATGG... Gene: SP_2199: Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family |
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*
Streptococcus gordonii str. Challis substr. CH1 Site: position = -327 score = 51.89 sequence = AATATACATATATGG... Gene: SGO_2102: Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family |
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*
Streptococcus mitis B6 Site: position = -172 score = 49.96 sequence = CTATATAATATATGG... Gene: smi_2050: Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family |
Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family |
| thiX |
Gene: SP_2198: Thiamin ABC transporter, transmembrane component |
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*
Streptococcus sanguinis SK36 Site: position = -216 score = 43.99 sequence = TCCTATATATGGGAG... Gene: SSA_2353: Thiamin ABC transporter, transmembrane component |
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Gene: SGO_2101: Thiamin ABC transporter, transmembrane component |
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Gene: smi_2049: Thiamin ABC transporter, transmembrane component |
Thiamin ABC transporter, transmembrane component |
| thiY |
Gene: SP_2197: Thiamin ABC transporter, substrate-binding component |
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Gene: SSA_2352: Thiamin ABC transporter, substrate-binding component |
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Gene: SGO_2100: Thiamin ABC transporter, substrate-binding component |
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Gene: smi_2048: Thiamin ABC transporter, substrate-binding component |
Thiamin ABC transporter, substrate-binding component |
| thiZ |
Gene: SP_2196: Thiamin ABC transporter, ATPase component |
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Gene: SSA_2351: Thiamin ABC transporter, ATPase component |
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Gene: SGO_2099: Thiamin ABC transporter, ATPase component |
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Gene: smi_2047: Thiamin ABC transporter, ATPase component |
Thiamin ABC transporter, ATPase component |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |