Regulog Cobalamin - Corynebacteriaceae

Properties
Regulator type:	RNA regulatory element
Name:	Cobalamin
RFAM:	RF00174
Regulation mode:
Biological process:	Cobalamin biosynthesis
Effector:	Adenosylcobalamin
Phylum:	Actinobacteria

Member of regulog collections

By taxonomy - Corynebacteriaceae
By RNA motif - Cobalamin
By effector - Adenosylcobalamin
By pathway - Cobalamin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Corynebacterium glutamicum ATCC 13032	5	1
Corynebacterium efficiens YS-314
Corynebacterium diphtheriae NCTC 13129	3	1
Corynebacterium aurimucosum ATCC 700975
Corynebacterium jeikeium K411
Corynebacterium urealyticum DSM 7109
Corynebacterium amycolatum SK46	5	2
Corynebacterium kroppenstedtii DSM 44385	4	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
metE	Corynebacterium glutamicum ATCC 13032 Gene: cg1290: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Corynebacterium efficiens YS-314 Gene: CE1209: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Corynebacterium diphtheriae NCTC 13129	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411 Gene: jk0234: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Corynebacterium urealyticum DSM 7109 Gene: cur_1766: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Corynebacterium amycolatum SK46 Site: position = -218 score = 34.97 sequence = GTGTGTTTTGAGCTT... Gene: CORAM0001_1322: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Corynebacterium kroppenstedtii DSM 44385 Site: position = -344 score = 55.43 sequence = CGATAAGTAATGCGA... Gene: ckrop_1726: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

CRON 2.
btuF	Corynebacterium glutamicum ATCC 13032	Corynebacterium efficiens YS-314	Corynebacterium diphtheriae NCTC 13129 Gene: DIP1086: Vitamin B12 ABC transporter, B12-binding component BtuF	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109 Gene: cur_1342: Vitamin B12 ABC transporter, B12-binding component BtuF	Corynebacterium amycolatum SK46 Gene: CORAM0001_0685: Vitamin B12 ABC transporter, B12-binding component BtuF	2 Corynebacterium kroppenstedtii DSM 44385* Site: position = -136 score = 36.17 sequence = GGAATGCAGTGCGAA... Gene: ckrop_0414: Vitamin B12 ABC transporter, B12-binding component BtuF Gene: ckrop_1967: Vitamin B12 ABC transporter, B12-binding component BtuF	Vitamin B12 ABC transporter, B12-binding component BtuF
btuC	Corynebacterium glutamicum ATCC 13032	Corynebacterium efficiens YS-314	* Corynebacterium diphtheriae NCTC 13129 Site: position = -252 score = 84.29 sequence = GTGTTACACATTGAT... Gene: DIP1084: Vitamin B12 ABC transporter, permease component BtuC	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	Corynebacterium amycolatum SK46 Gene: CORAM0001_0683: Vitamin B12 ABC transporter, permease component BtuC	2 Corynebacterium kroppenstedtii DSM 44385 Gene: ckrop_0415: Vitamin B12 ABC transporter, permease component BtuC Gene: ckrop_1965: Vitamin B12 ABC transporter, permease component BtuC	Vitamin B12 ABC transporter, permease component BtuC
btuD	Corynebacterium glutamicum ATCC 13032	Corynebacterium efficiens YS-314	Corynebacterium diphtheriae NCTC 13129 Gene: DIP1085: Vitamin B12 ABC transporter, ATPase component BtuD / Adenosylcobinamide amidohydrolase (EC 3.5.1.90)	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	Corynebacterium amycolatum SK46 Gene: CORAM0001_0684: Vitamin B12 ABC transporter, ATPase component BtuD / Adenosylcobinamide amidohydrolase (EC 3.5.1.90)	2 Corynebacterium kroppenstedtii DSM 44385 Gene: ckrop_0416: Vitamin B12 ABC transporter, ATPase component BtuD / Adenosylcobinamide amidohydrolase (EC 3.5.1.90) Gene: ckrop_1966: Vitamin B12 ABC transporter, ATPase component BtuD / Adenosylcobinamide amidohydrolase (EC 3.5.1.90)	Vitamin B12 ABC transporter, ATPase component BtuD / Adenosylcobinamide amidohydrolase (EC 3.5.1.90)

CRON 3.
cg0625	* Corynebacterium glutamicum ATCC 13032 Site: position = -217 score = 25.7 sequence = CAGGGGAATTTCGGT... Gene: cg0625: Hypothetical protein	Corynebacterium efficiens YS-314 Gene: CE0547: Hypothetical protein	Corynebacterium diphtheriae NCTC 13129	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	Corynebacterium amycolatum SK46	Corynebacterium kroppenstedtii DSM 44385	Hypothetical protein
cg0624	Corynebacterium glutamicum ATCC 13032 Gene: cg0624: Hypothetical protein	Corynebacterium efficiens YS-314 Gene: CE0546: Hypothetical protein	Corynebacterium diphtheriae NCTC 13129	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	Corynebacterium amycolatum SK46	Corynebacterium kroppenstedtii DSM 44385	Hypothetical protein
cbrV	Corynebacterium glutamicum ATCC 13032 Gene: cg0623: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Corynebacterium efficiens YS-314 Gene: CE0545: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Corynebacterium diphtheriae NCTC 13129	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	Corynebacterium amycolatum SK46	Corynebacterium kroppenstedtii DSM 44385	Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter
cbrU	Corynebacterium glutamicum ATCC 13032 Gene: cg0622: Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter	Corynebacterium efficiens YS-314 Gene: CE0544: Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter	Corynebacterium diphtheriae NCTC 13129	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	Corynebacterium amycolatum SK46	Corynebacterium kroppenstedtii DSM 44385	Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter
cbrT	Corynebacterium glutamicum ATCC 13032 Gene: cg0621: Substrate-specific component CbrT of predicted cobalamin ECF transporter	Corynebacterium efficiens YS-314 Gene: CE0543: Substrate-specific component CbrT of predicted cobalamin ECF transporter	Corynebacterium diphtheriae NCTC 13129	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	Corynebacterium amycolatum SK46	Corynebacterium kroppenstedtii DSM 44385	Substrate-specific component CbrT of predicted cobalamin ECF transporter

CRON 4.
cbiM	Corynebacterium glutamicum ATCC 13032	Corynebacterium efficiens YS-314	Corynebacterium diphtheriae NCTC 13129	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	* Corynebacterium amycolatum SK46 Site: position = -325 score = 43.86 sequence = ATTCTGAGACGTGAT... Gene: CORAM0001_2224: Substrate-specific component CbiM of cobalt ECF transporter	Corynebacterium kroppenstedtii DSM 44385	Substrate-specific component CbiM of cobalt ECF transporter
cbiN	Corynebacterium glutamicum ATCC 13032	Corynebacterium efficiens YS-314	Corynebacterium diphtheriae NCTC 13129	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	Corynebacterium amycolatum SK46 Gene: CORAM0001_2223: Additional substrate-specific component CbiN of cobalt ECF transporter	Corynebacterium kroppenstedtii DSM 44385	Additional substrate-specific component CbiN of cobalt ECF transporter
cbiQ	Corynebacterium glutamicum ATCC 13032	Corynebacterium efficiens YS-314	Corynebacterium diphtheriae NCTC 13129	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	Corynebacterium amycolatum SK46 Gene: CORAM0001_2222: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Corynebacterium kroppenstedtii DSM 44385	Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cbiO	Corynebacterium glutamicum ATCC 13032	Corynebacterium efficiens YS-314	Corynebacterium diphtheriae NCTC 13129	Corynebacterium aurimucosum ATCC 700975	Corynebacterium jeikeium K411	Corynebacterium urealyticum DSM 7109	Corynebacterium amycolatum SK46 Gene: CORAM0001_2221: ATPase component CbiO of energizing module of cobalt ECF transporter	Corynebacterium kroppenstedtii DSM 44385	ATPase component CbiO of energizing module of cobalt ECF transporter

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Cobalamin - Corynebacteriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --