Regulog NrdR - Bacillales

Properties
Regulator type:	Transcription factor
Regulator family:	NrdR
Regulation mode:	repressor
Biological process:	Deoxyribonucleotide biosynthesis
Effector:	Deoxyribonucleotides
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 27 sites [see more]

Member of regulog collections

By taxonomy - Bacillales
By trascription factor - NrdR
By TF family - NrdR
By effector - Deoxyribonucleotides
By pathway - Deoxyribonucleotide biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Bacillus subtilis subsp. subtilis str. 168	4	1
Bacillus amyloliquefaciens FZB42	4	1
Bacillus pumilus SAFR-032	4	1
Bacillus licheniformis DSM 13	4	1
Anoxybacillus flavithermus WK1	4	1
Geobacillus kaustophilus HTA426	3	2
Bacillus cereus ATCC 14579	3	1
Bacillus halodurans C-125	3	2
Bacillus clausii KSM-K16	4	1
Oceanobacillus iheyensis HTE831	3	1
Paenibacillus sp. JDR-2	4	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
nrdA	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	* Anoxybacillus flavithermus WK1 Site: position = -356 score = 5.09744 sequence = ATACAACATATTGTGA Site: position = -325 score = 4.7516 sequence = CAACTATATATTGAAA Gene: Aflv_0393: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Geobacillus kaustophilus HTA426 Site: position = -291 score = 5.31296 sequence = CTACTATATATTGTTT Site: position = -260 score = 4.16362 sequence = CAACTATATATCGTTG Gene: GK0911: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Bacillus cereus ATCC 14579	* Bacillus halodurans C-125 Site: position = -395 score = 5.67688 sequence = ATACAATATATAGAGT Site: position = -363 score = 4.95893 sequence = TTACAATATCTAGTGT Gene: BH0501: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Bacillus clausii KSM-K16	* Oceanobacillus iheyensis HTE831 Site: position = -342 score = 4.74807 sequence = ATACAAGATATAGAAA Site: position = -310 score = 5.91877 sequence = ATACTATATATTGTGT Gene: OB3089: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Paenibacillus sp. JDR-2	Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Aflv_0392	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1 Gene: Aflv_0392: Transposase	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Transposase
Aflv_0391	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1 Gene: Aflv_0391: Flavodoxin	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831 Gene: OB3088: Flavodoxin	Paenibacillus sp. JDR-2	Flavodoxin
nrdB	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1 Gene: Aflv_0390: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Geobacillus kaustophilus HTA426 Gene: GK0912: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH0502: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831 Gene: OB3087: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Paenibacillus sp. JDR-2	Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)

CRON 2.
nrdI	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -92 score = 5.49746 sequence = AATCTATATATTGTGT Site: position = -59 score = 5.93251 sequence = ATACTATATATAGTGT Gene: BSU17370: Ribonucleotide reduction protein NrdI	* Bacillus amyloliquefaciens FZB42 Site: position = -85 score = 4.82452 sequence = TCTCAATATGTTGTGT Site: position = -52 score = 5.93251 sequence = ATACTATATATAGTGT Gene: RBAM_017170: Ribonucleotide reduction protein NrdI	* Bacillus pumilus SAFR-032 Site: position = -86 score = 4.55191 sequence = CATCTATATGTTGTGT Site: position = -54 score = 5.61304 sequence = ATACTATATATAGTGA Gene: BPUM_1628: Ribonucleotide reduction protein NrdI	* Bacillus licheniformis DSM 13 Site: position = -97 score = 5.4166 sequence = GCACAATATATTGTGT Site: position = -65 score = 5.91877 sequence = ATACTATATATTGTGT Gene: BLi01965: Ribonucleotide reduction protein NrdI	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	* Bacillus cereus ATCC 14579 Site: position = -65 score = 5.35741 sequence = ATACAATATATAGAGA Site: position = -44 score = 4.23244 sequence = GAACAACATATAGAGA Gene: BC1353: Ribonucleotide reduction protein NrdI	Bacillus halodurans C-125	* Bacillus clausii KSM-K16 Site: position = -100 score = 5.09344 sequence = AATCAATATATTGATT Site: position = -69 score = 4.27 sequence = CTACCATATGTGGTAT Gene: ABC3107: Ribonucleotide reduction protein NrdI	Oceanobacillus iheyensis HTE831	* Paenibacillus sp. JDR-2 Site: position = -139 score = 4.55191 sequence = CAACTACATATTGAGT Gene: Pjdr2_4012: Ribonucleotide reduction protein NrdI	Ribonucleotide reduction protein NrdI
nrdE	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU17380: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_017180: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)	Bacillus pumilus SAFR-032 Gene: BPUM_1629: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)	Bacillus licheniformis DSM 13 Gene: BLi01966: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579 Gene: BC1354: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)	Bacillus halodurans C-125	Bacillus clausii KSM-K16 Gene: ABC3108: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_4011: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)	Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
nrdF	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU17390: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_017190: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)	Bacillus pumilus SAFR-032 Gene: BPUM_1630: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)	Bacillus licheniformis DSM 13 Gene: BLi01967: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579 Gene: BC1355: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)	Bacillus halodurans C-125	Bacillus clausii KSM-K16 Gene: ABC3109: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_4010: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)	Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
ymaB	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU17400: Putative enzyme involved in deoxyribonucleotide synthesis	Bacillus amyloliquefaciens FZB42 Gene: RBAM_017200: Putative enzyme involved in deoxyribonucleotide synthesis	Bacillus pumilus SAFR-032 Gene: BPUM_1631: Putative enzyme involved in deoxyribonucleotide synthesis	Bacillus licheniformis DSM 13 Gene: BLi01968: Putative enzyme involved in deoxyribonucleotide synthesis	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16 Gene: ABC3110: Putative enzyme involved in deoxyribonucleotide synthesis	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Putative enzyme involved in deoxyribonucleotide synthesis

CRON 3.
nrdZ	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	* Geobacillus kaustophilus HTA426 Site: position = -135 score = 5.45091 sequence = TAACAATATATAGTAT Site: position = -102 score = 5.77038 sequence = ATACTATATATTGTTT Gene: GK2419: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)	Bacillus cereus ATCC 14579	* Bacillus halodurans C-125 Site: position = -178 score = 5.52849 sequence = AATCAATATATAGTAT Site: position = -145 score = 5.70791 sequence = ATACTATATATTGAAT Gene: BH2810: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	* Paenibacillus sp. JDR-2 Site: position = -110 score = 3.84062 sequence = TACCGATATGTAGTAT Site: position = -78 score = 5.05634 sequence = ACACAATATATGGTGC Gene: Pjdr2_3990: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)	Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NrdR - Bacillales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --