Regulog FabR - Enterobacteriales

Properties
Regulator type:	Transcription factor
Regulator family:	TetR
Regulation mode:	repressor
Biological process:	Fatty acid biosynthesis
Effector:	Unsaturated acyl-ACP; Unsaturated acyl-CoA
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 40 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - FabR
By TF family - TetR
By effector - Unsaturated acyl-ACP
By effector - Unsaturated acyl-CoA
By pathway - Fatty acid biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Escherichia coli str. K-12 substr. MG1655	3	3
Salmonella typhimurium LT2	3	3
Citrobacter koseri ATCC BAA-895	3	3
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	3	3
Enterobacter sp. 638	3	3
Erwinia amylovora ATCC 49946	3	3
Yersinia pestis KIM	4	4
Serratia proteamaculans 568	4	4
Erwinia carotovora subsp. atroseptica SCRI1043	4	4
Edwardsiella tarda EIB202	4	4
Proteus mirabilis HI4320	3	3
Photorhabdus luminescens subsp. laumondii TTO1	3	3

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
fabB	* Escherichia coli str. K-12 substr. MG1655 Site: position = -65 score = 6.44001 sequence = GGCGTACAAGTGTACGCT Gene: b2323: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Salmonella typhimurium LT2 Site: position = -66 score = 6.44001 sequence = GGCGTACAAGTGTACGCT Gene: STM2378: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Citrobacter koseri ATCC BAA-895 Site: position = -65 score = 6.44001 sequence = GGCGTACAAGTGTACGCT Gene: CKO_00462: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -65 score = 6.44001 sequence = GGCGTACAAGTGTACGCT Gene: KPN_02713: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Enterobacter sp. 638 Site: position = -64 score = 6.57187 sequence = AGCGTACAAGTGTACGCT Gene: Ent638_2871: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Erwinia amylovora ATCC 49946 Site: position = -64 score = 6.30567 sequence = GGCGTACAACTGTAAGCT Gene: EAM_2336: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Yersinia pestis KIM Site: position = -67 score = 6.34989 sequence = GGCGTACAACTGTACGCT Gene: y1591: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Serratia proteamaculans 568 Site: position = -66 score = 6.01836 sequence = GGCGTACATCTGTACGCT Gene: Spro_3368: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -68 score = 6.22137 sequence = AGCTTACAACTGTACGCT Gene: ECA3063: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Edwardsiella tarda EIB202 Site: position = -92 score = 6.29904 sequence = GGCGTACAGGTGTACGCT Gene: ETAE_2421: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Proteus mirabilis HI4320 Site: position = -71 score = 6.57187 sequence = AGCGTACAAGTGTACGCT Gene: PMI1795: 3-oxoacyl-[acyl-carrier-protein] synthase I	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -78 score = 6.57187 sequence = AGCGTACAAGTGTACGCT Gene: plu3184: 3-oxoacyl-[acyl-carrier-protein] synthase I	3-oxoacyl-[acyl-carrier-protein] synthase I

CRON 2.
fabA	* Escherichia coli str. K-12 substr. MG1655 Site: position = -56 score = 6.27527 sequence = AGCGTACACGTGTTAGCT Gene: b0954: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Salmonella typhimurium LT2 Site: position = -56 score = 6.27527 sequence = AGCGTACACGTGTTAGCT Gene: STM1067: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Citrobacter koseri ATCC BAA-895 Site: position = -56 score = 6.27527 sequence = AGCGTACACGTGTTAGCT Gene: CKO_02114: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -57 score = 6.0149 sequence = AGCTTACACGTGTTAGCT Gene: KPN_00983: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Enterobacter sp. 638 Site: position = -56 score = 6.27527 sequence = AGCGTACACGTGTTAGCT Gene: Ent638_1466: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Erwinia amylovora ATCC 49946 Site: position = -57 score = 5.78694 sequence = TGCTTACAACTGTAAGCT Gene: EAM_1374: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Yersinia pestis KIM Site: position = -56 score = 6.34077 sequence = AGCGTACAGCTGTACGCT Gene: y2740: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Serratia proteamaculans 568 Site: position = -56 score = 6.472 sequence = AGCGTACACGTGTAAGCT Gene: Spro_1751: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -56 score = 6.4309 sequence = AGCGTACAGGTGTACGCT Gene: ECA1748: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Edwardsiella tarda EIB202 Site: position = -56 score = 6.18514 sequence = AGCGTACACCTGTTAGCT Gene: ETAE_1264: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Proteus mirabilis HI4320 Site: position = -56 score = 6.52766 sequence = AGCGTACAAGTGTAAGCT Gene: PMI0782: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -57 score = 6.12648 sequence = AGCGTACAAGTGTACTCT Gene: plu1772: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

CRON 3.
lcfH	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	* Yersinia pestis KIM Site: position = -84 score = 5.84751 sequence = AGTGAACACCTGTACGCT Gene: y3641: putative long-chain-fatty-acid--CoA ligase	* Serratia proteamaculans 568 Site: position = -82 score = 5.47329 sequence = AGTAAACACGTGTAAGCT Gene: Spro_0747: putative long-chain-fatty-acid--CoA ligase	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -60 score = 5.58387 sequence = AATGTACAGCTGTACGCT Gene: ECA3830: putative long-chain-fatty-acid--CoA ligase	* Edwardsiella tarda EIB202 Site: position = -82 score = 5.46993 sequence = AGTGCACAGCTGTACGCT Gene: ETAE_0624: putative long-chain-fatty-acid--CoA ligase	* Proteus mirabilis HI4320 Site: position = -92 score = 6.11962 sequence = AGCGAACAGGTGTAAGCT Gene: PMI2081: putative long-chain-fatty-acid--CoA ligase	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -114 score = 5.85443 sequence = AGCTAACACCTGTAAGCT Gene: plu3671: putative long-chain-fatty-acid--CoA ligase	putative long-chain-fatty-acid--CoA ligase

CRON 4.
hyIII	* Escherichia coli str. K-12 substr. MG1655 Site: position = -81 score = 5.12884 sequence = AGCTAACAGGTGTTCACT Gene: b2899: COG1272: Predicted membrane protein, hemolysin III homolog	* Salmonella typhimurium LT2 Site: position = -82 score = 4.93828 sequence = AGCTAACATGTGTTCACT Gene: STM3049: COG1272: Predicted membrane protein, hemolysin III homolog	* Citrobacter koseri ATCC BAA-895 Site: position = -80 score = 5.12884 sequence = AGCTAACAGGTGTTCACT Gene: CKO_04262: COG1272: Predicted membrane protein, hemolysin III homolog	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -80 score = 5.12884 sequence = AGCTAACAGGTGTTCACT Gene: KPN_03327: COG1272: Predicted membrane protein, hemolysin III homolog	* Enterobacter sp. 638 Site: position = -86 score = 5.12884 sequence = AGCTAACAGGTGTTCACT Gene: Ent638_3317: COG1272: Predicted membrane protein, hemolysin III homolog	* Erwinia amylovora ATCC 49946 Site: position = -108 score = 5.86611 sequence = AGCTTACAAGTGTACTCT Gene: EAM_2786: COG1272: Predicted membrane protein, hemolysin III homolog	* Yersinia pestis KIM Site: position = -121 score = 5.853 sequence = AGCGTACAGGTGTACACT Gene: y3285: COG1272: Predicted membrane protein, hemolysin III homolog	* Serratia proteamaculans 568 Site: position = -89 score = 5.93832 sequence = AGCGTACACGTGTACACT Gene: Spro_3900: COG1272: Predicted membrane protein, hemolysin III homolog	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -157 score = 5.67795 sequence = AGCTTACACGTGTACACT Gene: ECA0757: COG1272: Predicted membrane protein, hemolysin III homolog	* Edwardsiella tarda EIB202 Site: position = -139 score = 5.93832 sequence = AGCGTACACGTGTACACT Gene: ETAE_2937: COG1272: Predicted membrane protein, hemolysin III homolog	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	COG1272: Predicted membrane protein, hemolysin III homolog

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog FabR - Enterobacteriales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --