Statistics of regulated genes

Genome	Genes	Operons
Ralstonia eutropha H16	2	2
Cupriavidus taiwanensis	2	2
Ralstonia metallidurans CH34	4	4
Ralstonia eutropha JMP134	2	2
Ralstonia solanacearum GMI1000	8	4
Ralstonia pickettii 12J	9	5

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes							Function
CRON 1.
PHG233	Ralstonia eutropha H16 Gene: PHG233: Hemerythrin HHE cation binding domain protein	Cupriavidus taiwanensis	Ralstonia metallidurans CH34	Ralstonia eutropha JMP134	Ralstonia solanacearum GMI1000	* Ralstonia pickettii 12J Site: position = -102 score = 5.54626 sequence = GATGTATTGTCAATGCATG Gene: Rpic_2508: Hemerythrin HHE cation binding domain protein	Hemerythrin HHE cation binding domain protein
CRON 2.
hmp	* Ralstonia eutropha H16 Site: position = -41 score = 5.63472 sequence = CATGCATTTAATTTGCATG Gene: H16_A3533: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)	* Cupriavidus taiwanensis Site: position = -40 score = 4.62545 sequence = CATGCATATTTTCTGCATG Gene: RALTA_A2986: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)	* Ralstonia metallidurans CH34 Site: position = 32 score = 6.04074 sequence = CATGCATTTTACATGCATG Gene: Rmet_3382: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)	* Ralstonia eutropha JMP134 Site: position = -41 score = 5.47753 sequence = CATGCATTTTGTTTGCATG Gene: Reut_A3219: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)	* Ralstonia solanacearum GMI1000 Site: position = -133 score = 4.32149 sequence = GTGGTATTTAATATGCATG Gene: RS01706: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)	* Ralstonia pickettii 12J Site: position = -32 score = 3.60448 sequence = GTTGCATATTTCACGCATA Gene: Rpic_3609: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)	Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
nnrS	Ralstonia eutropha H16	Cupriavidus taiwanensis	* Ralstonia metallidurans CH34 Site: position = -62 score = 5.5971 sequence = ATTGCATTTAAGATGCATG Gene: Rmet_5307: NnrS protein involved in response to NO	Ralstonia eutropha JMP134	Ralstonia solanacearum GMI1000 Gene: RS01707: NnrS protein involved in response to NO	Ralstonia pickettii 12J Gene: Rpic_3610: NnrS protein involved in response to NO	NnrS protein involved in response to NO
CRON 3.
nsrR	* Ralstonia eutropha H16 Site: position = -39 score = 5.2989 sequence = CTTGCATCCTGGATGCATC Gene: H16_A3534: Nitrite-sensitive transcriptional repressor NsrR	* Cupriavidus taiwanensis Site: position = -40 score = 5.45609 sequence = CTTGCATCCTAGATGCATC Gene: RALTA_A2987: Nitrite-sensitive transcriptional repressor NsrR	* Ralstonia metallidurans CH34 Site: position = -25 score = 5.45773 sequence = CTTGCATTGGCGATGCACG Gene: Rmet_3383: Nitrite-sensitive transcriptional repressor NsrR	* Ralstonia eutropha JMP134 Site: position = -39 score = 4.5798 sequence = CTTGCATTTGAAATGCCGC Gene: Reut_A3220: Nitrite-sensitive transcriptional repressor NsrR	* Ralstonia solanacearum GMI1000 Site: position = -134 score = 4.32149 sequence = CATGCATATTAAATACCAC Gene: RS01705: Nitrite-sensitive transcriptional repressor NsrR	* Ralstonia pickettii 12J Site: position = -218 score = 3.60448 sequence = TATGCGTGAAATATGCAAC Gene: Rpic_3608: Nitrite-sensitive transcriptional repressor NsrR	Nitrite-sensitive transcriptional repressor NsrR
CRON 4.
PF10006	Ralstonia eutropha H16	Cupriavidus taiwanensis	* Ralstonia metallidurans CH34 Site: position = -53 score = 5.60085 sequence = GATGCAATTTAAATGCATC Gene: Rmet_4922: hypothetical protein, PF10006	Ralstonia eutropha JMP134	* Ralstonia solanacearum GMI1000 Site: position = -103 score = 3.68083 sequence = CAAGTATCTGATATACATC Site: position = -53 score = 5.84968 sequence = GATGCATTCTCAATGCATC Gene: RS03037: hypothetical protein, PF10006	* Ralstonia pickettii 12J Site: position = -101 score = 4.31863 sequence = CAAGCATCTGATATACATC Site: position = -51 score = 4.95742 sequence = GTTGCATCCTTAATGCATC Gene: Rpic_4014: hypothetical protein, PF10006	hypothetical protein, PF10006
norB	Ralstonia eutropha H16 Gene: PHG244: Nitric-oxide reductase (EC 1.7.99.7), quinol-dependent	Cupriavidus taiwanensis	Ralstonia metallidurans CH34 Gene: Rmet_3167: Nitric-oxide reductase (EC 1.7.99.7), quinol-dependent	Ralstonia eutropha JMP134	Ralstonia solanacearum GMI1000 Gene: RSp1505: Nitric-oxide reductase (EC 1.7.99.7), quinol-dependent	Ralstonia pickettii 12J Gene: Rpic_4013: Nitric-oxide reductase (EC 1.7.99.7), quinol-dependent	Nitric-oxide reductase (EC 1.7.99.7), quinol-dependent
CRON 5.
nirK	Ralstonia eutropha H16	Cupriavidus taiwanensis	Ralstonia metallidurans CH34	Ralstonia eutropha JMP134	* Ralstonia solanacearum GMI1000 Site: position = -203 score = 5.84968 sequence = GATGCATTGAGAATGCATC Site: position = -153 score = 3.68083 sequence = GATGTATATCAGATACTTG Gene: RS03038: Copper-containing nitrite reductase (EC 1.7.2.1)	* Ralstonia pickettii 12J Site: position = -241 score = 4.95742 sequence = GATGCATTAAGGATGCAAC Site: position = -191 score = 4.31863 sequence = GATGTATATCAGATGCTTG Gene: Rpic_4015: Copper-containing nitrite reductase (EC 1.7.2.1)	Copper-containing nitrite reductase (EC 1.7.2.1)
PF03781	Ralstonia eutropha H16	Cupriavidus taiwanensis	Ralstonia metallidurans CH34	Ralstonia eutropha JMP134	Ralstonia solanacearum GMI1000 Gene: RS03039: Probable signal peptide protein, PF03781	Ralstonia pickettii 12J Gene: Rpic_4016: Probable signal peptide protein, PF03781	Probable signal peptide protein, PF03781
PF02630	Ralstonia eutropha H16	Cupriavidus taiwanensis	Ralstonia metallidurans CH34	Ralstonia eutropha JMP134	Ralstonia solanacearum GMI1000 Gene: RS03040: electron transport protein SCO1/SenC	Ralstonia pickettii 12J Gene: Rpic_4017: electron transport protein SCO1/SenC	electron transport protein SCO1/SenC

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