Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of MtaR regulog to Streptococcus gordonii str. Challis substr. CH1

Reference regulog properties
Source regulog: MtaR - Streptococcaceae
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: repressor
Biological process: Methionine metabolism
Effector: Homocysteine
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus gordonii str. Challis substr. CH1
Orthologous TF(s) SGO_1257
Regulated genes 7
Built upon 72 sites [see more]
Predicted regulatory interactions in Streptococcus gordonii str. Challis substr. CH1
Locus tag Position Score Sequence
Position: -180
Score: 5.4
Sequence: TATAGTTTTTGATTATA
Position: -97
Score: 5.9
Sequence: TATAGTTTTTGGCTATA
Locus tag: SGO_0310
SGO_0310 -180 5.4 TATAGTTTTTGATTATA
-97 5.9 TATAGTTTTTGGCTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE
Ortholog function: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Streptococcus agalactiae 2603V/R SAG2049 -132 6.5 TATAGTTTAAAACTATA
Streptococcus gallolyticus UCN34 GALLO_1316 -170 6.3 TATAGTTAAAAACTATA
-139 5.9 TATAGCTAAAAACTATA
-36 5.2 TATAGTTTAAAACTAAT
Streptococcus gordonii str. Challis substr. CH1 SGO_0310 -180 5.4 TATAGTTTTTGATTATA
-97 5.9 TATAGTTTTTGGCTATA
Streptococcus mitis B6 smi_1600 -99 6.4 TATAGTTTCAAACTATA
Streptococcus mutans UA159 SMU.873 -186 5.6 TATAGATGAAAACTATA
-155 6.1 TATAGCTTAAAACTATA
Streptococcus pneumoniae TIGR4 SP_0585 -99 6.4 TATAGTTTCAAACTATA
Streptococcus sanguinis SK36 SSA_0416 -180 4.8 CATAATTTCTACCTATA
-97 6.3 TATAGTTTTAGACTATA
Streptococcus suis 05ZYH33 SSU05_1774 -235 5.2 CATAGATAAAATCTATA
-99 4.8 TATAGTCAAAAGTTATA
Streptococcus thermophilus CNRZ1066 str0785 -130 5.9 TATAGTTATTAGCTATA
-58 6.5 TATAGTTTAAAACTATA
Position: -179
Score: 4.8
Sequence: TATACAAAAAAACTATA
Position: -30
Score: 4.5
Sequence: TAAAGTTCAGGACTATA
Locus tag: SGO_0468
SGO_0468 -179 4.8 TATACAAAAAAACTATA
-30 4.5 TAAAGTTCAGGACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: COG1912
Ortholog function: Conserved hypothetical protein
Streptococcus gordonii str. Challis substr. CH1 SGO_0468 -30 4.5 TAAAGTTCAGGACTATA
Streptococcus mitis B6 smi_1812 -91 4.6 TATAAGGTAAAACTATA
Streptococcus mutans UA159 SMU.1936c -110 5.4 TATAGGTAATAACTATA
Streptococcus pneumoniae TIGR4 SP_0481 -64 4.6 TATAAGGTAAAACTATA
Streptococcus thermophilus CNRZ1066 str0304 -100 4.5 CATAGCCAAAGGCTATA
Streptococcus uberis 0140J SUB0314 -106 6.3 TATAGTTTTAGACTATA
Position: -152
Score: 6.3
Sequence: TATAGTTATAAACTATA
Locus tag: SGO_0747
SGO_0747 -152 6.3 TATAGTTATAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metE2
Ortholog function: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
Streptococcus gordonii str. Challis substr. CH1 SGO_0747 -152 6.3 TATAGTTATAAACTATA
Position: -158
Score: 5.8
Sequence: TATAGTTTATGTCTATA
Locus tag: SGO_0987
SGO_0987 -158 5.8 TATAGTTTATGTCTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metK
Ortholog function: S-adenosylmethionine synthetase (EC 2.5.1.6)
Streptococcus gordonii str. Challis substr. CH1 SGO_0987 -158 5.8 TATAGTTTATGTCTATA
Streptococcus sanguinis SK36 SSA_1495 -157 6.3 TATAGTTTTAATCTATA
Position: -97
Score: 5.6
Sequence: CATAGTTTCAGGCTATA
Position: -63
Score: 5.4
Sequence: TATAATTGAAAACTATA
Locus tag: SGO_1002
SGO_1002 -97 5.6 CATAGTTTCAGGCTATA
-63 5.4 TATAATTGAAAACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metA
Ortholog function: Homoserine O-succinyltransferase (EC 2.3.1.46)
Streptococcus gallolyticus UCN34 GALLO_0824 -105 5.9 TATAGCTAAAAACTATA
-71 5.4 TATAATTGAAAACTATA
Streptococcus gordonii str. Challis substr. CH1 SGO_1002 -97 5.6 CATAGTTTCAGGCTATA
-63 5.4 TATAATTGAAAACTATA
Streptococcus mutans UA159 SMU.1466 -102 5.3 TATAGTTGGAACCTATA
-68 5.2 TATATTTGATAACTATA
Streptococcus pneumoniae TIGR4 SP_1576 -109 5.4 TATAATTGAAAACTATA
Streptococcus sanguinis SK36 SSA_1420 -145 5.8 CATAGTTTCTAACTATA
-111 5.4 TATAATTGAAAACTATA
Streptococcus thermophilus CNRZ1066 str1222 -103 5.6 TATAGTTTAAAGTTATA
Position: -42
Score: 4.8
Sequence: TTTTGTTATAATCTATA
Locus tag: SGO_1210
SGO_1210 -42 4.8 TTTTGTTATAATCTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: fhs
Ortholog function: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
Streptococcus gordonii str. Challis substr. CH1 SGO_1210 -42 4.8 TTTTGTTATAATCTATA
Streptococcus mitis B6 smi_1192 -157 6.4 TATAGTTTCAAACTATA
Streptococcus pneumoniae TIGR4 SP_1229 -156 6.4 TATAGTTTCAAACTATA
Streptococcus uberis 0140J SUB0942 -129 4.6 TAAAGATATACACTATA
Position: -101
Score: 6.1
Sequence: TATAGTTTCAGACTATA
Locus tag: SGO_1636
SGO_1636 -101 6.1 TATAGTTTCAGACTATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: metB
Ortholog function: Cystathionine gamma-synthase (EC 2.5.1.48)
Streptococcus gallolyticus UCN34 GALLO_1768 -140 5.2 TATAGTTTTTACTTATA
Streptococcus gordonii str. Challis substr. CH1 SGO_1636 -101 6.1 TATAGTTTCAGACTATA
Streptococcus mitis B6 smi_1508 -93 6.2 TATAGTTTGAAACTATA
Streptococcus pneumoniae TIGR4 SP_1525 -93 6.2 TATAGTTTGAAACTATA
Streptococcus sanguinis SK36 SSA_1737 -44 6.4 TATAGTTTCAAACTATA
Streptococcus thermophilus CNRZ1066 str0352 -130 5.9 TATAGTAATAAACTATA