Regulons of Streptococcus pyogenes M49 591



Type	Regulator	Effector	Pathway	Genes	Sites
TF	AdcR	Zinc ion, (Zn2+)	Zinc homeostasis	2	3
TF	AgaR2	N-acetylgalactosamine	N-acetylgalactosamine utilization	1	1
TF	BirA	Biotin	Biotin biosynthesis	1	1
TF	CcpA	Fructose-1,6-bisphosphate; HPr, phosphocarrier protein	Global catabolite repression	37	52
TF	CelR	CelB, cellobiose-specific PTS component EIIB; HPr, phosphocarrier protein	Cellobiose utilization	1	1
TF	CmbR	O-acetyl-L-serine	Cysteine metabolism	3	4
TF	CodY	Guanosine triphosphate; Branched-chain amino acids	Amino acid metabolism	1	1
TF	CopR	Copper ion, (Cu2+)	Copper homeostasis	1	1
TF	FabT	Long-chain acyl-ACP	Fatty acid biosynthesis	1	2
TF	FruR	Fructose-6-phosphate	Fructose utilization	1	3
TF	NagR	N-acetylglucosamine-6-phosphate	N-acetylglucosamine utilization	1	2
TF	NanR	N-acetylneuraminic acid	Sialic acid utilization	1	1
TF	NiaR	Niacin	NAD biosynthesis	2	2
TF	NrdR	Deoxyribonucleotides	Deoxyribonucleotide biosynthesis	2	4
TF	PerR	Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide	Iron homeostasis; Manganese homeostasis; Oxidative stress response	1	1
TF	PflR		Formate metabolism	1	1
TF	PurR	5-phosphoribosyl 1-pyrophosphate	Purine metabolism	4	6
TF	RegR	Hyaluronate oligosaccharide phosphate	Hyaluronate utilization	3	3
TF	Rex	NADH	Energy metabolism	6	10
TF	SAG1910		unknown	1	1
TF	SczA	Zinc ion, (Zn2+)	Zinc resistance	2	2
TF	SgaR	HPr, phosphocarrier protein; SgaB, ascorbate-specific PTS system EIIB component	Ascorbate utilization	3	3
TF	SgaR2	SgaB2, ascorbate-specific PTS system, EIIB component; HPr, phosphocarrier protein	Ascorbate utilization	1	1
TF	SPy1285		Transport	2	2
TF	YjdR		Multidrug resistance	1	1

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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