Propagation of MtaR regulog to Streptococcus mutans NN2025

Reference regulog properties
Source regulog:	MtaR - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	LysR
Regulation mode:	repressor
Biological process:	Methionine metabolism
Effector:	Homocysteine
Phylum:	Firmicutes
Propagated regulon:
Target genome	Streptococcus mutans NN2025
Orthologous TF(s)	SmuNN2025_0828
Regulated genes	8

Built upon 72 sites [see more]

Predicted regulatory interactions in *Streptococcus mutans NN2025*
	Locus tag	Position	Score	Sequence
Position: -100 Score: 6.1 Sequence: TATAGTTTTTAGCTATA Locus tag: SmuNN2025_0211
	SmuNN2025_0211	-100	6.1	TATAGTTTTTAGCTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metQ
Ortholog function: Methionine ABC transporter, substrate-binding protein
Streptococcus mutans UA159	SMU.1941	-100	6.1	TATAGTTTTTAGCTATA

Position: -110 Score: 5.4 Sequence: TATAGGTAATAACTATA Locus tag: SmuNN2025_0216
	SmuNN2025_0216	-110	5.4	TATAGGTAATAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: COG1912
Ortholog function: Conserved hypothetical protein
Streptococcus gordonii str. Challis substr. CH1	SGO_0468	-30	4.5	TAAAGTTCAGGACTATA
Streptococcus mitis B6	smi_1812	-91	4.6	TATAAGGTAAAACTATA
Streptococcus mutans UA159	SMU.1936c	-110	5.4	TATAGGTAATAACTATA
Streptococcus pneumoniae TIGR4	SP_0481	-64	4.6	TATAAGGTAAAACTATA
Streptococcus thermophilus CNRZ1066	str0304	-100	4.5	CATAGCCAAAGGCTATA
Streptococcus uberis 0140J	SUB0314	-106	6.3	TATAGTTTTAGACTATA

Position: -100 Score: 6.5 Sequence: TATAGTTTAAAACTATA Locus tag: SmuNN2025_0623
	SmuNN2025_0623	-100	6.5	TATAGTTTAAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE2
Ortholog function: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
Streptococcus mutans UA159	SMU.1487	-100	6.5	TATAGTTTAAAACTATA
Streptococcus sanguinis SK36	SSA_0917	-83	5.2	AATAGTTTTCGGCTATA
Streptococcus thermophilus CNRZ1066	str0905	-257	5.9	TATAGTCTAAAACTATA

Position: -102 Score: 5.3 Sequence: TATAGTTGGAACCTATA Position: -68 Score: 5.2 Sequence: TATATTTGATAACTATA Locus tag: SmuNN2025_0642
	SmuNN2025_0642	-102	5.3	TATAGTTGGAACCTATA
		-68	5.2	TATATTTGATAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metA
Ortholog function: Homoserine O-succinyltransferase (EC 2.3.1.46)
Streptococcus gallolyticus UCN34	GALLO_0824	-105	5.9	TATAGCTAAAAACTATA
		-71	5.4	TATAATTGAAAACTATA
Streptococcus gordonii str. Challis substr. CH1	SGO_1002	-97	5.6	CATAGTTTCAGGCTATA
		-63	5.4	TATAATTGAAAACTATA
Streptococcus mutans UA159	SMU.1466	-102	5.3	TATAGTTGGAACCTATA
		-68	5.2	TATATTTGATAACTATA
Streptococcus pneumoniae TIGR4	SP_1576	-109	5.4	TATAATTGAAAACTATA
Streptococcus sanguinis SK36	SSA_1420	-145	5.8	CATAGTTTCTAACTATA
		-111	5.4	TATAATTGAAAACTATA
Streptococcus thermophilus CNRZ1066	str1222	-103	5.6	TATAGTTTAAAGTTATA

Position: -99 Score: 6.3 Sequence: TATAGTTTATAACTATA Locus tag: SmuNN2025_0871
	SmuNN2025_0871	-99	6.3	TATAGTTTATAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metY
Ortholog function: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)
Streptococcus mutans UA159	SMU.1173	-66	6.3	TATAGTTTATAACTATA

Position: -186 Score: 5.6 Sequence: TATAGATGAAAACTATA Position: -155 Score: 6.1 Sequence: TATAGCTTAAAACTATA Locus tag: SmuNN2025_1143
	SmuNN2025_1143	-186	5.6	TATAGATGAAAACTATA
		-155	6.1	TATAGCTTAAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Streptococcus agalactiae 2603V/R	SAG2049	-132	6.5	TATAGTTTAAAACTATA
Streptococcus gallolyticus UCN34	GALLO_1316	-170	6.3	TATAGTTAAAAACTATA
		-139	5.9	TATAGCTAAAAACTATA
		-36	5.2	TATAGTTTAAAACTAAT
Streptococcus gordonii str. Challis substr. CH1	SGO_0310	-180	5.4	TATAGTTTTTGATTATA
		-97	5.9	TATAGTTTTTGGCTATA
Streptococcus mitis B6	smi_1600	-99	6.4	TATAGTTTCAAACTATA
Streptococcus mutans UA159	SMU.873	-186	5.6	TATAGATGAAAACTATA
		-155	6.1	TATAGCTTAAAACTATA
Streptococcus pneumoniae TIGR4	SP_0585	-99	6.4	TATAGTTTCAAACTATA
Streptococcus sanguinis SK36	SSA_0416	-180	4.8	CATAATTTCTACCTATA
		-97	6.3	TATAGTTTTAGACTATA
Streptococcus suis 05ZYH33	SSU05_1774	-235	5.2	CATAGATAAAATCTATA
		-99	4.8	TATAGTCAAAAGTTATA
Streptococcus thermophilus CNRZ1066	str0785	-130	5.9	TATAGTTATTAGCTATA
		-58	6.5	TATAGTTTAAAACTATA

Position: -94 Score: 4.6 Sequence: TATAATATTTAAATATA Locus tag: SmuNN2025_1403
	SmuNN2025_1403	-94	4.6	TATAATATTTAAATATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: folD
Ortholog function: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Streptococcus mitis B6	smi_0869	-35	6.2	TATAGTTTGAAACTATA
Streptococcus mutans UA159	SMU.572	-93	4.6	TATAATATTTAAATATA
Streptococcus pneumoniae TIGR4	SP_0825	-98	6.3	TATAGTTTAAAGCTATA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of MtaR regulog to Streptococcus mutans NN2025

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --