Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of Rex regulog to Streptococcus pyogenes M49 591

Reference regulog properties
Source regulog: Rex - Streptococcaceae
Regulator type: Transcription factor
Regulator family: Rex
Regulation mode: repressor
Biological process: Energy metabolism
Effector: NADH
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes M49 591
Orthologous TF(s) SpyoM01000613
Regulated genes 6
Built upon 161 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes M49 591
Locus tag Position Score Sequence
Position: -23
Score: 4.6
Sequence: TTGTGAAATGAGGAACAA
Locus tag: SpyoM01000340
SpyoM01000340 -23 4.6 TTGTGAAATGAGGAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: noxE
Ortholog function: NADH oxidase (EC 1.6.99.3)
Streptococcus agalactiae 2603V/R SAG0958 -165 4.3 TTGTGAATTTGTGAAAAA
-59 4.7 TTGTGAATAATGTTATAA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0909 -23 4.6 TTGTGAAATGAGGAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1023 -81 4.3 TTGTGAAATGAGGAACAT
Streptococcus pyogenes M1 GAS SPy1150 -23 4.6 TTGTGAAATGAGGAACAA
Streptococcus thermophilus CNRZ1066 str1281 -91 4.6 TTGTTCAAAAAGTAACAA
Streptococcus uberis 0140J SUB0877 -170 4.6 TTGTGAATTTATGAACTA
-24 4.7 TTGTGAAAAGAGGAACAA
Position: -97
Score: 5.1
Sequence: TTGTGAAAATATTCCTAA
Locus tag: SpyoM01000463
SpyoM01000463 -97 5.1 TTGTGAAAATATTCCTAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: tpi
Ortholog function: Triosephosphate isomerase (EC 5.3.1.1)
Streptococcus agalactiae 2603V/R SAG0763 -72 4 TCGTGAAACTTTTAATTA
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_0629 -97 5.1 TTGTGAAAATATTCCTAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1321 -97 5 TTGTGAAAATATTACTAA
Streptococcus gordonii str. Challis substr. CH1 SGO_0762 -89 4.5 TTGATAAAAACTTAGCAA
Streptococcus pyogenes M1 GAS SPy0613 -97 5.1 TTGTGAAAATATTCCTAA
Streptococcus thermophilus CNRZ1066 str0488 -46 4.7 TTGTGATAAAATAAACGA
Streptococcus uberis 0140J SUB0605 -98 5.2 TTGTGAAAATTATCCCAA
Position: -76
Score: 4.5
Sequence: ATGTTGCATTTTTCACAA
Locus tag: SpyoM01000613
SpyoM01000613 -76 4.5 ATGTTGCATTTTTCACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rex
Ortholog function: Redox-sensitive transcriptional regulator Rex, Rex family
Lactococcus lactis subsp. cremoris SK11 LACR_1156 -74 5.3 TTGATAAAATTATCACAA
Lactococcus lactis subsp. lactis Il1403 L71932 -75 5.3 TTGATAAAATTATCACAA
Streptococcus agalactiae 2603V/R SAG1100 -36 4.5 TAATAAAATTTTTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1050 -31 4.4 TAGTTGCATATTTCACAA
Streptococcus gordonii str. Challis substr. CH1 SGO_1228 -54 4.7 TAGTTGATTTTTTCACAA
Streptococcus mitis B6 smi_1188 -57 5 TTGTTGATTTTTTCACAA
Streptococcus mutans UA159 SMU.1053 -117 4.4 TTGTTATAAAAAAAACTA
-58 4.5 ATGTTGCATTTTTCACAA
Streptococcus pneumoniae TIGR4 SP_1090 -57 5 TTGTTGATTTTTTCACAA
Streptococcus pyogenes M1 GAS SPy1120 -76 4.5 ATGTTGCATTTTTCACAA
Streptococcus sanguinis SK36 SSA_1216 -55 4.7 TAGTTGATTTTTTCACAA
Streptococcus suis 05ZYH33 SSU05_1069 -100 4.5 CTGTTGATTTTTTCACAA
Streptococcus thermophilus CNRZ1066 str1463 -39 4.6 TTGTTGCAATCTTCACAA
Streptococcus uberis 0140J SUB0845 -52 4.4 TTGTTACAATAGTAACAT
Position: -48
Score: 3.8
Sequence: TTTTAAAATATGTTATAA
Position: -39
Score: 4.7
Sequence: ATGTTATAATAGTAACAA
Locus tag: SpyoM01001113
SpyoM01001113 -48 3.8 TTTTAAAATATGTTATAA
-39 4.7 ATGTTATAATAGTAACAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: pncB
Ortholog function: Nicotinate phosphoribosyltransferase (EC 2.4.2.11)
Lactococcus lactis subsp. cremoris SK11 LACR_1202 -218 4 TTGTAGTATAAAAAACAT
Lactococcus lactis subsp. lactis Il1403 L107468 -181 3.9 TTGTAGTACAAAAAACAT
Streptococcus dysgalactiae subsp. equisimilis GGS_124 SDEG_1714 -39 4.7 ATGTTATAATAGTAACAA
Streptococcus equi subsp. zooepidemicus MGCS10565 Sez_1574 -39 4.3 ATGGTATAATAATAACAA
Streptococcus mitis B6 smi_1492 -114 4.3 TTGTTACTCTTTTCTCAA
Streptococcus mutans UA159 SMU.464 -265 4.3 GTGTTATAATAGTAACAA
Streptococcus pneumoniae TIGR4 SP_1421 -114 4.3 TTGTTACTCTTTTCTCAA
Streptococcus pyogenes M1 GAS SPy1653 -39 4.7 ATGTTATAATAGTAACAA