Propagation of CcpA regulog to Streptococcus pyogenes M49 591

Reference regulog properties
Source regulog:	CcpA - Streptococcaceae
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:
Biological process:	Global catabolite repression
Effector:	Fructose-1,6-bisphosphate; HPr, phosphocarrier protein
Phylum:	Firmicutes
Propagated regulon:
Target genome	Streptococcus pyogenes M49 591
Orthologous TF(s)	No orthologous TFs found
Regulated genes	37

Built upon 968 sites [see more]

Predicted regulatory interactions in *Streptococcus pyogenes M49 591*
	Locus tag	Position	Score	Sequence
Position: -16 Score: 4.1 Sequence: ATGAAAGGGATTTTTT Locus tag: SpyoM01000056
	SpyoM01000056	-16	4.1	ATGAAAGGGATTTTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: rnc
Ortholog function: Ribonuclease III (EC 3.1.26.3)
Streptococcus agalactiae 2603V/R	SAG0723	-94	4.6	AAGGAAACGTTTTCTT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0572	-16	4.1	ATGAAAGGGGTTTTTT
Streptococcus gallolyticus UCN34	GALLO_1551	-90	4	GAAAAAGCGTTTTAAT
		-56	4.1	AAAGAAACGTTTTAAT
Streptococcus pyogenes M1 GAS	SPy0531	-16	4.1	ATGAAAGGGATTTTTT
Streptococcus suis 05ZYH33	SSU05_1192	-142	4.2	ATGTAAATGTTTGCAA
Streptococcus suis 05ZYH33	SSU05_1191	-142	4.2	ATGTAAATGTTTGCAA

Position: -116 Score: 4.9 Sequence: TTTAAATCGCTTTCAT Locus tag: SpyoM01000089
	SpyoM01000089	-116	4.9	TTTAAATCGCTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yhcR
Ortholog function: 5'-nucleotidase (EC 3.1.3.5)
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0825	-116	4.9	TTTAAAGCGATTTCAT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1088	-135	4.6	TTTTAAACGTTTTCAG
Streptococcus pyogenes M1 GAS	SPy0872	-116	4.9	TTTAAATCGCTTTCAT

Position: -37 Score: 4.5 Sequence: ATGTAAGCGTTTCAAT Locus tag: SpyoM01000145
	SpyoM01000145	-37	4.5	ATGTAAGCGTTTCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: atoB
Ortholog function: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1437	-80	4.2	TTGCAAACGCTTTTAG
		-39	5.1	TAGAAAGCGCTTTCTA
Streptococcus pyogenes M1 GAS	SPy0140	-37	4.5	ATGTAAGCGTTTCAAT

Position: -190 Score: 4.9 Sequence: ATGAAAACGTTGTCAT Locus tag: SpyoM01000147
	SpyoM01000147	-190	4.9	ATGAAAACGTTGTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: atoE
Ortholog function: Short chain fatty acids transporter
Streptococcus pyogenes M1 GAS	SPy0137	-190	4.9	ATGAAAACGCTGTCAT

Position: -28 Score: 4.6 Sequence: CAGAAAACGATTTCAA Locus tag: SpyoM01000162
	SpyoM01000162	-28	4.6	CAGAAAACGATTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ackA
Ortholog function: Acetate kinase (EC 2.7.2.1)
Lactococcus lactis subsp. cremoris SK11	LACR_2294	-30	4.3	AATAAAACGCATACAT
Lactococcus lactis subsp. cremoris SK11	LACR_2295	-129	4.4	ATGCAAACGCTTTTTA
Lactococcus lactis subsp. lactis Il1403	L0224	-30	4.3	AATAAAACGCATACAT
Lactococcus lactis subsp. lactis Il1403	L73818	-129	4.5	TTGAAAAGGTTTTTAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0142	-28	4.9	TAGAAAACGATTTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0124	-28	4.6	CAGAAAACGATTTCAA
Streptococcus gallolyticus UCN34	GALLO_0095	-25	4.4	ATGAAAGCGCTTTAGA
Streptococcus gordonii str. Challis substr. CH1	SGO_1916	-26	4.6	CTGAAAACGCTTAAAA
Streptococcus mitis B6	smi_0214	-90	5	ATGAAAACGCTTAAAA
Streptococcus mutans UA159	SMU.1978	-28	4.3	TCGTAAACGATTTCAT
Streptococcus pneumoniae TIGR4	SP_2044	-30	4.9	TTGAAAACGCTTAAAA
Streptococcus pyogenes M1 GAS	SPy0109	-28	4.6	CAGAAAACGATTTCAA
Streptococcus sanguinis SK36	SSA_0192	-26	4.6	TTGAAAACGCTTAAAG
		3	4.3	TCGAAAACGATTTCTA
Streptococcus suis 05ZYH33	SSU05_0135	-27	4.5	AGGAAAACGCTTTAAA
Streptococcus thermophilus CNRZ1066	str1857	0	4.9	TTGAAAGCGTTTTATA
Streptococcus uberis 0140J	SUB0126	-28	4.6	CAGAAAACGATTTCAA

Position: -90 Score: 4.3 Sequence: CTGAAAACATTTACAA Locus tag: SpyoM01000242
	SpyoM01000242	-90	4.3	CTGAAAACATTTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: typA
Ortholog function: GTP-binding protein TypA/BipA
Lactococcus lactis subsp. cremoris SK11	LACR_2298	-167	3.8	TATTTAGCGATTTTAT
		-71	4	TTGTAAACGTGTGCAT
Streptococcus agalactiae 2603V/R	SAG0473	-96	4	ATGAAAACATTTACAC
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1513	-90	4.3	CTGAAAACATTTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0589	-75	4.6	TTGAAAACATTTACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_0669	-97	4	ATGAAAACATTTACAC
Streptococcus mutans UA159	SMU.546	-95	4.3	TTTAAAACATTTACAT
Streptococcus sanguinis SK36	SSA_0650	33	4	ATGAAAACATTTACAC
Streptococcus suis 05ZYH33	SSU05_0468	-89	4.3	CTGAAAACATTTACAA
Streptococcus thermophilus CNRZ1066	str0729	-89	4.3	TGAAAAACGTTTACAA
Streptococcus uberis 0140J	SUB1296	-94	4.3	CTGAAAACATTTACAA

Position: -60 Score: 4.5 Sequence: TAGAAAGCGATTCCAT Locus tag: SpyoM01000245
	SpyoM01000245	-60	4.5	TAGAAAGCGATTCCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yvaA
Ortholog function: Bacterial conserved protein of unknown function (DUF910) family
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1516	-42	4.5	TAGAAAGCGATTCCAT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0586	-60	4.2	CAGAAAGCGATTGCAT
Streptococcus mutans UA159	SMU.541	-58	3.9	AGGCAAGCGCTTGCAA
Streptococcus pyogenes M1 GAS	SPy1530	-60	4.5	TAGAAAGCGATTCCAT
Streptococcus thermophilus CNRZ1066	str0727	-58	4	CTATAAAGGTTTTCAA

Position: -68 Score: 4.1 Sequence: TTGGAAGCGTTTTTTG Locus tag: SpyoM01000340
	SpyoM01000340	-68	4.1	TTGGAAGCGTTTTTTG
Supported by regulated orthologs from reference regulons
Ortholog gene name: naoX
Ortholog function: Predicted NADH oxidase
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0909	-68	4.1	TTGGAAGCGTTTTTTG
Streptococcus gallolyticus UCN34	GALLO_1130	-66	4.8	TTGTAAGCGTTTTATA
Streptococcus gordonii str. Challis substr. CH1	SGO_1167	-67	4.3	TTGAAACCGCTAACAG
Streptococcus mitis B6	smi_1390	-67	4.4	TTGTAAACGCTAACAG
Streptococcus pyogenes M1 GAS	SPy1150	-68	4.1	TTGGAAGCGTTTTTTG
Streptococcus sanguinis SK36	SSA_1127	-66	4.2	TTGTAAACGCTCACAG
Streptococcus suis 05ZYH33	SSU05_0730	-59	4.3	TTGAAATCGGTAACAT
Streptococcus thermophilus CNRZ1066	str1281	-57	4.2	GTGTAACCGTTTTCTA
Streptococcus uberis 0140J	SUB0877	-72	4.5	TTGGAAGCGTTTTATT

Position: -35 Score: 4 Sequence: AAGTAAGCGCTTCAAG Locus tag: SpyoM01000362
	SpyoM01000362	-35	4	AAGTAAGCGCTTCAAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: raiA
Ortholog function: Ribosome-associated protein Y
Lactococcus lactis subsp. cremoris SK11	LACR_0667	-133	4.4	ATGAAAGCTGTTTCAT
Lactococcus lactis subsp. lactis Il1403	L32389	-133	4.4	ATGAAAGCTGTTTCAT
Streptococcus agalactiae 2603V/R	SAG0338	-60	4.6	ATGAAAGCGGTTATAA
		-36	4.7	TAGAAAGCGTTAACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1681	-64	4.5	ATGAAAGCGGTATAAT
		-35	4.2	AAGAAAGCGCTTCAAG
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1545	-36	4.9	AAGAAAGCGTTTTAAA
Streptococcus gallolyticus UCN34	GALLO_0504	-59	3.8	ATGAAAGCAGTATAAT
		-34	4.8	AAGAAAGCGCTTTATA
Streptococcus gordonii str. Challis substr. CH1	SGO_0610	-63	4.7	ATGAAAGCGTTATAAT
Streptococcus mitis B6	smi_2056	-57	4.7	ATGAAAGCGTTATAAT
Streptococcus mutans UA159	SMU.500	-58	4.5	ATGAAAGCGATATAAT
Streptococcus pneumoniae TIGR4	SP_2206	-57	4.7	ATGAAAGCGTTATAAT
Streptococcus pyogenes M1 GAS	SPy1613	-64	3.8	ATGAAAGCAGTATAAT
		-35	4	AAGTAAGCGCTTCAAG
Streptococcus sanguinis SK36	SSA_1834	-60	4.7	ATGAAAGCGTTATAAT
Streptococcus suis 05ZYH33	SSU05_0439	-42	4.5	AAGAAAACGGTTGCAA
Streptococcus thermophilus CNRZ1066	str0370	-57	3.9	ATGAAAAGGATATAAT
		-34	4.7	AAGAAAACGCTAACAA
Streptococcus uberis 0140J	SUB1375	-59	4.4	ATGAAAACGGTATAAT

Position: -65 Score: 4.2 Sequence: AATAAAACGTTTACCA Position: 0 Score: 4.2 Sequence: ATGAAAACGTTAAGAA Locus tag: SpyoM01000382
	SpyoM01000382	-65	4.2	AATAAAACGTTTACCA
		0	4.2	ATGAAAACGTTAAGAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: SPy1879
Ortholog function: Predicted membrane protein
Streptococcus agalactiae 2603V/R	SAG1765	-65	4.8	AATAAAACGTTTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1933	-110	3.9	AGGAAAACGTCTTCTT
Streptococcus gallolyticus UCN34	GALLO_1994	-157	4.1	AAGAAAACATTTTATT
		-86	4.2	TGGTAAACGCATTCAT
Streptococcus pyogenes M1 GAS	SPy1879	-65	4.2	AATAAAACGTTTACCA

Position: -224 Score: 4.3 Sequence: TTTTTAACGTTTTCTA Position: -81 Score: 4.4 Sequence: TTGAAAGCGCTCTATT Locus tag: SpyoM01000432
	SpyoM01000432	-224	4.3	TTTTTAACGTTTTCTA
		-81	4.4	TTGAAAGCGCTCTATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nanE
Ortholog function: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Streptococcus agalactiae 2603V/R	SAG0033	-74	5.1	TTGAAAACGCTTTAAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0245	-142	4.6	CTGAATACGTTTTCAA
		-72	5.1	TTGAAAACGCTTTAAT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0241	-72	4.5	TTGAAAGTGTTTTAAT
Streptococcus gordonii str. Challis substr. CH1	SGO_0118	-76	5.1	TTGAAAGCGCTTTAAT
Streptococcus mitis B6	smi_0602	-63	4.5	TTGAAAGCGCTTCATA
Streptococcus pneumoniae TIGR4	SP_1685	-63	5.1	TTGAAAGCGTTTTAAT
Streptococcus sanguinis SK36	SSA_0071	-181	5.1	TTGAAAGCGCTTTAAA
Streptococcus suis 05ZYH33	SSU05_1402	-43	4.1	ATGTAAGCGCTATCTC
Streptococcus uberis 0140J	SUB1658	-76	4.9	TTGAAAACGCTTTATT

Position: -75 Score: 5.1 Sequence: TTTAAAACGCTTTCAT Locus tag: SpyoM01000685
	SpyoM01000685	-75	5.1	TTTAAAACGCTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: sgaT
Ortholog function: Ascorbate-specific PTS system, IIC component
Streptococcus agalactiae 2603V/R	SAG1815	-71	4.9	TTTAAAACGCTTACAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_2013	-171	4	TTTAAAGAGTTTTAAA
		-75	5.1	TTTAAAACGCTTTCAT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0168	-76	5	TTTAAAACGCTTACAT
Streptococcus gallolyticus UCN34	GALLO_2127	-71	4.3	TTGTTTGCGCTTACAT
Streptococcus mitis B6	smi_0219	-60	4.4	TTGTTTACGCTTTCAA
Streptococcus mutans UA159	SMU.270	-72	4.2	TTGTTAGCATTTTCAA
Streptococcus pyogenes M1 GAS	SPy0174	-81	5.1	TTTAAAACGCTTTCAT
Streptococcus sanguinis SK36	SSA_2093	-70	4.6	TTGTTATCGCTTTCAA
Streptococcus suis 05ZYH33	SSU05_2063	-64	4	TTGTTTCCGCTTACAT
Streptococcus uberis 0140J	SUB1727	-76	4.5	TTTAAAACGCTTTCAC

Position: -59 Score: 4.9 Sequence: TTGAAATCGATTTCAT Locus tag: SpyoM01000757
	SpyoM01000757	-59	4.9	TTGAAATCGATTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: gabD
Ortholog function: Succinate-semialdehyde dehydrogenase [NAD] (EC 1.2.1.24); Succinate-semialdehyde dehydrogenase [NADP+] (EC 1.2.1.16)
Streptococcus agalactiae 2603V/R	SAG1124	-53	4.8	TTGTAATCGATTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1202	-56	4.9	TTGAAATCGATTTCAA
Streptococcus gallolyticus UCN34	GALLO_0925	-146	4.1	ACGATAGCGTTTACTT
		-132	4.1	TTGAAACCGTTTCCTG
Streptococcus mutans UA159	SMU.2127	-57	4.8	TTGAAATCGGTTTCAA
Streptococcus pyogenes M1 GAS	SPy1067	-59	4.9	TTGAAATCGATTTCAT
Streptococcus uberis 0140J	SUB1058	-56	4.3	TTGAAATCGTTACCAA

Position: -54 Score: 4.3 Sequence: TTGAAAGCGCTACAAT Locus tag: SpyoM01000831
	SpyoM01000831	-54	4.3	TTGAAAGCGCTACAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: hylD
Ortholog function: PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69)
Streptococcus agalactiae 2603V/R	SAG1902	-57	4.8	ATGAAAGCGCTATAAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0648	-54	4.3	TTGAAAGCGCTACAAT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1304	-54	4.3	TTGAAAGCGCTACAAT
Streptococcus pneumoniae TIGR4	SP_0321	-107	4.6	ATGAAAGCGCTAATAT
		-63	3.8	AAATAAAGGATTACAA
Streptococcus pyogenes M1 GAS	SPy0634	-54	4.3	TTGAAAGCGCTACAAT
Streptococcus suis 05ZYH33	SSU05_1221	-102	4.8	TATAAAACGCTTACAT

Position: 19 Score: 4.1 Sequence: AAATTAGCGCTTTAAT Locus tag: SpyoM01000836
	SpyoM01000836	19	4.1	AAATTAGCGCTTTAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: atpA
Ortholog function: ATP synthase alpha chain (EC 3.6.3.14)
Lactococcus lactis subsp. cremoris SK11	LACR_1935	-135	4.3	TATCAAACGCTTACAA
Streptococcus agalactiae 2603V/R	SAG0861	-93	4.5	ATGAAAACGTAATCAA
Streptococcus gordonii str. Challis substr. CH1	SGO_1544	-96	4.6	TTAAAATCGCTTACAA
Streptococcus mitis B6	smi_1311	-93	4.5	CATTAAACGCTTTCAA
Streptococcus mutans UA159	SMU.1530	-161	4.1	TTAAAAGCGTCTTCTA
Streptococcus pneumoniae TIGR4	SP_1510	-93	4.3	TATTAAACGCTTCCAA
Streptococcus sanguinis SK36	SSA_0786	-194	4.5	TTTTAATCGCTTTCTT
		-95	4.4	CAAAAAACGCTTACAA
Streptococcus suis 05ZYH33	SSU05_1174	-92	4.7	AATTAAACGCTTACAA
Streptococcus uberis 0140J	SUB0670	-94	4.4	AAGAAAGCGTAATCAA

Position: -90 Score: 4.9 Sequence: ATGTAAACGATTACAA Locus tag: SpyoM01000862
	SpyoM01000862	-90	4.9	ATGTAAACGATTACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: celX
Ortholog function: Cellobiose-specific PTS system, IIA component (EC 2.7.1.69)
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0172	-79	4.8	AAGAAAACGATTACAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1811	-85	4.9	ATGTAAACGATTACAA
Streptococcus gordonii str. Challis substr. CH1	SGO_1791	-64	5.1	ATAAAAGCGCTTTCAT
		-41	3.8	AAATAAACGTTGTTAA
Streptococcus pyogenes M1 GAS	SPy2052	-90	4.9	ATGTAAACGATTACAA
Streptococcus sanguinis SK36	SSA_0282	-66	4.1	AATAAATCACTTTCAA

Position: -69 Score: 4.4 Sequence: TTTTTAGCGTTTTCTT Position: -38 Score: 4.7 Sequence: TGGAAAGCGCTTTCTA Locus tag: SpyoM01000883
	SpyoM01000883	-69	4.4	TTTTTAGCGTTTTCTT
		-38	4.7	TGGAAAGCGCTTTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: atoB
Ortholog function: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) / Acetyl-CoA acetyltransferase (EC 2.3.1.9)
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1700	-69	4.2	TTTTGAGCGTTTTCTT
		-38	4.8	CAGAAAGCGCTTTCTA
Streptococcus pyogenes M1 GAS	SPy1637	-70	4.4	TTTTTAGCGTTTTCTT
		-39	3.9	TGGAAAGCGCTTTTCT
Streptococcus uberis 0140J	SUB1394	-40	5.1	AAGAAAGCGCTTTCTA

Position: 7 Score: 3.9 Sequence: TTAAACGCGTTTTAAA Locus tag: SpyoM01000895
	SpyoM01000895	7	3.9	TTAAACGCGTTTTAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: licT
Ortholog function: Beta-glucoside bgl operon transcriptional antiterminator, BglG family
Streptococcus agalactiae 2603V/R	SAG0789	-171	4	ATTAAGACGTTTTCAG
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0582	-173	4.2	ATTAAAGCGTTCTCAG
		7	3.9	TTAAACGCGTTTTAAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1377	-174	4.3	ATGAAAACGTTATTAG
Streptococcus pneumoniae TIGR4	SP_0576	-169	4.3	ATAAAAACGGTTACAG
Streptococcus pyogenes M1 GAS	SPy0571	-173	4.2	ATTAAAGCGTTCTCAG
Streptococcus suis 05ZYH33	SSU05_1491	-104	4	TTGAAAATGGTTACAG
		-36	4	ATGTTATCGCTTTAAG

Position: -145 Score: 4.8 Sequence: TTGTAAACGTTTTATT Position: -131 Score: 4.3 Sequence: TTTAAAACATTTTCTA Locus tag: SpyoM01000901
	SpyoM01000901	-145	4.8	TTGTAAACGTTTTATT
		-131	4.3	TTTAAAACATTTTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: lacR2
Ortholog function: Lactose phosphotransferase system transcriptional regulator LacR, DeoR family
Streptococcus agalactiae 2603V/R	SAG1936	-199	4	AGTTAAGCGGTTACAT
Streptococcus gallolyticus UCN34	GALLO_0176	-269	4.5	TTAAAAACGTTTTTTT
Streptococcus pyogenes M1 GAS	SPy1924	-145	4.8	TTGTAAACGTTTTATT
		-131	4.3	TTTAAAACATTTTCTA

Position: -34 Score: 5.1 Sequence: TAGAAAGCGTTTTCTA Locus tag: SpyoM01000911
	SpyoM01000911	-34	5.1	TAGAAAGCGTTTTCTA
Supported by regulated orthologs from reference regulons
Ortholog gene name: celR
Ortholog function: Cellobiose utilization transcriptional regulator CelR, BglG family
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1400	-48	4.5	TTGTAAAGGTTTTCTA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1282	-31	5.1	AAGAAAGCGTTTTCTA
Streptococcus gallolyticus UCN34	GALLO_1212	-56	4.9	ATGTAAGCGTTTTTAT
Streptococcus gordonii str. Challis substr. CH1	SGO_1579	-61	4.3	TTGATGGCGTTTTCAT
Streptococcus mutans UA159	SMU.1599	-55	4.8	TTGTAAGCGCTTTTTT
Streptococcus pneumoniae TIGR4	SP_0306	-90	4.5	TTGGAAACGCTTTATT
Streptococcus pyogenes M1 GAS	SPy1325	-34	5.1	TAGAAAGCGTTTTCTA
Streptococcus suis 05ZYH33	SSU05_2076	-67	4.7	CAGAAATCGCTTTCAT
Streptococcus uberis 0140J	SUB0530	-65	4.2	TTGAAAGCGTATACAC

Position: -31 Score: 4.6 Sequence: AGGAAAACGCTTACTT Locus tag: SpyoM01000938
	SpyoM01000938	-31	4.6	AGGAAAACGCTTACTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: glpK
Ortholog function: Glycerol kinase (EC 2.7.1.30)
Streptococcus agalactiae 2603V/R	SAG0273	-31	5	AAGAAAACGCTTACTT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1742	-32	4.9	AAGAAAACGCTTACTA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1603	-59	4.6	TAGAAAGCGCTTGCTA
Streptococcus gordonii str. Challis substr. CH1	SGO_0632	-74	4.8	AAGAAAGCGTTTTATT
Streptococcus mitis B6	smi_2035	-76	4.8	AAGAAAGCGCTTTATT
Streptococcus pneumoniae TIGR4	SP_2186	-75	4.8	AAGAAAGCGCTTTATT
Streptococcus pyogenes M1 GAS	SPy1684	-31	4.6	AGGAAAACGCTTACTT
Streptococcus sanguinis SK36	SSA_1826	-74	4.8	AAGAAAGCGTTTTATT
Streptococcus suis 05ZYH33	SSU05_0722	0	5	ATGGAAGCGTTTTCAA
Streptococcus uberis 0140J	SUB1433	-30	4.3	AAGAAACCGCTTACCT

Position: -195 Score: 4 Sequence: ATTTAAGCACTTTAAA Locus tag: SpyoM01000994
	SpyoM01000994	-195	4	ATTTAAGCACTTTAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: scrK
Ortholog function: Fructokinase (EC 2.7.1.4)
Streptococcus agalactiae 2603V/R	SAG1689	-146	4.3	TAGTAAACGTTTTCTC
		-37	4.5	AATGAAACGCTTTCAA
Streptococcus gallolyticus UCN34	GALLO_1891	-162	4.9	TAGTAAACGTTTTCTT
Streptococcus mitis B6	smi_1614	-52	4.8	ATAAAATCGCTTTCAA
Streptococcus mutans UA159	SMU.1840	-154	4.9	TAGTAAACGTTTTCTT
		-47	4.9	AAAAAAACGCTTTCAA
Streptococcus pneumoniae TIGR4	SP_1721	-52	4.8	ATAAAATCGCTTTCAA
Streptococcus sanguinis SK36	SSA_0457	-157	4.6	TAGTAAACGTTTTCTG
		-49	4.8	ATAAAATCGCTTTCAA
Streptococcus suis 05ZYH33	SSU05_1816	-171	4.9	TAGTAAACGTTTTCTT
		-52	4.8	TTGAAAACACTTTCAA
Streptococcus thermophilus CNRZ1066	str1733	-100	4	AGTGAAACGTTTTCAA

Position: -88 Score: 4.3 Sequence: AGAAAAACGCTTTCTT Locus tag: SpyoM01001005
	SpyoM01001005	-88	4.3	AGAAAAACGCTTTCTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: cas3
Ortholog function: CRISPR-associated helicase Cas3
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0548	-88	4.7	ATGTATGCGTTTACAT
Streptococcus pyogenes M1 GAS	SPy1567	-82	4.3	AGAAAAACGCTTTCTT

Position: -60 Score: 4.7 Sequence: TTGTAAACGATTTCAG Locus tag: SpyoM01001008
	SpyoM01001008	-60	4.7	TTGTAAACGATTTCAG
Supported by regulated orthologs from reference regulons
Ortholog gene name: fruR
Ortholog function: Fructose utilization transcriptional regulator FruR, DeoR family
Lactococcus lactis subsp. cremoris SK11	LACR_1031	-25	4.2	TTGTAAACGAATTCAG
Lactococcus lactis subsp. lactis Il1403	L0031	-25	4.2	TTGTAAACGAATTCAG
Streptococcus agalactiae 2603V/R	SAG1348	-30	4.7	TTGCAAACGATTTCAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0811	-60	4.1	CTGTAACCGATTTCAG
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1106	-62	4.4	CTGTAAACGATTTCAG
Streptococcus gallolyticus UCN34	GALLO_1319	-30	4.4	CTGTAAACGATTTCAG
Streptococcus gordonii str. Challis substr. CH1	SGO_1111	-27	4	ATGTAAGCTGTTTCAG
Streptococcus mutans UA159	SMU.870	22	4.4	GTGTAAACGATTTCAA
Streptococcus pyogenes M1 GAS	SPy0853	-60	4.7	TTGTAAACGATTTCAG
Streptococcus suis 05ZYH33	SSU05_0822	14	4.2	TTGTAAACGGTTGCAG
Streptococcus thermophilus CNRZ1066	str0399	-109	3.8	AGGTTAGCGTTTTATA
		-27	4.5	TTGTAAACGATTACAG
Streptococcus uberis 0140J	SUB0748	-60	4.4	TTGTAACCGATTTCAG

Position: -65 Score: 4.7 Sequence: TTAAAAACGCTTTAAA Locus tag: SpyoM01001027
	SpyoM01001027	-65	4.7	TTAAAAACGCTTTAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ropA
Ortholog function: Cell division trigger factor (EC 5.2.1.8)
Streptococcus agalactiae 2603V/R	SAG0105	-65	4.2	TGTAAAACGTTTTAAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0327	22	4.7	TTAAAAACGCTTTAAA
Streptococcus mutans UA159	SMU.91	-161	4.6	ATGAAAAGGATTTCAT
Streptococcus pneumoniae TIGR4	SP_0400	-53	3.9	TAGAAAATGTTATAAT
Streptococcus pyogenes M1 GAS	SPy1896	-65	4.7	TTAAAAACGCTTTAAA
Streptococcus suis 05ZYH33	SSU05_0328	-65	4	TTGAAATCCTTGTCAA

Position: -35 Score: 4.9 Sequence: ATGAAAGCGTTTATAA Locus tag: SpyoM01001095
	SpyoM01001095	-35	4.9	ATGAAAGCGTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pgm
Ortholog function: Phosphoglucomutase (EC 5.4.2.2)
Streptococcus agalactiae 2603V/R	SAG1066	-35	4.9	ATGAAAGCGTTTATAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1043	-34	4.7	ATGAAAGCGGTTAAAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0941	0	4.7	ATGAAAGCGGTTAAAA
Streptococcus gallolyticus UCN34	GALLO_1123	-39	4.6	ATGAAAGCGTTTAGAA
Streptococcus gordonii str. Challis substr. CH1	SGO_1215	-83	4.4	ATGAAAGCGATTAGAT
Streptococcus mitis B6	smi_1173	-40	4.5	ATGTAAACGATTAAAA
Streptococcus mutans UA159	SMU.1077	-55	4.7	ATGAAAGCGGTTAAAT
Streptococcus pyogenes M1 GAS	SPy1224	-35	4.9	ATGAAAGCGTTTATAA
Streptococcus sanguinis SK36	SSA_1204	-137	4	ATTTCATCGTTTTCTA
Streptococcus suis 05ZYH33	SSU05_0686	-40	4.8	ATGAAAGCGTTTAATA
Streptococcus thermophilus CNRZ1066	str0787	-33	4.8	ATGTAAGCGTTTAAAA
Streptococcus uberis 0140J	SUB0946	-34	4.5	ATGAAAGCGGTTAATA

Position: -53 Score: 4 Sequence: ATTAAAAGGTTTATAA Locus tag: SpyoM01001141
	SpyoM01001141	-53	4	ATTAAAAGGTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rheA
Ortholog function: Cold-shock DEAD-box protein A
Streptococcus agalactiae 2603V/R	SAG0777	-142	4.2	ATGAAAGCGTGTTATT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1455	-146	4.2	ATGAAAACGTGTTATT
		-53	4	ATTAAAAGGTTTATAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0646	-135	4.5	ATAAAAACACTTTCAT
		-53	4	ATTAAAAGGTTTATAA
Streptococcus gallolyticus UCN34	GALLO_0655	-139	4.2	ATGAAAACGTGTTATT
		-116	3.9	ATGAAACTGTTTCCTA
Streptococcus mutans UA159	SMU.611	-127	3.9	TTGAAAACGATCATTT
Streptococcus pyogenes M1 GAS	SPy1415	-199	3.7	CAAAAAACGATATCTT
		-53	4	ATTAAAAGGTTTATAA
Streptococcus suis 05ZYH33	SSU05_1574	-166	4.4	ATGAAAACGTATTATT
Streptococcus uberis 0140J	SUB1250	-70	4.5	ATAAAAACCTTTTCAT

Position: -49 Score: 4.1 Sequence: TAGCAACCGCTTTTAT Locus tag: SpyoM01001205
	SpyoM01001205	-49	4.1	TAGCAACCGCTTTTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pabB
Ortholog function: Para-aminobenzoate synthase component I (EC 4.1.3.-); Anthranilate/para-aminobenzoate synthases component I/ Chorismate binding enzyme, putative
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_0217	-24	4.1	TAGCAACCGCTTTTAT
Streptococcus gordonii str. Challis substr. CH1	SGO_0307	-98	4.8	ATAAAACCGTTTTCAT
		-48	4	AAGAAAACGATTATTG
Streptococcus pyogenes M1 GAS	SPy1990	-30	4.1	TAGCAACCGCTTTTAT
Streptococcus sanguinis SK36	SSA_0413	-147	4	ATTTATTCGATTTCAT
		-44	4.3	ATAAATCCGTTTTCAT

Position: -67 Score: 4.7 Sequence: TAGAAAGCGATTTAAT Locus tag: SpyoM01001376
	SpyoM01001376	-67	4.7	TAGAAAGCGATTTAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: acoA
Ortholog function: Acetoin dehydrogenase E1 component alpha-subunit (EC 1.2.4.-)
Streptococcus agalactiae 2603V/R	SAG0878	-81	4.2	AAGAAAGCGGTTCAAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1250	-67	4.7	AAGAAAGCGATTTAAT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1222	-90	3.9	TTAAAAAAGCTTTTAT
		-67	4.5	AAGAAAGCGATTAAAA
Streptococcus gallolyticus UCN34	GALLO_0867	-99	5	TTTAAAACGTTTTCAA
Streptococcus gordonii str. Challis substr. CH1	SGO_1133	-63	4.4	TTGACAGGGTTTTCAT
Streptococcus mutans UA159	SMU.127	-51	4.1	TAGAAAGCGGTTCAAA
Streptococcus pyogenes M1 GAS	SPy1026	-79	4.7	TAGAAAGCGATTTAAT
Streptococcus sanguinis SK36	SSA_1178	-63	3.8	TTGACAGTGCTTACAG
Streptococcus suis 05ZYH33	SSU05_1841	-36	4.2	AAGAAAACGGTTCAAT
Streptococcus thermophilus CNRZ1066	str1051	-96	4.2	ATGTAAGGCTTTTCAT
Streptococcus uberis 0140J	SUB1103	-80	4.6	TAGAAAGCGGTTTTAA

Position: -168 Score: 4.7 Sequence: AAGAAAGGGTTTTCAA Locus tag: SpyoM01001406
	SpyoM01001406	-168	4.7	AAGAAAGGGTTTTCAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: aphA
Ortholog function: Class B acid phosphatase precursor (EC 3.1.3.2)
Streptococcus agalactiae 2603V/R	SAG0635	-80	4.8	ATGATATCGCTTTCAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124	SDEG_1259	-80	4.8	ATGATATCGCTTTCAT
Streptococcus pyogenes M1 GAS	SPy1113	-168	4.7	AAGAAAGGGTTTTCAA
		-60	4.3	TTGAAACCGCTTTACT

Position: -41 Score: 4.7 Sequence: TTGAAAACCCTTTCTT Locus tag: SpyoM01001407
	SpyoM01001407	-41	4.7	TTGAAAACCCTTTCTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: adh
Ortholog function: Alcohol dehydrogenase, Zn-dependent (EC 1.1.1.1)
Streptococcus agalactiae 2603V/R	SAG1637	-66	4.8	TTGTAACCGCTTTCTT
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_0045	-43	4.7	ATGTAATCGATTACAT
Streptococcus mitis B6	smi_0203	-59	4.7	TTGAAAAGGCTTACAA
Streptococcus pyogenes M1 GAS	SPy1111	-83	4.7	TTGAAAACCCTTTCTT

Position: -61 Score: 4 Sequence: AAGTTGGCGCTTTCAT Locus tag: SpyoM01001442
	SpyoM01001442	-61	4	AAGTTGGCGCTTTCAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: rpiA
Ortholog function: Ribose 5-phosphate isomerase A (EC 5.3.1.6)
Streptococcus agalactiae 2603V/R	SAG1183	-110	4.6	AAGAAAATGTTTTCAA
Streptococcus equi subsp. zooepidemicus MGCS10565	Sez_1165	-61	4.3	AAGTTTGCGCTTTCAT
Streptococcus gordonii str. Challis substr. CH1	SGO_1265	-120	4.3	AGGAAAATGCTTTCAT
Streptococcus pneumoniae TIGR4	SP_0828	-53	4.4	ATAAAAGCCTTTACAT
Streptococcus pyogenes M1 GAS	SPy0889	-171	4	AAGTAAGTGCTTATAT
Streptococcus sanguinis SK36	SSA_1261	-66	4.7	AAGAAAACACTTTCAT
Streptococcus thermophilus CNRZ1066	str1121	-94	4.5	TTGATAGCCTTTTCAT

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of CcpA regulog to Streptococcus pyogenes M49 591

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --