Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of BirA regulog to Bacillus pseudofirmus OF4

Reference regulog properties
Source regulog: BirA - Bacillales
Regulator type: Transcription factor
Regulator family: BirA
Regulation mode: repressor
Biological process: Biotin biosynthesis
Effector: Biotin
Phylum: Firmicutes
Propagated regulon:
Target genome Bacillus pseudofirmus OF4
Orthologous TF(s) BpOF4_15590
Regulated genes 4
Built upon 36 sites [see more]
Predicted regulatory interactions in Bacillus pseudofirmus OF4
Locus tag Position Score Sequence
Position: -49
Score: 8.7
Sequence: ATGTTAAC-(15)-GTTAACAT
Locus tag: BpOF4_01215
BpOF4_01215 -49 8.7 ATGTTAAC-(15)-GTTAACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: bioB
Ortholog function: Biotin synthase (EC 2.8.1.6)
Bacillus subtilis subsp. subtilis str. 168 BSU30200 -85 8.8 TTGTTAAC-(15)-GTTAACAA
Bacillus amyloliquefaciens FZB42 RBAM_018250 -126 7.2 CAGTTAAC-(15)-GTTGACAT
-64 8.2 GTGTTAAC-(15)-GTTAACAT
Bacillus pumilus SAFR-032 BPUM_2779 -48 8.7 ATGTTAAC-(15)-GTTAACAT
Bacillus licheniformis DSM 13 BLi00770 -55 8.7 ATGTTAAC-(15)-GTTAACAT
Anoxybacillus flavithermus WK1 Aflv_1376 -55 8.7 TTGTTAAC-(15)-GTTGACAT
Geobacillus kaustophilus HTA426 GK1570 -86 7.8 AAGTAAAC-(15)-GTTGACAA
Bacillus cereus ATCC 14579 BC4114 -45 8.7 ATGTTAAC-(15)-GTTAACAT
Bacillus halodurans C-125 BH1748 -56 8.7 TTGTTAAC-(15)-GTTTACAA
Paenibacillus sp. JDR-2 Pjdr2_1463 40 8.8 TTGTTAAC-(18)-GTTAACAA
Position: -107
Score: 8.8
Sequence: TTGTTAAC-(15)-GTTAACAA
Locus tag: BpOF4_04200
BpOF4_04200 -107 8.8 TTGTTAAC-(15)-GTTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: bioD
Ortholog function: Dethiobiotin synthetase (EC 6.3.3.3)
Bacillus halodurans C-125 BH0783 -42 8.7 ATGTTAAC-(15)-GTTAACAT
Position: -86
Score: 8.7
Sequence: TTGTTAAC-(15)-GTTGACAA
Position: -32
Score: 7.8
Sequence: ATGTTAAC-(16)-GTGAACAT
Locus tag: BpOF4_04690
BpOF4_04690 -86 8.7 TTGTTAAC-(15)-GTTGACAA
-32 7.8 ATGTTAAC-(16)-GTGAACAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: bioY1
Ortholog function: Substrate-specific component BioY of biotin ECF transporter
Bacillus subtilis subsp. subtilis str. 168 BSU32030 -87 8.7 TTGTTAAC-(15)-GTTGACAA
Bacillus amyloliquefaciens FZB42 RBAM_029080 -84 7.9 TAGTAAAC-(15)-GTTGACAA
Bacillus pumilus SAFR-032 BPUM_2863 -83 8.7 TTGTTAAC-(15)-GTTGACAA
Bacillus licheniformis DSM 13 BLi03385 -89 8.7 TTGTTAAC-(15)-GTTGACAA
Anoxybacillus flavithermus WK1 Aflv_2398 -31 8.1 TCGTTAAC-(15)-GTTAACAA
Geobacillus kaustophilus HTA426 GK2944 -31 8.6 TTGTTAAC-(15)-GTTTACAT
Bacillus cereus ATCC 14579 BC4917 107 8.7 ATGTTAAC-(16)-GTTAACAT
Bacillus halodurans C-125 BH3358 -87 8.6 ATGTCAAC-(15)-GTTGACAA
-33 7.8 ATGTTAAC-(15)-GTAAACAT
Oceanobacillus iheyensis HTE831 OB2346 -81 8.6 TTGTCAAC-(15)-GTTGACAA
Position: -62
Score: 8.8
Sequence: TTGTTAAC-(15)-GTTAACAA
Locus tag: BpOF4_16065
BpOF4_16065 -62 8.8 TTGTTAAC-(15)-GTTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: bioW
Ortholog function: Pimeloyl-CoA synthase (EC 6.2.1.14)
Bacillus subtilis subsp. subtilis str. 168 BSU30240 -85 8.8 TTGTTAAC-(15)-GTTAACAA
Bacillus amyloliquefaciens FZB42 RBAM_018290 -126 7.2 CAGTTAAC-(15)-GTTGACAT
-64 8.2 GTGTTAAC-(15)-GTTAACAT
Bacillus licheniformis DSM 13 BLi00766 -55 8.7 ATGTTAAC-(15)-GTTAACAT