Regulog BirA - Desulfuromonadales

Properties
Regulator type:	Transcription factor
Regulator family:	BirA
Regulation mode:	repressor
Biological process:	Biotin biosynthesis
Effector:	Biotin
Phylum:	Proteobacteria/delta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 15 sites [see more]

Member of regulog collections

By taxonomy - Desulfuromonadales
By trascription factor - BirA
By TF family - BirA
By effector - Biotin
By pathway - Biotin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Geobacter metallireducens GS-15	6	2
Geobacter sulfurreducens PCA	6	2
Geobacter uraniumreducens Rf4	6	2
Geobacter sp. FRC-32	6	2
Geobacter sp. M21	6	2
Geobacter lovleyi SZ	5	2
Pelobacter propionicus DSM 2379	3	1
Pelobacter carbinolicus str. DSM 2380	7	2
Desulfuromonas acetoxidans DSM 684

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
bioB	* Geobacter metallireducens GS-15 Site: position = -75 score = 7.93146 sequence = TTGTTAACC-(14)-AGTTGACAA Gene: Gmet_1582: Biotin synthase (EC 2.8.1.6)	* Geobacter sulfurreducens PCA Site: position = -79 score = 8.59468 sequence = TTGTCAACC-(14)-AGTTGACAA Gene: GSU1584: Biotin synthase (EC 2.8.1.6)	* Geobacter uraniumreducens Rf4 Site: position = -74 score = 8.3816 sequence = TCGTCAACC-(14)-GGTTGACAA Gene: Gura_2242: Biotin synthase (EC 2.8.1.6)	* Geobacter sp. FRC-32 Site: position = -74 score = 8.3816 sequence = TCGTCAACC-(14)-GGTTGACAA Gene: Geob_3008: Biotin synthase (EC 2.8.1.6)	* Geobacter sp. M21 Site: position = -72 score = 8.3816 sequence = TCGTCAACC-(14)-GGTTGACAA Gene: GM21_2164: Biotin synthase (EC 2.8.1.6)	* Geobacter lovleyi SZ Site: position = -63 score = 9.02294 sequence = TTGTCAACC-(15)-GGTTGACAA Gene: Glov_2370: Biotin synthase (EC 2.8.1.6)	Pelobacter propionicus DSM 2379 Gene: Ppro_1175: Biotin synthase (EC 2.8.1.6)	* Pelobacter carbinolicus str. DSM 2380 Site: position = -137 score = 8.40466 sequence = TTGTCAACC-(14)-TGTTGACAA Gene: Pcar_1458: Biotin synthase (EC 2.8.1.6)	Desulfuromonas acetoxidans DSM 684	Biotin synthase (EC 2.8.1.6)
bioD	Geobacter metallireducens GS-15 Gene: Gmet_1581: Dethiobiotin synthetase (EC 6.3.3.3)	Geobacter sulfurreducens PCA Gene: GSU1583: Dethiobiotin synthetase (EC 6.3.3.3)	Geobacter uraniumreducens Rf4 Gene: Gura_2243: Dethiobiotin synthetase (EC 6.3.3.3)	Geobacter sp. FRC-32 Gene: Geob_3009: Dethiobiotin synthetase (EC 6.3.3.3)	Geobacter sp. M21 Gene: GM21_2165: Dethiobiotin synthetase (EC 6.3.3.3)	Geobacter lovleyi SZ Gene: Glov_2369: Dethiobiotin synthetase (EC 6.3.3.3)	Pelobacter propionicus DSM 2379 Gene: Ppro_1176: Dethiobiotin synthetase (EC 6.3.3.3)	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_1459: Dethiobiotin synthetase (EC 6.3.3.3)	Desulfuromonas acetoxidans DSM 684	Dethiobiotin synthetase (EC 6.3.3.3)
bioA	Geobacter metallireducens GS-15 Gene: Gmet_1580: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Geobacter sulfurreducens PCA Gene: GSU1582: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Geobacter uraniumreducens Rf4 Gene: Gura_2244: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Geobacter sp. FRC-32 Gene: Geob_3010: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Geobacter sp. M21 Gene: GM21_2166: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Geobacter lovleyi SZ Gene: Glov_2247: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Pelobacter propionicus DSM 2379 Gene: Ppro_1177: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_1460: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Desulfuromonas acetoxidans DSM 684	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)

CRON 2.
bioW	Geobacter metallireducens GS-15	Geobacter sulfurreducens PCA	Geobacter uraniumreducens Rf4	Geobacter sp. FRC-32	Geobacter sp. M21	Geobacter lovleyi SZ	Pelobacter propionicus DSM 2379	* Pelobacter carbinolicus str. DSM 2380 Site: position = -62 score = 8.22649 sequence = ATGTCAACC-(14)-TGTTGACAA Gene: Pcar_1666: Pimeloyl-CoA synthase (EC 6.2.1.14)	Desulfuromonas acetoxidans DSM 684	Pimeloyl-CoA synthase (EC 6.2.1.14)
bioF	* Geobacter metallireducens GS-15 Site: position = -65 score = 8.3816 sequence = TTGTCAACC-(14)-GGTTGACGA Gene: Gmet_0842: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	* Geobacter sulfurreducens PCA Site: position = -87 score = 8.3816 sequence = TTGTCAACC-(14)-GGTTGACGA Gene: GSU2629: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	* Geobacter uraniumreducens Rf4 Site: position = -94 score = 7.71838 sequence = TTGTTAACC-(14)-GGTTGACGA Gene: Gura_3246: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	* Geobacter sp. FRC-32 Site: position = -90 score = 7.07703 sequence = TCGTTAACC-(14)-GGTTGACGA Gene: Geob_2084: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	* Geobacter sp. M21 Site: position = -102 score = 8.3816 sequence = TTGTCAACC-(14)-GGTTGACGA Gene: GM21_3430: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	* Geobacter lovleyi SZ Site: position = -32 score = 7.93146 sequence = TTGTCAACT-(15)-GGTTAACAA Gene: Glov_1662: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	* Pelobacter propionicus DSM 2379 Site: position = -42 score = 7.95333 sequence = TTGTCAACT-(14)-GGTTGACCA Gene: Ppro_2093: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_1665: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Desulfuromonas acetoxidans DSM 684	8-amino-7-oxononanoate synthase (EC 2.3.1.47)
bioH	Geobacter metallireducens GS-15 Gene: Gmet_0843: Biotin synthesis protein bioH	Geobacter sulfurreducens PCA Gene: GSU2628: Biotin synthesis protein bioH	Geobacter uraniumreducens Rf4 Gene: Gura_3245: Biotin synthesis protein bioH	Geobacter sp. FRC-32 Gene: Geob_2085: Biotin synthesis protein bioH	Geobacter sp. M21 Gene: GM21_3429: Biotin synthesis protein bioH	Geobacter lovleyi SZ Gene: Glov_1663: Biotin synthesis protein bioH	Pelobacter propionicus DSM 2379 Gene: Ppro_2092: Biotin synthesis protein bioH	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_1664: Biotin synthesis protein bioH	Desulfuromonas acetoxidans DSM 684	Biotin synthesis protein bioH
bioC	Geobacter metallireducens GS-15 Gene: Gmet_0844: Biotin synthesis protein bioC	Geobacter sulfurreducens PCA Gene: GSU2627: Biotin synthesis protein bioC	Geobacter uraniumreducens Rf4 Gene: Gura_3244: Biotin synthesis protein bioC	Geobacter sp. FRC-32 Gene: Geob_2086: Biotin synthesis protein bioC	Geobacter sp. M21 Gene: GM21_3428: Biotin synthesis protein bioC	Geobacter lovleyi SZ Gene: Glov_1664: Biotin synthesis protein bioC	Pelobacter propionicus DSM 2379 Gene: Ppro_2091: Biotin synthesis protein bioC	Pelobacter carbinolicus str. DSM 2380 Gene: Pcar_1663: Biotin synthesis protein bioC	Desulfuromonas acetoxidans DSM 684	Biotin synthesis protein bioC

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog BirA - Desulfuromonadales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --