Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of KdgR regulog to Klebsiella pneumoniae 342

Reference regulog properties
Source regulog: KdgR - Enterobacteriales
Regulator type: Transcription factor
Regulator family: IclR
Regulation mode: repressor (activator)
Biological process: Pectin and polygalacturonate utlization
Effector: 2-keto-3-deoxygluconate
Phylum: Proteobacteria/gamma
Propagated regulon:
Target genome Klebsiella pneumoniae 342
Orthologous TF(s) KPK_1947
Regulated genes 15
Built upon 159 sites [see more]
Predicted regulatory interactions in Klebsiella pneumoniae 342
Locus tag Position Score Sequence
Position: -87
Score: 5.3
Sequence: TAATGGAACGATGTTTTAATA
Locus tag: KPK_0230
KPK_0230 -87 5.3 TAATGGAACGATGTTTTAATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgK
Ortholog function: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03876 -87 5.3 TAATGGAACGATGTTTTAATA
Position: -59
Score: 5.8
Sequence: AAATAAAATAACGTTTCATAA
Position: -38
Score: 5.6
Sequence: AAACGAAATGACATTTTATTT
Locus tag: KPK_0845
KPK_0845 -59 5.8 AAATAAAATAACGTTTCATAA
-38 5.6 AAACGAAATGACATTTTATTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgM
Ortholog function: Oligogalacturonate-specific porin protein KdgM
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03267 -58 5.8 AAATAAAATGATGTTTCATAA
-37 5.6 AAACGAAATGTCATTTTATTT
Enterobacter sp. 638 Ent638_3298 -54 4.9 AAATAAAATGCAGTTCCATAA
-33 5.4 AAACGAAATGACATTTTAATT
Position: -103
Score: 5.6
Sequence: TAATGAAACGATGTTTTGATA
Locus tag: KPK_0846
KPK_0846 -103 5.6 TAATGAAACGATGTTTTGATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ogl
Ortholog function: Oligogalacturonate lyase (EC 4.2.2.6)
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03266 -299 5.8 ATTTAAAACGATGTTTCATTT
-103 5.6 TAATGAAACAATGTTTTGATA
Enterobacter sp. 638 Ent638_3297 -105 5 CATTGAAACGTCGTTTTGATA
Position: -208
Score: 5.8
Sequence: AAATGAAACATCGTTTTAAAT
Locus tag: KPK_0848
KPK_0848 -208 5.8 AAATGAAACATCGTTTTAAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kduD
Ortholog function: 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)
Escherichia coli str. K-12 substr. MG1655 b2842 -130 6.3 AAATGAAACATTGTTTTATTT
-63 5.4 AAACGAAACAGTGTTTCACTA
Salmonella typhimurium LT2 STM3017 -123 6.2 AAATGAAACGTTGTTTTATTT
-58 5.3 AATCAAAACAGTGTTTTGATT
Citrobacter koseri ATCC BAA-895 CKO_04219 -119 6.2 AAATGAAACAACGTTTTATTT
-51 4.4 AAACGGAACGGTGTTTCGCCT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03265 -207 5.8 AAATGAAACATCGTTTTAAAT
-139 5.2 AAACGGAACTCTGTTTTATTT
Enterobacter sp. 638 Ent638_3295 -127 5.4 AACTGAAACAACGTTTTAAAT
-60 5 AATCGGAACATTGTTTCGTTA
Position: -287
Score: 5
Sequence: TTTTGAAACATCGTTTCGACT
Position: -210
Score: 5.6
Sequence: AATTAAAACGGTGTTTTATAA
Locus tag: KPK_0857
KPK_0857 -287 5 TTTTGAAACATCGTTTCGACT
-210 5.6 AATTAAAACGGTGTTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: togM
Ortholog function: oligogalacturonide ABC transporter, inner membrane permease
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03256 -288 5 TTTTGAAACATCGTTTCGACT
-211 5.6 AATTAAAACGGTGTTTTATAA
Enterobacter sp. 638 Ent638_3289 -226 5.1 AATTAAAACGCCGTTTTACAA
Yersinia pestis KIM y1884 -152 4.5 AATCAAAACAACGTTCCGACT
-76 5.2 GATTGAAACGATGTTTCTATT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA2403 -139 4.5 AATCAAAACAACGTTCCGACT
-61 5.3 AATCAAAACAGTGTTTCTATT
Position: -39
Score: 5.8
Sequence: AAATGAAACAATGTTTCACTT
Locus tag: KPK_0859
KPK_0859 -39 5.8 AAATGAAACAATGTTTCACTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgF
Ortholog function: Pectin degradation protein KdgF
Citrobacter koseri ATCC BAA-895 CKO_04218 -38 5.6 AGTTGAAACATTGTTTCAATA
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03255 -39 5.8 AAATGAAACAATGTTTCACTT
Enterobacter sp. 638 Ent638_3287 -38 5.5 AATTAAAACAATGTTTCACTA
Yersinia pestis KIM y1888 -155 6 AAATGAAATGATGTTTTATTA
Erwinia carotovora subsp. atroseptica SCRI1043 ECA2399 -174 6.1 AAATGAAATAATGTTTTATTT
Position: -100
Score: 5
Sequence: TTTTGAAACGCCTTTTTAATT
Locus tag: KPK_1565
KPK_1565 -100 5 TTTTGAAACGCCTTTTTAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: setC
Ortholog function: lactose/glucose efflux system
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02601 -102 5 TTTTGAAACGCCTTTTTAATT
Enterobacter sp. 638 Ent638_2764 -109 4.9 TTTTGAAATGCTATTTTGATT
Position: -97
Score: 5.2
Sequence: TATAAAAACAGTGTTTCAAAA
Locus tag: KPK_1884
KPK_1884 -97 5.2 TATAAAAACAGTGTTTCAAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: togT
Ortholog function: Oligogalacturonide transporter
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02398 -46 5.2 TATAAAAACAGTGTTTCAAAA
Yersinia pestis KIM y2961 -47 4.5 AAAGAAAACAGTTATTCATTA
-25 6.1 AAATGAAACATTGTTTTAATT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA0817 -60 4.5 TAAAGAAATGATAGTTCAATC
-38 5.5 AACTGAAATATTGTTTCATAT
Position: -222
Score: 4.6
Sequence: AAATGAACCTACCTTTTTATT
Position: -200
Score: 5.4
Sequence: AAAAGAAATGCTGTTTTATAA
Locus tag: KPK_1894
KPK_1894 -222 4.6 AAATGAACCTACCTTTTTATT
-200 5.4 AAAAGAAATGCTGTTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rhiT
Ortholog function: Rhamnogalacturonide transporter
Citrobacter koseri ATCC BAA-895 CKO_01081 -190 5.4 AATAGAAACGCTGTTTTATAA
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02390 -200 4.9 AAGAGAAATGCTGTTTTATAA
Enterobacter sp. 638 Ent638_2444 -189 5.6 AAAAGAAACGCTGTTTTATAA
Erwinia carotovora subsp. atroseptica SCRI1043 ECA3560 -167 4.7 AGTTAAAATGCCTTTTTATAA
Position: -161
Score: 5
Sequence: AAATGAAACGGTTTTTTGAAT
Locus tag: KPK_1947
KPK_1947 -161 5 AAATGAAACGGTTTTTTGAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgR
Ortholog function: 2-keto-3-deoxy-D-gluconate repressor, IclR family
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02343 -161 5 AAATGAAACGGTTTTTTGAAT
Position: -106
Score: 5.1
Sequence: AACAAAAATAGCGTTTCAATT
Locus tag: KPK_2157
KPK_2157 -106 5.1 AACAAAAATAGCGTTTCAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ppsR
Ortholog function: PEP synthetase regulatory protein
Escherichia coli str. K-12 substr. MG1655 b1703 -131 5.3 AAATGAAATGCTGTTTTCATA
Salmonella typhimurium LT2 STM1348 -131 4.9 AAATGAAACACACTTTTCATT
Citrobacter koseri ATCC BAA-895 CKO_01727 -107 5.5 TATAAAAATAGCGTTTCATTT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02161 -97 5.1 AACAAAAATAGCGTTTCAATT
Enterobacter sp. 638 Ent638_1744 -107 5.3 ATTAAAAACACCATTTCATTT
Serratia proteamaculans 568 Spro_2173 -134 5.2 ATTTGAAATAGTGTTTTACTT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA1852 -94 5.6 TAATGAAATGGCGTTTTAATA
Position: -104
Score: 5.8
Sequence: AATCAAAACACTGTTTCATTT
Locus tag: KPK_3201
KPK_3201 -104 5.8 AATCAAAACACTGTTTCATTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kduD2
Ortholog function: 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)
Citrobacter koseri ATCC BAA-895 CKO_01753 -99 5.9 TTATAAAACACTGTTTCATTT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_01240 -104 5.8 AATCAAAACATTGTTTCATTT
Enterobacter sp. 638 Ent638_1716 -94 5.6 TTTTAAAACATCATTTCATTT
Position: -33
Score: 5.8
Sequence: AAATGAAATGCTGTTTTATAT
Locus tag: KPK_5010
KPK_5010 -33 5.8 AAATGAAATGCTGTTTTATAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yjgK
Ortholog function: cytoplasmic protein involved in polygalacturonate utilization
Escherichia coli str. K-12 substr. MG1655 b4252 -35 6 AAATGAAACGTTGTTTTAATT
Salmonella typhimurium LT2 STM4468 -32 5.7 AAATAAAACGCTGTTTTAACT
Citrobacter koseri ATCC BAA-895 CKO_03553 -33 6.2 AAATGAAACGTTGTTTTATTT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_04658 -33 5.8 AAATGAAATGCTGTTTTATAT
Enterobacter sp. 638 Ent638_0453 -34 6 AAATGAAACATTGTTTTATAT
Yersinia pestis KIM y0739 -41 5.9 TAATAAAACAGCATTTCATTT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA0383 -41 5.1 TTGTAAAACAGGGTTTCATTT
Edwardsiella tarda EIB202 ETAE_3112 -39 5.6 AAATAAAACGCAGTTTTATAA
Position: -114
Score: 5
Sequence: AACAGAAATGACGTTTCATCA
Locus tag: KPK_5209
KPK_5209 -114 5 AACAGAAATGACGTTTCATCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: yjcB
Ortholog function: putative inner membrane protein
Salmonella typhimurium LT2 STM4263 -120 5.4 AATAGAAACAATGTTTCATTC
Citrobacter koseri ATCC BAA-895 CKO_03830 -121 5.1 AACAGAAACGTTGTTTCATTC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_04460 -113 4.9 AACAGAAATGGCGTTTCATCA