Propagation of MtaR regulog to Streptococcus thermophilus CNRZ1066
| Source regulog: | MtaR - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | LysR |
| Regulation mode: | repressor |
| Biological process: | Methionine metabolism |
| Effector: | Homocysteine |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus thermophilus CNRZ1066 |
| Orthologous TF(s) | str0872 |
| Regulated genes | 9 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -103
Score: 6.3 Sequence: TATAGTTAAAAACTATA
Locus tag: str0297
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| str0297 | -103 | 6.3 | TATAGTTAAAAACTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metQ | ||||
| Ortholog function: Methionine ABC transporter, substrate-binding protein | ||||
| Streptococcus gallolyticus UCN34 | GALLO_1844 | -102 | 6.5 | TATAGTTTTAAACTATA |
| Streptococcus thermophilus CNRZ1066 | str0297 | -103 | 6.3 | TATAGTTAAAAACTATA |
|
Position: -100
Score: 4.5 Sequence: CATAGCCAAAGGCTATA
Locus tag: str0304
|
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| str0304 | -100 | 4.5 | CATAGCCAAAGGCTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: COG1912 | ||||
| Ortholog function: Conserved hypothetical protein | ||||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0468 | -30 | 4.5 | TAAAGTTCAGGACTATA |
| Streptococcus mitis B6 | smi_1812 | -91 | 4.6 | TATAAGGTAAAACTATA |
| Streptococcus mutans UA159 | SMU.1936c | -110 | 5.4 | TATAGGTAATAACTATA |
| Streptococcus pneumoniae TIGR4 | SP_0481 | -64 | 4.6 | TATAAGGTAAAACTATA |
| Streptococcus thermophilus CNRZ1066 | str0304 | -100 | 4.5 | CATAGCCAAAGGCTATA |
| Streptococcus uberis 0140J | SUB0314 | -106 | 6.3 | TATAGTTTTAGACTATA |
|
Position: -140
Score: 5.9 Sequence: TATAGCTTAAAGCTATA
Locus tag: str0334
|
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| str0334 | -140 | 5.9 | TATAGCTTAAAGCTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: COG1878 | ||||
| Ortholog function: Metal-dependent hydrolase (EC 3.-.-.-) | ||||
| Streptococcus gallolyticus UCN34 | GALLO_1176 | -105 | 6.5 | TATAGTTTAAAACTATA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0748 | -152 | 6.3 | TATAGTTATAAACTATA |
| Streptococcus mutans UA159 | SMU.1172c | -66 | 6.3 | TATAGTTTATAACTATA |
| Streptococcus sanguinis SK36 | SSA_1535 | -178 | 6 | TATAGCTTCAAACTATA |
| Streptococcus suis 05ZYH33 | SSU05_0510 | -67 | 5.4 | TATAGTTAAAAGCAATA |
| Streptococcus thermophilus CNRZ1066 | str0334 | -140 | 5.9 | TATAGCTTAAAGCTATA |
|
Position: -130
Score: 5.9 Sequence: TATAGTAATAAACTATA
Locus tag: str0352
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| str0352 | -130 | 5.9 | TATAGTAATAAACTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metB | ||||
| Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48) | ||||
| Streptococcus gallolyticus UCN34 | GALLO_1768 | -140 | 5.2 | TATAGTTTTTACTTATA |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1636 | -101 | 6.1 | TATAGTTTCAGACTATA |
| Streptococcus mitis B6 | smi_1508 | -93 | 6.2 | TATAGTTTGAAACTATA |
| Streptococcus pneumoniae TIGR4 | SP_1525 | -93 | 6.2 | TATAGTTTGAAACTATA |
| Streptococcus sanguinis SK36 | SSA_1737 | -44 | 6.4 | TATAGTTTCAAACTATA |
| Streptococcus thermophilus CNRZ1066 | str0352 | -130 | 5.9 | TATAGTAATAAACTATA |
|
Position: -130
Score: 5.9 Sequence: TATAGTTATTAGCTATA
Position: -58
Score: 6.5 Sequence: TATAGTTTAAAACTATA
Locus tag: str0785
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| str0785 | -130 | 5.9 | TATAGTTATTAGCTATA | |
| -58 | 6.5 | TATAGTTTAAAACTATA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metE | ||||
| Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) | ||||
| Streptococcus agalactiae 2603V/R | SAG2049 | -132 | 6.5 | TATAGTTTAAAACTATA |
| Streptococcus gallolyticus UCN34 | GALLO_1316 | -170 | 6.3 | TATAGTTAAAAACTATA |
| -139 | 5.9 | TATAGCTAAAAACTATA | ||
| -36 | 5.2 | TATAGTTTAAAACTAAT | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0310 | -180 | 5.4 | TATAGTTTTTGATTATA |
| -97 | 5.9 | TATAGTTTTTGGCTATA | ||
| Streptococcus mitis B6 | smi_1600 | -99 | 6.4 | TATAGTTTCAAACTATA |
| Streptococcus mutans UA159 | SMU.873 | -186 | 5.6 | TATAGATGAAAACTATA |
| -155 | 6.1 | TATAGCTTAAAACTATA | ||
| Streptococcus pneumoniae TIGR4 | SP_0585 | -99 | 6.4 | TATAGTTTCAAACTATA |
| Streptococcus sanguinis SK36 | SSA_0416 | -180 | 4.8 | CATAATTTCTACCTATA |
| -97 | 6.3 | TATAGTTTTAGACTATA | ||
| Streptococcus suis 05ZYH33 | SSU05_1774 | -235 | 5.2 | CATAGATAAAATCTATA |
| -99 | 4.8 | TATAGTCAAAAGTTATA | ||
| Streptococcus thermophilus CNRZ1066 | str0785 | -130 | 5.9 | TATAGTTATTAGCTATA |
| -58 | 6.5 | TATAGTTTAAAACTATA | ||
|
Position: -257
Score: 5.9 Sequence: TATAGTCTAAAACTATA
Locus tag: str0905
|
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| str0905 | -257 | 5.9 | TATAGTCTAAAACTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metE2 | ||||
| Ortholog function: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) | ||||
| Streptococcus mutans UA159 | SMU.1487 | -100 | 6.5 | TATAGTTTAAAACTATA |
| Streptococcus sanguinis SK36 | SSA_0917 | -83 | 5.2 | AATAGTTTTCGGCTATA |
| Streptococcus thermophilus CNRZ1066 | str0905 | -257 | 5.9 | TATAGTCTAAAACTATA |
|
Position: -103
Score: 5.6 Sequence: TATAGTTTAAAGTTATA
Locus tag: str1222
|
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| str1222 | -103 | 5.6 | TATAGTTTAAAGTTATA | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: metA | ||||
| Ortholog function: Homoserine O-succinyltransferase (EC 2.3.1.46) | ||||
| Streptococcus gallolyticus UCN34 | GALLO_0824 | -105 | 5.9 | TATAGCTAAAAACTATA |
| -71 | 5.4 | TATAATTGAAAACTATA | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1002 | -97 | 5.6 | CATAGTTTCAGGCTATA |
| -63 | 5.4 | TATAATTGAAAACTATA | ||
| Streptococcus mutans UA159 | SMU.1466 | -102 | 5.3 | TATAGTTGGAACCTATA |
| -68 | 5.2 | TATATTTGATAACTATA | ||
| Streptococcus pneumoniae TIGR4 | SP_1576 | -109 | 5.4 | TATAATTGAAAACTATA |
| Streptococcus sanguinis SK36 | SSA_1420 | -145 | 5.8 | CATAGTTTCTAACTATA |
| -111 | 5.4 | TATAATTGAAAACTATA | ||
| Streptococcus thermophilus CNRZ1066 | str1222 | -103 | 5.6 | TATAGTTTAAAGTTATA |