Regulog NsrR - Rhodobacterales

Properties
Regulator type:	Transcription factor
Regulator family:	Rrf2
Regulation mode:	repressor
Biological process:	Nitrosative stress response
Effector:	Nitric oxide
Phylum:	Proteobacteria/alpha
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 17 sites [see more]

Member of regulog collections

By trascription factor - NsrR
By taxonomy - Rhodobacterales
By TF family - Rrf2
By effector - Nitric oxide
By pathway - Nitrosative stress response

Statistics of regulated genes
Genome	Genes	Operons
Rhodobacter sphaeroides 2.4.1
Paracoccus denitrificans PD1222	5	4
Jannaschia sp. CCS1
Rhodobacterales bacterium HTCC2654
Oceanicola granulosus HTCC2516
Loktanella vestfoldensis SKA53
Oceanicola batsensis HTCC2597	2	2
Roseovarius nubinhibens ISM
Roseovarius sp. 217	11	4
Sulfitobacter sp. EE-36
Silicibacter TM1040
Silicibacter pomeroyi DSS-3	12	3
Roseobacter sp. MED193
Hyphomonas neptunium ATCC 15444	3	2
Oceanicaulis alexandrii HTCC2633

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
hmp	Rhodobacter sphaeroides 2.4.1	* Paracoccus denitrificans PD1222 Site: position = -71 score = 4.73051 sequence = GATGTATCCAGAATACATG Gene: Pden_1689: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
Pden_1688	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222 Gene: Pden_1688: hypothetical protein	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444 Gene: HNE_1549: hypothetical protein	Oceanicaulis alexandrii HTCC2633	hypothetical protein

CRON 2.
nsrR2	Rhodobacter sphaeroides 2.4.1	* Paracoccus denitrificans PD1222 Site: position = -73 score = 4.73051 sequence = CATGTATTCTGGATACATC Gene: Pden_1690: Nitrite-sensitive transcriptional repressor NsrR	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	Nitrite-sensitive transcriptional repressor NsrR

CRON 3.
PF01812	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222 Gene: Pden_4790: 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)	Jannaschia sp. CCS1 Gene: Jann_3386: 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516 Gene: OG2516_11011: 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)	Loktanella vestfoldensis SKA53	2 Oceanicola batsensis HTCC2597 Gene: OB2597_05320: 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) Gene: OB2597_08274: 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)	Roseovarius nubinhibens ISM Gene: ISM_00195: 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)	* Roseovarius sp. 217 Site: position = -94 score = 6.35552 sequence = TCGGTATTTACAATACCTA Gene: ROS217_14296: 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444 Gene: HNE_2602: 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)	Oceanicaulis alexandrii HTCC2633 Gene: OA2633_07539: 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)	5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2)
nnrS	Rhodobacter sphaeroides 2.4.1 Gene: RSP_0328: NnrS protein involved in response to NO	Paracoccus denitrificans PD1222 Gene: Pden_4230: NnrS protein involved in response to NO	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654 Gene: RB2654_12759: NnrS protein involved in response to NO	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217 Gene: ROS217_14301: NnrS protein involved in response to NO	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444 Gene: HNE_1556: NnrS protein involved in response to NO	Oceanicaulis alexandrii HTCC2633	NnrS protein involved in response to NO
nnrU	Rhodobacter sphaeroides 2.4.1 Gene: RSP_0318: NnrU family protein, required for expression of nitric oxide and nitrite reductases (Nir and Nor)	Paracoccus denitrificans PD1222 Gene: Pden_2334: NnrU family protein, required for expression of nitric oxide and nitrite reductases (Nir and Nor)	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654 Gene: RB2654_12804: NnrU family protein, required for expression of nitric oxide and nitrite reductases (Nir and Nor)	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217 Gene: ROS217_14306: NnrU family protein, required for expression of nitric oxide and nitrite reductases (Nir and Nor)	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPO1134: NnrU family protein, required for expression of nitric oxide and nitrite reductases (Nir and Nor)	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444 Gene: HNE_1547: NnrU family protein, required for expression of nitric oxide and nitrite reductases (Nir and Nor)	Oceanicaulis alexandrii HTCC2633	NnrU family protein, required for expression of nitric oxide and nitrite reductases (Nir and Nor)

CRON 4.
SPOA0185	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Sulfitobacter sp. EE-36	Silicibacter TM1040	* Silicibacter pomeroyi DSS-3 Site: position = -34 score = 6.38319 sequence = TAGGTATTTAAAATACCTA Gene: SPOA0185: Cytochrome c oxidase (B(O/a)3-type) chain II (EC 1.9.3.1)	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	Cytochrome c oxidase (B(O/a)3-type) chain II (EC 1.9.3.1)
SPOA0184	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPOA0184: Cytochrome c oxidase (B(O/a)3-type) chain I (EC 1.9.3.1)	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	Cytochrome c oxidase (B(O/a)3-type) chain I (EC 1.9.3.1)
SPOA0183	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPOA0183: Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone
SPOA0182	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPOA0182: hypothetical cytochrome oxidase associated membrane protein	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	hypothetical cytochrome oxidase associated membrane protein
SPOA0181	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPOA0181: Formate/nitrite family of transporters	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	Formate/nitrite family of transporters

CRON 5.
PF01152	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	* Oceanicola batsensis HTCC2597 Site: position = -131 score = 5.91313 sequence = TAAGTATTTCCAATACCTA Gene: OB2597_05190: Truncated hemoglobin	Roseovarius nubinhibens ISM	* Roseovarius sp. 217 Site: position = -33 score = 6.35552 sequence = TAGGTATTTACAATACCGA Gene: ROS217_02150: Truncated hemoglobin	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Roseobacter sp. MED193	* Hyphomonas neptunium ATCC 15444 Site: position = -113 score = 6.35552 sequence = TCGGTATTTACAATACCTA Gene: HNE_1540: Truncated hemoglobin	Oceanicaulis alexandrii HTCC2633	Truncated hemoglobin
dnrN	Rhodobacter sphaeroides 2.4.1	* Paracoccus denitrificans PD1222 Site: position = -131 score = 6.14426 sequence = TTGGTATTGACAATACCGA Site: position = -96 score = 5.42129 sequence = TCGGTATTGCAAGTACCGA Gene: Pden_3025: Nitric oxide-dependent regulator DnrN or NorA	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217 Gene: ROS217_02145: Nitric oxide-dependent regulator DnrN or NorA	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444 Gene: HNE_1539: Nitric oxide-dependent regulator DnrN or NorA	Oceanicaulis alexandrii HTCC2633	Nitric oxide-dependent regulator DnrN or NorA

CRON 6.
SPOA0192	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Sulfitobacter sp. EE-36	Silicibacter TM1040	* Silicibacter pomeroyi DSS-3 Site: position = -65 score = 5.23819 sequence = TAGGACTTGAAAATACCTA Gene: SPOA0192: truncated hemoglobin	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	hypothetical protein
ROS217_02185	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPOA0191: membrane protein	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	hypothetical protein
ccoN	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597 Gene: OB2597_20571: Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)	Roseovarius nubinhibens ISM	Roseovarius sp. 217 Gene: ROS217_02160: Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPOA0190: Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)
ccoO	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597 Gene: OB2597_20576: Cytochrome c oxidase subunit CcoO (EC 1.9.3.1)	Roseovarius nubinhibens ISM	Roseovarius sp. 217 Gene: ROS217_02165: Cytochrome c oxidase subunit CcoO (EC 1.9.3.1)	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPOA0189: Cytochrome c oxidase subunit CcoO (EC 1.9.3.1)	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	Cytochrome c oxidase subunit CcoO (EC 1.9.3.1)
ccoQ	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597 Gene: OB2597_20581: Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1)	Roseovarius nubinhibens ISM	Roseovarius sp. 217 Gene: ccoQ: Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1)	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPOA0188: Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1)	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1)
ccoP	Rhodobacter sphaeroides 2.4.1	Paracoccus denitrificans PD1222	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	Oceanicola batsensis HTCC2597 Gene: OB2597_20586: Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)	Roseovarius nubinhibens ISM	Roseovarius sp. 217 Gene: ROS217_02175: Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)	Sulfitobacter sp. EE-36	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPOA0187: Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)	Roseobacter sp. MED193	Hyphomonas neptunium ATCC 15444	Oceanicaulis alexandrii HTCC2633	Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)
nsrR	Rhodobacter sphaeroides 2.4.1	* Paracoccus denitrificans PD1222 Site: position = -66 score = 5.42129 sequence = TCGGTACTTGCAATACCGA Site: position = -31 score = 6.14426 sequence = TCGGTATTGTCAATACCAA Gene: Pden_3024: Nitrite-sensitive transcriptional repressor NsrR	Jannaschia sp. CCS1	Rhodobacterales bacterium HTCC2654	Oceanicola granulosus HTCC2516	Loktanella vestfoldensis SKA53	* Oceanicola batsensis HTCC2597 Site: position = -38 score = 5.91313 sequence = TAGGTATTGGAAATACTTA Gene: OB2597_05195: Nitrite-sensitive transcriptional repressor NsrR	Roseovarius nubinhibens ISM	2 Roseovarius sp. 217* Site: position = -41 score = 6.35552 sequence = TAGGTATTGTAAATACCGA Gene: ROS217_14291: Nitrite-sensitive transcriptional repressor NsrR Site: position = -41 score = 6.35552 sequence = TCGGTATTGTAAATACCTA Gene: ROS217_02155: Nitrite-sensitive transcriptional repressor NsrR	Sulfitobacter sp. EE-36	Silicibacter TM1040	* Silicibacter pomeroyi DSS-3 Site: position = -90 score = 6.38319 sequence = TAGGTATTTTAAATACCTA Gene: SPOA0186: Nitrite-sensitive transcriptional repressor NsrR	Roseobacter sp. MED193	* Hyphomonas neptunium ATCC 15444 Site: position = -40 score = 6.35552 sequence = TAGGTATTGTAAATACCGA Gene: HNE_1541: Nitrite-sensitive transcriptional repressor NsrR	Oceanicaulis alexandrii HTCC2633	Nitrite-sensitive transcriptional repressor NsrR

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NsrR - Rhodobacterales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --